Malaria

Common Name(s)

Malaria

Malaria is a serious and sometimes fatal disease caused by a parasite that commonly infects a certain type of mosquito which feeds on humans. Infection with malaria parasites may result in a wide variety of symptoms, ranging from absent or very mild symptoms to severe disease and even death. People who get malaria are typically very sick with high fevers, shaking chills, and flu-like illness. In general, malaria is a curable disease if diagnosed and treated promptly and correctly. Treatment depends on many factors including disease severity, the species of malaria parasite causing the infection and the part of the world in which the infection was acquired.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Malaria" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Malaria" returned 7499 free, full-text research articles on human participants. First 3 results:

Parasite burden and severity of malaria in Tanzanian children.
 

Author(s): Bronner P Gonçalves, Chiung-Yu Huang, Robert Morrison, Sarah Holte, Edward Kabyemela, D Rebecca Prevots, Michal Fried, Patrick E Duffy

Journal: N. Engl. J. Med.. 2014 May;370(19):1799-808.

 

Severe Plasmodium falciparum malaria is a major cause of death in children. The contribution of the parasite burden to the pathogenesis of severe malaria has been controversial.

Last Updated: 8 May 2014

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Kinetics of B cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites.
 

Author(s): Paulina Ampomah, Liz Stevenson, Michael F Ofori, Lea Barfod, Lars Hviid

Journal: J. Immunol.. 2014 Jun;192(11):5236-44.

 

Naturally acquired protective immunity to Plasmodium falciparum malaria takes years to develop. It relies mainly on Abs, particularly IgG specific for Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) proteins on the infected erythrocyte surface. It is only partially understood ...

Last Updated: 19 May 2014

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Glycophorin C (CD236R) mediates vivax malaria parasite rosetting to normocytes.
 

Author(s): Wenn-Chyau Lee, Benoit Malleret, Yee-Ling Lau, Marjorie Mauduit, Mun-Yik Fong, Jee Sun Cho, Rossarin Suwanarusk, Rou Zhang, Letusa Albrecht, Fabio T M Costa, Peter Preiser, Rose McGready, Laurent Renia, Francois Nosten, Bruce Russell

Journal: Blood. 2014 May;123(18):e100-9.

 

Rosetting phenomenon has been linked to malaria pathogenesis. Although rosetting occurs in all causes of human malaria, most data on this subject has been derived from Plasmodium falciparum. Here, we investigate the function and factors affecting rosette formation in Plasmodium vivax. ...

Last Updated: 5 May 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Malaria" returned 709 free, full-text review articles on human participants. First 3 results:

Malaria elimination: needs assessment and priorities for the future.
 

Author(s): Amal El-Moamly

Journal:

 

When the World Health Organization announced the goal of global eradication of malaria in 2007, questions were raised about the naivety of this proposition. Since then, experts have been divided about this goal. Some scientists suggest that when defeating malaria, elimination is a ...

Last Updated: 18 Nov 2013

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N-terminal Plasmodium vivax merozoite surface protein-1, a potential subunit for malaria vivax vaccine.
 

Author(s): Fernanda G Versiani, Maria E Almeida, Luis A Mariuba, Patricia P Orlandi, Paulo A Nogueira

Journal: Clin. Dev. Immunol.. 2013 ;2013():965841.

 

The human malaria is widely distributed in the Middle East, Asia, the western Pacific, and Central and South America. Plasmodium vivax started to have the attention of many researchers since it is causing diseases to millions of people and several reports of severe malaria cases have ...

Last Updated: 4 Nov 2013

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Malaria vaccine research and development: the role of the WHO MALVAC committee.
 

Author(s): Geoffrey A T Targett, Vasee S Moorthy, Graham V Brown

Journal:

 

The WHO Malaria Vaccine Advisory Committee (MALVAC) provides advice to WHO on strategic priorities, activities and technical issues related to global efforts to develop vaccines against malaria. MALVAC convened a series of meetings to obtain expert, impartial consensus views on the ...

Last Updated: 15 Nov 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Malaria in Early Life Study
 

Status: Recruiting

Condition Summary: Plasmodium Falciparum Malaria; Plasmodium Vivax Malaria

 

Last Updated: 31 May 2014

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Community-based Scheduled Screening and Treatment of Malaria in Pregnancy for Improved Maternal and Infant Health: a Cluster-randomized Trial in The Gambia, Burkina Faso and Benin
 

Status: Not yet recruiting

Condition Summary: Malaria, Antepartum; Maternal Malaria During Pregnancy - Baby Not Yet Delivered; Small for Gestational Age (Disorder)

 

Last Updated: 10 Sep 2013

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