Melorheostosis

Common Name(s)

Melorheostosis

Melorheostosis is a progressive skeletal disorder that causes bones to thicken. This condition can also affect joints, soft tissue, and skin. Melorheostosis can cause pain, stiffness, limited movement, and limb deformities, although some individuals do not have any symptoms. Mutations in the LEMD3 gene have been found to cause melorheostosis. Treatment options include surgery, physical and occupational therapy, hydrotherapy, and medications.
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Melorheostosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Melorheostosis" returned 15 free, full-text research articles on human participants. First 3 results:

Melorheostosis of the hand affecting the c6 sclerotome and presenting with carpal tunnel syndrome.
 

Author(s): Shalimar Abdullah, Noreen Fazlina Mat Nor, Nor Hazla Mohamed Haflah

Journal: Singapore Med J. 2014 Apr;55(4):e54-6.

 

Melorheostosis is a rare, progressive bone disease accompanied by hyperostosis and soft tissue fibrosis. While affected adults present with contracture and pain, children present with limb length discrepancy and deformity. We report the case of a 20-year-old woman with melorheostosis ...

Last Updated: 25 Apr 2014

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Bone scintigraphy elucidates different metabolic stages of melorheostosis.
 

Author(s): Sina Izadyar, Ali Gholamrezanezhad

Journal: Pan Afr Med J. 2012 ;11():21.

 

Melorheostosis is a rare benign non-hereditary sclerosing dysplasia involving the bone, often in a sclerotomal distribution. we report the case of a 27 years old lady with painful swelling of the left hand and forearm lasting for almost 15 years. The patient experienced aggravation ...

Last Updated: 19 Apr 2012

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[Melorheostosis, a case report].
 

Author(s): Tarek Carlos Salman Monte, Delfi Rotés Sala, Josep Blanch Rubió, Violeta Bittermann, Jordi Carbonell Abelló

Journal: Reumatol Clin. ;7(5):346-8.

 

Last Updated: 19 Sep 2011

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Melorheostosis" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.