Lupus

Common Name(s)

Lupus

Lupus is an autoimmune disease. It can affect almost every organ in the body. Symptoms of lupus can be very mild to life threatening. There are three types of lupus; systemic lupus erythematosus, discoid lupus, and drug-induced lupus. Treatment of lupus depends on the severity of the condition and what parts of the body are affected. Treatment may include acetaminophen, ibuprofen, antimalarial drugs, anti-inflammatory steroids, and/or immunosuppressive drugs.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lupus" for support, advocacy or research.

Lupus Foundation of America, Inc.

The Lupus Foundation of America is the only national force devoted to solving the mystery of lupus, one of the world’s cruelest, most unpredictable, and devastating diseases, while giving caring support to those who suffer from its brutal impact. Through a comprehensive program of research, education, and advocacy, we lead the fight to improve the quality of life for all people affected by lupus.

Last Updated: 20 May 2013

View Details
APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

Last Updated: 12 Aug 2013

View Details
Logo
Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

Last Updated: 11 Jul 2016

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

View Details
Xeroderma Pigmentosum Society, Inc.

The XP Society mission includes education, protection, and research for a cure for patients with XP and all severe life-threatening UV sensitivity disorders.

Last Updated: 2 Dec 2009

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lupus" for support, advocacy or research.

Lupus Foundation of America, Inc.

The Lupus Foundation of America is the only national force devoted to solving the mystery of lupus, one of the world’s cruelest, most unpredictable, and devastating diseases, while giving caring support to those who suffer from its brutal impact. Through a comprehensive program of research, education, and advocacy, we lead the fight to improve the quality of life for all people affected by lupus.

http://www.lupus.org

Last Updated: 20 May 2013

View Details
APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

http://www.apsfa.org

Last Updated: 12 Aug 2013

View Details
Logo
Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

http://www.bensfriends.org

Last Updated: 11 Jul 2016

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

View Details
Xeroderma Pigmentosum Society, Inc.

The XP Society mission includes education, protection, and research for a cure for patients with XP and all severe life-threatening UV sensitivity disorders.

http://www.xps.org

Last Updated: 2 Dec 2009

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

General Resources

Handout on Health: Systemic Lupus Erythematosus

This booklet is for people who have systemic lupus erythematosus, commonly called SLE or lupus, as well as for their family and friends and others who want to better understand the disease. The booklet describes the disease and its symptoms and conta

Updated 13 Nov 2012

Go To URL
APS Foundation of America, Inc Fan Page

The APS Foundation of America, Inc. is the leading United States nonprofit health agency dedicated to bringing national awareness to Antiphospholipid Antibody Syndrome (APS).

Updated 13 Nov 2012

Go To URL
 
 
Top

Blogs

APS Friends & Support Forum

Are you looking for Support for Antiphospholipid Antibody Syndrome, APS, APLS, APLA, Hughes Syndrome, or Sticky Blood? Well you've come to the right place! This is an private forum for people who have Antiphospholipid Antibody Syndrome, friends, fam

Updated 13 Nov 2012

Go To URL
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lupus" returned 6579 free, full-text research articles on human participants. First 3 results:

Effects of a spleen tyrosine kinase inhibitor on progression of the lupus nephritis in mice.
 

Author(s): Maki Kitai, Noboru Fukuda, Takahiro Ueno, Morito Endo, Takashi Maruyama, Masanori Abe, Kazuyoshi Okada, Masayoshi Soma, Koichi Matsumoto

Journal: J. Pharmacol. Sci.. 2017 May;134(1):29-36.

 

The Fc receptors (FcR) have pivotal roles in the pathogenesis of the autoimmune glomerulonephritis. We therefore investigated the effects of a Syk inhibitor on the progression of lupus nephritis and SH3 domain binding protein 2 and p38MAP kinase signalings in mice. NZB/W F1 mice, ...

Last Updated: 8 May 2017

Go To URL
Association of novel polymorphisms in TMEM39A gene with systemic lupus erythematosus in a Chinese Han population.
 

Author(s): Xinze Cai, Wenyue Huang, Xudong Liu, Lining Wang, Yi Jiang

Journal:

 

This study aimed to assess the association between 14 single nucleotide polymorphisms (SNPs) in six genes (IRF8, TMEM39A, IKZF3, ORMDL3, GSDMB, and ZPBP2) and systemic lupus erythematosus (SLE) in a Chinese Han population sample.

Last Updated: 21 Apr 2017

Go To URL
Voice disorder in systemic lupus erythematosus.
 

Author(s): Milena S F C de Macedo, Kauê M Costa, Manoel da Silva Filho

Journal:

 

Systemic lupus erythematosus (SLE) is a chronic disease characterized by progressive tissue damage. In recent decades, novel treatments have greatly extended the life span of SLE patients. This creates a high demand for identifying the overarching symptoms associated with SLE and ...

Last Updated: 17 Apr 2017

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lupus" returned 808 free, full-text review articles on human participants. First 3 results:

The value of repeat biopsy in lupus nephritis flares.
 

Author(s): Javier Narváez, Milagros Ricse, Montserrat Gomà, Francesca Mitjavila, Xavier Fulladosa, Olga Capdevila, Joan Torras, Xavier Juanola, Ramón Pujol-Farriols, Joan Miquel Nolla

Journal: Medicine (Baltimore). 2017 Jun;96(24):e7099.

 

Whether a repeat renal biopsy is helpful during lupus nephritis (LN) flares remains debatable. In order to analyze the clinical utility of repeat renal biopsy in this complex situation, we retrospectively reviewed our series of 54 LN patients who had one or more repeat biopsies performed ...

Last Updated: 14 Jun 2017

Go To URL
Pathways leading to an immunological disease: systemic lupus erythematosus.
 

Author(s): Olga Zharkova, Teja Celhar, Petra D Cravens, Anne B Satterthwaite, Anna-Marie Fairhurst, Laurie S Davis

Journal: Rheumatology (Oxford). 2017 Apr;56(suppl_1):i55-i66.

 

SLE is a chronic autoimmune disease caused by perturbations of the immune system. The clinical presentation is heterogeneous, largely because of the multiple genetic and environmental factors that contribute to disease initiation and progression. Over the last 60 years, there have ...

Last Updated: 4 Apr 2017

Go To URL
Extracellular Vesicles as Therapeutic Agents in Systemic Lupus Erythematosus.
 

Author(s): Javier Perez-Hernandez, Josep Redon, Raquel Cortes

Journal:

 

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease that affects multiple organs. Currently, therapeutic molecules present adverse side effects and are only effective in some SLE patient subgroups. Extracellular vesicles (EV), including exosomes, microvesicles ...

Last Updated: 28 Mar 2017

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Duke Lupus Registry
 

Status: Recruiting

Condition Summary: Systemic Lupus Erythematosus; Cutaneous Lupus

 

Last Updated: 21 Nov 2016

Go to URL
Efficacy of 595 nm Pulsed-dye Laser in Treatment of Discoid Lupus Erythematosus
 

Status: Recruiting

Condition Summary: Lupus Erythematosus, Discoid

 

Last Updated: 5 Jun 2017

Go to URL