Anaplastic Large Cell Lymphoma

Common Name(s)

Anaplastic Large Cell Lymphoma

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anaplastic Large Cell Lymphoma" for support, advocacy or research.

National Bone Marrow Transplant Link

The mission of the National Bone Marrow Transplant Link is to help patients, caregivers, and families cope with the social and emotional challenges of bone marrow/stem cell transplant from diagnosis through survivorship by providing vital information and personalized support services.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anaplastic Large Cell Lymphoma" for support, advocacy or research.

National Bone Marrow Transplant Link

The mission of the National Bone Marrow Transplant Link is to help patients, caregivers, and families cope with the social and emotional challenges of bone marrow/stem cell transplant from diagnosis through survivorship by providing vital information and personalized support services.

http://www.nbmtlink.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anaplastic Large Cell Lymphoma" returned 292 free, full-text research articles on human participants. First 3 results:

Activating mutations in ALK kinase domain confer resistance to structurally unrelated ALK inhibitors in NPM-ALK-positive anaplastic large-cell lymphoma.
 

Author(s): Daria Zdzalik, Barbara Dymek, Paulina Grygielewicz, Pawel Gunerka, Anna Bujak, Monika Lamparska-Przybysz, Maciej Wieczorek, Karolina Dzwonek

Journal: J. Cancer Res. Clin. Oncol.. 2014 Apr;140(4):589-98.

 

Crizotinib, the first FDA-approved ALK inhibitor, showed significant antitumor activity in young patients with anaplastic large-cell lymphoma (ALCL) frequently displaying ALK rearrangement. However, long-term therapeutic benefits of crizotinib are limited due to development of drug ...

Last Updated: 11 Mar 2014

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Anaplastic large cell lymphoma of the colon in a patient with colonic Crohn disease treated with infliximab and methotrexate.
 

Author(s): Tushar Shukla, Jennifer Jin, Esmeralda Celia Marginean, Nav Saloojee

Journal: Can J Gastroenterol Hepatol. 2014 Jan;28(1):11-2.

 

Last Updated: 13 Jan 2014

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Refractory case of ALK-negative anaplastic large-cell lymphoma with PAX-5 expression and T-cell receptor-γ gene rearrangement.
 

Author(s): Keiki Kawakami, Akira Yazaki, Ryugo Ito, Yasutaka Tono, Tetsuya Murata, Yohichiro Baba, Tomoko Uchiyama, Hiroshi Imai, Shigeo Nakamura

Journal: J Clin Exp Hematop. 2013 ;53(3):251-4.

 

Last Updated: 26 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anaplastic Large Cell Lymphoma" returned 27 free, full-text review articles on human participants. First 3 results:

ALK-negative anaplastic large cell lymphoma primarily involving the bronchus: a case report and literature review.
 

Author(s): Xiangdong Xu

Journal:

 

Anaplastic large cell lymphoma (ALCL) is a mature T cell lymphoma with characteristic morphologic, immunophenotypic and cytogenetic features. Current WHO classification includes anaplastic lymphoma kinase (ALK)-positive and ALK-negative variants. ALCL rarely presents with obstructive ...

Last Updated: 15 Jan 2014

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Beyond NPM-anaplastic lymphoma kinase driven lymphomagenesis: alternative drivers in anaplastic large cell lymphoma.
 

Author(s): Fabrizio Tabbò, Maurilio Ponzoni, Raul Rabadan, Francesco Bertoni, Giorgio Inghirami,

Journal: Curr. Opin. Hematol.. 2013 Jul;20(4):374-81.

 

Anaplastic large cell lymphomas (ALCLs) are rare entities whose somatic genetic lesions have been identified only in a subset of patients. Thus, an integrated and massive discovery programme is required to define their tumourigenic alterations and to design more successful tailored therapies.

Last Updated: 6 Jun 2013

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Anaplastic large cell lymphoma, ALK-negative.
 

Author(s): Andrés J M Ferreri, Silvia Govi, Stefano A Pileri, Kerry J Savage

Journal: Crit. Rev. Oncol. Hematol.. 2013 Feb;85(2):206-15.

 

Anaplastic large cell lymphoma (ALCL), anaplastic lymphoma kinase (ALK)-negative (ALCL-ALK-) is a provisional entity in the WHO 2008 Classification that represents 2-3% of NHL and 12% of T-cell NHL. No particular risk factor has been clearly identified for ALCL, but a recent study ...

Last Updated: 23 Jan 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Brentuximab Vedotin or Crizotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II-IV Anaplastic Large Cell Lymphoma
 

Status: Recruiting

Condition Summary: Stage II Childhood Anaplastic Large Cell Lymphoma; Stage III Childhood Anaplastic Large Cell Lymphoma; Stage IV Childhood Anaplastic Large Cell Lymphoma

 

Last Updated: 22 Oct 2014

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Brentuximab Vedotin and Bendamustine for the Treatment of Hodgkin Lymphoma and Anaplastic Large Cell Lymphoma (ALCL)
 

Status: Recruiting

Condition Summary: Hodgkin Lymphoma; Anaplastic Large Cell Lymphoma

 

Last Updated: 9 Apr 2014

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A Phase 1 Study in Patients With Relapsed or Refractory Hodgkin Lymphoma or Systemic Anaplastic Large Cell Lymphoma
 

Status: Recruiting

Condition Summary: Hodgkin Lymphoma; Anaplastic Large-cell Lymphoma

 

Last Updated: 15 Jan 2014

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