Lung Cancer

Common Name(s)

Lung Cancer, Cancer, Lung

Lung cancer is a type of cancer that begins in the lung, often in the branching tube-like airways called the bronchi. The major types are small cell lung cancer and non-small cell lung cancer. Within non-small cell lung cancer, there are sub-types, including large-cell carcinoma, squamous cell carcinoma, and adenocarcinoma. Lung cancer occurs when cells in the lung develop mutations that cause the cells to divide rapidly and resist death. Tumors may result.

Signs of lung cancer include a frequent raspy cough, hacking, wheeziness, hoarseness, chest pain, shortness of breath, bloody mucus, difficulty swallowing, recurring lung infections, neck and face swelling, body pain, headaches, fever, weakness, weight loss, and loss of appetite.

Most lung cancers are caused by smoking. Other risk factors include inhaling second-hand smoke; asbestos, radon, and uranium dust exposure; a personal history of lung disease or infection; and a family history of lung cancer. There is some evidence that a diet high in fat and cholesterol may increase the risk of developing lung cancer.

Several tests are used to diagnose lung cancer. In a procedure called a bronchoscopy, a doctor places a narrow tube with a camera down the nose and air passages to view the lung. A biopsy can then collect and analyze lung tissue to check for cancer cells. Blood tests, X-ray imaging, computed tomography (CT) scans, PET scans, and magnetic resonance imaging (MRI) can also be used in diagnosis. Fluid may be removed from the lung with a needle and tested for cancer cells in a procedure called thoracentesis.

Treatment for lung cancer often involves surgical removal of parts of the lung. Chemotherapy and/or radiation therapy may also be used. Cancer pain medication can help alleviate symptoms. If you have been diagnosed with lung cancer, talk to your doctor about the most current treatment options. Support groups are available for more resources and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lung Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Free to Breathe

Free to Breathe is a partnership of lung cancer survivors, advocates, researchers, healthcare professionals and industry leaders united in the belief that every person with lung cancer deserves a cure. Free to Breathe is dedicated to doubling lung cancer survival by 2022.

Last Updated: 16 Oct 2014

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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Lung Cancer Alliance

Lung Cancer Alliance is committed to ending injustice and saving lives through an alliance of advocacy, education and support.

Last Updated: 20 Feb 2013

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Lung Cancer Foundation of America

LCFA’s mission is the dramatic improvement in survivorship of lung cancer patients through the funding of transformative science, with the ultimate goal of curing the disease. To accomplish this, LCFA will work to raise both the funds and the national profile of lung cancer in order to substantially increase support of innovative and groundbreaking research efforts.

Last Updated: 28 Aug 2014

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Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

Last Updated: 6 Nov 2012

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The bonnie j addario lung cancer foundation

Eradicating Lung Cancer with our patients, survivors, and their families through research, early detection, awareness, education, prevention, and treatment.

Last Updated: 15 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lung Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Free to Breathe

Free to Breathe is a partnership of lung cancer survivors, advocates, researchers, healthcare professionals and industry leaders united in the belief that every person with lung cancer deserves a cure. Free to Breathe is dedicated to doubling lung cancer survival by 2022.

http://www.freetobreathe.org

Last Updated: 16 Oct 2014

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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Lung Cancer Alliance

Lung Cancer Alliance is committed to ending injustice and saving lives through an alliance of advocacy, education and support.

http://www.lungcanceralliance.org

Last Updated: 20 Feb 2013

View Details
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Lung Cancer Foundation of America

LCFA’s mission is the dramatic improvement in survivorship of lung cancer patients through the funding of transformative science, with the ultimate goal of curing the disease. To accomplish this, LCFA will work to raise both the funds and the national profile of lung cancer in order to substantially increase support of innovative and groundbreaking research efforts.

http://www.LCFAmerica.org

Last Updated: 28 Aug 2014

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Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

http://stupidcancer.org

Last Updated: 6 Nov 2012

View Details
Logo
The bonnie j addario lung cancer foundation

Eradicating Lung Cancer with our patients, survivors, and their families through research, early detection, awareness, education, prevention, and treatment.

http://www.lungcancerfoundation.org

Last Updated: 15 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lung Cancer" returned 16631 free, full-text research articles on human participants. First 3 results:

Effect of compound Kushen injection on T-cell subgroups and natural killer cells in patients with locally advanced non-small-cell lung cancer treated with concomitant radiochemotherapy.
 

