Malaria

Common Name(s)

Malaria

Malaria is a serious and sometimes fatal disease caused by a parasite that commonly infects a certain type of mosquito which feeds on humans. Infection with malaria parasites may result in a wide variety of symptoms, ranging from absent or very mild symptoms to severe disease and even death. People who get malaria are typically very sick with high fevers, shaking chills, and flu-like illness. In general, malaria is a curable disease if diagnosed and treated promptly and correctly. Treatment depends on many factors including disease severity, the species of malaria parasite causing the infection and the part of the world in which the infection was acquired.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Malaria" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Malaria" returned 8009 free, full-text research articles on human participants. First 3 results:

Gut microbiota elicits a protective immune response against malaria transmission.
 

Author(s): Bahtiyar Yilmaz, Silvia Portugal, Tuan M Tran, Raffaella Gozzelino, Susana Ramos, Joana Gomes, Ana Regalado, Peter J Cowan, Anthony J F d'Apice, Anita S Chong, Ogobara K Doumbo, Boubacar Traore, Peter D Crompton, Henrique Silveira, Miguel P Soares

Journal: Cell. 2014 Dec;159(6):1277-89.

 

Glycosylation processes are under high natural selection pressure, presumably because these can modulate resistance to infection. Here, we asked whether inactivation of the UDP-galactose:β-galactoside-α1-3-galactosyltransferase (α1,3GT) gene, which ablated the expression of the ...

Last Updated: 6 Dec 2014

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Malaria surveillance--United States, 2012.
 

Author(s): Karen A Cullen, Paul M Arguin,

Journal: MMWR Surveill Summ. 2014 Dec;63(12):1-22.

 

Malaria in humans is caused by intraerythrocytic protozoa of the genus Plasmodium. These parasites are transmitted by the bite of an infective female Anopheles mosquito. The majority of malaria infections in the United States occur among persons who have traveled to regions with ongoing ...

Last Updated: 5 Dec 2014

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Malaria parasites prepare for flight.
 

Author(s): Sarah E Reece, Nicole Mideo

Journal: Trends Parasitol.. 2014 Dec;30(12):551-3.

 

Life in seasonal environments often means facing extreme environmental fluctuations. Many multicellular organisms have evolved strategies to cope with this lifestyle. Single-celled malaria parasites are no different. An elegant experiment reveals that they respond to the availability ...

Last Updated: 18 Dec 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Malaria" returned 768 free, full-text review articles on human participants. First 3 results:

Fatal cerebral malaria: a venous efflux problem.
 

Author(s): Ute Frevert, Adéla Nacer

Journal:

 

Most Plasmodium falciparum-infected children with cerebral malaria (CM) die from respiratory arrest, but the underlying pathology is unclear. Here we present a model in which the ultimate cause of death from CM is severe intracranial hypertension. Dynamic imaging of mice infected ...

Last Updated: 21 Nov 2014

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Malaria and hypertension. Another co-evolutionary adaptation?
 

Author(s): Julio Gallego-Delgado, Ana Rodriguez

Journal:

 

Last Updated: 18 Sep 2014

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Malaria in school-age children in Africa: an increasingly important challenge.
 

Author(s): Joaniter Nankabirwa, Simon J Brooker, Sian E Clarke, Deepika Fernando, Caroline W Gitonga, David Schellenberg, Brian Greenwood

Journal: Trop. Med. Int. Health. 2014 Nov;19(11):1294-309.

 

School-age children have attracted relatively little attention as a group in need of special measures to protect them against malaria. However, increasing success in lowering the level of malaria transmission in many previously highly endemic areas will result in children acquiring ...

Last Updated: 8 Oct 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Mass Drug Administration With Dihydroartemisinin + Piperaquine for Reducing Malaria in Southern Zambia
 

Status: Recruiting

Condition Summary: Malaria; Malaria, Falciparum

 

Last Updated: 30 Dec 2014

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Malaria in Early Life Study
 

Status: Recruiting

Condition Summary: Plasmodium Falciparum Malaria; Plasmodium Vivax Malaria

 

Last Updated: 31 May 2014

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Randomized Trial of Erythropoietin During Cerebral Malaria
 

Status: Recruiting

Condition Summary: Cerebral Malaria

 

Last Updated: 12 Jun 2008

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