Malaria

Common Name(s)

Malaria

Malaria is a serious and sometimes fatal disease caused by a parasite that commonly infects a certain type of mosquito which feeds on humans. Infection with malaria parasites may result in a wide variety of symptoms, ranging from absent or very mild symptoms to severe disease and even death. People who get malaria are typically very sick with high fevers, shaking chills, and flu-like illness. In general, malaria is a curable disease if diagnosed and treated promptly and correctly. Treatment depends on many factors including disease severity, the species of malaria parasite causing the infection and the part of the world in which the infection was acquired.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Malaria" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Malaria" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Malaria" returned 8051 free, full-text research articles on human participants. First 3 results:

Experimental study of the relationship between Plasmodium gametocyte density and infection success in mosquitoes; implications for the evaluation of malaria transmission-reducing interventions.
 

Author(s): Dari F Da, Thomas S Churcher, Rakiswendé S Yerbanga, Bienvenue Yaméogo, Ibrahim Sangaré, Jean Bosco Ouedraogo, Robert E Sinden, Andrew M Blagborough, Anna Cohuet

Journal: Exp. Parasitol.. 2015 Feb;149():74-83.

 

The evaluation of transmission reducing interventions (TRI) to control malaria widely uses membrane feeding assays. In such assays, the intensity of Plasmodium infection in the vector might affect the measured efficacy of the candidates to block transmission. Gametocyte density in ...

Last Updated: 2 Feb 2015

Go To URL
Gut microbiota elicits a protective immune response against malaria transmission.
 

Author(s): Bahtiyar Yilmaz, Silvia Portugal, Tuan M Tran, Raffaella Gozzelino, Susana Ramos, Joana Gomes, Ana Regalado, Peter J Cowan, Anthony J F d'Apice, Anita S Chong, Ogobara K Doumbo, Boubacar Traore, Peter D Crompton, Henrique Silveira, Miguel P Soares

Journal: Cell. 2014 Dec;159(6):1277-89.

 

Glycosylation processes are under high natural selection pressure, presumably because these can modulate resistance to infection. Here, we asked whether inactivation of the UDP-galactose:β-galactoside-α1-3-galactosyltransferase (α1,3GT) gene, which ablated the expression of the ...

Last Updated: 6 Dec 2014

Go To URL
Malaria surveillance--United States, 2012.
 

Author(s): Karen A Cullen, Paul M Arguin,

Journal: MMWR Surveill Summ. 2014 Dec;63(12):1-22.

 

Malaria in humans is caused by intraerythrocytic protozoa of the genus Plasmodium. These parasites are transmitted by the bite of an infective female Anopheles mosquito. The majority of malaria infections in the United States occur among persons who have traveled to regions with ongoing ...

Last Updated: 5 Dec 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Malaria" returned 785 free, full-text review articles on human participants. First 3 results:

Fatal cerebral malaria: a venous efflux problem.
 

Author(s): Ute Frevert, Adéla Nacer

Journal:

 

Most Plasmodium falciparum-infected children with cerebral malaria (CM) die from respiratory arrest, but the underlying pathology is unclear. Here we present a model in which the ultimate cause of death from CM is severe intracranial hypertension. Dynamic imaging of mice infected ...

Last Updated: 21 Nov 2014

Go To URL
Malaria and hypertension. Another co-evolutionary adaptation?
 

Author(s): Julio Gallego-Delgado, Ana Rodriguez

Journal:

 

Last Updated: 18 Sep 2014

Go To URL
Cerebral malaria: gamma-interferon redux.
 

Author(s): Nicholas H Hunt, Helen J Ball, Anna M Hansen, Loke T Khaw, Jintao Guo, Supun Bakmiwewa, Andrew J Mitchell, Valéry Combes, Georges E R Grau

Journal:

 

There are two theories that seek to explain the pathogenesis of cerebral malaria, the mechanical obstruction hypothesis and the immunopathology hypothesis. Evidence consistent with both ideas has accumulated from studies of the human disease and experimental models. Thus, some combination ...

Last Updated: 1 Sep 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Mass Drug Administration With Dihydroartemisinin + Piperaquine for Reducing Malaria in Southern Zambia
 

Status: Recruiting

Condition Summary: Malaria; Malaria, Falciparum

 

Last Updated: 30 Dec 2014

Go to URL
Malaria in Early Life Study
 

Status: Recruiting

Condition Summary: Plasmodium Falciparum Malaria; Plasmodium Vivax Malaria

 

Last Updated: 31 May 2014

Go to URL
Randomized Trial of Erythropoietin During Cerebral Malaria
 

Status: Recruiting

Condition Summary: Cerebral Malaria

 

Last Updated: 12 Jun 2008

Go to URL