Limbic encephalitis

Common Name(s)

Limbic encephalitis

Limbic encephalitis is a condition marked by the inflammation of the limbic system and other parts of the brain. The cardinal sign of limbic encephalitis is a severe impairment of short-term memory; however, symptoms may also include confusion, psychiatric symptoms, and seizures. The symptoms typically develop over a few weeks or months, but they may evolve over a few days. Delayed diagnosis is common, but improvements are being made to assist in early detection. Early diagnosis may improve the outcome of limbic encephalitis.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Limbic encephalitis" for support, advocacy or research.

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Autoimmune Encephalitis Alliance

The Autoimmune Encephalitis Alliance improves the lives of patients with autoimmune encephalitis by promoting collaboration across clinical and basic research and by creating a community of patients, families and caregivers so that no one faces autoimmune encephalitis alone.

Last Updated: 25 Mar 2013

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Encephalitis Global Inc.

Encephalitis Global (E Global) is a U.S.A. 501(c)(3) public charity formed in 2005 as an alliance connecting encephalitis survivors and caregivers around the world. E Global strives to raise awareness, aiming to promote swift diagnosis, to alleviate unnecessary suffering and to prevent untimely death.

Last Updated: 19 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Limbic encephalitis" for support, advocacy or research.

Logo
Autoimmune Encephalitis Alliance

The Autoimmune Encephalitis Alliance improves the lives of patients with autoimmune encephalitis by promoting collaboration across clinical and basic research and by creating a community of patients, families and caregivers so that no one faces autoimmune encephalitis alone.

http://www.aealliance.org

Last Updated: 25 Mar 2013

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Encephalitis Global Inc.

Encephalitis Global (E Global) is a U.S.A. 501(c)(3) public charity formed in 2005 as an alliance connecting encephalitis survivors and caregivers around the world. E Global strives to raise awareness, aiming to promote swift diagnosis, to alleviate unnecessary suffering and to prevent untimely death.

http://www.encephalitisglobal.org

Last Updated: 19 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Limbic encephalitis" returned 133 free, full-text research articles on human participants. First 3 results:

Paraneoplastic limbic encephalitis with associated hypothalamitis mimicking a hyperdense hypothalamic tumor: a case report.
 

Author(s): Vipula R Bataduwaarachchi, Nirmali Tissera

Journal:

 

Paraneoplastic limbic encephalitis is an uncommon association of common malignancies such as small cell lung carcinoma, testicular teratoma, and breast carcinoma. The nonspecific nature of the clinical presentation, lack of freely available diagnostic markers, and requirement for ...

Last Updated: 19 Jan 2016

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[Faciobrachial dystonic seizures. Semiologic diagnosis in limbic encephalitis].
 

Author(s): Karina A González Otárula, Gabriela Ugarnes, Marcos Fernández Suárez, Carlos D'Giano

Journal: Medicina (B Aires). 2015 ;75(6):407-9.

 

Limbic encephalitis (LE) associated with positive potassium channel complex antibodies often manifests with faciobrachial dystonic seizures (FBDS). We retrospectively analyze two cases, admitted to our video-EEG unit between 2006 and 2014. Both patients were males, aged 66 and 76 ...

Last Updated: 28 Dec 2015

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Autobiographical age awareness disturbance syndrome in autoimmune limbic encephalitis: two case reports.
 

Author(s): Takeshi Kuroda, Akinori Futamura, Azusa Sugimoto, Akira Midorikawa, Motoyasu Honma, Mitsuru Kawamura

Journal:

 

Autobiographical memory is a form of episodic memory characterized by a sense of time and consciousness that enables an individual to subjectively re-experience his or her past. As part of this mental re-enactment, the past is recognized relative to the present. Dysfunction of this ...

Last Updated: 21 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Limbic encephalitis" returned 10 free, full-text review articles on human participants. First 3 results:

Recognizing Autoimmune-Mediated Encephalitis in the Differential Diagnosis of Limbic Disorders.
 

Author(s): A J da Rocha, R H Nunes, A C M Maia, L L F do Amaral

Journal: AJNR Am J Neuroradiol. 2015 Dec;36(12):2196-205.

 

Limbic encephalitis is far more common than previously thought. It is not always associated with cancer, and it is potentially treatable. Autoantibodies against various neuronal cell antigens may arise independently or in association with cancer and cause autoimmune damage to the ...

Last Updated: 16 Dec 2015

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Are onconeural antibodies a clinical phenomenology in paraneoplastic limbic encephalitis?
 

Author(s): Hongliang Zhang, Chunkui Zhou, Limin Wu, Fengming Ni, Jie Zhu, Tao Jin

Journal: Mediators Inflamm.. 2013 ;2013():172986.

 

Paraneoplastic neurological syndromes (PNSs) occur in patients with cancer and can cause clinical symptoms and signs of dysfunction of the nervous system that are not due to a local effect of the tumor or its metastases. Most of these clinical syndromes in adults are associated with ...

Last Updated: 28 Aug 2013

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[Recent concept of limbic encephalitis: progress in anti-NMDA receptor encephalitis].
 

Author(s): Shigeaki Suzuki, Morinobu Seki, Norihiro Suzuki

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2013 ;36(2):86-94.

 

Patients with limbic encephalitis usually present with rapidly progressive short-term memory deficits, psychiatric symptoms, and seizures. The recent concept of limbic encephalitis has been expanded. Especially, various types of autoimmune limbic encephalitis are associated with autoantibodies ...

Last Updated: 30 Apr 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Antibodies Causing Epilepsy Syndromes: The ACES Study.
 

Status: Recruiting

Condition Summary: Auto-immune Encephalitis; Epilepsy

 

Last Updated: 13 Jun 2016

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