Malignant fibrous histiocytoma

Common Name(s)

Malignant fibrous histiocytoma

Malignant fibrous histiocytoma is a rare form of cancer characterized by abnormal cell growth in the fibrous support tissue or the bone. Individuals with this disorder may grow harmful tumors in the muscles and bone that can spread to the rest of the body if not diagnosed and treated early. The abnormal cell growth usually develops in the extremities (toes, fingers etc.), but can also form anywhere in the body. This form of cancer can thus cause individuals to be less capable of performing important movements, like walking and running. Some individuals may loss their ability to move certain parts of their body (paralysis). Common symptoms include weight loss, abdominal pain and breathing problems. Diagnosis may require blood tests and imaging studies such as a CT scan. A physician may also need to take a biopsy, which is where they surgically remove a small portion of the tumor to look at under a microscope. Treatment is developed on a case-by-case basis and may include a combination of chemotherapy, radiation, and surgery.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Malignant fibrous histiocytoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Malignant fibrous histiocytoma" returned 265 free, full-text research articles on human participants. First 3 results:

Primary malignant fibrous histiocytoma of long bones: long-term follow-up.
 

Author(s): Bülent Özkurt, Kerem Başarır, Yusuf H Yıldız, Mahmut Kalem, Yener Sağlık

Journal: Eklem Hastalik Cerrahisi. 2016 Aug;27(2):94-9.

 

This study aims to evaluate patients diagnosed with malignant fibrous histiocytoma and investigate the possible prognostic factors associated with duration of survival.

Last Updated: 8 Aug 2016

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Intrascrotal paratesticular malignant fibrous histiocytoma-a rare case and its management.
 

Author(s): A A Kallianpur, A Kapali, N K Shukla, S V S Deo, D Muduly, R Yadav

Journal: Indian J Cancer. ;52(4):688-9.

 

Last Updated: 10 Mar 2016

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A rare case of carcinosarcoma of breast: Coexistence of mucinous carcinoma and malignant fibrous histiocytoma.
 

Author(s): Min Liu, Bailong Liu, Yanqiu Song, Lihua Dong

Journal: J Cancer Res Ther. ;11(4):1024.

 

Carcinosarcoma (CS) of breast is a rare disease. Published reports provided little consensus about its clinical characteristics and optimal treatment protocols. Here we present a patient with CS of breast (mucinous carcinoma and malignant fibrous histiocytoma) and review related literature. ...

Last Updated: 17 Feb 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Malignant fibrous histiocytoma" returned 30 free, full-text review articles on human participants. First 3 results:

Primary hepatic malignant fibrous histiocytoma combined with invasion of inferior vena cava: A case report and literature review.
 

Author(s): Yifan Tong, Hong Yu, Bo Shen, Xu Feng, Guanglan Wang, Xiujun Cai

Journal: Medicine (Baltimore). 2017 Jun;96(23):e7110.

 

Malignant fibrous histiocytoma (MFH), primary presented in liver, was very rare and displayed a poor prognosis because of high aggression. As a few of cases had been reported merely, we shared the case of primary hepatic MFH combined with invasion of inferior vena cava (IVC).

Last Updated: 7 Jun 2017

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Unusual localization of a primary pleomorphic malignant fibrous histiocytoma on the mitral valve: a case report and review of the literature.
 

Author(s): Edvin Prifti, Fadil Ademaj, Majlinda Ikonomi, Aurel Demiraj

Journal:

 

It has been reported that cardiac malignant fibrous histiocytomas occur more frequently in the left side of the heart, especially in the left atrium, but rarely invade the mitral valve. We present a case with a giant malignant fibrous histiocytoma with an unusual localization involving ...

Last Updated: 31 Oct 2015

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Diagnostic and therapeutic strategy and the most efficient prognostic factors of breast malignant fibrous histiocytoma.
 

Author(s): Si-Qi Qiu, Xiao-Long Wei, Wen-He Huang, Ming-Yao Wu, Yun-Sheng Qin, Yang-Kang Li, Guo-Jun Zhang

Journal: Sci Rep. 2013 ;3():2529.

 

We analyzed the clinicopathological features of 9 breast malignant fibrous histiocytoma (MFH) patients. Immunohistochemistry was used to make both diagnosis and differential diagnosis, and to identify prognostic factors. All tumors lacked epithelial markers but expressed mesenchymal ...

Last Updated: 28 Aug 2013

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 5 Oct 2017

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Last Updated: 18 Apr 2017

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Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma
 

Status: Recruiting

Condition Summary: Undifferentiated Pleomorphic Sarcoma; Liposarcoma; Chondrosarcoma; Osteosarcoma; Ewing Sarcoma

 

Last Updated: 24 Aug 2017

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