Medullary sponge kidney

Common Name(s)

Medullary sponge kidney

Medullary sponge kidney (MSK) is a birth defect of the tubules-tiny tubes inside the kidneys. In a normal kidney, urine flows through these tubules as it is being formed. In MSK, tiny sacs called cysts form in the medulla-the inner part of the kidney-creating a sponge-like appearance. The cysts keep urine from flowing freely through the tubules. MSK is present at birth but symptoms typically do not occur until adulthood. Problems caused by MSK, include blood in the urine, kidney stones, and urinary tract infections. MSK rarely leads to more serious problems, such as total kidney failure.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Medullary sponge kidney" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Medullary sponge kidney" returned 16 free, full-text research articles on human participants. First 3 results:

CT urography for the diagnosis of medullary sponge kidney.
 

Author(s): Farrukh M Koraishy, Thuy-Trang T Ngo, Gary M Israel, Neera K Dahl

Journal: Am. J. Nephrol.. 2014 ;39(2):165-70.

 

Medullary sponge kidney (MSK) is characterized by malformation of the terminal collecting ducts and is associated with an increased risk of nephrolithiasis, nephrocalcinosis, urinary tract infections, renal acidification defects, and reduced bone density. It has been historically ...

Last Updated: 19 Mar 2014

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MR imaging of focal medullary sponge kidney: case report.
 

Author(s): Tomoyuki Hida, Akihiro Nishie, Yoshiki Asayama, Kousei Ishigami, Nobuhiro Fujita, Junichi Inokuchi, Seiji Naito, Sadamu Ando, Hiroshi Honda

Journal: Magn Reson Med Sci. 2012 ;11(1):65-9.

 

We present a case of focal medullary sponge kidney (MSK) that mimicked a renal tumor. Evaluation of a patient with history of macrohematuria revealed a left renal mass of 3-cm diameter. T(1)-weighted magnetic resonance (MR) images revealed a mass of mixed intensity protruding toward ...

Last Updated: 27 Mar 2012

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Long-term treatment with potassium citrate and renal stones in medullary sponge kidney.
 

Author(s): Antonia Fabris, Antonio Lupo, Patrizia Bernich, Cataldo Abaterusso, Nicola Marchionna, Antonio Nouvenne, Giovanni Gambaro

Journal: Clin J Am Soc Nephrol. 2010 Sep;5(9):1663-8.

 

Medullary sponge kidney (MSK) is a renal malformation typically associated with nephrocalcinosis and recurrent calcium stones. Incomplete distal renal tubular acidosis, hypocitraturia, and hypercalciuria are common. For stone prevention, patients with MSK generally receive the standard ...

Last Updated: 8 Sep 2010

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Medullary sponge kidney" returned 1 free, full-text review articles on human participants. First 3 results:

Medullary sponge kidney associated with congenital hemihypertrophy.
 

Author(s): O S Indridason, L Thomas, M Berkoben

Journal: J. Am. Soc. Nephrol.. 1996 Aug;7(8):1123-30.

 

Medullary sponge kidney is a developmental disorder characterized by ectatic and cystic malformation of the collecting ducts and tubules. Clinical manifestations include urinary tract infections, renal stones, and hematuria. It can be associated with other developmental disorders. ...

Last Updated: 28 Mar 1997

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Symptoms, Diagnosis, and Treatment

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