Lymphatic filariasis

Common Name(s)

Lymphatic filariasis

Lymphatic filariasis is a parasitic disease caused by microscopic, thread-like worms that only live in the human lymph system, which maintains the body's fluid balance and fights infections. It is spread from person to person by mosquitoes. Most infected people are asymptomatic and never develop clinical symptoms. A small percentage of people develop lymphedema, which may affect the legs, arms, breasts, and genitalia; bacterial infections that cause hardening and thickening of the skin, called elephantiasis; hydrocele (swelling of the scrotum) in men; and pulmonary tropical eosinophilia syndrome. Treatment may include a yearly dose of medicine, called diethylcarbamazine (DEC); while this drug does not kill all of the adult worms, it prevents infected people from giving the disease to someone else.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lymphatic filariasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lymphatic filariasis" returned 274 free, full-text research articles on human participants. First 3 results:

489 Global programme to eliminate lymphatic filariasis: progress report, 2014.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2015 Sep;90(38):489-504.

 

Last Updated: 18 Sep 2015

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Developing a community-led SMS reporting tool for the rapid assessment of lymphatic filariasis morbidity burden: case studies from Malawi and Ghana.
 

Author(s): Michelle C Stanton, Square Z Mkwanda, Alexander Y Debrah, Linda Batsa, Nana-Kwadwo Biritwum, Achim Hoerauf, Matthew Cliffe, Abigail Best, Andrew Molineux, Louise A Kelly-Hope

Journal:

 

Lymphoedema and hydrocoele are the two most common clinical manifestations of lymphatic filariasis (LF). In order to effectively target morbidity management strategies, more information is rapidly needed on morbidity burden across all endemic countries. The purpose of this study was ...

Last Updated: 22 May 2015

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Cessation of mass drug administration for lymphatic filariasis in Zanzibar in 2006: was transmission interrupted?
 

Author(s): Maria P Rebollo, Khalfan A Mohammed, Brent Thomas, Shaali Ame, Said Mohammed Ali, Jorge Cano, Alba Gonzalez Escalada, Moses J Bockarie

Journal:

 

Lymphatic filariasis (LF) is targeted for elimination through annual mass drug administration (MDA) for 4-6 years. In 2006, Zanzibar stopped MDA against LF after five rounds of MDA revealed no microfilaraemic individuals during surveys at selected sentinel sites. We asked the question ...

Last Updated: 30 Mar 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lymphatic filariasis" returned 27 free, full-text review articles on human participants. First 3 results:

Non-endemic cases of lymphatic filariasis.
 

Author(s): Robert T Jones

Journal: Trop. Med. Int. Health. 2014 Nov;19(11):1377-83.

 

Several cases of lymphatic filariasis (LF) have been reported in non-endemic countries due to travellers, military personnel and expatriates spending time in and returning from endemic areas, as well as immigrants coming from these regions. These cases are reviewed to assess the scale ...

Last Updated: 8 Oct 2014

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A review of factors that influence individual compliance with mass drug administration for elimination of lymphatic filariasis.
 

Author(s): Alison Krentel, Peter U Fischer, Gary J Weil

Journal:

 

The success of programs to eliminate lymphatic filariasis (LF) depends in large part on their ability to achieve and sustain high levels of compliance with mass drug administration (MDA). This paper reports results from a comprehensive review of factors that affect compliance with MDA.

Last Updated: 26 Nov 2013

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Drug targets for lymphatic filariasis: a bioinformatics approach.
 

Author(s): Om Prakash Sharma, Yellamandaya Vadlamudi, Arun Gupta Kota, Vikrant Kumar Sinha, Muthuvel Suresh Kumar

Journal: J Vector Borne Dis. 2013 Sep;50(3):155-62.

 

This review article discusses the current scenario of the national and international burden due to lymphatic filariasis (LF) and describes the active elimination programmes for LF and their achievements to eradicate this most debilitating disease from the earth. Since, bioinformatics ...

Last Updated: 13 Nov 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Mass Drug Administration for Lymphatic Filariasis and Onchocerciasis for Liberia
 

Status: Recruiting

Condition Summary: Lymphatic Filariasis; Onchocerciasis; Soil Transmitted Helminth (STH) Infections

 

Last Updated: 11 Dec 2015

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Optimization of Mass Drug Administration With Existing Drug Regimens for Lymphatic Filariasis and Onchocerciasis for Ivory Coast (DOLF-Ivory Coast)
 

Status: Recruiting

Condition Summary: Lymphatic Filariasis; Onchocerciasis; Soil Transmitted Helminth (STH) Infections

 

Last Updated: 26 Aug 2015

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Exhaled NO Testing in Filariasis
 

Status: Recruiting

Condition Summary: Filariasis

 

Last Updated: 22 Jun 2012

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