Anemia

Common Name(s)

Anemia, Anemias

Anemia occurs when there is a decreased amount of hemoglobin, an iron-rich protein inside red blood cells, that helps carry oxygen throughout the body. Symptoms include general weakness, tiredness, difficulty concentrating, shortness of breath, confusion, dizziness, headaches, brittle nails, pale skin, and lightheadedness. Severe anemia, when it goes untreated, can cause heart and other organ failures, and in rare and extreme cases, even death. Although there are many types of anemia, anemias are categorized into three main groups: anemia caused by blood loss, anemia caused by decreased red blood cell production, and anemia caused by the destruction of red blood cells. Anemia through blood loss is usually caused from gastrointestinal bleeding such as ulcers or hemorrhoids, but can also occur from surgery or frequent blood donations. Anemia is also more commonly in females than in males due to menstruation and pregnancy. Anemia due to a lack of red blood cell production or increased red blood cell destruction can be due to abnormal red blood cells or various other conditions or factors including sickle cell anemia, iron and other vitamin deficiencies, poor dieting, bone marrow conditions, organ irregularities, infections, and toxins.

Anemia can be diagnosed through a physical examination and a simple blood test, although diagnosing the type of anemia may require more tests. Treatments vary depending on the severity and kind of the anemia including proper dieting, iron, and vitamin supplements. If the anemia is severe other treatments, including blood transfusions or medications, may be needed. If you or a family member has been diagnosed with anemia, talk to your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anemia" for support, advocacy or research.

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Mucolipidosis Type IV (ML4) Foundation

The mission of the Foundation is to fund, promote and support scientific research dedicated to developing treatments and a cure for ML4 by providing critical financial support to researchers; linking individuals with ML4 to researchers for clinical studies; sponsoring symposia and other programs to encourage scientific cooperation, collaboration, and communication among researchers, the medical community, goverment organizations, and the patient community.

Last Updated: 15 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anemia" for support, advocacy or research.

Logo
Mucolipidosis Type IV (ML4) Foundation

The mission of the Foundation is to fund, promote and support scientific research dedicated to developing treatments and a cure for ML4 by providing critical financial support to researchers; linking individuals with ML4 to researchers for clinical studies; sponsoring symposia and other programs to encourage scientific cooperation, collaboration, and communication among researchers, the medical community, goverment organizations, and the patient community.

http://www.ml4.org

Last Updated: 15 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anemia" returned 5248 free, full-text research articles on human participants. First 3 results:

Drug-Induced Megaloblastic Anemia.
 

Author(s): Charles S Hesdorffer, Dan L Longo

Journal: N. Engl. J. Med.. 2016 Feb;374(7):696-7.

 

Last Updated: 18 Feb 2016

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The effects of cinacalcet treatment on bone mineral metabolism, anemia parameters, left ventricular mass index and parathyroid gland volume in hemodialysis patients with severe secondary hyperparathyroidism.
 

Author(s): Dilek Torun, Ismail Yildiz, Hasan Micozkadioglu, Gul Nihal Nursal, Fatma Yigit, Ruya Ozelsancak

Journal: Saudi J Kidney Dis Transpl. 2016 Jan;27(1):15-22.

 

The aim of this study was to investigate the effects of cinacalcet therapy on anemia parameters, bone mineral metabolism, left ventricular mass index (LVMI) and parathyroid gland volume in hemodialysis (HD) patients with secondary hyperparathyroidism. Twenty-five HD patients (M/F: ...

Last Updated: 20 Jan 2016

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Vitamin D Status and the Risk of Anemia in Community-Dwelling Adults: Results from the National Health and Nutrition Examination Survey 2001-2006.
 

Author(s): Dominique J Monlezun, Carlos A Camargo, John T Mullen, Sadeq A Quraishi

Journal: Medicine (Baltimore). 2015 Dec;94(50):e1799.

 

Low vitamin D status has been implicated in several chronic medical conditions and unfavorable health outcomes. Our goal was to investigate whether serum 25-hydroxyvitamin D (25OHD) levels are a potentially modifiable risk factor for anemia in a nationally representative cohort of ...

