Megacolon

Common Name(s)

Megacolon

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Megacolon" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Megacolon" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Megacolon" returned 107 free, full-text research articles on human participants. First 3 results:

Neurogenic Megacolon in Spinal Cord Injury.
 

Author(s): Rukma R Govindu, Michelle Kelley

Journal: N. Engl. J. Med.. 2016 12;375(22):e45.

 

Last Updated: 13 Dec 2016

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Last Updated: 23 Jul 2015

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Trypanosomiasis-induced megacolon illustrates how myenteric neurons modulate the risk for colon cancer in rats and humans.
 

Author(s): Vinicius Kannen, Enio C de Oliveira, Bruno Zene Motta, Annuar Jose Chaguri, Mariângela Ottoboni Brunaldi, Sérgio B Garcia

Journal:

 

Trypanosomiasis induces a remarkable myenteric neuronal degeneration leading to megacolon. Very little is known about the risk for colon cancer in chagasic megacolon patients. To clarify whether chagasic megacolon impacts on colon carcinogenesis, we investigated the risk for colon ...

Last Updated: 18 Apr 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Megacolon" returned 8 free, full-text review articles on human participants. First 3 results:

Chagasic megacolon: enteric neurons and related structures.
 

Author(s): Samir Jabari, Enio C de Oliveira, Axel Brehmer, Alexandre B M da Silveira

Journal: Histochem. Cell Biol.. 2014 Sep;142(3):235-44.

 

Megacolon, the irreversible dilation of a colonic segment, is a structural sign associated with various gastrointestinal disorders. In its hereditary, secondary form (e.g. in Hirschsprung's disease), dilation occurs in an originally healthy colonic segment due to an anally located, ...

Last Updated: 14 Aug 2014

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Toxic megacolon associated with cytomegalovirus infection in a patient with steroid-naïve ulcerative colitis.
 

Author(s): Ken Inoue, Naoki Wakabayashi, Kohei Fukumoto, Shinya Yamada, Nobukatsu Bito, Naohisa Yoshida, Kazuhiro Katada, Kazuhiko Uchiyama, Takeshi Ishikawa, Osamu Handa, Tomohisa Takagi, Hideyuki Konishi, Nobuaki Yagi, Satoshi Kokura, Mitsuo Kishimoto, Akio Yanagisawa, Yuji Naito

Journal: Intern. Med.. 2012 ;51(19):2739-43.

 

Most cases of cytomegalovirus (CMV) colitis in patients with inflammatory bowel disease (IBD) occur in those treated with immunosuppressants and/or corticosteroids. We herein present the case of a 57-year-old man with toxic megacolon associated with CMV colitis in corticosteroid-naïve ...

Last Updated: 5 Oct 2012

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Congenital aganglionic megacolon in Nigerian adults: two case reports and review of the literature.
 

Author(s): A A Bakari, B M Gali, A G Ibrahim, H A Nggada, N Ali, D Dogo, A M Abubakar

Journal: Niger J Clin Pract. ;14(2):249-52.

 

Congenital aganglionic mega colon (Hirschsprung's disease) is a motor disorder in the gut, due to a defect in the craniocaudal migration of the neuroblast originating from the neural crest that occurs during the first twelve weeks of gestation, causing a functional intestinal obstruction, ...

Last Updated: 23 Aug 2011

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Enhanced Recovery After Surgery In Hirschsprung Disease
 

Status: Recruiting

Condition Summary: Hirschsprung Disease

 

Last Updated: 18 May 2016

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Electrophysiological Activity of the Anorectum in Children Suspected of Hirschsprung Disease
 

Status: Not yet recruiting

Condition Summary: Hirschsprungs Disease

 

Last Updated: 20 Jan 2015

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Genetic Mosaicism in Hirschsprung's Disease
 

Status: Recruiting

Condition Summary: Hirschsprung Disease

 

Last Updated: 6 Apr 2017

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