Lung Cancer

Common Name(s)

Lung Cancer, Cancer, Lung

Lung cancer is a type of cancer that begins in the lung, often in the branching tube-like airways called the bronchi. The major types are small cell lung cancer and non-small cell lung cancer. Within non-small cell lung cancer, there are sub-types, including large-cell carcinoma, squamous cell carcinoma, and adenocarcinoma. Lung cancer occurs when cells in the lung develop mutations that cause the cells to divide rapidly and resist death. Tumors may result.

Signs of lung cancer include a frequent raspy cough, hacking, wheeziness, hoarseness, chest pain, shortness of breath, bloody mucus, difficulty swallowing, recurring lung infections, neck and face swelling, body pain, headaches, fever, weakness, weight loss, and loss of appetite.

Most lung cancers are caused by smoking. Other risk factors include inhaling second-hand smoke; asbestos, radon, and uranium dust exposure; a personal history of lung disease or infection; and a family history of lung cancer. There is some evidence that a diet high in fat and cholesterol may increase the risk of developing lung cancer.

Several tests are used to diagnose lung cancer. In a procedure called a bronchoscopy, a doctor places a narrow tube with a camera down the nose and air passages to view the lung. A biopsy can then collect and analyze lung tissue to check for cancer cells. Blood tests, X-ray imaging, computed tomography (CT) scans, PET scans, and magnetic resonance imaging (MRI) can also be used in diagnosis. Fluid may be removed from the lung with a needle and tested for cancer cells in a procedure called thoracentesis.

Treatment for lung cancer often involves surgical removal of parts of the lung. Chemotherapy and/or radiation therapy may also be used. Cancer pain medication can help alleviate symptoms. If you have been diagnosed with lung cancer, talk to your doctor about the most current treatment options. Support groups are available for more resources and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lung Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Free to Breathe

Free to Breathe is a partnership of lung cancer survivors, advocates, researchers, healthcare professionals and industry leaders united in the belief that every person with lung cancer deserves a cure. Free to Breathe is dedicated to doubling lung cancer survival by 2022.

Last Updated: 16 Oct 2014

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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Lung Cancer Alliance

Lung Cancer Alliance is committed to ending injustice and saving lives through an alliance of advocacy, education and support.

Last Updated: 20 Feb 2013

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Lung Cancer Foundation of America

LCFA’s mission is the dramatic improvement in survivorship of lung cancer patients through the funding of transformative science, with the ultimate goal of curing the disease. To accomplish this, LCFA will work to raise both the funds and the national profile of lung cancer in order to substantially increase support of innovative and groundbreaking research efforts.

Last Updated: 28 Aug 2014

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Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

Last Updated: 6 Nov 2012

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The bonnie j addario lung cancer foundation

Eradicating Lung Cancer with our patients, survivors, and their families through research, early detection, awareness, education, prevention, and treatment.

Last Updated: 15 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lung Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Free to Breathe

Free to Breathe is a partnership of lung cancer survivors, advocates, researchers, healthcare professionals and industry leaders united in the belief that every person with lung cancer deserves a cure. Free to Breathe is dedicated to doubling lung cancer survival by 2022.

http://www.freetobreathe.org

Last Updated: 16 Oct 2014

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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Lung Cancer Alliance

Lung Cancer Alliance is committed to ending injustice and saving lives through an alliance of advocacy, education and support.

http://www.lungcanceralliance.org

Last Updated: 20 Feb 2013

View Details
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Lung Cancer Foundation of America

LCFA’s mission is the dramatic improvement in survivorship of lung cancer patients through the funding of transformative science, with the ultimate goal of curing the disease. To accomplish this, LCFA will work to raise both the funds and the national profile of lung cancer in order to substantially increase support of innovative and groundbreaking research efforts.

http://www.LCFAmerica.org

Last Updated: 28 Aug 2014

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Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

http://stupidcancer.org

Last Updated: 6 Nov 2012

View Details
Logo
The bonnie j addario lung cancer foundation

Eradicating Lung Cancer with our patients, survivors, and their families through research, early detection, awareness, education, prevention, and treatment.

http://www.lungcancerfoundation.org

Last Updated: 15 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lung Cancer" returned 17461 free, full-text research articles on human participants. First 3 results:

Development and Validation of Risk Models to Select Ever-Smokers for CT Lung Cancer Screening.
 

Author(s): Hormuzd A Katki, Stephanie A Kovalchik, Christine D Berg, Li C Cheung, Anil K Chaturvedi

Journal: JAMA. 2016 Jun;315(21):2300-11.

