Microcystic adnexal carcinoma

Common Name(s)

Microcystic adnexal carcinoma

Microcystic adnexal carcinoma is a rare type of cancer that usually develops in areas of the body where sweat is produced (sweat glands). The largest of these sweat-producing sites and also the most common location where microcystic adnexal carcinoma develops is the central face. The cancer forms when a change (mutation) in DNA causes certain cells to grow out of control, sometimes forming a lump or a tumor. Microcystic adnexal carcinoma may also occur in the general head and neck regions. Some of these cancerous cells can break off and spread ("metastasize") to other parts of the body and grow there.

Microcystic adnexal carcinoma most commonly occurs in adults between the ages of 40 and 60, though it can appear in all age groups. Factors that may increase the risk of developing microcystic adnexal carcinoma include excess exposure to sunlight, sunburn, and a family history of skin cancer. The most common symptoms of microcystic adnexal carcinoma include redness, inflammation, and irritation of the skin. There can also be a cyst-like growth near the neck, mouth, or cheek areas, which may or may not be painful. Diagnoses are made usually with a combination of a physical exam, imaging studies, and other laboratory studies.

Treatment for microcystic adnexal carcinoma depends on many factors such as how large the cancer growth is and if it has spread to other areas of the body. If you or a family member has been diagnosed with microcystic adnexal carcinoma, talk to your doctor and specialists about the most current treatment options. Support groups are also available for more resources and information.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Microcystic adnexal carcinoma" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Microcystic adnexal carcinoma" returned 9 free, full-text research articles on human participants. First 3 results:

Microcystic adnexal carcinoma simulating scarring alopecia.
 

Author(s): Maria Christina Marques Nogueira Castanon, Sandra Maria Gasparete Casali, Raul Fernando Binato Lamim, Marina Vieira Nagahama, Camila Bastos Xavier Vassimon Silva, Rafael Guerra Nannetti de Carvalho

Journal: An Bras Dermatol. ;90(3 Suppl 1):36-8.

 

The microcystic adnexal carcinoma is a rare, locally aggressive malignant adnexal neoplasm associated with significant morbidity. It is often underdiagnosed due to clinical and histopathological resemblance with other cutaneous neoplasms and/or a combination of lack of familiarity ...

Last Updated: 28 Aug 2015

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Microcystic adnexal carcinoma of the upper lip misdiagnosed benign desmoplastic trichoepithelioma.
 

Author(s): Jan Rustemeyer, Stefan Zwerger, Matthies Pörksen, Klaus Junker

Journal: Oral Maxillofac Surg. 2013 Jun;17(2):141-4.

 

Desmoplastic trichoepithelioma (DT) is a benign appendageal tumour predominately localized on the facial skin. The histological diagnosis can be difficult in some cases. Partial malignant transformation of a DT is a rarity and a complete transformation has never been described in literature.

Last Updated: 22 May 2013

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A brownish-grey plaque with ulceration on the nasolabial area: a quiz. Microcystic adnexal carcinoma.
 

Author(s): Yuichi Yoshida, Tatsushi Shiomi, Masahisa Shindo, Yoshiko Suyama, Bin Nakayama, Osamu Yamamoto

Journal: Acta Derm. Venereol.. 2012 Jan;92(1):109-10.

 

Last Updated: 5 Jan 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Microcystic adnexal carcinoma" returned 1 free, full-text review articles on human participants. First 3 results:

MRI of a microcystic adnexal carcinoma of the skin mimicking a fibrous tumour: case report and literature review.
 

Author(s): A M Tawfik, A Kreft, W Wagner, T J Vogl

Journal: Br J Radiol. 2011 Jun;84(1002):e114-7.

 

Microcystic adnexal carcinoma of the skin is a very rare malignant tumour arising from the sweat glands. As far as we know, the MRI features of this tumour have not been described in the literature before. In this report we present the MRI features and pathological description of ...

Last Updated: 24 May 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers
 

Status: Not yet recruiting

Condition Summary: Adenoid Cystic Carcinoma; Adnexal Carcinoma; Apocrine Carcinoma; Eccrine Porocarcinoma; Extraocular Cutaneous Sebaceous Carcinoma; Hidradenocarcinoma; Keratoacanthoma; Malignant Sweat Gland Neoplasm; Merkel Cell Carcinoma; Microcystic Adnexal Carcinoma; NK-Cell Lymphoma, Unclassifiable; Non-Melanomatous Lesion; Paget Disease; Papillary Adenocarcinoma; Primary Cutaneous Mucinous Carcinoma; Refractory Anaplastic Large Cell Lymphoma; Refractory Cutaneous T-Cell Non-Hodgkin Lymphoma; Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma; Refractory Mycosis Fungoides; Refractory T-Cell Non-Hodgkin Lymphoma; Sezary Syndrome; Signet Ring Cell Carcinoma; Skin Basal Cell Carcinoma; Skin Basosquamous Cell Carcinoma; Skin Squamous Cell Carcinoma; Spiradenocarcinoma; Squamous Cell Carcinoma of Unknown Primary Origin; Stage III Skin Cancer; Stage IV Skin Cancer; Sweat Gland Carcinoma; Trichilemmocarcinoma; Vulvar Squamous Cell Carcinoma

 

Last Updated: 8 Dec 2016

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