Lymphangioma

Common Name(s)

Lymphangioma

Lymphangioma is a benign (non-cancerous) mass made of fluid-filled spaces, which is thought to occur due to abnormal development of the lymphatic system. They are always present at birth, although they may change and become more apparent over time. Lymphangiomas are most commonly found in the head and neck region, but can affect almost any part of the body (except the brain). Some may appear as a tiny blue or red spot while others are massive and affect an entire limb (arm or leg). The signs and symptoms vary depending on the size and location of the mass; however, lymphangiomas can disfigure affected areas and potentially disrupt the function of nearby organs or tissues regardless of size. The exact underlying cause is unknown. Treatment options vary based on the signs and symptoms present in each person but may include surgery.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lymphangioma" for support, advocacy or research.

Lymphangiomatosis & Gorham's Disease Alliance

Our mission is to improve the care of patients through our patient support programs, and by raising funds to support research that will identify effective treatments and cures. We strive to educate patients and families, and the medical and scientific communities, by providing important, relevant information, and by being the leading advocate for the worldwide member-community.

Last Updated: 5 Nov 2012

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Lymphatic Education & Research Network

Our Mission is to fight lymphatic disease and lymphedema through education, research and advocacy. We seek to accelerate the prevention, treatment and cure of the disease while bringing patients and medical professionals together to address the unmet needs surrounding lymphatic disorders.

Last Updated: 14 May 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lymphangioma" for support, advocacy or research.

Lymphangiomatosis & Gorham's Disease Alliance

Our mission is to improve the care of patients through our patient support programs, and by raising funds to support research that will identify effective treatments and cures. We strive to educate patients and families, and the medical and scientific communities, by providing important, relevant information, and by being the leading advocate for the worldwide member-community.

http://www.lgdalliance.org/

Last Updated: 5 Nov 2012

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Lymphatic Education & Research Network

Our Mission is to fight lymphatic disease and lymphedema through education, research and advocacy. We seek to accelerate the prevention, treatment and cure of the disease while bringing patients and medical professionals together to address the unmet needs surrounding lymphatic disorders.

http://www.lymphaticnetwork.org

Last Updated: 14 May 2014

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General Support Organizations

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General Resources

Lymphatic Malformation Research

The LGDA is closely affiliated with the Lymphatic Malformation Institute (LMI). The LMI receives requests for research projects into lymphatic diseases including lymphangiomatosis and Gorham's disease.

Updated 3 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lymphangioma" returned 188 free, full-text research articles on human participants. First 3 results:

Cutaneous Lymphangioma circumscriptum - dermoscopic features.
 

Author(s): António Fernandes Massa, Nuno Menezes, Armando Baptista, Ana Isabel Moreira, Eduarda Osório Ferreira

Journal: An Bras Dermatol. ;90(2):262-4.

 

Lymphangiomas are congenital lymphatic malformations and cutaneous lymphangioma circumscriptum is the most common type. It is clinically characterized by clusters of translucent vesicles and the presence of dermoscopically yellow lacunae surrounded by pale septa, as well as reddish ...

Last Updated: 2 Apr 2015

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Abdominal cystic lymphangioma complicated by mesenteric volvulus: a case report.
 

Author(s): Ben Hassine Lilia, Kharrat Rym, Ghribi Ali, Fitouri Fatma, Louati Héla, Douira Wièm, Lahmar Lilia, Bellagha Ibtissem, Hamzaoui Mourad

Journal: Tunis Med. 2014 May;92(5):356-8.

 

Last Updated: 16 Dec 2014

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Klippel-Trenaunay syndrome presenting with acanthocytosis and splenic and retroperitoneal lymphangioma: a case report.
 

Author(s): Milinda Withana, Chaturaka Rodrigo, Mitrakrishnan Chrishan Shivanthan, Sachini Warnakulasooriya, Manu Wimalachandra, Lallindra Gooneratne, Senaka Rajapakse

Journal:

 

Klippel-Trenaunay syndrome is a rare congenital mesodermal abnormality characterized by bone and soft tissue hypertrophy, extensive hemangioma and venous abnormalities. We report the case of a patient with two additional rare clinical manifestations in the background of Klippel-Trenaunay ...

Last Updated: 10 Dec 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lymphangioma" returned 20 free, full-text review articles on human participants. First 3 results:

Cystic lymphangioma of adrenal gland: a clinicopathological study of 3 cases and review of literature.
 

Author(s): Ming Zhao, Qianfeng Gu, Changshui Li, Jingjing Yu, Honggang Qi

Journal:

 

Cystic lymphangioma of the adrenal gland is a rare and benign lesion, most often found incidentally during abdominal imaging studies, abdominal surgery or at autopsy. We aimed to retrospectively review all adrenal lymphangioma cases at our hospital, further document their lymphatic ...

Last Updated: 8 Sep 2014

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Lymphangioma of the ileocecal valve clinically masquerading as a submucosal small intestinal GIST: report of a case and literature review.
 

Author(s): Omar A Al-Obeed, Maha-Hamadien Abdulla

Journal: Saudi J Gastroenterol. ;20(4):262-4.

 

Lymphangiomas are rare tumors affecting the gastrointestinal tract, and may be seen in the bowel, gall bladder, and pancreas. They resemble hemangiomas, but consist of spaces of variable sizes containing lymph. In this report, we describe the case of a 53-year-old male who presented ...

Last Updated: 19 Jul 2014

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Lymphangioma-like Kaposi sarcoma of the oral mucosa.
 

Author(s): Pavithra Pugalagiri, Susan Muller, Darren P Cox, Harvey P Kessler, John M Wright, Yi-Shing L Cheng

Journal: Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Jul;116(1):84-90.

 

With the epidemic of acquired immunodeficiency syndrome, the clinical and histopathological features of Kaposi sarcoma (KS) became routine for most practicing surgical pathologists. The histological spectrum of KS broadened significantly over time and today a wide variety of rare ...

Last Updated: 17 Jun 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Lymphatic Anomalies Registry
 

Status: Recruiting

Condition Summary: Lymphatic Malformation; Generalized Lymphatic Anomaly (GLA); Central Conducting Lymphatic Anomaly; CLOVES Syndrome; Gorham-Stout Disease ("Disappearing Bone Disease"); Blue Rubber Bleb Nevus Syndrome; Kaposiform Lymphangiomatosis; Kaposiform Hemangioendothelioma/Tufted Angioma; Klippel-Trenaunay Syndrome; Lymphangiomatosis

 

Last Updated: 21 Mar 2015

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Characterization of the Pathogenesis of Primary and Secondary Lymphatic Disorders
 

Status: Recruiting

Condition Summary: Lymphangiomatosis; Lymphedema; Lymphangiectasia; Pulmonary Lymphangiectasia

 

Last Updated: 2 May 2015

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