Lymphangioma

Common Name(s)

Lymphangioma

Lymphangioma is a benign (non-cancerous) mass made of fluid-filled spaces, which is thought to occur due to abnormal development of the lymphatic system. They are always present at birth, although they may change and become more apparent over time. Lymphangiomas are most commonly found in the head and neck region, but can affect almost any part of the body (except the brain). Some may appear as a tiny blue or red spot while others are massive and affect an entire limb (arm or leg). The signs and symptoms vary depending on the size and location of the mass; however, lymphangiomas can disfigure affected areas and potentially disrupt the function of nearby organs or tissues regardless of size. The exact underlying cause is unknown. Treatment options vary based on the signs and symptoms present in each person but may include surgery.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lymphangioma" for support, advocacy or research.

Lymphangiomatosis & Gorham's Disease Alliance

Our mission is to improve the care of patients through our patient support programs, and by raising funds to support research that will identify effective treatments and cures. We strive to educate patients and families, and the medical and scientific communities, by providing important, relevant information, and by being the leading advocate for the worldwide member-community.

Last Updated: 5 Nov 2012

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Lymphatic Education & Research Network

Our Mission is to fight lymphatic disease and lymphedema through education, research and advocacy. We seek to accelerate the prevention, treatment and cure of the disease while bringing patients and medical professionals together to address the unmet needs surrounding lymphatic disorders.

Last Updated: 14 May 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lymphangioma" for support, advocacy or research.

Lymphangiomatosis & Gorham's Disease Alliance

Our mission is to improve the care of patients through our patient support programs, and by raising funds to support research that will identify effective treatments and cures. We strive to educate patients and families, and the medical and scientific communities, by providing important, relevant information, and by being the leading advocate for the worldwide member-community.

http://www.lgdalliance.org/

Last Updated: 5 Nov 2012

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Lymphatic Education & Research Network

Our Mission is to fight lymphatic disease and lymphedema through education, research and advocacy. We seek to accelerate the prevention, treatment and cure of the disease while bringing patients and medical professionals together to address the unmet needs surrounding lymphatic disorders.

http://www.lymphaticnetwork.org

Last Updated: 14 May 2014

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General Support Organizations

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General Resources

Lymphatic Malformation Research

The LGDA is closely affiliated with the Lymphatic Malformation Institute (LMI). The LMI receives requests for research projects into lymphatic diseases including lymphangiomatosis and Gorham's disease.

Updated 3 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lymphangioma" returned 247 free, full-text research articles on human participants. First 3 results:

Laparoscopic Treatment of Intraabdominal Cystic Lymphangioma.
 

Author(s): Eugen Târcoveanu, Radu Moldovanu, Costel Bradea, Nutu Vlad, Delia Ciobanu, Alin Vasilescu

Journal: Chirurgia (Bucur). ;111(3):236-41.

 

The abdominal cystic lymphangioma (CL) in adults is a rare benign tumor of the lymphatic system.

Last Updated: 25 Jul 2016

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[A Case of Cavernous Lymphangioma of the Small Bowel Mesentery].
 

Author(s): In Taik Hong, Jae Myung Cha, Joung Il Lee, Kwang Ro Joo, Il Hyun Baek, Hyun Phil Shin, Jung Won Jeon, Jun Uk Lim

Journal: Korean J Gastroenterol. 2015 Sep;66(3):172-5.

 

Lymphangioma is a benign vascular lesion with characteristics of subepithelial tumor which can proliferate in the lymphatic system. Lymphangioma of the small-bowel mesentery is rare, having been reported in less than 2% of all lymphangiomas. Lymphangioma does not require any specific ...

Last Updated: 21 Sep 2015

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Adult cervical lymphangioma - ultrasonography, surgical removal, and pathology results. Case report.
 

Author(s): Adrian Costache, Mihai Dumitru, Daniel Tweedie, Codrut Sarafoleanu, Ion Anghel

Journal: Med Ultrason. 2015 Sep;17(3):411-3.

 

Lymphangioma is a rare pathology in children and even more exotic when encountered in adults. We review the current data on this subject underlining possible controversies and limitations. This is the case of an adult male who underwent a complete clinical examination and ENT performed ...

Last Updated: 7 Sep 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lymphangioma" returned 27 free, full-text review articles on human participants. First 3 results:

Laparoscopic resection of retroperitoneal lymphangioma around the pancreas: a case report and review of the literature.
 

Author(s): Takafumi Sato, Yoichi Matsuo, Kazuyoshi Shiga, Kenta Saito, Mamoru Morimoto, Hirotaka Miyai, Hiromitsu Takeyama

Journal:

 

Lymphangiomas are rare, benign tumors. An intra-abdominal location of these lesions is rarer still and there are only a few reports describing laparoscopic resection for retroperitoneal lymphangiomas, especially in tumors that mimic pancreatic tumors.

Last Updated: 15 Dec 2015

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Cystic lymphangioma of the adrenal gland: report of a case and review of the literature.
 

Author(s): Gaëtan-Romain Joliat, Emmanuel Melloul, Reza Djafarrian, Sabine Schmidt, Sara Fontanella, Pu Yan, Nicolas Demartines, Nermin Halkic

Journal:

 

Cystic lymphangioma is a rare tumor of the lymphatic vessels that occurs more frequently in women. Location of this pathology can be diverse but most commonly occurs in the neck or axilla. Cystic lymphangioma originating from the adrenal tissue represents a very rare entity.

Last Updated: 19 Apr 2015

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Giant fetal lymphangioma at chest wall and prognosis: case report and literature review.
 

Author(s): Donghao Lu, Yuhe Wang, Weiyue Zeng, Bing Peng

Journal: Taiwan J Obstet Gynecol. 2015 Feb;54(1):62-5.

 

To report a rare liveborn case with a giant, septated, chest wall lymphangioma that underwent prenatal expectation treatment.

Last Updated: 14 Feb 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Sildenafil for the Treatment of Lymphatic Malformations
 

Status: Recruiting

Condition Summary: Lymphatic Malformations; Lymphatic Diseases

 

Last Updated: 12 Apr 2016

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Lymphatic Anomalies Registry
 

Status: Recruiting

Condition Summary: Lymphatic Malformation; Generalized Lymphatic Anomaly (GLA); Central Conducting Lymphatic Anomaly; CLOVES Syndrome; Gorham-Stout Disease ("Disappearing Bone Disease"); Blue Rubber Bleb Nevus Syndrome; Kaposiform Lymphangiomatosis; Kaposiform Hemangioendothelioma/Tufted Angioma; Klippel-Trenaunay Syndrome; Lymphangiomatosis

 

Last Updated: 26 Jul 2016

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Characterization of the Pathogenesis of Primary and Secondary Lymphatic Disorders
 

Status: Recruiting

Condition Summary: Lymphangiomatosis; Lymphedema; Lymphangiectasia; Pulmonary Lymphangiectasia

 

Last Updated: 31 Aug 2016

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