Migraine

Common Name(s)

Migraine

A migraine is a severe headache that can cause intense throbbing or a pulsing sensation in your head. Environmental and genetic factors may play a role in causing migraines. Migraine headaches often begin in childhood, adolescence or early adulthood and may consist of four stages, prodrome, aura, headache, and postdrome.

Prodrome may occur one or two days before a migraine and are subtle changes in food craving, activity, irritability, neck stiffness, depression, constipation, and uncontrollable yawning. Aura may occur before or during migraine headaches. Symptoms of aura may include vision loss, bright spots, and speech problems (apshasia). During the migraine attack symptoms may include throbbing pain in sides of your head, sensitivity to light, sound, and sometimes smells, nausea, vomiting, blurred vision, and lightheadedness. Postdrome is the last phase that occurs after a migraine attack where you may feel drained and washed out.

Migraine headache triggers may include, food, caffeinated and alcoholic drinks, stress, sensory stimuli, changes in wake-sleep pattern, physical factors, changes in the environment, hormonal changes in women, and medications. Risk factors may include family history, age, sex, and hormonal changes. Your doctor may diagnose your condition based on your medical history, symptoms and a physical and neurological examination. To rule out other possible causes for your pain your doctor may perform blood tests, computerized tomography (CT) scan, magnetic resonance imaging (MRI) and or a spinal tap (lumbar puncture). If you or someone you know suffers from migraines talk to your doctor to learn how to manage your condition.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Migraine" for support, advocacy or research.

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National Headache Foundation

The National Headache Foundation exists to enhance the healthcare of individuals with headache. It is a source of help to their families, physicians and allied healthcare professionals who treat them, and to the public. The NHF accomplishes its mission by providing educational and informational resources, supporting headache research, and advocating for the understanding of headache as a legitimate neurobiological disease.

Last Updated: 16 Mar 2015

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APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

Last Updated: 12 Aug 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Migraine" for support, advocacy or research.

Logo
National Headache Foundation

The National Headache Foundation exists to enhance the healthcare of individuals with headache. It is a source of help to their families, physicians and allied healthcare professionals who treat them, and to the public. The NHF accomplishes its mission by providing educational and informational resources, supporting headache research, and advocating for the understanding of headache as a legitimate neurobiological disease.

http://www.headaches.org

Last Updated: 16 Mar 2015

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APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

http://www.apsfa.org

Last Updated: 12 Aug 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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General Resources

Migraine Signs and Symptoms

A migraine is a throbbing or pulsating headache that is often one sided (unilateral) and associated with nausea; vomiting; sensitivity to light, sound, and smells; sleep disruption; and depression. Attacks are often recurrent and tend to become less

Updated 13 Nov 2012

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APS Foundation of America, Inc Fan Page

The APS Foundation of America, Inc. is the leading United States nonprofit health agency dedicated to bringing national awareness to Antiphospholipid Antibody Syndrome (APS).

Updated 13 Nov 2012

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Blogs

APS Friends & Support Forum

Are you looking for Support for Antiphospholipid Antibody Syndrome, APS, APLS, APLA, Hughes Syndrome, or Sticky Blood? Well you've come to the right place! This is an private forum for people who have Antiphospholipid Antibody Syndrome, friends, fam

Updated 13 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Migraine" returned 1741 free, full-text research articles on human participants. First 3 results:

A Nationwide Population-Based Cohort Study of Migraine and Organic-Psychogenic Erectile Dysfunction.
 

Author(s): Szu-Hsien Wu, Eric Chuang, Tien-Yow Chuang, Cheng-Li Lin, Ming-Chia Lin, Der-Jen Yen, Chia-Hung Kao

Journal: Medicine (Baltimore). 2016 Mar;95(10):e3065.

 

As chronic illnesses and chronic pain are related to erectile dysfunction (ED), migraine as a prevalent chronic disorder affecting lots of people all over the world may negatively affect quality of life as well as sexual function. However, a large-scale population-based study of erectile ...

Last Updated: 11 Mar 2016

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Risk of Migraine in Patients With Asthma: A Nationwide Cohort Study.
 

