Leptospirosis

Common Name(s)

Leptospirosis

Leptospirosis is an infectious bacterial disease that affects both humans and animals. Humans become infected through direct contact with the urine of infected animals or through urine-contaminated environments, where the bacteria enter into the system through cuts and abrasions of the skin or through the eyes, nose, and mouth. Leptospirosis occurs worldwide, but is most prevalent in tropical and subtropical regions, with outbreaks common following excessive rainfall or flooding. Signs and symptoms of leptospirosis can range from a mild flu-like illness to a more serious and sometimes fatal disease. In the early stages, symptoms include high fever, severe headache, muscle pain, chills, redness of the eyes, hives, abdominal pain, jaundice, hemorrhages in the skin, vomiting, diarrhea, and rash.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leptospirosis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leptospirosis" returned 665 free, full-text research articles on human participants. First 3 results:

Seroprevalence of and risk factors for leptospirosis in the City of Manaus, State of Amazonas, Brazil.
 

Author(s): Luciete Almeida Silva, Kátia Maria da Silva Lima, Ormezinda Celeste Cristo Fernandes, Ilana Teruszkin Balassiano, Kátia Eliane Santos Avelar, Michele Silva de Jesus

Journal: Rev. Soc. Bras. Med. Trop.. ;49(5):628-631.

 

Leptospirosis is caused by a bacterium of the genus Leptospira. This study aimed at investigating the seroprevalence of and risk factors for leptospirosis in humans in Manaus, State of Amazonas.

Last Updated: 4 Nov 2016

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Antibodies for Rickettsia spp. in patients with negative serology for dengue virus, leptospirosis, and meningococcal disease in municipalities of São Paulo State, Brazil.
 

Author(s): Juliana Anacleto Cabral Prata, Celso Eduardo de Souza, Rodrigo Nogueira Angerami, Taíse Marongio Cotrim de Moraes Barbosa, Fabiana Cristina Pereira Dos Santos, Silvia Colombo, Vânia Martins Fontes Del Guercio, Maria Rita Donalísio

Journal: Rev. Soc. Bras. Med. Trop.. ;49(5):567-571.

 

Brazilian spotted fever is an infectious disease with a high mortality rate if not treated early. Differential diagnosis is difficult, as the first clinical signs are non-specific and can be confused with other diseases. The aim of the study was to investigate evidence of infection ...

Last Updated: 4 Nov 2016

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A case-control study of epidemiological factors associated with leptospirosis in South Gujarat region.
 

Author(s): K T Desai, F Patel, P B Patel, S Nayak, N B Patel, R K Bansal

Journal: J Postgrad Med. ;62(4):223-227.

 

The current study was planned to identify the epidemiological factors associated with leptospirosis in South Gujarat region using neighborhood controls.

Last Updated: 20 Oct 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leptospirosis" returned 65 free, full-text review articles on human participants. First 3 results:

Global Morbidity and Mortality of Leptospirosis: A Systematic Review.
 

Author(s): Federico Costa, José E Hagan, Juan Calcagno, Michael Kane, Paul Torgerson, Martha S Martinez-Silveira, Claudia Stein, Bernadette Abela-Ridder, Albert I Ko

Journal:

 

Leptospirosis, a spirochaetal zoonosis, occurs in diverse epidemiological settings and affects vulnerable populations, such as rural subsistence farmers and urban slum dwellers. Although leptospirosis is a life-threatening disease and recognized as an important cause of pulmonary ...

Last Updated: 18 Sep 2015

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Environmental and Behavioural Determinants of Leptospirosis Transmission: A Systematic Review.
 

Author(s): Mwanajaa Abdalla Mwachui, Lisa Crump, Rudy Hartskeerl, Jakob Zinsstag, Jan Hattendorf

Journal:

 

Leptospirosis is one of the most widespread zoonotic diseases, which is of global medical and veterinary importance, and also a re-emerging infectious disease. The main tracks of transmission are known; however, the relative importance of each of the components and the respective ...

Last Updated: 18 Sep 2015

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Epidemiology of Leptospirosis in Africa: A Systematic Review of a Neglected Zoonosis and a Paradigm for 'One Health' in Africa.
 

Author(s): Kathryn J Allan, Holly M Biggs, Jo E B Halliday, Rudovick R Kazwala, Venance P Maro, Sarah Cleaveland, John A Crump

Journal:

 

Leptospirosis is an important but neglected bacterial zoonosis that has been largely overlooked in Africa. In this systematic review, we aimed to summarise and compare current knowledge of: (1) the geographic distribution, prevalence, incidence and diversity of acute human leptospirosis ...

Last Updated: 15 Sep 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

French West Indies Leptospirosis Study
 

Status: Recruiting

Condition Summary: Leptospirosis

 

Last Updated: 29 Feb 2016

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Immune Response After Leptospirosis Infection
 

Status: Not yet recruiting

Condition Summary: Leptospirosis

 

Last Updated: 8 Sep 2016

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Last Updated: 29 Feb 2016

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