Last Updated: 19 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anemia" returned 462 free, full-text review articles on human participants. First 3 results:

Type 1 Diabetes Mellitus and Pernicious Anemia in an Elderly Japanese Patient: A Case Report and Literature Review.
 

Author(s): Nobumasa Ohara, Masanori Kaneko, Toshio Yano, Naoko Sato, Hiroyuki Usuda, Masashi Miyakoshi, Tatsuo Furukawa, Tadashi Koike, Kenzo Kaneko, Kyuzi Kamoi

Journal: Intern. Med.. 2015 ;54(18):2361-5.

 

We herein report the case of a 66-year-old Japanese man with acute-onset type 1 diabetes mellitus (T1D) accompanied by pernicious anemia. After 2 weeks of polyuria, the patient developed insulin-deficient hyperglycemia with diabetic ketoacidosis in the absence of verifiable islet-related ...

Last Updated: 15 Sep 2015

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Autoimmune hemolytic anemia associated with renal urothelial cancer: A case report and literature review.
 

Author(s): Shuji Isotani, Akira Horiuchi, Masayuki Koja, Takahiro Noguchi, Shouichiro Sugiura, Hirofumi Shimoyama, Yasuhiro Noma, Kousuke Kitamura, Toshiyuki China, Shino Tokiwa, Keisuke Saito, Masaki Kimura, Shin-ichi Hisasue, Hisamitsu Ide, Satoru Muto, Raizo Yamaguchi, Shigeo Horie

Journal:

 

Autoimmune hemolytic anemia (AIHA) is hemolytic anemia characterized by autoantibodies directed against red blood cells. AIHA can be induced by hematological neoplasms such as malignant lymphoma, but is rarely observed in the urological field. We report a case of renal urothelial ...

Last Updated: 28 Jul 2015

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Management of Iron-Deficiency Anemia in Inflammatory Bowel Disease: A Systematic Review.
 

Author(s): Ole Haagen Nielsen, Mark Ainsworth, Mehmet Coskun, G√ľnter Weiss

Journal: Medicine (Baltimore). 2015 Jun;94(23):e963.

 

Anemia is the most frequent complication of inflammatory bowel disease (IBD), but anemia, mostly due to iron deficiency, has long been neglected in these patients. The aim was to briefly present the pathophysiology, followed by a balanced overview of the different forms of iron replacement ...

Last Updated: 11 Jun 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Identification of de Novo Fanconi Anemia in Younger Patients With Newly Diagnosed Acute Myeloid Leukemia
 

Status: Recruiting

Condition Summary: Childhood Acute Erythroleukemia (M6); Childhood Acute Megakaryocytic Leukemia (M7); Childhood Acute Minimally Differentiated Myeloid Leukemia (M0); Childhood Acute Monoblastic Leukemia (M5a); Childhood Acute Monocytic Leukemia (M5b); Childhood Acute Myeloblastic Leukemia With Maturation (M2); Childhood Acute Myeloblastic Leukemia Without Maturation (M1); Childhood Acute Myelomonocytic Leukemia (M4); Childhood Myelodysplastic Syndromes; Chronic Myelomonocytic Leukemia; de Novo Myelodysplastic Syndromes; Fanconi Anemia; Refractory Anemia; Refractory Anemia With Excess Blasts; Refractory Anemia With Excess Blasts in Transformation; Refractory Anemia With Ringed Sideroblasts; Secondary Myelodysplastic Syndromes; Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies

 

Last Updated: 5 Nov 2015

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Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias
 

Status: Recruiting

Condition Summary: Congenital Hemolytic Anemia; Diamond-Blackfan Anemia

 

Last Updated: 20 Jan 2016

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A Pilot, Phase I/II Study of the Amino Acid Leucine in the Treatment of Patients With Transfusion-Dependent Diamond Blackfan Anemia
 

Status: Recruiting

Condition Summary: Diamond Blackfan Anemia; Blackfan Diamond Syndrome; DBA; Congenital Hypoplastic Anemia; Pure Red Cell Aplasia

 

Last Updated: 19 Nov 2015

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