Meconium aspiration syndrome

Common Name(s)

Meconium aspiration syndrome

Meconium aspiration syndrome is a serious condition in which a newborn breathes a mixture of meconium and amniotic fluid into the lungs around the time of delivery. This can cause breathing difficulties due to swelling (inflammation) in the baby's lungs after birth. Treatment may include suctioning the newborn's mouth as soon as the head emerges during delivery, deep suctioning of the windpipe, antibiotics to treat infection, oxygen to keep blood levels normal, and radiant heat to maintain body temperature. In severe cases, the baby may need assistance breathing (ventilator).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Meconium aspiration syndrome" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Meconium aspiration syndrome" returned 24 free, full-text research articles on human participants. First 3 results:

Controlled hypothermia may improve surfactant function in asphyxiated neonates with or without meconium aspiration syndrome.
 

Author(s): Chiara Autilio, Mercedes Echaide, Daniele De Luca, Jesús Pérez-Gil

Journal:

 

Whole-body hypothermia (WBH) is used to improve neurological outcomes in perinatal asphyxia. Recent studies suggested a beneficial effect of hypothermia for some types of acute respiratory failure. However, no data are available about the biophysical function of human surfactant during ...

Last Updated: 31 Dec 1969

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Detrimental Complications Of Meconium Aspiration Syndrome And Their Impact On Outcome.
 

Author(s): Mehmood Shaikh, Khawaja Ahmad Irfan Waheed, Sulman Javaid, Rafia Gul, Muhammad Almas Hashmi, Syeda Tehseen Fatima

Journal: J Ayub Med Coll Abbottabad. ;28(3):506-509.

 

Meconium aspiration syndrome (MAS) is respiratory distress in an infant born through meconium stained amniotic fluid (MSAF) whose signs cannot be otherwise explained. MAS is associated with different complications. Many studies have been conducted in developed world to find the outcome ...

Last Updated: 31 Dec 1969

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Lung ultrasonography to diagnose meconium aspiration syndrome of the newborn.
 

Author(s): Jing Liu, Hai-Ying Cao, Wei Fu

Journal: J. Int. Med. Res.. 2016 Dec;44(6):1534-1542.

 

Objective To investigate the diagnostic value of lung ultrasonography for neonatal meconium aspiration syndrome (MAS). Methods This prospective observational study enrolled patients diagnosed with MAS based on medical history, clinical manifestations and chest X-ray and control newborns ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Meconium aspiration syndrome" returned 4 free, full-text review articles on human participants. First 3 results:

Surfactant therapy and antibiotics in neonates with meconium aspiration syndrome: a systematic review and meta-analysis.
 

Author(s): C K Natarajan, M J Sankar, K Jain, R Agarwal, V K Paul

Journal: J Perinatol. 2016 May;36 Suppl 1():S49-54.

 

Meconium aspiration syndrome (MAS), a common cause of respiratory failure in neonates, is associated with high mortality and morbidity. The objectives of this review were to evaluate the effects of administration of (a) surfactant-either as lung lavage (SLL) or bolus surfactant (BS) ...

Last Updated: 31 Dec 1969

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Meconium aspiration syndrome: possible pathophysiological mechanisms and future potential therapies.
 

Author(s): Paal Helge Haakonsen Lindenskov, Albert Castellheim, Ola Didrik Saugstad, Tom Eirik Mollnes

Journal: Neonatology. 2015 ;107(3):225-30.

 

Does meconium cause meconium aspiration syndrome (MAS) or is meconium discharge only a marker of fetal hypoxia? This dispute has lasted for centuries, but since the 1960s, detrimental effects of meconium itself on the lungs have been demonstrated in animal experiments. In clinical ...

Last Updated: 31 Dec 1969

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Surfactant lavage therapy for meconium aspiration syndrome: a systematic review and meta-analysis.
 

Author(s): Hyun Jin Choi, Seokyung Hahn, Joongyub Lee, Byung-Joo Park, Soon Min Lee, Han-Suk Kim, Chong-Woo Bae

Journal: Neonatology. 2012 ;101(3):183-91.

 

Lung lavage with diluted surfactant has emerged as an innovative treatment for meconium aspiration syndrome (MAS). However, the treatment effect has not yet been fully established.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Meconium Aspiration and Tracheal Suctioning—Feasibility Study
 

Status: Not yet recruiting

Condition Summary: Meconium Aspiration Syndrome

 

Last Updated: 13 Feb 2018

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Pulmonary Function Using Non-invasive Forced Oscillometry
 

Status: Recruiting

Condition Summary: Infant, Premature, Diseases; Infant, Newborn, Diseases; Bronchopulmonary Dysplasia; Respiratory Distress Syndrome, Newborn; Meconium Aspiration Syndrome; Transient Tachypnea of the Newborn

 

Last Updated: 6 Dec 2017

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