Lupus

Common Name(s)

Lupus

Lupus is an autoimmune disease. It can affect almost every organ in the body. Symptoms of lupus can be very mild to life threatening. There are three types of lupus; systemic lupus erythematosus, discoid lupus, and drug-induced lupus. Treatment of lupus depends on the severity of the condition and what parts of the body are affected. Treatment may include acetaminophen, ibuprofen, antimalarial drugs, anti-inflammatory steroids, and/or immunosuppressive drugs.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lupus" for support, advocacy or research.

Lupus Foundation of America, Inc.

The Lupus Foundation of America is the only national force devoted to solving the mystery of lupus, one of the world’s cruelest, most unpredictable, and devastating diseases, while giving caring support to those who suffer from its brutal impact. Through a comprehensive program of research, education, and advocacy, we lead the fight to improve the quality of life for all people affected by lupus.

Last Updated: 20 May 2013

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APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

Last Updated: 12 Aug 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 3 Oct 2013

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Xeroderma Pigmentosum Society, Inc.

The XP Society mission includes education, protection, and research for a cure for patients with XP and all severe life-threatening UV sensitivity disorders.

Last Updated: 2 Dec 2009

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lupus" for support, advocacy or research.

Lupus Foundation of America, Inc.

The Lupus Foundation of America is the only national force devoted to solving the mystery of lupus, one of the world’s cruelest, most unpredictable, and devastating diseases, while giving caring support to those who suffer from its brutal impact. Through a comprehensive program of research, education, and advocacy, we lead the fight to improve the quality of life for all people affected by lupus.

http://www.lupus.org

Last Updated: 20 May 2013

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APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

http://www.apsfa.org

Last Updated: 12 Aug 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 3 Oct 2013

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Xeroderma Pigmentosum Society, Inc.

The XP Society mission includes education, protection, and research for a cure for patients with XP and all severe life-threatening UV sensitivity disorders.

http://www.xps.org

Last Updated: 2 Dec 2009

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General Support Organizations

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General Resources

Handout on Health: Systemic Lupus Erythematosus

This booklet is for people who have systemic lupus erythematosus, commonly called SLE or lupus, as well as for their family and friends and others who want to better understand the disease. The booklet describes the disease and its symptoms and conta

Updated 13 Nov 2012

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APS Foundation of America, Inc Fan Page

The APS Foundation of America, Inc. is the leading United States nonprofit health agency dedicated to bringing national awareness to Antiphospholipid Antibody Syndrome (APS).

Updated 13 Nov 2012

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Blogs

APS Friends & Support Forum

Are you looking for Support for Antiphospholipid Antibody Syndrome, APS, APLS, APLA, Hughes Syndrome, or Sticky Blood? Well you've come to the right place! This is an private forum for people who have Antiphospholipid Antibody Syndrome, friends, fam

Updated 13 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lupus" returned 5371 free, full-text research articles on human participants. First 3 results:

Educational and vocational outcomes of adults with childhood- and adult-onset systemic lupus erythematosus: nine years of followup.
 

Author(s): Erica F Lawson, Aimee O Hersh, Laura Trupin, Emily von Scheven, Megumi J Okumura, Jinoos Yazdany, Edward H Yelin

Journal: Arthritis Care Res (Hoboken). 2014 May;66(5):717-24.

 

To compare educational and vocational outcomes among adults with childhood-onset systemic lupus erythematosus (SLE) and adult-onset SLE.

Last Updated: 29 May 2014

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Systemic lupus erythematosus in males: a case series.
 

Author(s): Krishna Kumar Agrawaal, Subodh Sagar Dhakal

Journal: Saudi J Kidney Dis Transpl. 2014 May;25(3):638-42.

 

The reported prevalence of systemic lupus erythematosus (SLE) in the general population is 20-150 cases per 100,000 population. The female to male ratio ranges from 7-15:1. An estrogen effect has been suggested by a number of observations for this difference. In children, sex hormonal ...