Author(s): Yi-Hao Peng, Kuan-Fei Chen, Chia-Hung Kao, Hsuan-Ju Chen, Te-Chun Hsia, Chia-Hung Chen, Wei-Chih Liao

Journal: Medicine (Baltimore). 2016 Mar;95(9):e2911.

 

Asthma has been described as an "acephalic migraine" and "pulmonary migraine." However, no study has investigated the temporal frequency of migraine development in patients with asthma, and the results of previous studies may be difficult to generalize.We investigated the effect of ...

Last Updated: 6 Mar 2016

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Gene co-expression analysis identifies brain regions and cell types involved in migraine pathophysiology: a GWAS-based study using the Allen Human Brain Atlas.
 

Author(s): Else Eising, Sjoerd M H Huisman, Ahmed Mahfouz, Lisanne S Vijfhuizen, Verneri Anttila, Bendik S Winsvold, Tobias Kurth, M Arfan Ikram, Tobias Freilinger, Jaakko Kaprio, Dorret I Boomsma, Cornelia M van Duijn, Marjo-Riitta R Järvelin, John-Anker Zwart, Lydia Quaye, David P Strachan, Christian Kubisch, Martin Dichgans, George Davey Smith, Kari Stefansson, Aarno Palotie, Daniel I Chasman, Michel D Ferrari, Gisela M Terwindt, Boukje de Vries, Dale R Nyholt, Boudewijn P F Lelieveldt, Arn M J M van den Maagdenberg, Marcel J T Reinders

Journal: Hum. Genet.. 2016 Apr;135(4):425-39.

 

Migraine is a common disabling neurovascular brain disorder typically characterised by attacks of severe headache and associated with autonomic and neurological symptoms. Migraine is caused by an interplay of genetic and environmental factors. Genome-wide association studies (GWAS) ...

Last Updated: 17 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Migraine" returned 304 free, full-text review articles on human participants. First 3 results:

[Current pharmacotherapy in migraine].
 

Author(s): Éva Csépány, Máté Magyar, Tamás Gyüre, György Bozsik, Csaba Ertsey

Journal: Neuropsychopharmacol Hung. 2015 Dec;17(4):169-76.

 

The exact pathomechanism of migraine is still unknown, currently there are no biomarkers for migraine diagnosis, and current animal models reflect only one aspect of migraine, therefore future migraine studies are necessary. The current treatment of migraine (both acute and preventive) ...

Last Updated: 5 Jan 2016

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New players in the preventive treatment of migraine.
 

Author(s): Dimos D Mitsikostas, Alan M Rapoport

Journal:

 

Migraine is a common, chronic disorder of the brain causing much disability, as well as personal, familial and societal impact. Several oral preventive agents are available in different countries for the prevention of migraine, but none have performed better than 50% improvement in ...

Last Updated: 11 Nov 2015

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[Arterial pathology in migraine: endothelial dysfunction and structural changes in the brain and systemic vasculature].
 

Author(s): Davinia Larrosa-Campo, César Ramón-Carbajo, Rocío Álvarez-Escudero, Eva Cernuda-Morollón, Carmen García-Cabo, Julio Pascual

Journal: Rev Neurol. 2015 Oct;61(7):313-22.

 

The pathophysiology underlying the association between migraine and other non-atherosclerotic vascular diseases is largely unknown. Endothelial dysfunction has been proposed as a common link. Besides, endothelial dysfunction is considered as a predictor of structural changes in the arterial walls.

Last Updated: 28 Sep 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Efficacy and Safety of Intra-oral Topical Ketoprofen for the Treatment of Acute Migraine
 

Status: Not yet recruiting

Condition Summary: Migraine Disorders; Migraine Headache; Migraine; Acute Migraine

 

Last Updated: 4 Jun 2011

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The Impact of Triptan and Doxycycline on Neuroinflammatory Biomarkers in Acute Migraine
 

Status: Recruiting

Condition Summary: Migraine Disorders; Headache, Migraine; Migraine; Migraine Headache; Migraine With Aura; Migraine Without Aura; Headache Disorders, Primary

 

Last Updated: 20 Apr 2014

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Preventive Treatment of Episodic and Chronic Migraine
 

Status: Not yet recruiting

Condition Summary: Migraine With Aura; Migraine Without Aura; Chronic Migraine

 

Last Updated: 18 Mar 2011

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