Long QT Syndrome

Common Name(s)

Long QT Syndrome

Long QT syndrome is a disorder of the heart’s electrical activity that can cause sudden, uncontrollable, and irregular heartbeats (arrhythmia), which may lead to sudden death. Long QT syndrome can be detected by electrocardiogram (EKG). It can be caused by a variety of different gene mutations (changes). It can also be acquired (noninherited) and may be brought on by certain medicines and other medical conditions.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Long QT Syndrome" for support, advocacy or research.

Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

Last Updated: 4 May 2015

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SADS (Sudden Arrhythmia Death Syndromes) Foundation

Our mission is to save the lives of young people who are genetically predisposed to sudden death due to cardiac arrhythmia and to provide education and support to families and the medical community.

Last Updated: 23 Apr 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Long QT Syndrome" for support, advocacy or research.

Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

http://www.kidswithheart.org

Last Updated: 4 May 2015

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SADS (Sudden Arrhythmia Death Syndromes) Foundation

Our mission is to save the lives of young people who are genetically predisposed to sudden death due to cardiac arrhythmia and to provide education and support to families and the medical community.

http://www.StopSADS.org

Last Updated: 23 Apr 2015

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General Support Organizations

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General Resources

Drugs to Avoid List

Listing of drugs to avoid if you have Long QT Syndrome

Updated 29 Apr 2014

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SADS Foundation Website

Information on living with SADS, diagnosis, treatment, prevention, and advocacy/education.

Updated 29 Apr 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Long QT Syndrome" returned 613 free, full-text research articles on human participants. First 3 results:

Common founder effects of hereditary hemochromatosis, Wilson´s disease, the long QT syndrome and autosomal recessive deafness caused by two novel mutations in the and genes.
 

Author(s): K Sigvard Olsson, Olof Wålinder, Ulf Jansson, Maria Wilbe, Marie-Louise Bondeson, Eva-Lena Stattin, Ruma Raha-Chowdhury, Roger Williams

Journal:

 

Genealogy and molecular genetic studies of a Swedish river valley population resulted in a large pedigree, showing that the hereditary hemochromatosis (HH) C282Y mutation is inherited with other recessive disorders such as Wilson´s disease (WND), a rare recessive disorder of copper ...

Last Updated: 31 Dec 1969

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[Long QT syndrome and polymorphic ventricular tachycardia due to hypopituitarism. Report of one case].
 

Author(s): José Miguel García-Castro, Antonia García-Martín, Emilio Guirao-Arrabal, Pedro Luis Carrillo-Alascio

Journal: Rev Med Chil. 2017 Jul;145(7):941-944.

 

Symptoms of hypopituitarism are usually chronic and nonspecific, but rarely the disease can have acute and life threatening manifestations. We report a 53 years old female with a pituitary adenoma that was admitted to our hospital because of syncope. The electrocardiogram showed sinus ...

Last Updated: 31 Dec 1969

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Effectiveness of beta-blockers depending on the genotype of congenital long-QT syndrome: A meta-analysis.
 

Author(s): Jinhee Ahn, Hyun Jung Kim, Jong-Il Choi, Kwang No Lee, Jaemin Shim, Hyeong Sik Ahn, Young-Hoon Kim

Journal:

 

Beta-blockers are first-line therapy in patients with congenital long-QT syndrome (LQTS).

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Long QT Syndrome" returned 53 free, full-text review articles on human participants. First 3 results:

Molecular Pathophysiology of Congenital Long QT Syndrome.
 

Author(s): M S Bohnen, G Peng, S H Robey, C Terrenoire, V Iyer, K J Sampson, R S Kass

Journal: Physiol. Rev.. 2017 01;97(1):89-134.

 

Ion channels represent the molecular entities that give rise to the cardiac action potential, the fundamental cellular electrical event in the heart. The concerted function of these channels leads to normal cyclical excitation and resultant contraction of cardiac muscle. Research ...

Last Updated: 31 Dec 1969

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Evaluation and Management of Athletes With Long QT Syndrome.
 

Author(s): Andrew T Gomez, Jordan M Prutkin, Ashwin L Rao

Journal: Sports Health. ;8(6):527-535.

 

The congenital long QT syndrome (LQTS) is an inherited channelopathy known for its electrocardiographic manifestations of QT prolongation and its hallmark arrhythmia, torsades de pointes (TdP). TdP can lead to syncope or sudden death and is often precipitated by triggers such as physical ...

Last Updated: 31 Dec 1969

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A Tale of 2 Diseases: The History of Long-QT Syndrome and Brugada Syndrome.
 

Author(s): Ofer Havakuk, Sami Viskin

Journal: J. Am. Coll. Cardiol.. 2016 Jan;67(1):100-8.

 

The Brugada syndrome (BrS) and long-QT syndrome (LQTS) present as congenital or acquired disorders with diagnostic electrocardiograms (ST-segment elevation and prolonged QT interval, respectively) and increased risk for malignant arrhythmias. Our understanding of the 2 disease forms ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Long QT Syndrome Screening in Newborns
 

Status: Recruiting

Condition Summary: Long QT Syndrome

 

Last Updated: 26 Sep 2016

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Prospective Identification of Long QT Syndrome in Fetal Life
 

Status: Recruiting

Condition Summary: Long QT Syndrome

 

Last Updated: 1 Sep 2017

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The Canadian National Long QT Syndrome Registry
 

Status: Recruiting

Condition Summary: Long QT Syndrome

 

Last Updated: 16 May 2016

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