Lupus

Common Name(s)

Lupus

Lupus is an autoimmune disease. It can affect almost every organ in the body. Symptoms of lupus can be very mild to life threatening. There are three types of lupus; systemic lupus erythematosus, discoid lupus, and drug-induced lupus. Treatment of lupus depends on the severity of the condition and what parts of the body are affected. Treatment may include acetaminophen, ibuprofen, antimalarial drugs, anti-inflammatory steroids, and/or immunosuppressive drugs.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lupus" for support, advocacy or research.

Lupus Foundation of America, Inc.

The Lupus Foundation of America is the only national force devoted to solving the mystery of lupus, one of the world’s cruelest, most unpredictable, and devastating diseases, while giving caring support to those who suffer from its brutal impact. Through a comprehensive program of research, education, and advocacy, we lead the fight to improve the quality of life for all people affected by lupus.

Last Updated: 20 May 2013

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APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

Last Updated: 12 Aug 2013

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Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

Last Updated: 11 Jul 2016

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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Xeroderma Pigmentosum Society, Inc.

The XP Society mission includes education, protection, and research for a cure for patients with XP and all severe life-threatening UV sensitivity disorders.

Last Updated: 2 Dec 2009

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lupus" for support, advocacy or research.

Lupus Foundation of America, Inc.

The Lupus Foundation of America is the only national force devoted to solving the mystery of lupus, one of the world’s cruelest, most unpredictable, and devastating diseases, while giving caring support to those who suffer from its brutal impact. Through a comprehensive program of research, education, and advocacy, we lead the fight to improve the quality of life for all people affected by lupus.

http://www.lupus.org

Last Updated: 20 May 2013

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APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

http://www.apsfa.org

Last Updated: 12 Aug 2013

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Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

http://www.bensfriends.org

Last Updated: 11 Jul 2016

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

View Details
Xeroderma Pigmentosum Society, Inc.

The XP Society mission includes education, protection, and research for a cure for patients with XP and all severe life-threatening UV sensitivity disorders.

http://www.xps.org

Last Updated: 2 Dec 2009

View Details

 

General Support Organizations

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General Resources

Handout on Health: Systemic Lupus Erythematosus

This booklet is for people who have systemic lupus erythematosus, commonly called SLE or lupus, as well as for their family and friends and others who want to better understand the disease. The booklet describes the disease and its symptoms and conta

Updated 13 Nov 2012

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APS Foundation of America, Inc Fan Page

The APS Foundation of America, Inc. is the leading United States nonprofit health agency dedicated to bringing national awareness to Antiphospholipid Antibody Syndrome (APS).

Updated 13 Nov 2012

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Blogs

APS Friends & Support Forum

Are you looking for Support for Antiphospholipid Antibody Syndrome, APS, APLS, APLA, Hughes Syndrome, or Sticky Blood? Well you've come to the right place! This is an private forum for people who have Antiphospholipid Antibody Syndrome, friends, fam

Updated 13 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lupus" returned 6505 free, full-text research articles on human participants. First 3 results:

Association of novel polymorphisms in TMEM39A gene with systemic lupus erythematosus in a Chinese Han population.
 

Author(s): Xinze Cai, Wenyue Huang, Xudong Liu, Lining Wang, Yi Jiang

Journal:

 

This study aimed to assess the association between 14 single nucleotide polymorphisms (SNPs) in six genes (IRF8, TMEM39A, IKZF3, ORMDL3, GSDMB, and ZPBP2) and systemic lupus erythematosus (SLE) in a Chinese Han population sample.

Last Updated: 21 Apr 2017

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Voice disorder in systemic lupus erythematosus.
 

Author(s): Milena S F C de Macedo, Kauê M Costa, Manoel da Silva Filho

Journal:

 

Systemic lupus erythematosus (SLE) is a chronic disease characterized by progressive tissue damage. In recent decades, novel treatments have greatly extended the life span of SLE patients. This creates a high demand for identifying the overarching symptoms associated with SLE and ...

Last Updated: 17 Apr 2017

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Excess atherosclerosis in systemic lupus erythematosus,-A matter of renal involvement: Case control study of 281 SLE patients and 281 individually matched population controls.
 

Author(s): Johanna T Gustafsson, Marie Herlitz Lindberg, Iva Gunnarsson, Susanne Pettersson, Kerstin Elvin, John Öhrvik, Anders Larsson, Kerstin Jensen-Urstad, Elisabet Svenungsson

Journal:

 

Systemic lupus erythematosus (SLE), is a heterogeneous disease which predominantly affects young females (90%). SLE is associated with a shorter life expectancy than in the general population. Standardized mortality ratios (SMR) of 2.4 have been reported, which is comparable to diabetes. ...

Last Updated: 17 Apr 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lupus" returned 793 free, full-text review articles on human participants. First 3 results:

Extracellular Vesicles as Therapeutic Agents in Systemic Lupus Erythematosus.
 

Author(s): Javier Perez-Hernandez, Josep Redon, Raquel Cortes

Journal:

 

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease that affects multiple organs. Currently, therapeutic molecules present adverse side effects and are only effective in some SLE patient subgroups. Extracellular vesicles (EV), including exosomes, microvesicles ...

Last Updated: 28 Mar 2017

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Spotlight on blisibimod and its potential in the treatment of systemic lupus erythematosus: evidence to date.
 

Author(s): Aleksander Lenert, Timothy B Niewold, Petar Lenert

Journal:

 

B cells in general and BAFF (B cell activating factor of the tumor necrosis factor [TNF] family) in particular have been primary targets of recent clinical trials in systemic lupus erythematosus (SLE). In 2011, belimumab, a monoclonal antibody against BAFF, became the first biologic ...

Last Updated: 23 Mar 2017

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Regulation of T Cell Activation and Differentiation by Extracellular Vesicles and Their Pathogenic Role in Systemic Lupus Erythematosus and Multiple Sclerosis.
 

Author(s): Cristina Ulivieri, Cosima T Baldari

Journal:

 

How autoreactive tissue-infiltrated effector T cells are induced and sustained in autoimmune disease, usually dominated by the Th1 and Th17 subsets, is still largely unknown. In organ-specific autoimmunity, self-reactive T cells initially activated by dendritic cells (DCs) in the ...

Last Updated: 3 Feb 2017

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Duke Lupus Registry
 

Status: Recruiting

Condition Summary: Systemic Lupus Erythematosus; Cutaneous Lupus

 

Last Updated: 21 Nov 2016

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Study to Determine if Gardasil Vaccine is Safe and Effective in Lupus Patients
 

Status: Recruiting

Condition Summary: Systemic Lupus Erythematosus

 

Last Updated: 8 Jun 2015

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