Miller Fisher syndrome

Common Name(s)

Miller Fisher syndrome

Miller-Fisher syndrome is a rare, acquired nerve disease that is considered to be a variant of Guillain-BarrŽ syndrome. It is characterized by abnormal muscle coordination, paralysis of the eye muscles, and absence of the tendon reflexes. Like Guillain-BarrŽ syndrome, symptoms may be preceded by a viral illness. Additional symptoms include generalized muscle weakness and respiratory failure. The majority of individuals with Miller-Fisher syndrome have a unique antibody that characterizes the disorder. Treatment includes intravenous immunoglobulin (IVIg) or plasmapheresis (a procedure in which antibodies are removed from the blood) and supportive care.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Miller Fisher syndrome" for support, advocacy or research.

GBS/CIDP Foundation International

To improve the quality of life for individuals and families worldwide affected by GBS, CIDP and variants by: Providing a network for all patients, their caregivers and families so that GBS or CIDP patients can depend on the Foundation for support, and reliable up-to-date information. Providing public and professional educational programs worldwide designed to heighten awareness and improve the understanding and treatment of GBS, CIDP and variants. Expanding the Foundation’s role in sponsoring research and engaging in patient advocacy.

Last Updated: 19 Feb 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Miller Fisher syndrome" for support, advocacy or research.

GBS/CIDP Foundation International

To improve the quality of life for individuals and families worldwide affected by GBS, CIDP and variants by: Providing a network for all patients, their caregivers and families so that GBS or CIDP patients can depend on the Foundation for support, and reliable up-to-date information. Providing public and professional educational programs worldwide designed to heighten awareness and improve the understanding and treatment of GBS, CIDP and variants. Expanding the Foundation’s role in sponsoring research and engaging in patient advocacy.

http://www.gbs-cidp.org

Last Updated: 19 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Miller Fisher syndrome" returned 64 free, full-text research articles on human participants. First 3 results:

Cerebral infarction 3 weeks after intravenous immunoglobulin for Miller Fisher syndrome: a case report.
 

Author(s): Thashi Chang, Johann Shenoj de Alwis, Neirosha Samarasekara, Senaka Rajapakse

Journal:

 

Intravenous immunoglobulin is considered generally safe and is used widely as proven, and sometimes empiric, treatment for an expanding list of autoimmune diseases. Thromboembolic complications following intravenous immunoglobulin therapy are rare and there have been only five previous ...

Last Updated: 3 Jun 2014

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[Miller Fisher syndrome with anti GQ1b negative in Mycoplasma pneumoniae pneumonia].
 

Author(s): Victor Sini, Calixte Kuate Tegueu, Séraphin Nguefack, Mathieu Boone, Richard Roos-Weil

Journal:

 

Last Updated: 22 Nov 2013

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A case of atypical Miller Fisher syndrome with negative anti-GQ1b immunoglobulin G and importance of H reflex.
 

Author(s): Uluç Yiş, Erhan Bayram, Yasemin Topçu, Pakize Karakaya, Semra Hız Kurul

Journal: Turk. J. Pediatr.. ;55(2):235-6.

 

Last Updated: 6 Nov 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Miller Fisher syndrome" returned 2 free, full-text review articles on human participants. First 3 results:

Miller Fisher syndrome in adult onset Still's disease: case report and review of the literature of other neurological manifestations.
 

Author(s): S S Desai, E Allen, A Deodhar

Journal: Rheumatology (Oxford). 2002 Feb;41(2):216-22.

 

Adult-onset Still's disease (AOSD) is a multi-system inflammatory disorder characterized by high spiking fevers, evanescent salmon-coloured rash, arthralgias or arthritis, hepatosplenomegaly, lymphadenopathy and sore throat. There is no specific test or combination of tests that can ...

Last Updated: 11 Mar 2002

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Molecular mimicry between gangliosides and lipopolysaccharides of Campylobacter jejuni isolated from patients with Guillain-Barré syndrome and Miller Fisher syndrome.
 

Author(s): N Yuki

Journal: J. Infect. Dis.. 1997 Dec;176 Suppl 2():S150-3.

 

Some patients developed Guillain-Barré syndrome (GBS) after being given bovine gangliosides. Patients with GBS subsequent to Campylobacter jejuni enteritis frequently have IgG antibody to GM1 ganglioside. Miller Fisher syndrome (MFS), a variant of GBS, is associated with IgG antibody ...

Last Updated: 15 Jan 1998

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

International Guillain-Barré Syndrome Outcome Study
 

Status: Recruiting

Condition Summary: Guillain-Barré Syndrome; Miller Fisher Syndrome

 

Last Updated: 26 Nov 2013

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