Anemia

Common Name(s)

Anemia, Anemias

Anemia occurs when there is a decreased amount of hemoglobin, an iron-rich protein inside red blood cells, that helps carry oxygen throughout the body. Symptoms include general weakness, tiredness, difficulty concentrating, shortness of breath, confusion, dizziness, headaches, brittle nails, pale skin, and lightheadedness. Severe anemia, when it goes untreated, can cause heart and other organ failures, and in rare and extreme cases, even death. Although there are many types of anemia, anemias are categorized into three main groups: anemia caused by blood loss, anemia caused by decreased red blood cell production, and anemia caused by the destruction of red blood cells. Anemia through blood loss is usually caused from gastrointestinal bleeding such as ulcers or hemorrhoids, but can also occur from surgery or frequent blood donations. Anemia is also more commonly in females than in males due to menstruation and pregnancy. Anemia due to a lack of red blood cell production or increased red blood cell destruction can be due to abnormal red blood cells or various other conditions or factors including sickle cell anemia, iron and other vitamin deficiencies, poor dieting, bone marrow conditions, organ irregularities, infections, and toxins.

Anemia can be diagnosed through a physical examination and a simple blood test, although diagnosing the type of anemia may require more tests. Treatments vary depending on the severity and kind of the anemia including proper dieting, iron, and vitamin supplements. If the anemia is severe other treatments, including blood transfusions or medications, may be needed. If you or a family member has been diagnosed with anemia, talk to your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anemia" for support, advocacy or research.

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Mucolipidosis Type IV (ML4) Foundation

The mission of the Foundation is to fund, promote and support scientific research dedicated to developing treatments and a cure for ML4 by providing critical financial support to researchers; linking individuals with ML4 to researchers for clinical studies; sponsoring symposia and other programs to encourage scientific cooperation, collaboration, and communication among researchers, the medical community, goverment organizations, and the patient community.

Last Updated: 15 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anemia" for support, advocacy or research.

Logo
Mucolipidosis Type IV (ML4) Foundation

The mission of the Foundation is to fund, promote and support scientific research dedicated to developing treatments and a cure for ML4 by providing critical financial support to researchers; linking individuals with ML4 to researchers for clinical studies; sponsoring symposia and other programs to encourage scientific cooperation, collaboration, and communication among researchers, the medical community, goverment organizations, and the patient community.

http://www.ml4.org

Last Updated: 15 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anemia" returned 5344 free, full-text research articles on human participants. First 3 results:

Impaired Autophagy in Adult Bone Marrow CD34+ Cells of Patients with Aplastic Anemia: Possible Pathogenic Significance.
 

Author(s): Jinbo Huang, Meili Ge, Shihong Lu, Jun Shi, Wei Yu, Xingxin Li, Min Wang, Jizhou Zhang, Sizhou Feng, Shuxu Dong, Xuelian Cheng, Yizhou Zheng

Journal:

 

Aplastic anemia (AA) is a bone marrow failure syndrome that is caused largely by profound quantitative and qualitative defects of hematopoietic stem and progenitor cells. However, the mechanisms underlying these defects remain unclear. Under conditions of stress, autophagy acts as ...

Last Updated: 2 Mar 2016

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Drug-Induced Megaloblastic Anemia.
 

Author(s): Charles S Hesdorffer, Dan L Longo

Journal: N. Engl. J. Med.. 2016 Feb;374(7):696-7.

 

Last Updated: 18 Feb 2016

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Anemia on Admission Is an Independent Predictor of Long-Term Mortality in Hip Fracture Population: A Prospective Study With 2-Year Follow-Up.
 

Author(s): Licheng Zhang, Pengbin Yin, Houchen Lv, Anhua Long, Yuan Gao, Lihai Zhang, Peifu Tang

Journal: Medicine (Baltimore). 2016 Feb;95(5):e2469.

 

Anemia is a disputable factor for long-term mortality in hip fracture population in previous studies. Previous studies indicated that the level of hemoglobin (Hb) might fluctuate due to various factors, such as comorbidities and in-hospital interventions, and the changing level of ...

Last Updated: 5 Feb 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anemia" returned 479 free, full-text review articles on human participants. First 3 results:

Prevention of Iatrogenic Anemia in Critical and Neonatal Care.
 

Author(s): Natalia Jakacka, Emilian Snarski, Selamawit Mekuria

Journal: Adv Clin Exp Med. ;25(1):191-7.

 

Iatrogenic anemia caused by diagnostic blood sampling is a common problem in the intensive care unit, where continuous monitoring of blood parameters is very often required. Cumulative blood loss associated with phlebotomy along with other factors render this group of patients particularly ...

Last Updated: 3 Mar 2016

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Intravenous Versus Oral Iron for the Treatment of Anemia in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
 

Author(s): Stefanos Bonovas, Gionata Fiorino, Mariangela Allocca, Theodore Lytras, Argirios Tsantes, Laurent Peyrin-Biroulet, Silvio Danese

Journal: Medicine (Baltimore). 2016 Jan;95(2):e2308.

 

Anemia is the most prevalent extraintestinal complication of inflammatory bowel disease (IBD). Our aim was to evaluate the comparative efficacy and harm of intravenous (IV) versus oral iron supplementation for correcting anemia in adult IBD patients.We conducted a systematic review ...

Last Updated: 15 Jan 2016

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Effect of NaFeEDTA-Fortified Soy Sauce on Anemia Prevalence in China: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
 

Author(s): Jun Sheng Huo, Ji Yong Yin, Jing Sun, Jian Huang, Zhen Xin Lu, Moench-Pfanner Regina, Jun Shi Chen, Chun Ming Chen

Journal: Biomed. Environ. Sci.. 2015 Nov;28(11):788-98.

 

To assess the effect of sodium iron ethylenediaminetetraacetate (NaFeEDTA)-fortified soy sauce on anemia prevalence in the Chinese population.

Last Updated: 23 Dec 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias
 

Status: Recruiting

Condition Summary: Congenital Hemolytic Anemia; Diamond-Blackfan Anemia

 

Last Updated: 19 Jul 2016

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Eltrombopag for Moderate Aplastic Anemia
 

Status: Recruiting

Condition Summary: Eltrombopag; Aplastic Anemia; Aplastic Anemia Treatment; Moderate Aplastic Anemia; Moderate Aplastic Anemia Treatment; Unilineage Bone Marrow Failure Disorders

 

Last Updated: 22 Jul 2016

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Safety and Efficacy Study of Sotatercept in Adults With Transfusion Dependent Diamond Blackfan Anemia
 

Status: Recruiting

Condition Summary: Diamond Blackfan Anemia

 

Last Updated: 15 Jun 2016

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