Anemia

Common Name(s)

Anemia, Anemias

Anemia occurs when there is a decreased amount of hemoglobin, an iron-rich protein inside red blood cells, that helps carry oxygen throughout the body. Symptoms include general weakness, tiredness, difficulty concentrating, shortness of breath, confusion, dizziness, headaches, brittle nails, pale skin, and lightheadedness. Severe anemia, when it goes untreated, can cause heart and other organ failures, and in rare and extreme cases, even death. Although there are many types of anemia, anemias are categroized into three main groups: anemia caused by blood loss, anemia caused by decreased red blood cell production, and anemia caused by the destruction of red blood cells. Anemia through blood loss is usually caused from gastrointestinal bleeding such as ulcers or hemorrhoids, but can also occur from surgery or frequent blood donations. Anemia is also more commonly in females than in males due to menstruation and pregnancy. Anemia due to a lack of red blood cell production or increased red blood cell destruction can be due to abnormal red blood cells or various other conditions or factors including sickle cell anemia, iron and other vitamin deficiencies, poor dieting, bone marrow conditions, organ irregularities, infections, and toxins. Anemia can be diagnosed through a physical examination and a simple blood test, although diagnosing the type of anemia may require more tests. Treatments vary depending on the severity and kind of the anemia including proper dieting, iron, B12 or other vitamin supplements, blood transfusions, and special drugs such as corticosteroids and erythropoietin. Talk to your doctor if you may be experiencing the symptoms.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anemia" for support, advocacy or research.

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Mucolipidosis Type IV (ML4) Foundation

The mission of the Foundation is to fund, promote and support scientific research dedicated to developing treatments and a cure for ML4 by providing critical financial support to researchers; linking individuals with ML4 to researchers for clinical studies; sponsoring symposia and other programs to encourage scientific cooperation, collaboration, and communication among researchers, the medical community, goverment organizations, and the patient community.

Last Updated: 15 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anemia" for support, advocacy or research.

Logo
Mucolipidosis Type IV (ML4) Foundation

The mission of the Foundation is to fund, promote and support scientific research dedicated to developing treatments and a cure for ML4 by providing critical financial support to researchers; linking individuals with ML4 to researchers for clinical studies; sponsoring symposia and other programs to encourage scientific cooperation, collaboration, and communication among researchers, the medical community, goverment organizations, and the patient community.

http://www.ml4.org

Last Updated: 15 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anemia" returned 4047 free, full-text research articles on human participants. First 3 results:

Transfusions for silent cerebral infarcts in sickle cell anemia.
 

Author(s): Michael R DeBaun, James F Casella

Journal: N. Engl. J. Med.. 2014 Nov;371(19):1841-2.

 

Last Updated: 6 Nov 2014

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Impact of multiple micronutrient supplementation ("sprinkles") on iron deficiency anemia in Bedouin Arab and Jewish infants.
 

Author(s): Natalya Bilenko, Drora Fraser, Hillel Vardy, Ilana Belmaker

Journal: Isr. Med. Assoc. J.. 2014 Jul;16(7):434-8.

 

A high prevalence of iron deficiency anemia persists in Bedouin Arab and Jewish pediatric populations in southern Israel.

Last Updated: 29 Aug 2014

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Busuishengxue ranules mediate their effects upon non-severe aplastic anemia via mitogen-activated protein kinase/extracellular signal-regulated kinase pathway.
 

Author(s): Jinhuan Wang, Feng Sun, Weizheng Sun, Haitao Shi, Yanli Yong, Sijia Liu, Limei Liu

Journal: J Tradit Chin Med. 2014 Feb;34(1):23-9.

 

To observe the clinical efficacy of Busuishengxue granules on non-severe aplastic anemia (NSAA) and investigate its effect on the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) pathway.

Last Updated: 8 Aug 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anemia" returned 415 free, full-text review articles on human participants. First 3 results:

Aplastic anemia in adolescents and young adults.
 

Author(s): Amy E DeZern, Eva C Guinan

Journal: Acta Haematol.. 2014 ;132(3-4):331-9.

 

Adolescent and young adult patient presentations of aplastic anemia require a particular perspective on both diagnosis and treatment. This unique age group necessitates a thorough diagnostic evaluation to ensure the etiology, acquired or inherited, is sufficiently determined. The ...

Last Updated: 17 Sep 2014

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[Hepcidin as a central mediator of anemia of chronic diseases associated with obesity].
 

Author(s): Pía Villarroel H, Miguel Arredondo O, Manuel Olivares G

Journal: Rev Med Chil. 2013 Jul;141(7):887-94.

 

Recent evidence suggests that obesity-related inflammation may play a central role in hepcidin regulation. Hepcidin is a key regulator ofiron homeostasis and has now been suggested as a central mediator ofiron metabolism disorders involved in the pathogenesis of anemia of chronic ...

Last Updated: 20 Dec 2013

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Fanconi anemia: a signal transduction and DNA repair pathway.
 

Author(s): Gary M Kupfer

Journal:

 

Fanconi anemia (FA) is a fascinating, rare genetic disorder marked by congenital defects, bone marrow failure, and cancer susceptibility. Research in recent years has led to the elucidation of FA as a DNA repair disorder and involved multiple pathways as well as having wide applicability ...

Last Updated: 18 Dec 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Identification of de Novo Fanconi Anemia in Younger Patients With Newly Diagnosed Acute Myeloid Leukemia
 

Status: Recruiting

Condition Summary: Childhood Acute Erythroleukemia (M6); Childhood Acute Megakaryocytic Leukemia (M7); Childhood Acute Minimally Differentiated Myeloid Leukemia (M0); Childhood Acute Monoblastic Leukemia (M5a); Childhood Acute Monocytic Leukemia (M5b); Childhood Acute Myeloblastic Leukemia With Maturation (M2); Childhood Acute Myeloblastic Leukemia Without Maturation (M1); Childhood Acute Myelomonocytic Leukemia (M4); Childhood Myelodysplastic Syndromes; Chronic Myelomonocytic Leukemia; de Novo Myelodysplastic Syndromes; Fanconi Anemia; Refractory Anemia; Refractory Anemia With Excess Blasts; Refractory Anemia With Excess Blasts in Transformation; Refractory Anemia With Ringed Sideroblasts; Secondary Myelodysplastic Syndromes; Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies

 

Last Updated: 14 Feb 2014

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Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias
 

Status: Recruiting

Condition Summary: Congenital Hemolytic Anemia; Diamond-Blackfan Anemia

 

Last Updated: 22 Nov 2014

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Eltrombopag for Moderate Aplastic Anemia
 

Status: Recruiting

Condition Summary: Eltrombopag; Aplastic Anemia; Aplastic Anemia Treatment; Moderate Aplastic Anemia; Moderate Aplastic Anemia Treatment

 

Last Updated: 22 Nov 2014

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