Liposarcoma

Common Name(s)

Liposarcoma

Liposarcoma is a tumor that arises from fat tissue.  This tumor often occurs in the thigh, behind the knee, or in the abdomen, but it can be found in other parts of the body.  Because a liposarcoma may grow into surrounding tissues or organs, it is considered a malignant tumor.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Liposarcoma" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Liposarcoma" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

View Details

 

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Liposarcoma" returned 414 free, full-text research articles on human participants. First 3 results:

Multidetector Computed Tomography Features in Differentiating Exophytic Renal Angiomyolipoma from Retroperitoneal Liposarcoma: A Strobe-Compliant Observational Study.
 

Author(s): Qiushi Wang, Yu-Hsiang Juan, Yong Li, Jia-Jun Xie, Hui Liu, Hongfei Huang, Zaiyi Liu, Junhui Zheng, Ujwala S Saboo, Sachin S Saboo, Changhong Liang

Journal: Medicine (Baltimore). 2015 Sep;94(37):e1521.

 

This study aims to evaluate the multidetector computed tomography (CT) imaging features in differentiating exophytic renal angiomyolipoma (AML) from retroperitoneal liposarcoma. We retrospectively enrolled 42 patients with confirmed exophytic renal AML (31 patients) or retroperitoneal ...

Last Updated: 17 Sep 2015

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Increased H3K9me3 drives dedifferentiated phenotype via KLF6 repression in liposarcoma.
 

Author(s): Emily Z Keung, Kadir C Akdemir, Ghadah A Al Sannaa, Jeannine Garnett, Dina Lev, Keila E Torres, Alexander J Lazar, Kunal Rai, Lynda Chin

Journal: J. Clin. Invest.. 2015 Aug;125(8):2965-78.

 

Liposarcoma (LPS) can be divided into 4 different subtypes, of which well-differentiated LPS (WDLPS) and dedifferentiated LPS (DDLPS) are the most common. WDLPS is typically low grade, whereas DDLPS is high grade, aggressive, and carries a worse prognosis. WDLPS and DDLPS frequently ...

Last Updated: 4 Aug 2015

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The hepatocyte growth factor receptor as a potential therapeutic target for dedifferentiated liposarcoma.
 

Author(s): Kate Lynn J Bill, Jeannine Garnett, Xiaoyan Ma, Caitlin D May, Svetlana Bolshakov, Alexander J Lazar, Dina C Lev, Raphael E Pollock

Journal: Lab. Invest.. 2015 Aug;95(8):951-61.

 

Dedifferentiated liposarcomas (DDLPS) are highly resistant to conventional chemo- and radiotherapies, with surgical resection remaining the classic treatment strategy; therefore, there is a pressing need for novel anti-DDLPS-targeted chemotherapeutics. Hepatocyte growth factor receptor ...

Last Updated: 29 Jul 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Liposarcoma" returned 27 free, full-text review articles on human participants. First 3 results:

Liposarcoma of the larynx: report of a case and review of literature.
 

Author(s): Yang Han, Lian-He Yang, Ting-Ting Liu, Jian Wang, Hong Li, Gang Yu, Zheng Wang, Jia-Jia Lv, Huan-Yu Zhao, En-Hua Wang

Journal:

 

Liposarcomas of the larynx are extremely rare tumors, with only 37 cases reported in the English or French literature to date. The first two cases of laryngeal liposarcomas were reported respectively by Kapur and Dockerty in 1968 [1, 2]. Liposarcoma of the larynx is at high risk of ...

Last Updated: 10 Mar 2015

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[Myxoid primitive liposarcoma of the middle mediastinum].
 

Author(s): Rachid Marouf, Ihssan Alloubi

Journal:

 

Last Updated: 24 Feb 2015

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Recurrence of paratesticular liposarcoma: a case report and review of the literature.
 

Author(s): Raimondo Gabriele, Giuseppe Ferrara, Maria Rita Tarallo, Alessio Giordano, Antonietta De Gori, Luciano Izzo, Marco Conte

Journal:

 

Paratesticular liposarcomas are rare tumors that typically affect adult. Diagnosis is very difficult and inadequate surgical excision leads to a high rate of recurrence.We report a case of local recurrence of paratesticular liposarcoma diagnosed six months following surgery.Since ...

Last Updated: 17 Sep 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Dose Reduction of Preoperative Radiotherapy in Myxoid Liposarcomas
 

Status: Recruiting

Condition Summary: Myxoid Liposarcoma of Soft Tissue

 

Last Updated: 8 Oct 2015

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Last Updated: 7 Nov 2015

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A Phase II Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated Liposarcoma
 

Status: Not yet recruiting

Condition Summary: Liposarcoma; Soft Tissue Sarcoma

 

Last Updated: 7 Oct 2015

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