Long QT syndrome 2

Common Name(s)

Long QT syndrome 2

Congenital long QT syndrome is electrocardiographically characterized by a prolonged QT interval and polymorphic ventricular arrhythmias (torsade de pointes). These cardiac arrhythmias may result in recurrent syncope, seizure, or sudden death ({7:Jongbloed et al., 1999}). For a discussion of genetic heterogeneity of long QT syndrome, see LQT1 ({192500}).
 

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Condition Specific Organizations

Following organizations serve the condition "Long QT syndrome 2" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Long QT syndrome 2" returned 37 free, full-text research articles on human participants. First 3 results:

Multigenerational Inheritance of Long QT Syndrome Type 2 in a Japanese Family.
 

Author(s): Mari Ichikawa, Seiko Ohno, Yusuke Fujii, Junichi Ozawa, Keiko Sonoda, Megumi Fukuyama, Koichi Kato, Hiromi Kimura, Hideki Itoh, Hideki Hayashi, Minoru Horie

Journal: Intern. Med.. 2016 ;55(3):259-62.

 

Congenital long QT syndrome (LQTS) is an important cause of sudden cardiac death in young people without any other structural disease. Mutations in the genes encoding the cardiac ion channels or associated proteins have been shown to result in ion channel dysfunction and thereby causing ...

Last Updated: 2 Feb 2016

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Toward Personalized Medicine: Using Cardiomyocytes Differentiated From Urine-Derived Pluripotent Stem Cells to Recapitulate Electrophysiological Characteristics of Type 2 Long QT Syndrome.
 

Author(s): Mariam Jouni, Karim Si-Tayeb, Zeineb Es-Salah-Lamoureux, Xenia Latypova, Benoite Champon, Amandine Caillaud, Anais Rungoat, Flavien Charpentier, Gildas Loussouarn, Isabelle Baró, Kazem Zibara, Patricia Lemarchand, Nathalie Gaborit

Journal:

 

Human genetically inherited cardiac diseases have been studied mainly in heterologous systems or animal models, independent of patients' genetic backgrounds. Because sources of human cardiomyocytes (CMs) are extremely limited, the use of urine samples to generate induced pluripotent ...

Last Updated: 2 Sep 2015

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Analysis for Genetic Modifiers of Disease Severity in Patients With Long-QT Syndrome Type 2.
 

Author(s): Iris C R M Kolder, Michael W T Tanck, Pieter G Postema, Julien Barc, Moritz F Sinner, Sven Zumhagen, Anja Husemann, Birgit Stallmeyer, Tamara T Koopmann, Nynke Hofman, Arne Pfeufer, Peter Lichtner, Thomas Meitinger, Britt M Beckmann, Robert J Myerburg, Nanette H Bishopric, Dan M Roden, Stefan Kääb, Arthur A M Wilde, Jean-Jacques Schott, Eric Schulze-Bahr, Connie R Bezzina

Journal: Circ Cardiovasc Genet. 2015 Jun;8(3):447-56.

 

Considerable interest exists in the identification of genetic modifiers of disease severity in the long-QT syndrome (LQTS) as their identification may contribute to refinement of risk stratification.

Last Updated: 17 Jun 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Long QT syndrome 2" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Comparison Between Epinephrine and Exercise Test in QT Long Syndrome Patients
 

Status: Recruiting

Condition Summary: Long QT Syndrome Type 1 or 2

 

Last Updated: 12 Apr 2016

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Last Updated: 17 Apr 2014

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