Lung Cancer

Common Name(s)

Lung Cancer, Cancer, Lung

Lung cancer is a type of cancer that begins in the lung, often in the branching tube-like airways called the bronchi. The major types are small cell lung cancer and non-small cell lung cancer. Within non-small cell lung cancer, there are sub-types, including large-cell carcinoma, squamous cell carcinoma, and adenocarcinoma. Lung cancer occurs when cells in the lung develop mutations that cause the cells to divide rapidly and resist death. Tumors may result.

Signs of lung cancer include a frequent raspy cough, hacking, wheeziness, hoarseness, chest pain, shortness of breath, bloody mucus, difficulty swallowing, recurring lung infections, neck and face swelling, body pain, headaches, fever, weakness, weight loss, and loss of appetite.

Most lung cancers are caused by smoking. Other risk factors include inhaling second-hand smoke; asbestos, radon, and uranium dust exposure; a personal history of lung disease or infection; and a family history of lung cancer. There is some evidence that a diet high in fat and cholesterol may increase the risk of developing lung cancer.

Several tests are used to diagnose lung cancer. In a procedure called a bronchoscopy, a doctor places a narrow tube with a camera down the nose and air passages to view the lung. A biopsy can then collect and analyze lung tissue to check for cancer cells. Blood tests, X-ray imaging, computed tomography (CT) scans, PET scans, and magnetic resonance imaging (MRI) can also be used in diagnosis. Fluid may be removed from the lung with a needle and tested for cancer cells in a procedure called thoracentesis.

Treatment for lung cancer often involves surgical removal of parts of the lung. Chemotherapy and/or radiation therapy may also be used. Cancer pain medication can help alleviate symptoms. If you have been diagnosed with lung cancer, talk to your doctor about the most current treatment options. Support groups are available for more resources and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lung Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Free to Breathe

Free to Breathe is a partnership of lung cancer survivors, advocates, researchers, healthcare professionals and industry leaders united in the belief that every person with lung cancer deserves a cure. Free to Breathe is dedicated to doubling lung cancer survival by 2022.

Last Updated: 16 Oct 2014

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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Lung Cancer Alliance

Lung Cancer Alliance is committed to ending injustice and saving lives through an alliance of advocacy, education and support.

Last Updated: 20 Feb 2013

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Lung Cancer Foundation of America

LCFA’s mission is the dramatic improvement in survivorship of lung cancer patients through the funding of transformative science, with the ultimate goal of curing the disease. To accomplish this, LCFA will work to raise both the funds and the national profile of lung cancer in order to substantially increase support of innovative and groundbreaking research efforts.

Last Updated: 28 Aug 2014

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Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

Last Updated: 6 Nov 2012

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The bonnie j addario lung cancer foundation

Eradicating Lung Cancer with our patients, survivors, and their families through research, early detection, awareness, education, prevention, and treatment.

Last Updated: 15 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lung Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Free to Breathe

Free to Breathe is a partnership of lung cancer survivors, advocates, researchers, healthcare professionals and industry leaders united in the belief that every person with lung cancer deserves a cure. Free to Breathe is dedicated to doubling lung cancer survival by 2022.

http://www.freetobreathe.org

Last Updated: 16 Oct 2014

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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Lung Cancer Alliance

Lung Cancer Alliance is committed to ending injustice and saving lives through an alliance of advocacy, education and support.

http://www.lungcanceralliance.org

Last Updated: 20 Feb 2013

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Lung Cancer Foundation of America

LCFA’s mission is the dramatic improvement in survivorship of lung cancer patients through the funding of transformative science, with the ultimate goal of curing the disease. To accomplish this, LCFA will work to raise both the funds and the national profile of lung cancer in order to substantially increase support of innovative and groundbreaking research efforts.

http://www.LCFAmerica.org

Last Updated: 28 Aug 2014

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Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

http://stupidcancer.org

Last Updated: 6 Nov 2012

View Details
Logo
The bonnie j addario lung cancer foundation

Eradicating Lung Cancer with our patients, survivors, and their families through research, early detection, awareness, education, prevention, and treatment.

http://www.lungcancerfoundation.org

Last Updated: 15 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lung Cancer" returned 20113 free, full-text research articles on human participants. First 3 results:

Expressions of KAI1 and E-cadherin in nonsmall cell lung cancer and their correlation with vasculogenic mimicry.
 

