Microscopic polyangiitis

Common Name(s)

Microscopic polyangiitis

Microscopic polyangiitis (MPA) is a disorder that causes blood vessel inflammation (vasculitis), which can lead to organ damage.  The kidneys, lungs, nerves, skin, and joints are the most commonly affected areas of the body. MPA is diagnosed in people of all ages, all ethnicities, and both genders. The cause of this disorder is unknown.
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Microscopic polyangiitis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Microscopic polyangiitis" returned 87 free, full-text research articles on human participants. First 3 results:

A retrospective study of microscopic polyangiitis patients presenting with pulmonary fibrosis in China.
 

Author(s): Hui Huang, Yan Xun Wang, Chun Guo Jiang, Jia Liu, Ji Li, Kai Xu, Zuo Jun Xu

Journal:

 

Pulmonary involvement is a common feature of MPA. Although alveolar hemorrhage is the most common pulmonary manifestation of MPA, a few recent studies have described instances of MPA patients with pulmonary fibrosis. Pulmonary fibrosis was seen to predate, be concomitant with, or ...

Last Updated: 6 Feb 2014

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Long-term outcome and efficacy of cyclophosphamide therapy in Japanese patients with ANCA-associated microscopic polyangiitis: a retrospective study.
 

Author(s): Izaya Nakaya, Mayumi Yahata, Satoko Takahashi, Tomomi Sasajima, Tsutomu Sakuma, Yugo Shibagaki, Jun Soma

Journal: Intern. Med.. 2013 ;52(22):2503-9.

 

The aim of this study was to elucidate the efficacy of cyclophosphamide (CY) in Japanese patients with antineutrophil cystoplasmic antibody (ANCA)-associated microscopic polyangiitis (MPA).

Last Updated: 18 Nov 2013

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A case of microscopic polyangiitis with skin manifestations in a seven-year-old girl.
 

Author(s): Yozo Yamada, Chie Kitagawa, Ichiro Kamioka, Ko-Ron Chen, Masahiro Oka

Journal:

 

A case of a 7-year-old girl with microscopic polyangiitis (MPA) with a skin eruption characterized by maculopapular, erythematous and purpuric lesions on the face, elbows, and knees is presented. Anti-neutrophil cytoplasmic autoantibodies (ANCA) with myeloperoxidase specificity (MPO-ANCA) ...

Last Updated: 20 Sep 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Microscopic polyangiitis" returned 10 free, full-text review articles on human participants. First 3 results:

Cyclophosphamide as induction therapy for Wegener's granulomatosis and microscopic polyangiitis.
 

Author(s): C A Langford

Journal: Clin. Exp. Immunol.. 2011 May;164 Suppl 1():31-4.

 

The introduction of cyclophosphamide (CyP) as a treatment for Wegener's granulomatosis (WG) and microscopic polyangiitis (MPA) has been among the most significant contributions in vasculitis. Prior to the introduction of CyP, WG was a uniformly fatal disease, with mortality occurring ...

Last Updated: 30 Mar 2011

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Overall survival, renal survival and relapse in patients with microscopic polyangiitis: a systematic review of current evidence.
 

Author(s): Luis Corral-Gudino, María Borao-Cengotita-Bengoa, Javier Del Pino-Montes, José L Lerma-Márquez

Journal: Rheumatology (Oxford). 2011 Aug;50(8):1414-23.

 

There are limited data on the long-term prognosis of microscopic polyangiitis (MPA). A systematic review was performed to estimate the survival, renal survival and relapse rates in patients with MPA.

Last Updated: 12 Jul 2011

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Microscopic polyangiitis.
 

Author(s): Sharon A Chung, Philip Seo

Journal: Rheum. Dis. Clin. North Am.. 2010 Aug;36(3):545-58.

 

In 1923, Friedrich Wohlwill described two patients with a "microscopic form of periarteritis nodosa," which was distinct from the classical form. This disease, now known as microscopic polyangiitis (MPA), is a primary systemic vasculitis characterized by inflammation of the small-caliber ...

Last Updated: 6 Aug 2010

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Longitudinal Protocol for Granulomatosis With Polyangiitis (Wegener's) and Microscopic Polyangiitis
 

Status: Recruiting

Condition Summary: Granulomatosis With Polyangiitis; Microscopic Polyangiitis; Wegener's

 

Last Updated: 22 Nov 2013

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Last Updated: 3 Nov 2014

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Observation Study of Clinical Manifestation and Outcome in Chinese Patients With Pulmonary Vasculitis
 

Status: Not yet recruiting

Condition Summary: ANCA-associated Vasculitis; Granulomatosis With Polyangiitis; Microscopic Polyangiitis; EosinphilicGranulomatosis With Polyangiitis

 

Last Updated: 27 Apr 2014

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