Lupus

Common Name(s)

Lupus

Lupus is an autoimmune disease. It can affect almost every organ in the body. Symptoms of lupus can be very mild to life threatening. There are three types of lupus; systemic lupus erythematosus, discoid lupus, and drug-induced lupus. Treatment of lupus depends on the severity of the condition and what parts of the body are affected. Treatment may include acetaminophen, ibuprofen, antimalarial drugs, anti-inflammatory steroids, and/or immunosuppressive drugs.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lupus" for support, advocacy or research.

Lupus Foundation of America, Inc.

The Lupus Foundation of America is the only national force devoted to solving the mystery of lupus, one of the world’s cruelest, most unpredictable, and devastating diseases, while giving caring support to those who suffer from its brutal impact. Through a comprehensive program of research, education, and advocacy, we lead the fight to improve the quality of life for all people affected by lupus.

Last Updated: 20 May 2013

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APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

Last Updated: 12 Aug 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 27 Apr 2015

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Xeroderma Pigmentosum Society, Inc.

The XP Society mission includes education, protection, and research for a cure for patients with XP and all severe life-threatening UV sensitivity disorders.

Last Updated: 2 Dec 2009

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lupus" for support, advocacy or research.

Lupus Foundation of America, Inc.

The Lupus Foundation of America is the only national force devoted to solving the mystery of lupus, one of the world’s cruelest, most unpredictable, and devastating diseases, while giving caring support to those who suffer from its brutal impact. Through a comprehensive program of research, education, and advocacy, we lead the fight to improve the quality of life for all people affected by lupus.

http://www.lupus.org

Last Updated: 20 May 2013

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APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

http://www.apsfa.org

Last Updated: 12 Aug 2013

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 27 Apr 2015

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Xeroderma Pigmentosum Society, Inc.

The XP Society mission includes education, protection, and research for a cure for patients with XP and all severe life-threatening UV sensitivity disorders.

http://www.xps.org

Last Updated: 2 Dec 2009

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General Support Organizations

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General Resources

Handout on Health: Systemic Lupus Erythematosus

This booklet is for people who have systemic lupus erythematosus, commonly called SLE or lupus, as well as for their family and friends and others who want to better understand the disease. The booklet describes the disease and its symptoms and conta

Updated 13 Nov 2012

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APS Foundation of America, Inc Fan Page

The APS Foundation of America, Inc. is the leading United States nonprofit health agency dedicated to bringing national awareness to Antiphospholipid Antibody Syndrome (APS).

Updated 13 Nov 2012

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Blogs

APS Friends & Support Forum

Are you looking for Support for Antiphospholipid Antibody Syndrome, APS, APLS, APLA, Hughes Syndrome, or Sticky Blood? Well you've come to the right place! This is an private forum for people who have Antiphospholipid Antibody Syndrome, friends, fam

Updated 13 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lupus" returned 5592 free, full-text research articles on human participants. First 3 results:

Inflammatory cytokine kinetics to single bouts of acute moderate and intense aerobic exercise in women with active and inactive systemic lupus erythematosus.
 

Author(s): L A Perandini, D Sales-de-Oliveira, Sbv Mello, N O Camara, F B Benatti, F R Lima, E Borba, E Bonfa, H Roschel, A L Sá-Pinto, B Gualano

Journal: Exerc Immunol Rev. 2015 ;21():174-85.

 

The aim of this study was to evaluate changes in the cytokines INF-γ, IL-10, IL-6, TNF-α and soluble TNF receptors (sTNFR1 and sTNFR2) in response to single bouts of acute moderate and intense exercise in systemic lupus erythematosus women with active (SLE(ACTIVE)) and inactive ...

Last Updated: 1 Apr 2015

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Acute transverse myelitis as the first clinical manifestation of systemic lupus erythematosus.
 

Author(s): Aleksandra Loster-Niewinska, Justyna Chojdak-Lukasiewicz, Marek Sasiadek, Magdalena Szmyrka-Kaczmarek, Boguslaw Paradowski

Journal: Neurol India. ;62(6):712-3.

 

Last Updated: 16 Jan 2015

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Systemic lupus erythematosus and subarachnoid hemorrhage.
 

Author(s): Hasan Hüseyin Kozak, Muazzez Betigül Yürüten Çorbacıoğlu, Süleyman Ömer Anlıaçık

Journal: Neurol India. ;62(6):689-90.

 

Last Updated: 16 Jan 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lupus" returned 649 free, full-text review articles on human participants. First 3 results:

Neuropsychiatric systemic lupus erythematosus and cognitive dysfunction: the MRL-lpr mouse strain as a model.
 

Author(s): Hélène Jeltsch-David, Sylviane Muller

Journal: Autoimmun Rev. 2014 Sep;13(9):963-73.

 

Mouse models of autoimmunity, such as (NZB×NZW)F1, MRL/MpJ-Fas(lpr) (MRL-lpr) and BXSB mice, spontaneously develop systemic lupus erythematosus (SLE)-like syndromes with heterogeneity and complexity that characterize human SLE. Despite their inherent limitations, such models have ...

Last Updated: 20 Sep 2014

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Linking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosus.
 

Author(s): Steve P Crampton, Peter A Morawski, Silvia Bolland

Journal: Dis Model Mech. 2014 Sep;7(9):1033-46.

 

Systemic lupus erythematosus (SLE) represents a challenging autoimmune disease from a clinical perspective because of its varied forms of presentation. Although broad-spectrum steroids remain the standard treatment for SLE, they have many side effects and only provide temporary relief ...

Last Updated: 22 Aug 2014

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A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level.
 

Author(s): Jihyun Yang, Min Young Seo, Ki Tae Kim, Jun Yong Lee, Sun-Chul Kim, Myung-Gyu Kim, Sang-Kyung Jo, Won-Yong Cho, Hyoung-Kyu Kim, Nam Hee Won, Ran-Hui Cha, Eunjung Cho

Journal:

 

Human immunodeficiency virus (HIV) infection is growing medical concern worldwide. There are many types of glomerulonephritis which are associated with HIV infection. We report a case of a 53-year-old Korean man with an HIV infection, who was developed nephritic range proteinuria ...

Last Updated: 14 Aug 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Cutaneous Lupus Erythematosus and Elidel
 

Status: Recruiting

Condition Summary: Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Discoid

 

Last Updated: 5 Apr 2007

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Duke Lupus Registry
 

Status: Recruiting

Condition Summary: Systemic Lupus Erythematosus; Cutaneous Lupus

 

Last Updated: 2 Feb 2015

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Lupus Flares and Histological Renal Activity at the End of the Treatment (LuFla)
 

Status: Recruiting

Condition Summary: Lupus Nephritis

 

Last Updated: 9 Dec 2014

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