Lymphatic filariasis

Common Name(s)

Lymphatic filariasis

Lymphatic filariasis is a parasitic disease caused by microscopic, thread-like worms that only live in the human lymph system, which maintains the body's fluid balance and fights infections. It is spread from person to person by mosquitoes. Most infected people are asymptomatic and never develop clinical symptoms. A small percentage of people develop lymphedema, which may affect the legs, arms, breasts, and genitalia; bacterial infections that cause hardening and thickening of the skin, called elephantiasis; hydrocele (swelling of the scrotum) in men; and pulmonary tropical eosinophilia syndrome. Treatment may include a yearly dose of medicine, called diethylcarbamazine (DEC); while this drug does not kill all of the adult worms, it prevents infected people from giving the disease to someone else.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lymphatic filariasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lymphatic filariasis" returned 298 free, full-text research articles on human participants. First 3 results:

Accuracy of Coverage Survey Recall following an Integrated Mass Drug Administration for Lymphatic Filariasis, Schistosomiasis, and Soil-Transmitted Helminthiasis.
 

Author(s): Philip J Budge, Edmond Sognikin, Amanda Akosa, Els M Mathieu, Michael Deming

Journal:

 

Achieving target coverage levels for mass drug administration (MDA) is essential to elimination and control efforts for several neglected tropical diseases (NTD). To ensure program goals are met, coverage reported by drug distributors may be validated through household coverage surveys ...

Last Updated: 15 Jan 2016

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Cross-Reactivity of Filariais ICT Cards in Areas of Contrasting Endemicity of Loa loa and Mansonella perstans in Cameroon: Implications for Shrinking of the Lymphatic Filariasis Map in the Central African Region.
 

Author(s): Samuel Wanji, Nathalie Amvongo-Adjia, Benjamin Koudou, Abdel Jelil Njouendou, Patrick W Chounna Ndongmo, Jonas A Kengne-Ouafo, Fabrice R Datchoua-Poutcheu, Bridget Adzemye Fovennso, Dizzle Bita Tayong, Fanny Fri Fombad, Peter U Fischer, Peter I Enyong, Moses Bockarie

Journal:

 

Immunochromatographic card test (ICT) is a tool to map the distribution of Wuchereria bancrofti. In areas highly endemic for loaisis in DRC and Cameroon, a relationship has been envisaged between high L. loa microfilaria (Mf) loads and ICT positivity. However, similar associations ...

Last Updated: 7 Nov 2015

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Shrinking the Lymphatic Filariasis Map of Ethiopia: Reassessing the Population at Risk through Nationwide Mapping.
 

Author(s): Maria P Rebollo, Heven Sime, Ashenafi Assefa, Jorge Cano, Kebede Deribe, Alba Gonzalez-Escalada, Oumer Shafi, Gail Davey, Simon J Brooker, Amha Kebede, Moses J Bockarie

Journal:

 

Mapping of lymphatic filariasis (LF) is essential for the delineation of endemic implementation units and determining the population at risk that will be targeted for mass drug administration (MDA). Prior to the current study, only 116 of the 832 woredas (districts) in Ethiopia had ...

Last Updated: 6 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lymphatic filariasis" returned 32 free, full-text review articles on human participants. First 3 results:

The Effect of Hygiene-Based Lymphedema Management in Lymphatic Filariasis-Endemic Areas: A Systematic Review and Meta-analysis.
 

Author(s): Meredith E Stocks, Matthew C Freeman, David G Addiss

Journal:

 

Lymphedema of the leg and its advanced form, known as elephantiasis, are significant causes of disability and morbidity in areas endemic for lymphatic filariasis (LF), with an estimated 14 million persons affected worldwide. The twin goals of the World Health Organization's Global ...

Last Updated: 27 Oct 2015

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Non-endemic cases of lymphatic filariasis.
 

Author(s): Robert T Jones

Journal: Trop. Med. Int. Health. 2014 Nov;19(11):1377-83.

 

Several cases of lymphatic filariasis (LF) have been reported in non-endemic countries due to travellers, military personnel and expatriates spending time in and returning from endemic areas, as well as immigrants coming from these regions. These cases are reviewed to assess the scale ...

Last Updated: 8 Oct 2014

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A review of factors that influence individual compliance with mass drug administration for elimination of lymphatic filariasis.
 

Author(s): Alison Krentel, Peter U Fischer, Gary J Weil

Journal:

 

The success of programs to eliminate lymphatic filariasis (LF) depends in large part on their ability to achieve and sustain high levels of compliance with mass drug administration (MDA). This paper reports results from a comprehensive review of factors that affect compliance with MDA.

Last Updated: 26 Nov 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Mass Drug Administration for Lymphatic Filariasis and Onchocerciasis for Liberia
 

Status: Recruiting

Condition Summary: Lymphatic Filariasis; Onchocerciasis; Soil Transmitted Helminth (STH) Infections

 

Last Updated: 11 Dec 2015

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Optimization of Mass Drug Administration With Existing Drug Regimens for Lymphatic Filariasis and Onchocerciasis for Ivory Coast (DOLF-Ivory Coast)
 

Status: Recruiting

Condition Summary: Lymphatic Filariasis; Onchocerciasis; Soil Transmitted Helminth (STH) Infections

 

Last Updated: 2 May 2016

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Exhaled NO Testing in Filariasis
 

Status: Recruiting

Condition Summary: Filariasis

 

Last Updated: 22 Jun 2012

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