Lymphatic filariasis

Common Name(s)

Lymphatic filariasis

Lymphatic filariasis is a parasitic disease caused by microscopic, thread-like worms that only live in the human lymph system, which maintains the body's fluid balance and fights infections. It is spread from person to person by mosquitoes. Most infected people are asymptomatic and never develop clinical symptoms. A small percentage of people develop lymphedema, which may affect the legs, arms, breasts, and genitalia; bacterial infections that cause hardening and thickening of the skin, called elephantiasis; hydrocele (swelling of the scrotum) in men; and pulmonary tropical eosinophilia syndrome. Treatment may include a yearly dose of medicine, called diethylcarbamazine (DEC); while this drug does not kill all of the adult worms, it prevents infected people from giving the disease to someone else.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lymphatic filariasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lymphatic filariasis" returned 297 free, full-text research articles on human participants. First 3 results:

Knowledge, attitudes and perceptions regarding lymphatic filariasis: study on systematic noncompliance with mass drug administration.
 

Author(s): Silvia Cabral, Cristine Bonfim, Rosalira Oliveira, Paula Oliveira, Terezinha Guimarães, Eduardo Brandão, Ana Maria Aguiar-Santos, Zulma Medeiros

Journal:

 

The aim of this study was to investigate the epidemiological characteristics, antigenic profile, perceptions, attitudes and practices of individuals who have been systematically non-compliant in mass drug administration (MDA) campaigns targeting lymphatic filariasis, in the municipality ...

Last Updated: 26 Apr 2017

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Reaching endpoints for lymphatic filariasis elimination- results from mass drug administration and nocturnal blood surveys, South Gujarat, India.
 

Author(s): Anjali Modi, Sukesha Gamit, Bharat S Jesalpura, George Kurien, Jayendra K Kosambiya

Journal:

 

Following the World Health Assembly resolution on Elimination of lymphatic filariasis (ELF) as a public health problem by the year 2020, a Global Program (GPELF) was launched in 1997 to help endemic countries to initiate national programs. The current strategy to interrupt transmission ...

Last Updated: 3 Apr 2017

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The Impact of Lymphatic Filariasis Mass Drug Administration Scaling Down on Soil-Transmitted Helminth Control in School-Age Children. Present Situation and Expected Impact from 2016 to 2020.
 

Author(s): Denise Mupfasoni, Antonio Montresor, Alexei Mikhailov, Jonathan King

Journal:

 

Lymphatic filariasis (LF) and soil-transmitted-helminths (STH) are co-endemic in 58 countries which are mostly in Africa and Asia. Worldwide, 486 million school-age children are considered at risk of both diseases. In 2000, the World Health Organization (WHO) established the global ...

Last Updated: 19 Dec 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lymphatic filariasis" returned 33 free, full-text review articles on human participants. First 3 results:

Loa loa vectors Chrysops spp.: perspectives on research, distribution, bionomics, and implications for elimination of lymphatic filariasis and onchocerciasis.
 

Author(s): Louise Kelly-Hope, Rossely Paulo, Brent Thomas, Miguel Brito, Thomas R Unnasch, David Molyneux

Journal:

 

Loiasis is a filarial disease caused Loa loa. The main vectors are Chrysops silacea and C. dimidiata which are confined to the tropical rainforests of Central and West Africa. Loiasis is a mild disease, but individuals with high microfilaria loads may suffer from severe adverse events ...

Last Updated: 6 Apr 2017

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Determinants of parasite drug resistance in human lymphatic filariasis.
 

Author(s): F Cobo

Journal: Rev Esp Quimioter. 2016 Dec;29(6):288-295.

 

Infection with filarial nematodes remains endemic in several countries worldwide and some of these infections are commonly associated with severe disease. The elimination of lymphatic filariasis relies on drug administration using the three drugs currently available for treatment: ...

Last Updated: 18 Nov 2016

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The Effect of Hygiene-Based Lymphedema Management in Lymphatic Filariasis-Endemic Areas: A Systematic Review and Meta-analysis.
 

Author(s): Meredith E Stocks, Matthew C Freeman, David G Addiss

Journal:

 

Lymphedema of the leg and its advanced form, known as elephantiasis, are significant causes of disability and morbidity in areas endemic for lymphatic filariasis (LF), with an estimated 14 million persons affected worldwide. The twin goals of the World Health Organization's Global ...

Last Updated: 27 Oct 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Death to Onchocerciasis and Lymphatic Filariasis (DOLF) Triple Drug Therapy for Lymphatic Filariasis
 

Status: Recruiting

Condition Summary: Lymphatic Filariasis

 

Last Updated: 27 Mar 2017

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Optimization of Mass Drug Administration With Existing Drug Regimens for Lymphatic Filariasis and Onchocerciasis for Ivory Coast (DOLF-Ivory Coast)
 

Status: Recruiting

Condition Summary: Lymphatic Filariasis; Onchocerciasis; Soil Transmitted Helminth (STH) Infections

 

Last Updated: 21 Nov 2016

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Fiji Integrated Therapy (FIT) - Triple Therapy for Lymphatic Filariasis, Scabies and Soil Transmitted Helminths in Fiji
 

Status: Not yet recruiting

Condition Summary: Lymphatic Filariases; Scabies; Impetigo; Soil Transmitted Helminths

 

Last Updated: 2 Jun 2017

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