 

The US Preventive Services Task Force (USPSTF) recommends computed tomography (CT) lung cancer screening for ever-smokers aged 55 to 80 years who have smoked at least 30 pack-years with no more than 15 years since quitting. However, selecting ever-smokers for screening using individualized ...

Last Updated: 9 Jun 2016

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Advanced Lab Testing in Lung Cancer.
 

Author(s): Nirali M Patel, Jared Weiss

Journal: Oncology (Williston Park, N.Y.). 2016 Apr;30(4):348, 352.

 

Last Updated: 18 Apr 2016

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Research Advances in Molecular Mechanisms of the Invasion and Metastasis of Lung Cancer.
 

Author(s): Xian-zhong Liu, Li-ting Zhang, Wei-quan Tong, Shuai Wang, Zhi-bo Xu, Fang Chen

Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2016 Feb;38(1):108-12.

 

The basic way of invasion and metastasis of lung cancer is that the tumor cells shed in the extracellular matrix, invade the basement membrane and the surrounding tissue, infiltrate into blood flow, and then survive and transport via the blood flow. After having been extravasated, ...

Last Updated: 21 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lung Cancer" returned 1884 free, full-text review articles on human participants. First 3 results:

Ground-Glass Opacity Lung Nodules in the Era of Lung Cancer CT Screening: Radiology, Pathology, and Clinical Management.
 

Author(s): Jesper Holst Pedersen, Zaigham Saghir, Mathilde Marie Winkler Wille, Laura Hohwü Thomsen, Birgit Guldhammer Skov, Haseem Ashraf

Journal: Oncology (Williston Park, N.Y.). 2016 Mar;30(3):266-74.

 

The advent of computed tomography screening for lung cancer will increase the incidence of ground-glass opacity (GGO) nodules detected and referred for diagnostic evaluation and management. GGO nodules remain a diagnostic challenge; therefore, a more systematic approach is necessary ...

Last Updated: 17 Mar 2016

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Pulmonary Toxicities of Gefitinib in Patients With Advanced Non-Small-Cell Lung Cancer: A Meta-Analysis of Randomized Controlled Trials.
 

Author(s): Dongsheng Hong, Guobing Zhang, Xingguo Zhang, Xingguang Lian

Journal: Medicine (Baltimore). 2016 Mar;95(9):e3008.

 

Gefitinib is a selective tyrosine kinase inhibitor of the epidermal growth factor receptor (EGFR) used to treat adults with EGFR mutation-positive non-small-cell lung cancer (NSCLC). Clinical benefits of gefitinib administration in NSCLC patients have been observed in clinical practice, ...

Last Updated: 6 Mar 2016

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Nicotine-induced resistance of non-small cell lung cancer to treatment--possible mechanisms.
 

Author(s): Rafał Czyżykowski, Joanna Połowinczak-Przybyłek, Piotr Potemski

Journal:

 

Cigarette smoking is the leading risk factor of lung cancer. Data from several clinical studies suggest that continuation of smoking during therapy of tobacco-related cancers is associated with lower response rates to chemotherapy and/or radiotherapy, and even with decreased survival. ...

Last Updated: 5 Mar 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of Ponatinib in Patients With Lung Cancer Preselected Using Different Candidate Predictive Biomarkers
 

Status: Recruiting

Condition Summary: Adenocarcinoma of the Lung; Extensive Stage Small Cell Lung Cancer; Limited Stage Small Cell Lung Cancer; Recurrent Non-small Cell Lung Cancer; Recurrent Small Cell Lung Cancer; Stage IIIA Non-small Cell Lung Cancer; Stage IIIB Non-small Cell Lung Cancer; Stage IV Non-small Cell Lung Cancer

 

Last Updated: 7 Jun 2016

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Circulating Tumor DNA in Patients at High Risk for Lung Cancer
 

Status: Recruiting

Condition Summary: Cancer of the Lung; Lung Cancer; Lung Neoplasms; Adenocarcinoma of the Lung; Non Small Cell Carcinoma of the Lung; Small Cell Carcinoma of the Lung

 

Last Updated: 14 Jul 2016

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Modulation of Autophagy in Patients With Advanced/Recurrent Non-small Cell Lung Cancer - Phase II
 

Status: Recruiting

Condition Summary: Non-small Cell Lung Cancer; Advanced Non-small Cell Lung Cancer; Recurrent Non-small Cell Lung Cancer

 

Last Updated: 8 Jul 2016

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