Malignant hyperthermia susceptibility type 1

Common Name(s)

Malignant hyperthermia susceptibility type 1

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Malignant hyperthermia susceptibility type 1" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Malignant hyperthermia susceptibility type 1" returned 2 free, full-text research articles on human participants. First 3 results:

Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor.
 

Author(s): Jose Miguel Eltit, Roger A Bannister, Ong Moua, Francisco Altamirano, Philip M Hopkins, Isaac N Pessah, Tadeusz F Molinski, Jose R López, Kurt G Beam, Paul D Allen

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2012 May;109(20):7923-8.

 

Malignant hyperthermia (MH) susceptibility is a dominantly inherited disorder in which volatile anesthetics trigger aberrant Ca(2+) release in skeletal muscle and a potentially fatal rise in perioperative body temperature. Mutations causing MH susceptibility have been identified in ...

Last Updated: 16 May 2012

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Malignant-hyperthermia susceptibility is associated with a mutation of the alpha 1-subunit of the human dihydropyridine-sensitive L-type voltage-dependent calcium-channel receptor in skeletal muscle.
 

Author(s): N Monnier, V Procaccio, P Stieglitz, J Lunardi

Journal: Am. J. Hum. Genet.. 1997 Jun;60(6):1316-25.

 

Malignant hyperthermia susceptibility (MHS) is characterized by genetic heterogeneity. However, except for the MHS1 locus, which corresponds to the skeletal muscle ryanodine receptor (RYR1) and for which several mutations have been described, no direct molecular evidence for a mutation ...

Last Updated: 10 Jul 1997

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Malignant hyperthermia susceptibility type 1" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

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