Macular Dystrophy

Common Name(s)

Macular Dystrophy

Macular dystrophy is a genetic eye disorder that causes vision loss. It causes damage to the area of the eye called the macula, which is responsible for central vision. When the macula is damaged, people have trouble seeing straight ahead. Vision becomes blurry and distorted. However, side (peripheral) vision is not affected. Vision slowly worsens over time. Unfortunately, there is no treatment available for macular dystrophy at this time. However, promising new research is currently being conducted.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Macular Dystrophy" for support, advocacy or research.

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Macular Dystrophy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Macular Dystrophy" returned 144 free, full-text research articles on human participants. First 3 results:

New CDH3 mutation in the first Spanish case of hypotrichosis with juvenile macular dystrophy, a case report.
 

Author(s): Fiona Blanco-Kelly, Luciana Rodrigues-Jacy da Silva, Iker Sanchez-Navarro, Rosa Riveiro-Alvarez, Miguel Angel Lopez-Martinez, Marta Corton, Carmen Ayuso

Journal:

 

CDH3 on 16q22.1 is responsible for two rare autosomal recessive disorders with hypotrichosis and progressive macular dystrophy: Hypotrichosis with Juvenile Macular Dystrophy and Ectodermal Dysplasia, Ectrodactyly and Macular Dystrophy. We present a new case of Hypotrichosis with Juvenile ...

Last Updated: 7 Jan 2017

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Novel mutation in the CHST6 gene causes macular corneal dystrophy in a black South African family.
 

Author(s): Nadia Carstens, Susan Williams, Saadiah Goolam, Trevor Carmichael, Ming Sin Cheung, Stine Büchmann-Møller, Marc Sultan, Frank Staedtler, Chao Zou, Peter Swart, Dennis S Rice, Arnaud Lacoste, Kim Paes, Michèle Ramsay

Journal:

 

Macular corneal dystrophy (MCD) is a rare autosomal recessive disorder that is characterized by progressive corneal opacity that starts in early childhood and ultimately progresses to blindness in early adulthood. The aim of this study was to identify the cause of MCD in a black South ...

Last Updated: 21 Jul 2016

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Comparison of Short-Wavelength Reduced-Illuminance and Conventional Autofluorescence Imaging in Stargardt Macular Dystrophy.
 

Author(s): Rupert W Strauss, Beatriz Muñoz, Anamika Jha, Alexander Ho, Artur V Cideciyan, Melissa L Kasilian, Yulia Wolfson, SriniVas Sadda, Sheila West, Hendrik P N Scholl, Michel Michaelides

Journal: Am. J. Ophthalmol.. 2016 Aug;168():269-78.

 

To compare grading results between short-wavelength reduced-illuminance and conventional autofluorescence imaging in Stargardt macular dystrophy.

Last Updated: 1 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Macular Dystrophy" returned 3 free, full-text review articles on human participants. First 3 results:

Macular pattern dystrophy and homonymous hemianopia in MELAS syndrome.
 

Author(s): Radua Kamal-Salah, Isabel Baquero-Aranda, María Del Mar Grana-Pérez, Jose Manuel García-Campos

Journal:

 

We report an unusual association of a pattern dystrophy of the retinal pigment epithelium and homonymous hemianopia in a woman diagnosed with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes syndrome.

Last Updated: 13 Mar 2015

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Macular dystrophy associated with the mitochondrial DNA A3243G mutation: pericentral pigment deposits or atrophy? Report of two cases and review of the literature.
 

Author(s): Alejandra Daruich, Alexandre Matet, François-Xavier Borruat

Journal:

 

The A3243G point mutation in mitochondrial DNA (mtDNA) is associated with MELAS (mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes) and MIDD syndromes (maternally inherited diabetes and deafness). Both MELAS and MIDD patients can present with visual symptoms ...

Last Updated: 17 Jun 2014

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Macular corneal dystrophy. Studies of sulfated glycosaminoglycans in corneal explant and confluent stromal cell cultures.
 

Author(s): G K Klintworth, C F Smith

Journal: Am. J. Pathol.. 1977 Oct;89(1):167-82.

 

The inherited disorder macular corneal dystrophy (MCD), a localized corneal mucopolysaccharidosis, is currently thought to result from an inability to catabolize corneal keratan sulfate (keratan sulfate 1). As studies on isolated cells have provided insight into metabolic abnormalities ...

Last Updated: 30 Nov 1977

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 20 Apr 2016

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Age-Related Macular Degeneration, Scotopic Dysfunction, and Driving Performance in a Simulator
 

Status: Not yet recruiting

Condition Summary: Age-related Macular Degeneration

 

Last Updated: 24 May 2017

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