Leptospirosis

Common Name(s)

Leptospirosis

Leptospirosis is an infectious bacterial disease that affects both humans and animals. Humans become infected through direct contact with the urine of infected animals or through urine-contaminated environments, where the bacteria enter into the system through cuts and abrasions of the skin or through the eyes, nose, and mouth. Leptospirosis occurs worldwide, but is most prevalent in tropical and subtropical regions, with outbreaks common following excessive rainfall or flooding. Signs and symptoms of leptospirosis can range from a mild flu-like illness to a more serious and sometimes fatal disease. In the early stages, symptoms include high fever, severe headache, muscle pain, chills, redness of the eyes, hives, abdominal pain, jaundice, hemorrhages in the skin, vomiting, diarrhea, and rash.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leptospirosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leptospirosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leptospirosis" returned 687 free, full-text research articles on human participants. First 3 results:

Temporal analysis of the relationship between leptospirosis, rainfall levels and seasonality, Santa Catarina, Brazil, 2005-2015.
 

Author(s): João Ghizzo Filho, Nazaré Otília Nazário, Paulo Fontoura Freitas, Gustavo de Araújo Pinto, Aline Daiane Schlindwein

Journal:

 

The objective of the study is to analyze the temporal trend of leptospirosis incidence, according to rainfall levels in Santa Catarina, according to seasonality, from 2005 to 2015. This is an ecological study of time series, with date of leptospirosis, rainfall levels and population. ...

Last Updated: 31 Dec 1969

Go To URL
Socio-epidemiological characterization of human leptospirosis in the Federal District, Brazil, 2011-2015.
 

Author(s): Ivanildo de Oliveira Correia Santos, Marina Frota de Albuquerque Landi, Eduardo Maurício Mendes de Lima, Laurício Monteiro Cruz, Maria Isabel Rao Bofill, Divino Eterno Dos Santos, Márcio Botelho de Castro

Journal: Rev. Soc. Bras. Med. Trop.. ;51(3):372-375.

 

Human leptospirosis (HL) in the Federal District (DF), Brazil, is endemic and requires studies to characterize the socio-epidemiological profile of the vulnerable population.

Last Updated: 31 Dec 1969

Go To URL
Risk factors for human acute leptospirosis in northern Tanzania.
 

Author(s): Michael J Maze, Shama Cash-Goldwasser, Matthew P Rubach, Holly M Biggs, Renee L Galloway, Katrina J Sharples, Kathryn J Allan, Jo E B Halliday, Sarah Cleaveland, Michael C Shand, Charles Muiruri, Rudovick R Kazwala, Wilbrod Saganda, Bingileki F Lwezaula, Blandina T Mmbaga, Venance P Maro, John A Crump

Journal:

 

Leptospirosis is a major cause of febrile illness in Africa but little is known about risk factors for human infection. We conducted a cross-sectional study to investigate risk factors for acute leptospirosis and Leptospira seropositivity among patients with fever attending referral ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leptospirosis" returned 70 free, full-text review articles on human participants. First 3 results:

Pathology and pathogenesis of human leptospirosis: a commented review.
 

Author(s): Thales De Brito, Ana Maria Gonçalves da Silva, Patrícia Antonia Estima Abreu

Journal: Rev. Inst. Med. Trop. Sao Paulo. 2018 ;60():e23.

 

Leptospirosis is an acute bacterial septicemic febrile disease caused by pathogenic leptospires, which affect humans and animals in all parts of the world. Transmission can occur by direct contact with infected animals or, more commonly, through indirect contact with water or soil ...

Last Updated: 31 Dec 1969

Go To URL
A systematic review of human and animal leptospirosis in the Pacific Islands reveals pathogen and reservoir diversity.
 

Author(s): Vanina Guernier, Cyrille Goarant, Jackie Benschop, Colleen L Lau

Journal:

 

The Pacific Islands have environmental conditions highly favourable for transmission of leptospirosis, a neglected zoonosis with highest incidence in the tropics, and Oceania in particular. Recent reports confirm the emergence and outbreaks of leptospirosis in the Pacific Islands, ...

Last Updated: 31 Dec 1969

Go To URL
IgM ELISA for leptospirosis diagnosis: a systematic review and meta-analysis.
 

Author(s): Maria Ines Rosa, Maria Fernandes Dos Reis, Carla Simon, Eduardo Dondossola, Maria Cecília Alexandre, Tamy Colonetti, Fernanda Oliveira Meller

Journal: Cien Saude Colet. 2017 Dec;22(12):4001-4012.

 

A systematic review with meta-analysis was performed to estimate the accuracy of IgM ELISA for Leptospirosis diagnosis. A search of Medline, Lilacs, Embase, Cochrane Central Register of Controlled Trials and Grey literature (Google Scholar and British Library) was conducted. The medical ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 19 Mar 2018

Go to URL