Author(s): Zhongquan Zhao, Hehe Liao, Ying Ju

Journal: J Tradit Chin Med. 2016 Feb;36(1):14-8.

 

To observe effect of compound Kushen injection on T-cell subgroups and NK cells in patients with locally advanced non-small-cell lung cancer (NSCLC) treated with concomitant radiochemotherapy.

Last Updated: 7 Mar 2016

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Nivolumab in Nonsquamous Non-Small-Cell Lung Cancer.
 

Author(s): Hossein Borghaei, Julie Brahmer

Journal: N. Engl. J. Med.. 2016 Feb;374(5):493-4.

 

Last Updated: 4 Feb 2016

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Race and Gender Disparities in Lung Cancer Incidence Rates, 2001-2010.
 

Author(s): Dana S Mowls, Janis Campbell, Laura A Beebe

Journal: J Okla State Med Assoc. 2015 Nov;108(11):482-7.

 

Despite progress to reduce the burden of tobacco, disparities in tobacco-related morbidity and mortality remain. This research examines trends in lung cancer incidence rates by race and by gender within race during 2001-2010 in Oklahoma.

Last Updated: 27 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lung Cancer" returned 1807 free, full-text review articles on human participants. First 3 results:

[Advances in Diagnosis and Treatment of Multiple Primary Lung Cancer].
 

Author(s): Wenxin Luo, Ping Zhou, Weimin Li

Journal: Zhongguo Fei Ai Za Zhi. 2015 Oct;18(10):640-3.

 

Recently, the incidence and detection rates of multiple primary lung cancer (MPLC) are increasing. The diagnosis of MPLC depends mainly on the Martini-Melamed criterion and ACCP criterion at present, taking all features (histological, genetic, radiologic and clinical) into account. ...

Last Updated: 20 Oct 2015

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[Advances in Lung Stem Cells and Lung Cancer Stem Cells].
 

Author(s): Huijing Yin, Jiong Deng

Journal: Zhongguo Fei Ai Za Zhi. 2015 Oct;18(10):633-9.

 

Cancer stem cells (CSCs) are emerging as a hot topic for cancer research. Lung CSCs share many characteristics with normal lung stem cells (SCs), including self-renewal and multi-potency for differentiation. Many molecular markers expressed in various types of CSCs were also found ...

Last Updated: 20 Oct 2015

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[Diagnosis and Treatment of Leptomeningeal Metastasis in Non-small Cell Lung Cancer].
 

Author(s): Yan Xu, Longyun Li, Mengzhao Wang

Journal: Zhongguo Fei Ai Za Zhi. 2015 Oct;18(10):626-32.

 

Leptomeningeal metastasis (LM) is one of the disastrous events in managing advanced non-small cell lung cancer (NSCLC) due to severe clinical symptoms and a grave prognosis. Although intrathecal (IT) chemotherapy show some effects for LM in advanced NSCLC, the prognosis is still poor ...

Last Updated: 20 Oct 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of Ponatinib in Patients With Lung Cancer Preselected Using Different Candidate Predictive Biomarkers
 

Status: Recruiting

Condition Summary: Adenocarcinoma of the Lung; Extensive Stage Small Cell Lung Cancer; Limited Stage Small Cell Lung Cancer; Recurrent Non-small Cell Lung Cancer; Recurrent Small Cell Lung Cancer; Stage IIIA Non-small Cell Lung Cancer; Stage IIIB Non-small Cell Lung Cancer; Stage IV Non-small Cell Lung Cancer

 

Last Updated: 3 Dec 2015

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Circulating Tumor DNA in Patients at High Risk for Lung Cancer
 

Status: Recruiting

Condition Summary: Cancer of the Lung; Lung Cancer; Lung Neoplasms; Adenocarcinoma of the Lung; Non Small Cell Carcinoma of the Lung; Small Cell Carcinoma of the Lung

 

Last Updated: 16 Mar 2016

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Modulation of Autophagy in Patients With Advanced/Recurrent Non-small Cell Lung Cancer - Phase II
 

Status: Recruiting

Condition Summary: Non-small Cell Lung Cancer; Advanced Non-small Cell Lung Cancer; Recurrent Non-small Cell Lung Cancer

 

Last Updated: 10 Jun 2015

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