Liposarcoma

Common Name(s)

Liposarcoma

Liposarcoma is a tumor that arises from fat tissue.  This tumor often occurs in the thigh, behind the knee, or in the abdomen, but it can be found in other parts of the body.  Because a liposarcoma may grow into surrounding tissues or organs, it is considered a malignant tumor.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Liposarcoma" for support, advocacy or research.

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Liposarcoma" for support, advocacy or research.

Logo
Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Liposarcoma" returned 303 free, full-text research articles on human participants. First 3 results:

Synergistic effects of targeted PI3K signaling inhibition and chemotherapy in liposarcoma.
 

Author(s): Shang Guo, Hector Lopez-Marquez, Kenneth C Fan, Edwin Choy, Gregory Cote, David Harmon, G Petur Nielsen, Cao Yang, Changqing Zhang, Henry Mankin, Francis J Hornicek, Darrell R Borger, Zhenfeng Duan

Journal:

 

While liposarcoma is the second most common soft tissue malignant tumor, the molecular pathogenesis in this malignancy is poorly understood. Our goal was therefore to expand the understanding of molecular mechanisms that drive liposarcoma and identify therapeutically-susceptible genetic ...

Last Updated: 3 Apr 2014

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Retroperitoneal liposarcoma with colonic involvement: a case report.
 

Author(s): Yuya Sato, Seiichiro Yamamoto, Shin Fujita

Journal: Jpn. J. Clin. Oncol.. 2014 Apr;44(4):374-8.

 

A 72-year-old male visited a local hospital on presentation of melena. Colonoscopy revealed a protruded lesion in the ascending colon, and computed tomography revealed a 20 cm retroperitoneal tumor. Biopsy failed to provide a definitive diagnosis of the colonic lesion. He was diagnosed ...

Last Updated: 2 Apr 2014

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Whole genome analyses of a well-differentiated liposarcoma reveals novel SYT1 and DDR2 rearrangements.
 

Author(s): Jan B Egan, Michael T Barrett, Mia D Champion, Sumit Middha, Elizabeth Lenkiewicz, Lisa Evers, Princy Francis, Jessica Schmidt, Chang-Xin Shi, Scott Van Wier, Sandra Badar, Gregory Ahmann, K Martin Kortuem, Nicole J Boczek, Rafael Fonseca, David W Craig, John D Carpten, Mitesh J Borad, A Keith Stewart

Journal:

 

Liposarcoma is the most common soft tissue sarcoma, but little is known about the genomic basis of this disease. Given the low cell content of this tumor type, we utilized flow cytometry to isolate the diploid normal and aneuploid tumor populations from a well-differentiated liposarcoma ...

Last Updated: 7 Feb 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Liposarcoma" returned 22 free, full-text review articles on human participants. First 3 results:

Paratesticular dedifferentiated liposarcoma with leiomyosarcomatous differentiation: a case report with a review of literature.
 

Author(s): Kazuhito Hatanaka, Takako Yoshioka, Takashi Tasaki, Akihide Tanimoto

Journal:

 

Paratesticular liposarcoma is a rare neoplasm, described in single case studies or components of larger studies, as histologically well-differentiated liposarcoma (WDL) and dedifferentiated liposarcoma (DL). However, leiomyosarcomatous differentiation is an extremely rare occurrence ...

Last Updated: 15 Nov 2013

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Liposarcoma of the spermatic cord mimicking a left inguinal hernia: a case report and literature review.
 

Author(s): Fubiao Li, Runhui Tian, Changjiu Yin, Xiaofan Dai, Hongliang Wang, Ning Xu, Kaimin Guo

Journal:

 

Liposarcoma of the spermatic cord (LSC) is a rare condition characterized by a painless inguinal or scrotal mass. To our knowledge, only about 200 cases have been previously reported in the literature. These tumors are often mistaken for common scrotal swellings, such as hydroceles ...

Last Updated: 4 Mar 2013

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TAR DNA binding protein-43 and fused in sarcoma/translocated in liposarcoma protein in two neurodegenerative diseases.
 

Author(s): Xin-ning Wang, Li-ying Cui

Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2012 Jun;34(3):286-92.

 

TAR DNA binding protein-43(TDP-43) and fused in sarcoma/translocated in liposarcoma protein (FUS/TLS) have been found to be associated with two neurodegenerative diseases - amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Mutations in TDP-43 and FUS/TLS lead ...

Last Updated: 10 Jul 2012

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Dose Reduction of Preoperative Radiotherapy in Myxoid Liposarcomas
 

Status: Recruiting

Condition Summary: Myxoid Liposarcoma of Soft Tissue

 

Last Updated: 10 Apr 2014

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Last Updated: 23 Apr 2013

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Last Updated: 19 Sep 2014

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