Membranous nephropathy

Common Name(s)

Membranous nephropathy

Membranous nephropathy is a kidney disease characterized by inflammation of the structures inside the kidney that help filter wastes and fluids. When the glomerular basement membrane becomes thickened, it does not work normally, allowing large amounts of protein to be lost in the urine. Symptoms develop gradually and may include swelling, fatigue, weight gain, and high blood pressure. In many cases, the underlying cause of membranous nephropathy is not known. Some cases are associated with other conditions (lupus), infections (hepatitis B and C), cancer or as a side effect of certain medications. The goal of treatment is to reduce symptoms and slow the progression of the disease.  
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Membranous nephropathy" for support, advocacy or research.

The NephCure Foundation

The NephCure Foundation is the only organization committed exclusively to support research seeking the cause of the potentially debilitating kidney disease Focal Segmental Glomerulosclerosis (FSGS) and Nephrotic Syndrome, improve treatment and find a cure.

Last Updated: 30 Jan 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Membranous nephropathy" for support, advocacy or research.

The NephCure Foundation

The NephCure Foundation is the only organization committed exclusively to support research seeking the cause of the potentially debilitating kidney disease Focal Segmental Glomerulosclerosis (FSGS) and Nephrotic Syndrome, improve treatment and find a cure.

http://www.nephcure.org

Last Updated: 30 Jan 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Membranous nephropathy" returned 366 free, full-text research articles on human participants. First 3 results:

Hypocomplementemic Urticarial Vasculitis Syndrome with Membranous Nephropathy: Case Report.
 

Author(s): Su Woong Jung, Yun Young Choi, In Seung Choi, Seulki Kim, Kyung Hwan Jeong, Ran Song, Sang Hoon Lee, Hyung In Yang, Seung Jae Hong, Yeon Ah Lee

Journal: J. Korean Med. Sci.. 2017 Dec;32(12):2064-2068.

 

Urticarial vasculitis is a rare disorder that principally manifests with recurrent urticarial, sometimes hemorrhagic, skin lesions and/or angioedema. Its clinical presentation is not always limited to cutaneous lesions and it can potentially affect other organs, such as the joints, ...

Last Updated: 31 Dec 1969

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Membranous nephropathy in a patient with ankylosing spondylitis: A case report.
 

Author(s): Ruiying Chen, Fang Li, Qionghong Xie, Jun Xue, Lingyun Lai, Shaojun Liu, Liyin Zhang, Chuanming Hao

Journal: Medicine (Baltimore). 2017 Oct;96(43):e8201.

 

Renal complications in ankylosing spondylitis (AS) were rarely observed, and proteinuria associated with AS can be seen often due to amyloidosis in this kind of complications, while membranous nephropathy (MN) is seldom considered. This article reports a case of coexistence of AS ...

Last Updated: 31 Dec 1969

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Comparative effectiveness and tolerance of immunosuppressive treatments for idiopathic membranous nephropathy: A network meta-analysis.
 

Author(s): Song Ren, Ying Wang, Li Xian, Tadashi Toyama, Meg Jardine, Guisen Li, Vlado Perkovic, Daqing Hong

Journal:

 

Immunosuppressive agents in general are shown to prevent renal progression and all-cause mortality in idiopathic membranous nephropathy (IMN) patients with nephrotic syndrome. However, the efficacy and safety of different immunosuppressive treatments have not been systematic assessed ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Membranous nephropathy" returned 48 free, full-text review articles on human participants. First 3 results:

The prognostic value of phospholipase A2 receptor autoantibodies on spontaneous remission for patients with idiopathic membranous nephropathy: A meta-analysis.
 

Author(s): Wenli Wu, Jin Shang, Chenyang Tao, Shuai Wang, Xiaoru Hu, Shiyi Zhang, Zhanzheng Zhao

Journal: Medicine (Baltimore). 2018 Jun;97(23):e11018.

 

The presence of antibodies against phospholipase A2 receptor (PLA2R-Abs) in serum at diagnosis is reported to be related to the rate of spontaneous remission in patients with idiopathic membranous nephropathy (IMN); however, there is still lack of enough samples to illustrate this ...

Last Updated: 31 Dec 1969

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Recent Progress in Deciphering the Etiopathogenesis of Primary Membranous Nephropathy.
 

Author(s): Andreas Kronbichler, Jun Oh, Björn Meijers, Gert Mayer, Jae Il Shin

Journal: Biomed Res Int. 2017 ;2017():1936372.

 

Primary membranous nephropathy (MN) is the leading cause of nephrotic syndrome in adults. Discovery of several antibodies has contributed to an increased understanding of MN. Antibodies against the M-type phospholipase A2 receptor (PLA2R) are present in 50-100% with primary MN and ...

Last Updated: 31 Dec 1969

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Primary Membranous Nephropathy.
 

Author(s): William G Couser

Journal: Clin J Am Soc Nephrol. 2017 Jun;12(6):983-997.

 

Membranous nephropathy (MN) is a unique glomerular lesion that is the most common cause of idiopathic nephrotic syndrome in nondiabetic white adults. About 80% of cases are renal limited (primary MN, PMN) and 20% are associated with other systemic diseases or exposures (secondary ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Adrenocorticotropic Hormone in Membranous Nephropathy
 

Status: Recruiting

Condition Summary: Membranous Nephropathy

 

Last Updated: 20 Mar 2018

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Peptide GAM Immunoadsorption Therapy in Autoimmune Membranous Nephropathy
 

Status: Recruiting

Condition Summary: Autoimmune Membranous Nephropathy

 

Last Updated: 16 Aug 2017

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Sequential Therapy With Tacrolimus and Rituximab in Primary Membranous Nephropathy
 

Status: Recruiting

Condition Summary: MEMBRANOUS NEPHROPATHY

 

Last Updated: 18 Aug 2016

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