Lymphatic filariasis

Common Name(s)

Lymphatic filariasis

Lymphatic filariasis is a parasitic disease caused by microscopic, thread-like worms that only live in the human lymph system, which maintains the body's fluid balance and fights infections. It is spread from person to person by mosquitoes. Most infected people are asymptomatic and never develop clinical symptoms. A small percentage of people develop lymphedema, which may affect the legs, arms, breasts, and genitalia; bacterial infections that cause hardening and thickening of the skin, called elephantiasis; hydrocele (swelling of the scrotum) in men; and pulmonary tropical eosinophilia syndrome. Treatment may include a yearly dose of medicine, called diethylcarbamazine (DEC); while this drug does not kill all of the adult worms, it prevents infected people from giving the disease to someone else.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lymphatic filariasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lymphatic filariasis" returned 328 free, full-text research articles on human participants. First 3 results:

Evaluation of the recombinant antigens Wb14 and WbT for the capture antibody diagnosis of lymphatic filariasis.
 

Author(s): André Filipe Pastor, Abraham Rocha, Klécia de Melo Cassemiro, Marli Tenório, Paula Melo, Maria Rosângela Grilis, Maressa Rhuama, Antonio Mauro Rezende, Osvaldo Pompilio de Melo Neto, Ernesto Marques, Rafael Dhalia

Journal:

 

Lymphatic filariasis (LF) is a parasitic disease caused mainly by the Wuchereria bancrofti worm and that affects up to 120 million people worldwide. LF is the second cause of chronic global deformity, responsible for 15 million people with lymphedema (elephantiasis) and 25 million ...

Last Updated: 31 Dec 1969

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Reassessment of areas with persistent Lymphatic Filariasis nine years after cessation of mass drug administration in Sri Lanka.
 

Author(s): Ramakrishna U Rao, Sandhya D Samarasekera, Kumara C Nagodavithana, Tharanga D M Dassanayaka, Manjula W Punchihewa, Udaya S B Ranasinghe, Gary J Weil

Journal:

 

Sri Lanka was one of the first countries to initiate a lymphatic filariasis (LF) elimination program based on WHO guidelines. The Anti-Filariasis Campaign provided 5 annual rounds of mass drug administration (MDA) with diethylcarbamazine plus albendazole in all 8 endemic districts ...

Last Updated: 31 Dec 1969

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Translating Research into Reality: Elimination of Lymphatic Filariasis from Haiti.
 

Author(s): Patrick J Lammie, Mark L Eberhard, David G Addiss, Kimberly Y Won, Madsen Beau de Rochars, Abdel N Direny, Marie Denise Milord, Jack Guy Lafontant, Thomas G Streit

Journal: Am. J. Trop. Med. Hyg.. 2017 Oct;97(4_Suppl):71-75.

 

Research provides the essential foundation of disease elimination programs, including the global program to eliminate lymphatic filariasis (GPELF). The development and validation of new diagnostic tools and intervention strategies, critical steps in the evolution of GPELF, required ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lymphatic filariasis" returned 36 free, full-text review articles on human participants. First 3 results:

A systematic review of factors that shape implementation of mass drug administration for lymphatic filariasis in sub-Saharan Africa.
 

Author(s): Adam Silumbwe, Joseph Mumba Zulu, Hikabasa Halwindi, Choolwe Jacobs, Jessy Zgambo, Rosalia Dambe, Mumbi Chola, Gershom Chongwe, Charles Michelo

Journal:

 

Understanding factors surrounding the implementation process of mass drug administration for lymphatic filariasis (MDA for LF) elimination programmes is critical for successful implementation of similar interventions. The sub-Saharan Africa (SSA) region records the second highest ...

Last Updated: 31 Dec 1969

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Loa loa vectors Chrysops spp.: perspectives on research, distribution, bionomics, and implications for elimination of lymphatic filariasis and onchocerciasis.
 

Author(s): Louise Kelly-Hope, Rossely Paulo, Brent Thomas, Miguel Brito, Thomas R Unnasch, David Molyneux

Journal:

 

Loiasis is a filarial disease caused Loa loa. The main vectors are Chrysops silacea and C. dimidiata which are confined to the tropical rainforests of Central and West Africa. Loiasis is a mild disease, but individuals with high microfilaria loads may suffer from severe adverse events ...

Last Updated: 31 Dec 1969

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Fifteen years of programme implementation for the elimination of Lymphatic Filariasis in Ghana: Impact of MDA on immunoparasitological indicators.
 

Author(s): Nana-Kwadwo Biritwum, Dziedzom K de Souza, Benjamin Marfo, Samuel Odoom, Bright Alomatu, Odame Asiedu, Abednego Yeboah, Tei E Hervie, Ernest O Mensah, Paul Yikpotey, Joseph B Koroma, David Molyneux, Moses J Bockarie, John O Gyapong

Journal:

 

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Prevalence Studies After Triple Drug Therapy for Lymphatic Filariasis
 

Status: Recruiting

Condition Summary: Lymphatic Filariases

 

Last Updated: 1 Feb 2018

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Last Updated: 7 May 2018

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Fiji Integrated Therapy (FIT) - Triple Therapy for Lymphatic Filariasis, Scabies and Soil Transmitted Helminths in Fiji
 

Status: Recruiting

Condition Summary: Lymphatic Filariases; Scabies; Impetigo; Soil Transmitted Helminths

 

Last Updated: 20 Feb 2018

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