Author(s): Hongfei Ci, Zhouyi Xu, Jing Xu, Yichao Wang, Shiwu Wu

Journal: Medicine (Baltimore). 2018 Oct;97(40):e12293.

 

Metastasis and recurrence are the most common reasons for treatment failure of nonsmall cell lung cancer (NSCLC). Vasculogenic mimicry (VM, new blood supply formation in malignant tumors), E-Cadherin (a calcium-dependent transmembrane glycoprotein that mediates intercellular adhesion), ...

Last Updated: 31 Dec 1969

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Alveolar architectures preserved in cancer tissues may be potential pitfalls for diagnosis and histological subtyping of lung cancer: Three case reports.
 

Author(s): Xiaoxi Fan, Xiupeng Zhang, Enhua Wang, Chuifeng Fan

Journal: Medicine (Baltimore). 2018 Sep;97(39):e12613.

 

Lung cancer is a leading cause of cancer-related deaths globally. Appropriate histopathological diagnosis and subtyping form the basis and are critical for clinical therapies.

Last Updated: 31 Dec 1969

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Problems to affect long-term survival for breast cancer patients: An observational study of subsequent lung/bronchus malignancies.
 

Author(s): Jieqiong Liu, Zheyu Hu, Yuhua Feng, Shan Zeng, Meizuo Zhong

Journal: Medicine (Baltimore). 2018 Sep;97(39):e12603.

 

The overall survival of breast cancer (BC) patients increased significantly for decades; however, their long-term survival was seriously impaired by subsequent malignancies. This study aimed to investigate the risk factors of subsequent lung / bronchus primary malignancies among BC ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lung Cancer" returned 2358 free, full-text review articles on human participants. First 3 results:

Higher pretreatment lactate dehydrogenase concentration predicts worse overall survival in patients with lung cancer.
 

Author(s): Taibing Deng, Jing Zhang, Yu Meng, Yongzhao Zhou, Weimin Li

Journal: Medicine (Baltimore). 2018 Sep;97(38):e12524.

 

The aim of this study was to systematically evaluate the prognostic role of pretreatment lactate dehydrogenase (LDH) concentration for survival in patients with lung cancer through performing a meta-analysis.

Last Updated: 31 Dec 1969

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Associations of the risk of lung cancer with serum 25-hydroxyvitamin D level and dietary vitamin D intake: A dose-response PRISMA meta-analysis.
 

Author(s): Hu Wei, Hu Jing, Qian Wei, Guo Wei, Zhou Heng

Journal: Medicine (Baltimore). 2018 Sep;97(37):e12282.

 

The associations of the risk of lung cancer with the vitamin D intake and serum level are controversial. We performed a comprehensive dose-response meta-analysis to evaluate the precise relationships between the above mentioned parameters.We performed a web search of the PubMed, Medline, ...

Last Updated: 31 Dec 1969

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[Study Progression on Non-small Cell Lung Cancer with EGFR Mutation 
Treated by Immune Checkpoint Inhibitors].
 

Author(s): Rilan Bai, Naifei Chen, Jiuwei Cui

Journal: Zhongguo Fei Ai Za Zhi. 2018 Aug;21(8):641-648.

 

In recent years, epidermal growth factor receptor tyrosine kinase inhibitors have been recommended by many guidelines as first-line drugs for advanced non-small cell lung cancer (NSCLC) with EGFR gene mutations and no resistance. However, with the prolongation of medication time, ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 23 May 2018

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PET/CT Based Radiomics for Lung Cancer (PERL)
 

Status: Recruiting

Condition Summary: Lung Cancer

 

Last Updated: 3 May 2018

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Hybrid APC Therapy in Early Central Lung Cancer
 

Status: Not yet recruiting

Condition Summary: Lung Cancer

 

Last Updated: 12 Sep 2018

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