Leptospirosis

Common Name(s)

Leptospirosis

Leptospirosis is an infectious bacterial disease that affects both humans and animals. Humans become infected through direct contact with the urine of infected animals or through urine-contaminated environments, where the bacteria enter into the system through cuts and abrasions of the skin or through the eyes, nose, and mouth. Leptospirosis occurs worldwide, but is most prevalent in tropical and subtropical regions, with outbreaks common following excessive rainfall or flooding. Signs and symptoms of leptospirosis can range from a mild flu-like illness to a more serious and sometimes fatal disease. In the early stages, symptoms include high fever, severe headache, muscle pain, chills, redness of the eyes, hives, abdominal pain, jaundice, hemorrhages in the skin, vomiting, diarrhea, and rash.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leptospirosis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leptospirosis" returned 622 free, full-text research articles on human participants. First 3 results:

Characteristics of leptospirosis with systemic inflammatory response syndrome: a multicenter study.
 

Author(s): Hava Yilmaz, Vedat Turhan, Kadriye Kart Yasar, Mustafa Hatipoglu, Mustafa Sunbul, Hakan Leblebicioglu

Journal:

 

Leptospirosis is a common zoonotic infection in the world. In patients with leptospirosis, in case of presence of Systemic Inflammatory Response Syndrome (SIRS), clinical and laboratory findings can be mistaken for sepsis due to other causes of infection. The purpose of this study ...

Last Updated: 22 Dec 2015

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Leptospira Serovars for Diagnosis of Leptospirosis in Humans and Animals in Africa: Common Leptospira Isolates and Reservoir Hosts.
 

Author(s): Georgies F Mgode, Robert S Machang'u, Ginethon G Mhamphi, Abdul Katakweba, Loth S Mulungu, Lies Durnez, Herwig Leirs, Rudy A Hartskeerl, Steven R Belmain

Journal:

 

The burden of leptospirosis in humans and animals in Africa is higher than that reported from other parts of the world. However, the disease is not routinely diagnosed in the continent. One of major factors limiting diagnosis is the poor availability of live isolates of locally circulating ...

Last Updated: 2 Dec 2015

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A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
 

Author(s): Raissa Matos Fontes, Luciano Pamplona de Góes Cavalcanti, Augusto César Aragão Oliveira, Laiane Fernanda de Melo Bezerra, Almira Maria Monteiro Gomes, Jeová Keny Baima Colares, Danielle Malta Lima

Journal: Rev. Inst. Med. Trop. Sao Paulo. ;57(5):443-6.

 

Leptospirosis is a febrile disease with a typically underestimated global incidence, especially in regions where dengue is endemic. Therefore, it is difficult to accurately determine the number of leptospirosis cases in these areas, which contributes to significant under-reporting ...

Last Updated: 25 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leptospirosis" returned 65 free, full-text review articles on human participants. First 3 results:

Global Morbidity and Mortality of Leptospirosis: A Systematic Review.
 

Author(s): Federico Costa, José E Hagan, Juan Calcagno, Michael Kane, Paul Torgerson, Martha S Martinez-Silveira, Claudia Stein, Bernadette Abela-Ridder, Albert I Ko

Journal:

 

Leptospirosis, a spirochaetal zoonosis, occurs in diverse epidemiological settings and affects vulnerable populations, such as rural subsistence farmers and urban slum dwellers. Although leptospirosis is a life-threatening disease and recognized as an important cause of pulmonary ...

Last Updated: 18 Sep 2015

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Environmental and Behavioural Determinants of Leptospirosis Transmission: A Systematic Review.
 

Author(s): Mwanajaa Abdalla Mwachui, Lisa Crump, Rudy Hartskeerl, Jakob Zinsstag, Jan Hattendorf

Journal:

 

Leptospirosis is one of the most widespread zoonotic diseases, which is of global medical and veterinary importance, and also a re-emerging infectious disease. The main tracks of transmission are known; however, the relative importance of each of the components and the respective ...

Last Updated: 18 Sep 2015

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Epidemiology of Leptospirosis in Africa: A Systematic Review of a Neglected Zoonosis and a Paradigm for 'One Health' in Africa.
 

Author(s): Kathryn J Allan, Holly M Biggs, Jo E B Halliday, Rudovick R Kazwala, Venance P Maro, Sarah Cleaveland, John A Crump

Journal:

 

Leptospirosis is an important but neglected bacterial zoonosis that has been largely overlooked in Africa. In this systematic review, we aimed to summarise and compare current knowledge of: (1) the geographic distribution, prevalence, incidence and diversity of acute human leptospirosis ...

Last Updated: 15 Sep 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

French West Indies Leptospirosis Study
 

Status: Recruiting

Condition Summary: Leptospirosis

 

Last Updated: 29 Feb 2016

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Last Updated: 29 Feb 2016

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