Lymphangioma

Common Name(s)

Lymphangioma

Lymphangioma is a benign (non-cancerous) mass made of fluid-filled spaces, which is thought to occur due to abnormal development of the lymphatic system. They are always present at birth, although they may change and become more apparent over time. Lymphangiomas are most commonly found in the head and neck region, but can affect almost any part of the body (except the brain). Some may appear as a tiny blue or red spot while others are massive and affect an entire limb (arm or leg). The signs and symptoms vary depending on the size and location of the mass; however, lymphangiomas can disfigure affected areas and potentially disrupt the function of nearby organs or tissues regardless of size. The exact underlying cause is unknown. Treatment options vary based on the signs and symptoms present in each person but may include surgery.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lymphangioma" for support, advocacy or research.

Lymphangiomatosis & Gorham's Disease Alliance

Our mission is to improve the care of patients through our patient support programs, and by raising funds to support research that will identify effective treatments and cures. We strive to educate patients and families, and the medical and scientific communities, by providing important, relevant information, and by being the leading advocate for the worldwide member-community.

Last Updated: 5 Nov 2012

View Details
Lymphatic Education & Research Network

Our Mission is to fight lymphatic disease and lymphedema through education, research and advocacy. We seek to accelerate the prevention, treatment and cure of the disease while bringing patients and medical professionals together to address the unmet needs surrounding lymphatic disorders.

Last Updated: 14 May 2014

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lymphangioma" for support, advocacy or research.

Lymphangiomatosis & Gorham's Disease Alliance

Our mission is to improve the care of patients through our patient support programs, and by raising funds to support research that will identify effective treatments and cures. We strive to educate patients and families, and the medical and scientific communities, by providing important, relevant information, and by being the leading advocate for the worldwide member-community.

http://www.lgdalliance.org/

Last Updated: 5 Nov 2012

View Details
Lymphatic Education & Research Network

Our Mission is to fight lymphatic disease and lymphedema through education, research and advocacy. We seek to accelerate the prevention, treatment and cure of the disease while bringing patients and medical professionals together to address the unmet needs surrounding lymphatic disorders.

http://www.lymphaticnetwork.org

Last Updated: 14 May 2014

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

General Resources

Lymphatic Malformation Research

The LGDA is closely affiliated with the Lymphatic Malformation Institute (LMI). The LMI receives requests for research projects into lymphatic diseases including lymphangiomatosis and Gorham's disease.

Updated 3 Nov 2012

Open Doc
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lymphangioma" returned 254 free, full-text research articles on human participants. First 3 results:

The use of sirolimus in the treatment of giant cystic lymphangioma: Four case reports and update of medical therapy.
 

Author(s): Ilaria Amodeo, Mariarosa Colnaghi, Genny Raffaeli, Giacomo Cavallaro, Fabrizio Ciralli, Silvana Gangi, Ernesto Leva, Lorenzo Pignataro, Irene Borzani, Lorenza Pugni, Fabio Mosca

Journal: Medicine (Baltimore). 2017 Dec;96(51):e8871.

 

Lymphatic malformations (LMs) are rare and benign anomalies resulting from the defective embryological development of the primordial lymphatic structures. Due to their permeative growth throughout all tissue layers, treatment is often challenging. Small asymptomatic lesions can be ...

Last Updated: 31 Dec 1969

Go To URL
Lymphangioma secondary to irradiation after mastectomy.
 

Author(s): Aline Oliveti, Tatiana Basso Biasi, Gabriella Di Giunta Funchal

Journal: An Bras Dermatol. ;92(3):395-397.

 

Lymphangioma is a rare benign disease of the lymphatic vessels. Typically, they are primary conditions but may be acquired secondarily, such as those caused by irradiation during radiotherapy for the treatment of breast cancer. The local lymphatic obstruction provoked by irradiation ...

Last Updated: 31 Dec 1969

Go To URL
[Lymphangioma of the breast: about a case].
 

Author(s): Eric Mbuya Musapudi, Aimé Lukoba Bwalya, Igor Mujinga Wa Mujinga, Didier Tshibangu Mujinga, Julien Ilunga Nikulu, Guy Nday Ilunga

Journal:

 

Lymphangioma is a benign lesion of the lymphatic vessels. It is a rare paediatric condition and it is exceptional among adults. It mainly occurs in the neck, armpit and abdomen. It rarely occurs in the breast. We report the case of a 18 year-old female patient seen in consultation ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lymphangioma" returned 32 free, full-text review articles on human participants. First 3 results:

Sclerotherapy for Orbital Lymphangioma - Case Series and Literature Review.
 

Author(s): Karnesh Chandrakant Patel, George Kalantzis, Nabil El-Hindy, Bernard Y Chang

Journal: In Vivo. ;31(2):263-266.

 

Orbital lymphangioma is a lymphatic system lesion that commonly presents in childhood. Management of these lesions is complex. Sclerotherapy is a therapy used to treat and shrink lesions prior to or as an alternative to surgery. We present three cases of orbital lymphangioma that ...

Last Updated: 31 Dec 1969

Go To URL
[Cervicothoracic cystic lymphangioma: about a case].
 

Author(s): Karim Nadour, Mountassir Moujahid

Journal:

 

Cervicothoracic cystic lymphangiomas are rare benign tumors developing from sequestration of embryonic lymph sac which is gradually filled with lymph fluid. The diagnosis is based on clinical signs (laterocervical swelling) and imaging (ultrasound and CT scan), then confirmed by histology ...

Last Updated: 31 Dec 1969

Go To URL
[Retroperitoneal cystic lymphangioma: about 5 cases and review of the literature].
 

Author(s): Ahmed Saadi, Haroun Ayed, Omar Karray, Walid Kerkeni, Abderrazak Bouzouita, Mohamed Cherif, Riadh Ben Slama, Amine Derouiche, Mohamed Chebil

Journal:

 

Cystic lymphangioma is a rare, benign malformation of the lymphatic vessels which may be observed on various locations. Retroperitoneal location is less common than mesenteric location. Cystic lymphangioma has a polymorphic clinical presentation. Diagnosis is based on imaging but ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations
 

Status: Not yet recruiting

Condition Summary: Lymphatic Malformation; Pediatric

 

Last Updated: 29 Jan 2018

Go to URL
Sildenafil for the Treatment of Lymphatic Malformations
 

Status: Recruiting

Condition Summary: Lymphatic Malformations; Lymphatic Diseases

 

Last Updated: 13 Mar 2018

Go to URL
Lymphatic Anomalies Registry
 

Status: Recruiting

Condition Summary: Lymphatic Malformation; Generalized Lymphatic Anomaly (GLA); Central Conducting Lymphatic Anomaly; CLOVES Syndrome; Gorham-Stout Disease ("Disappearing Bone Disease"); Blue Rubber Bleb Nevus Syndrome; Kaposiform Lymphangiomatosis; Kaposiform Hemangioendothelioma/Tufted Angioma; Klippel-Trenaunay Syndrome; Lymphangiomatosis

 

Last Updated: 23 Jan 2018

Go to URL