Microscopic polyangiitis

Common Name(s)

Microscopic polyangiitis

Microscopic polyangiitis (MPA) is a disorder that causes blood vessel inflammation (vasculitis), which can lead to organ damage.  The kidneys, lungs, nerves, skin, and joints are the most commonly affected areas of the body. MPA is diagnosed in people of all ages, all ethnicities, and both genders. The cause of this disorder is unknown.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Microscopic polyangiitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Microscopic polyangiitis" returned 84 free, full-text research articles on human participants. First 3 results:

A case of microscopic polyangiitis with skin manifestations in a seven-year-old girl.
 

Author(s): Yozo Yamada, Chie Kitagawa, Ichiro Kamioka, Ko-Ron Chen, Masahiro Oka

Journal:

 

A case of a 7-year-old girl with microscopic polyangiitis (MPA) with a skin eruption characterized by maculopapular, erythematous and purpuric lesions on the face, elbows, and knees is presented. Anti-neutrophil cytoplasmic autoantibodies (ANCA) with myeloperoxidase specificity (MPO-ANCA) ...

Last Updated: 20 Sep 2013

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Prediction of response to treatment by gene expression profiling of peripheral blood in patients with microscopic polyangiitis.
 

Author(s): Akihiro Ishizu, Utano Tomaru, Taichi Murai, Tomohiro Yamamoto, Tatsuya Atsumi, Takashi Yoshiki, Wako Yumura, Kunihiro Yamagata, Hidehiro Yamada, Shunichi Kumagai, Manae S Kurokawa, Machi Suka, Hirofumi Makino, Shoichi Ozaki,

Journal:

 

The JMAAV study was an open-labeled prospective clinical trial, which proposed severity-based treatment protocols for patients with microscopic polyangiitis (MPA). The results suggest that the proposed protocols are useful (remission rate: 89.4%), but are also indicative of relapse ...

Last Updated: 21 May 2013

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The first Korean case of disseminated mycetoma caused by Nocardia pseudobrasiliensis in a patient on long-term corticosteroid therapy for the treatment of microscopic polyangiitis.
 

Author(s): Chang-Ahn Seol, Heungsup Sung, Duck-Hee Kim, Misuk Ji, Yong-Pil Chong, Mi-Na Kim

Journal: Ann Lab Med. 2013 May;33(3):203-7.

 

Nocardia pseudobrasiliensis is predominantly associated with invasive infections in immunocompromised patients. We report a case of disseminated mycetoma caused by N. pseudobrasiliensis in a 57-yr-old woman with microscopic polyangiitis, who was treated for 3 months with corticosteroids. ...

Last Updated: 13 May 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Microscopic polyangiitis" returned 10 free, full-text review articles on human participants. First 3 results:

Cyclophosphamide as induction therapy for Wegener's granulomatosis and microscopic polyangiitis.
 

Author(s): C A Langford

Journal: Clin. Exp. Immunol.. 2011 May;164 Suppl 1():31-4.

 

The introduction of cyclophosphamide (CyP) as a treatment for Wegener's granulomatosis (WG) and microscopic polyangiitis (MPA) has been among the most significant contributions in vasculitis. Prior to the introduction of CyP, WG was a uniformly fatal disease, with mortality occurring ...

Last Updated: 30 Mar 2011

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Overall survival, renal survival and relapse in patients with microscopic polyangiitis: a systematic review of current evidence.
 

Author(s): Luis Corral-Gudino, María Borao-Cengotita-Bengoa, Javier Del Pino-Montes, José L Lerma-Márquez

Journal: Rheumatology (Oxford). 2011 Aug;50(8):1414-23.

 

There are limited data on the long-term prognosis of microscopic polyangiitis (MPA). A systematic review was performed to estimate the survival, renal survival and relapse rates in patients with MPA.

Last Updated: 12 Jul 2011

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Microscopic polyangiitis.
 

Author(s): Sharon A Chung, Philip Seo

Journal: Rheum. Dis. Clin. North Am.. 2010 Aug;36(3):545-58.

 

In 1923, Friedrich Wohlwill described two patients with a "microscopic form of periarteritis nodosa," which was distinct from the classical form. This disease, now known as microscopic polyangiitis (MPA), is a primary systemic vasculitis characterized by inflammation of the small-caliber ...

Last Updated: 6 Aug 2010

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Longitudinal Protocol for Granulomatosis With Polyangiitis (Wegener's) and Microscopic Polyangiitis
 

Status: Recruiting

Condition Summary: Granulomatosis With Polyangiitis; Microscopic Polyangiitis; Wegener's

 

Last Updated: 22 Nov 2013

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Last Updated: 7 Jul 2014

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Observation Study of Clinical Manifestation and Outcome in Chinese Patients With Pulmonary Vasculitis
 

Status: Not yet recruiting

Condition Summary: ANCA-associated Vasculitis; Granulomatosis With Polyangiitis; Microscopic Polyangiitis; EosinphilicGranulomatosis With Polyangiitis

 

Last Updated: 27 Apr 2014

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