Megacolon

Common Name(s)

Megacolon

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Megacolon" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Megacolon" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Megacolon" returned 77 free, full-text research articles on human participants. First 3 results:

Difficulties in the diagnostics and treatment of near-total congenital megacolon.
 

Author(s): L Topor, A Ulici, D Mălureanu, I Stoica, A Moga

Journal: Chirurgia (Bucur). ;109(5):701-4.

 

Near total colonic aganglionosis is one of the rarest forms of Hirschsprung's disease and until recent years it has been considered deadly. Establishing a correct diagnosis has proven to be challenging, because while the clinical and radiological features can be useful, they are not ...

Last Updated: 7 Nov 2014

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Blood vessels in ganglia in human esophagus might explain the higher frequency of megaesophagus compared with megacolon.
 

Author(s): Sheila Jorge Adad, Renata Margarida Etchebehere, Alessandro Adad Jammal

Journal: Rev. Inst. Med. Trop. Sao Paulo. ;56(6):529-32.

 

This study aimed to determine the existence of blood vessels within ganglia of the myenteric plexus of the human esophagus and colon. At necropsy, 15 stillborns, newborns and children up to two years of age, with no gastrointestinal disorders, were examined. Rings of the esophagus ...

Last Updated: 29 Oct 2014

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Could the complications of megacolon be avoided by monitoring the risk patients? cases report.
 

Author(s): A Toro, G Cappello, M Mannino, I Di Carlo

Journal: Chirurgia (Bucur). ;109(4):550-4.

 

We report 2 cases of megacolon associated with cerebrovascular accident and neuropsychiatric drug consumption. Case report 1: a 75-year-old woman with diabetes mellitus, hypertension, tachycardia with atrial fibrillation, bilateral pleural effusions and previous cerebral hemorrhage ...

Last Updated: 23 Aug 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Megacolon" returned 8 free, full-text review articles on human participants. First 3 results:

Chagasic megacolon: enteric neurons and related structures.
 

Author(s): Samir Jabari, Enio C de Oliveira, Axel Brehmer, Alexandre B M da Silveira

Journal: Histochem. Cell Biol.. 2014 Sep;142(3):235-44.

 

Megacolon, the irreversible dilation of a colonic segment, is a structural sign associated with various gastrointestinal disorders. In its hereditary, secondary form (e.g. in Hirschsprung's disease), dilation occurs in an originally healthy colonic segment due to an anally located, ...

Last Updated: 14 Aug 2014

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Toxic megacolon associated with cytomegalovirus infection in a patient with steroid-naïve ulcerative colitis.
 

Author(s): Ken Inoue, Naoki Wakabayashi, Kohei Fukumoto, Shinya Yamada, Nobukatsu Bito, Naohisa Yoshida, Kazuhiro Katada, Kazuhiko Uchiyama, Takeshi Ishikawa, Osamu Handa, Tomohisa Takagi, Hideyuki Konishi, Nobuaki Yagi, Satoshi Kokura, Mitsuo Kishimoto, Akio Yanagisawa, Yuji Naito

Journal: Intern. Med.. 2012 ;51(19):2739-43.

 

Most cases of cytomegalovirus (CMV) colitis in patients with inflammatory bowel disease (IBD) occur in those treated with immunosuppressants and/or corticosteroids. We herein present the case of a 57-year-old man with toxic megacolon associated with CMV colitis in corticosteroid-naïve ...

Last Updated: 5 Oct 2012

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Congenital aganglionic megacolon in Nigerian adults: two case reports and review of the literature.
 

Author(s): A A Bakari, B M Gali, A G Ibrahim, H A Nggada, N Ali, D Dogo, A M Abubakar

Journal: Niger J Clin Pract. ;14(2):249-52.

 

Congenital aganglionic mega colon (Hirschsprung's disease) is a motor disorder in the gut, due to a defect in the craniocaudal migration of the neuroblast originating from the neural crest that occurs during the first twelve weeks of gestation, causing a functional intestinal obstruction, ...

Last Updated: 23 Aug 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Trial on Treatments of Hirschsprung Allied Disease
 

Status: Recruiting

Condition Summary: Complications of Treatment; Complication of Surgical Procedure; Megacolon, Not Hirschsprung

 

Last Updated: 6 Aug 2014

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Fast-track Surgery in the Treatment of Hirschsprung's Disease
 

Status: Recruiting

Condition Summary: Surgery

 

Last Updated: 24 Jan 2015

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Electrophysiological Activity of the Anorectum in Children Suspected of Hirschsprung Disease
 

Status: Not yet recruiting

Condition Summary: Hirschsprungs Disease

 

Last Updated: 20 Jan 2015

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