Meconium aspiration syndrome

Common Name(s)

Meconium aspiration syndrome

Meconium aspiration syndrome is a serious condition in which a newborn breathes a mixture of meconium and amniotic fluid into the lungs around the time of delivery. This can cause breathing difficulties due to swelling (inflammation) in the baby's lungs after birth. Treatment may include suctioning the newborn's mouth as soon as the head emerges during delivery, deep suctioning of the windpipe, antibiotics to treat infection, oxygen to keep blood levels normal, and radiant heat to maintain body temperature. In severe cases, the baby may need assistance breathing (ventilator).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Meconium aspiration syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Meconium aspiration syndrome" returned 18 free, full-text research articles on human participants. First 3 results:

[Clinical effect of endotracheal lavage with porcine pulmonary surfactant in term neonates with severe meconium aspiration syndrome].
 

Author(s): Xin-Zhu Lin, Ji-Dong Lai, Zhao-Yang Lan, Ya-Yin Lin

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2014 Jul;16(7):709-13.

 

To evaluate the clinical effect of endotracheal lavage with porcine pulmonary surfactant (PS) in term neonates with severe meconium aspiration syndrome (MAS).

Last Updated: 10 Jul 2014

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[Efficacy of pulmonary surfactant therapy in neonates with meconium aspiration syndrome: a meta-analysis].
 

Author(s): Fei-Fei Luo, Di-Yuan Yang, Pan Chen, Zi-Yu Hua

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2012 Jun;14(6):413-7.

 

The efficacy of pulmonary surfactant (PS) replacement therapy for meconium aspiration syndrome (MAS) remains controversial. This study aimed to evaluate the efficacy of PS therapy in neonates with MAS by a meta-analysis.

Last Updated: 28 Jun 2012

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Management of meconium aspiration syndrome with highfrequency oscillatory ventilation.
 

Author(s): Asma Bouziri, Asma Hamdi, Ammar Khaldi, Sarra Bel Hadj, Khaled Menif, Nejla Ben Jaballah

Journal: Tunis Med. 2011 Jul;89(7):632-7.

 

High-frequency oscillatory ventilation (HFOV) has been advocated for use to improve lung inflation while potentially decreasing lung injury. There were few data on the early use of HFOV in hypoxemic term neonates.

Last Updated: 22 Jul 2011

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Meconium aspiration syndrome" returned 4 free, full-text review articles on human participants. First 3 results:

Surfactant lavage therapy for meconium aspiration syndrome: a systematic review and meta-analysis.
 

Author(s): Hyun Jin Choi, Seokyung Hahn, Joongyub Lee, Byung-Joo Park, Soon Min Lee, Han-Suk Kim, Chong-Woo Bae

Journal: Neonatology. 2012 ;101(3):183-91.

 

Lung lavage with diluted surfactant has emerged as an innovative treatment for meconium aspiration syndrome (MAS). However, the treatment effect has not yet been fully established.

Last Updated: 23 Mar 2012

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Meconium aspiration syndrome: do we know?
 

Author(s): Murat Yurdakök

Journal: Turk. J. Pediatr.. ;53(2):121-9.

 

Meconium is a common finding in amniotic fluid and placental specimens, particularly in the term or post-term pregnancy. The most important consequence of meconium-stained amniotic fluid (MSAF) is meconium aspiration syndrome (MAS), and at least 5% of infants born through MSAF develop ...

Last Updated: 22 Aug 2011

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Glucocorticoids in the treatment of neonatal meconium aspiration syndrome.
 

Author(s): Daniela Mokra, Juraj Mokry

Journal: Eur. J. Pediatr.. 2011 Dec;170(12):1495-505.

 

Meconium aspiration syndrome is a serious neonatal disease with complex pathophysiology. With respect to the contribution of meconium-induced lung edema, inflammation and vasoconstriction on the course of the disease, glucocorticoids are increasingly used in the treatment of MAS despite ...

Last Updated: 22 Nov 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Surfactant Lavage vs. Bolus Surfactant in Neonates With Meconium Aspiration
 

Status: Recruiting

Condition Summary: Meconium Aspiration Syndrome

 

Last Updated: 16 Oct 2006

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Lung Lavage With Dilute Poractant Alfa for Meconium Aspiration Syndrome
 

Status: Recruiting

Condition Summary: Meconium Aspiration Syndrome

 

Last Updated: 17 Jan 2014

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Efficacy and Safety of Gastric Suctioning During Neonatal Resuscitation
 

Status: Not yet recruiting

Condition Summary: Respiratory Distress

 

Last Updated: 7 Aug 2008

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