Malignant fibrous histiocytoma

Common Name(s)

Malignant fibrous histiocytoma

Malignant fibrous histiocytoma is a rare form of cancer characterized by abnormal cell growth in the fibrous support tissue or the bone. Individuals with this disorder may grow harmful tumors in the muscles and bone that can spread to the rest of the body if not diagnosed and treated early. The abnormal cell growth usually develops in the extremities (toes, fingers etc.), but can also form anywhere in the body. This form of cancer can thus cause individuals to be less capable of performing important movements, like walking and running. Some individuals may loss their ability to move certain parts of their body (paralysis). Common symptoms include weight loss, abdominal pain and breathing problems. Diagnosis may require blood tests and imaging studies such as a CT scan. A physician may also need to take a biopsy, which is where they surgically remove a small portion of the tumor to look at under a microscope. Treatment is developed on a case-by-case basis and may include a combination of chemotherapy, radiation, and surgery.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Malignant fibrous histiocytoma" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Malignant fibrous histiocytoma" returned 193 free, full-text research articles on human participants. First 3 results:

Malignant fibrous histiocytoma in a patient presenting with urinary system symptoms.
 

Author(s): Mustafa Resorlu, Ozan Karatag, Fatma Uysal, Muhsin Ozturk

Journal: Rev Assoc Med Bras (1992). 2017 Nov;63(11):950-952.

 

Malignant fibrous histiocytoma is a rare tumor. It is most commonly seen in individuals between the fifth and seventh decades of life, in extremities, and less frequently in the retroperitoneum. Although its etiology is not clearly known, radiotherapy, chemical agents, previous history ...

Last Updated: 31 Dec 1969

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En bloc resection and prosthesis implantation to treat malignant fibrous histiocytoma of the humerus.
 

Author(s): Jun Sun, Ru-Ming Zhang, Yu-Xin Zheng

Journal: Adv Clin Exp Med. 2017 Aug;26(5):781-787.

 

Malignant fibrous histiocytoma (MFH) of the bone is a rare tumor. Most studies comparing limb salvage and amputation have reported that limb salvage had no adverse effect on the long-term survival of patients. This study evaluates the oncological outcomes of limb salvage procedures ...

Last Updated: 31 Dec 1969

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Malignant fibrous histiocytoma arising from renal capsule: An extremely rare entity.
 

Author(s): Shilpa Bairwa, Ashok Sangwaiya, Mariyam Ansari, Arpita Jindal, Sapna Singla, Ajay Yadav

Journal: Indian J Pathol Microbiol. ;60(3):402-404.

 

Malignant fibrous histiocytoma (MFH) usually presents in the extremities or retroperitoneum. MFH arising from renal parenchyma or renal capsule is extremely rare, only few cases have been reported in literature and portend a poor prognosis. Renal MFH is differentiated from renal cell ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Malignant fibrous histiocytoma" returned 24 free, full-text review articles on human participants. First 3 results:

Primary hepatic malignant fibrous histiocytoma combined with invasion of inferior vena cava: A case report and literature review.
 

Author(s): Yifan Tong, Hong Yu, Bo Shen, Xu Feng, Guanglan Wang, Xiujun Cai

Journal: Medicine (Baltimore). 2017 Jun;96(23):e7110.

 

Malignant fibrous histiocytoma (MFH), primary presented in liver, was very rare and displayed a poor prognosis because of high aggression. As a few of cases had been reported merely, we shared the case of primary hepatic MFH combined with invasion of inferior vena cava (IVC).

Last Updated: 31 Dec 1969

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Unusual localization of a primary pleomorphic malignant fibrous histiocytoma on the mitral valve: a case report and review of the literature.
 

Author(s): Edvin Prifti, Fadil Ademaj, Majlinda Ikonomi, Aurel Demiraj

Journal:

 

It has been reported that cardiac malignant fibrous histiocytomas occur more frequently in the left side of the heart, especially in the left atrium, but rarely invade the mitral valve. We present a case with a giant malignant fibrous histiocytoma with an unusual localization involving ...

Last Updated: 31 Dec 1969

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Diagnostic and therapeutic strategy and the most efficient prognostic factors of breast malignant fibrous histiocytoma.
 

Author(s): Si-Qi Qiu, Xiao-Long Wei, Wen-He Huang, Ming-Yao Wu, Yun-Sheng Qin, Yang-Kang Li, Guo-Jun Zhang

Journal: Sci Rep. 2013 ;3():2529.

 

We analyzed the clinicopathological features of 9 breast malignant fibrous histiocytoma (MFH) patients. Immunohistochemistry was used to make both diagnosis and differential diagnosis, and to identify prognostic factors. All tumors lacked epithelial markers but expressed mesenchymal ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 2 Jul 2018

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Last Updated: 8 Dec 2017

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Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma
 

Status: Recruiting

Condition Summary: Undifferentiated Pleomorphic Sarcoma; Liposarcoma; Chondrosarcoma; Osteosarcoma; Ewing Sarcoma

 

Last Updated: 24 Aug 2017

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