Lymphatic filariasis

Common Name(s)

Lymphatic filariasis

Lymphatic filariasis is a parasitic disease caused by microscopic, thread-like worms that only live in the human lymph system, which maintains the body's fluid balance and fights infections. It is spread from person to person by mosquitoes. Most infected people are asymptomatic and never develop clinical symptoms. A small percentage of people develop lymphedema, which may affect the legs, arms, breasts, and genitalia; bacterial infections that cause hardening and thickening of the skin, called elephantiasis; hydrocele (swelling of the scrotum) in men; and pulmonary tropical eosinophilia syndrome. Treatment may include a yearly dose of medicine, called diethylcarbamazine (DEC); while this drug does not kill all of the adult worms, it prevents infected people from giving the disease to someone else.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lymphatic filariasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lymphatic filariasis" returned 305 free, full-text research articles on human participants. First 3 results:

Prevalence of Lymphatic Filariasis and Treatment Effectiveness of Albendazole/ Ivermectin in Individuals with HIV Co-infection in Southwest-Tanzania.
 

Author(s): Inge Kroidl, Elmar Saathof, Lucas Maganga, Petra Clowes, Leonard Maboko, Achim Hoerauf, Williams H Makunde, Antelmo Haule, Prisca Mviombo, Bettina Pitter, Neema Mgeni, Joseph Mabuye, Dickens Kowuor, Upendo Mwingira, Mwelecele N Malecela, Thomas Löscher, Michael Hoelscher

Journal:

 

Annual mass treatment with ivermectin and albendazole is used to treat lymphatic filariasis in many African countries, including Tanzania. In areas where both diseases occur, it is unclear whether HIV co-infection reduces treatment success.

Last Updated: 13 Apr 2016

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Assessing Lymphatic Filariasis Data Quality in Endemic Communities in Ghana, Using the Neglected Tropical Diseases Data Quality Assessment Tool for Preventive Chemotherapy.
 

Author(s): Dziedzom K de Souza, Eric Yirenkyi, Joseph Otchere, Nana-Kwadwo Biritwum, Donne K Ameme, Samuel Sackey, Collins Ahorlu, Michael D Wilson

Journal:

 

The activities of the Global Programme for the Elimination of Lymphatic Filariasis have been in operation since the year 2000, with Mass Drug Administration (MDA) undertaken yearly in disease endemic communities. Information collected during MDA-such as population demographics, age, ...

Last Updated: 31 Mar 2016

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Experiences of a Community-Based Lymphedema Management Program for Lymphatic Filariasis in Odisha State, India: An Analysis of Focus Group Discussions with Patients, Families, Community Members and Program Volunteers.
 

Author(s): Tali Cassidy, Caitlin M Worrell, Kristen Little, Aishya Prakash, Inakhi Patra, Jonathan Rout, LeAnne M Fox

Journal:

 

Globally 68 million people are infected with lymphatic filariasis (LF), 17 million of whom have lymphedema. This study explores the effects of a lymphedema management program in Odisha State, India on morbidity and psychosocial effects associated with lymphedema.

Last Updated: 6 Feb 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lymphatic filariasis" returned 33 free, full-text review articles on human participants. First 3 results:

The Effect of Hygiene-Based Lymphedema Management in Lymphatic Filariasis-Endemic Areas: A Systematic Review and Meta-analysis.
 

Author(s): Meredith E Stocks, Matthew C Freeman, David G Addiss

Journal:

 

Lymphedema of the leg and its advanced form, known as elephantiasis, are significant causes of disability and morbidity in areas endemic for lymphatic filariasis (LF), with an estimated 14 million persons affected worldwide. The twin goals of the World Health Organization's Global ...

Last Updated: 27 Oct 2015

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An investigation of the disparity in estimates of microfilaraemia and antigenaemia in lymphatic filariasis surveys.
 

Author(s): Jorge Cano, Paula Moraga, Birgit Nikolay, Maria P Rebollo, Patricia N Okorie, Emmanuel Davies, Sammy M Njenga, Moses J Bockarie, Simon J Brooker

Journal: Trans. R. Soc. Trop. Med. Hyg.. 2015 Aug;109(8):529-31.

 

The diagnosis of lymphatic filariasis (LF) is based typically on either microfilaraemia as assessed by microscopy or filarial antigenaemia using an immuno-chromatographic test. While it is known that estimates of antigenaemia are generally higher than estimates of microfilaraemia, ...

Last Updated: 16 Jul 2015

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Non-endemic cases of lymphatic filariasis.
 

Author(s): Robert T Jones

Journal: Trop. Med. Int. Health. 2014 Nov;19(11):1377-83.

 

Several cases of lymphatic filariasis (LF) have been reported in non-endemic countries due to travellers, military personnel and expatriates spending time in and returning from endemic areas, as well as immigrants coming from these regions. These cases are reviewed to assess the scale ...

Last Updated: 8 Oct 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Mass Drug Administration for Lymphatic Filariasis and Onchocerciasis for Liberia
 

Status: Recruiting

Condition Summary: Lymphatic Filariasis; Onchocerciasis; Soil Transmitted Helminth (STH) Infections

 

Last Updated: 11 Dec 2015

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Optimization of Mass Drug Administration With Existing Drug Regimens for Lymphatic Filariasis and Onchocerciasis for Ivory Coast (DOLF-Ivory Coast)
 

Status: Recruiting

Condition Summary: Lymphatic Filariasis; Onchocerciasis; Soil Transmitted Helminth (STH) Infections

 

Last Updated: 2 May 2016

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Exhaled NO Testing in Filariasis
 

Status: Recruiting

Condition Summary: Filariasis

 

Last Updated: 22 Jun 2012

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