Last Updated: 13 May 2014

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Tubulo-reticular inclusions in lupus nephritis: are they relevant?
 

Author(s): Hala Kfoury

Journal: Saudi J Kidney Dis Transpl. 2014 May;25(3):539-43.

 

Tubulo-reticular inclusions (TRIs) are organized subcellular structures that may be found in endothelial cells of patients with systemic lupus erythematosus (SLE). This study was conducted to determine the presence or absence of TRIs and their correlation with the activity index (AI) ...

Last Updated: 13 May 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lupus" returned 606 free, full-text review articles on human participants. First 3 results:

Type I interferon signature in systemic lupus erythematosus.
 

Author(s): Shira Bezalel, Keren Mahlab Guri, Daniel Elbirt, Ilan Asher, Zev Moshe Sthoeger

Journal: Isr. Med. Assoc. J.. 2014 Apr;16(4):246-9.

 

Type I interferons (IFN) are primarily regarded as an inhibitor of viral replication. However, type I IFN, mainly IFNalpha, plays a major role in activation of both the innate and adaptive immune systems. Systemic lupus erythematosus (SLE) is a chronic, multi-systemic, inflammatory ...

Last Updated: 19 May 2014

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Treat-to-target in systemic lupus erythematosus: recommendations from an international task force.
 

Author(s): Ronald F van Vollenhoven, Marta Mosca, George Bertsias, David Isenberg, Annegret Kuhn, Kirsten Lerstrøm, Martin Aringer, Hendrika Bootsma, Dimitrios Boumpas, Ian N Bruce, Ricard Cervera, Ann Clarke, Nathalie Costedoat-Chalumeau, László Czirják, Ronald Derksen, Thomas Dörner, Caroline Gordon, Winfried Graninger, Frédéric Houssiau, Murat Inanc, Søren Jacobsen, David Jayne, Anna Jedryka-Goral, Adrian Levitsky, Roger Levy, Xavier Mariette, Eric Morand, Sandra Navarra, Irmgard Neumann, Anisur Rahman, Jozef Rovensky, Josef Smolen, Carlos Vasconcelos, Alexandre Voskuyl, Anne Voss, Helena Zakharova, Asad Zoma, Matthias Schneider

Journal: Ann. Rheum. Dis.. 2014 Jun;73(6):958-67.

 

The principle of treating-to-target has been successfully applied to many diseases outside rheumatology and more recently to rheumatoid arthritis. Identifying appropriate therapeutic targets and pursuing these systematically has led to improved care for patients with these diseases ...

Last Updated: 5 May 2014

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Managing lupus patients during pregnancy.
 

Author(s): Aisha Lateef, Michelle Petri

Journal: Best Pract Res Clin Rheumatol. 2013 Jun;27(3):435-47.

 

Systemic lupus erythematosus (SLE) is an auto-immune disease, primarily affecting young females. Pregnancy in a woman with SLE remains a high-risk situation with higher maternal and foetal mortality and morbidity. Although live births are achieved in majority of the pregnancies, active ...

Last Updated: 18 Nov 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety Study of AMG 811 in Subjects With Discoid Lupus Erythematosus
 

Status: Recruiting

Condition Summary: Cutaneous Lupus; Discoid Lupus; Lupus; Systemic Lupus Erythematosus

 

Last Updated: 12 Jul 2012

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A Non-drug Study Profiling Cutaneous Lupus
 

Status: Recruiting

Condition Summary: Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Lupus Erythematosus, Discoid

 

Last Updated: 15 Jul 2014

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A Study of Skin and Systemic Biomarkers In Patients With Active Cutaneous Lupus Erythematosus And In Healthy Volunteers
 

Status: Recruiting

Condition Summary: Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Lupus Erythematosus, Discoid; Healthy

 

Last Updated: 16 Jul 2014

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