Oligohydramnios

Common Name(s)

Oligohydramnios, Low amniotic fluid

Low amniotic fluid, or oligohydramnios, is a condition experienced by pregnant women with variable causes and treatments. When a baby is developing, it is surrounded by amniotic fluid. This fluid helps create a safe and stable environment for the baby by helping maintain temperature, providing a medium for the baby to move in, preventing umbilical cord compression, and serving as a cushion between the baby and the mother. Normally, fluid level gradually increases until 34–36 weeks of pregnancy, reaching about a quart of fluid, and then gradually decreases until birth. A low level of fluid, especially in the earlier stages of pregnancy, can indicate problems with the developing baby or its environment. Some of the most common causes of low amniotic fluid are a tear in the amniotic membrane, the separation of the placenta from the uterine wall, a birth defect, twins, and certain medical conditions in the mother, such as high blood pressure or diabetes. Signs of low fluid include leaking fluid from the vagina, measuring small for a certain stage of pregnancy, and a decrease in movement from the baby. An ultrasound is used to confirm amniotic fluid level. In many cases low fluid level is monitored but left unaltered, for example, a tear in the amniotic sac that is likely to heal. In late stage pregnancies with very low levels of fluid, labor is often induced. During this type of delivery, warm salt water is often pumped into the amniotic sac through the cervix to keep fluid levels stable and prevent umblical cord compression. Alternatively, a C-section may be performed.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Oligohydramnios" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Oligohydramnios" returned 32 free, full-text research articles on human participants. First 3 results:

Oligohydramnios in women with preterm prelabor rupture of membranes and adverse pregnancy and neonatal outcomes.
 

Author(s): Marian Kacerovsky, Ivana Musilova, Ctirad Andrys, Marcela Drahosova, Helena Hornychova, Adam Rezac, Milan Kostal, Bo Jacobsson

Journal:

 

To determine the association between the presence of oligohydramnios, determined as an amniotic fluid index ≤ 5 cm and the intra-amniotic inflammatory response, fetal inflammatory response and neonatal outcomes in actively managed preterm prelabor rupture of membranes (PPROM).

Last Updated: 30 Aug 2014

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Oligohydramnios in a pregnant Pakistani woman with Plasmodium vivax malaria.
 

Author(s): Nicolò Binello, Enrico Brunetti, Federico Cattaneo, Raffaella Lissandrin, Antonello Malfitano

Journal:

 

In the Western world, the diagnosis and management of Plasmodium vivax malaria in pregnant women can be challenging, and the pathogenesis of adverse outcomes for both the mother and the foetus is still poorly known. The authors describe the case of a 29-year-old Pakistani woman at ...

Last Updated: 30 Apr 2014

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Female pseudohermaphroditism in a prenatally diagnosed cloacal malformation with hydronephrosis, dilated bladder, hydrometrocolpos, and oligohydramnios.
 

Author(s): Chih-Ping Chen, Chen-Yu Chen, Jun-Wei Su, Wayseen Wang

Journal: Taiwan J Obstet Gynecol. 2013 Dec;52(4):571-4.

 

To present female pseudohermaphroditism in a prenatally diagnosed cloacal malformation.

Last Updated: 13 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Oligohydramnios" returned 4 free, full-text review articles on human participants. First 3 results:

An Update on Maternal Hydration Strategies for Amniotic Fluid Improvement in Isolated Oligohydramnios and Normohydramnios: Evidence from a Systematic Review of Literature and Meta-Analysis.
 

Author(s): Salvatore Gizzo, Marco Noventa, Amerigo Vitagliano, Andrea Dall'Asta, Donato D'Antona, Clive J Aldrich, Michela Quaranta, Tiziana Frusca, Tito Silvio Patrelli

Journal:

 

Several trials aimed at evaluating the efficacy of maternal hydration (MH) in increasing amniotic-fluid-volume (AFV) in pregnancies with isolated oligohydramnios or normohydramnos have been conducted. Unfortunately, no evidences support this intervention in routine-clinical-practice. ...

Last Updated: 15 Dec 2015

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Important clinical information from successful treatment of a case with isolated severe oligohydramnios and deficient fetal growth late in the second trimester.
 

Author(s): Fu-Nan Cho, San-Nung Chen, Ju-Yueh Li, Yu-Hsiang Chang, James R Carey, Wen-Shiung Liou

Journal: Taiwan J Obstet Gynecol. 2015 Aug;54(4):459-60.

 

Last Updated: 19 Sep 2015

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Pulmonary effects of prolonged oligohydramnios following mid-trimester rupture of the membranes--antenatal and postnatal management.
 

Author(s): Olivia Williams, Graham Hutchings, Corinne Hubinont, Christian Debauche, Anne Greenough

Journal: Neonatology. 2012 ;101(2):83-90.

 

Mid-trimester, preterm prelabour rupture of the membranes (PPROM) with prolonged oligohydramnios remains a challenge for both obstetricians and neonatologists. Although survival rates have improved, morbidity remains common particularly due to pulmonary insufficiency and pulmonary ...

Last Updated: 7 Feb 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Fetal Renal Artery Doppler Indices in Borderline Isolated Oligohydramnios
 

Status: Recruiting

Condition Summary: Oligohydramnios

 

Last Updated: 14 Sep 2016

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Sildenafil Citrate Therapy for Oligohydramnios
 

Status: Recruiting

Condition Summary: Pregnancy Complication

 

Last Updated: 2 Feb 2016

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PPROM Registry (Preterm Premature Rupture of Membranes)
 

Status: Recruiting

Condition Summary: Fetal Membranes, Premature Rupture; Preterm Premature Rupture of the Membranes; Oligohydramnios; Premature Birth

 

Last Updated: 15 Dec 2016

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