Leptospirosis

Common Name(s)

Leptospirosis

Leptospirosis is an infectious bacterial disease that affects both humans and animals. Humans become infected through direct contact with the urine of infected animals or through urine-contaminated environments, where the bacteria enter into the system through cuts and abrasions of the skin or through the eyes, nose, and mouth. Leptospirosis occurs worldwide, but is most prevalent in tropical and subtropical regions, with outbreaks common following excessive rainfall or flooding. Signs and symptoms of leptospirosis can range from a mild flu-like illness to a more serious and sometimes fatal disease. In the early stages, symptoms include high fever, severe headache, muscle pain, chills, redness of the eyes, hives, abdominal pain, jaundice, hemorrhages in the skin, vomiting, diarrhea, and rash.

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Condition Specific Organizations

Following organizations serve the condition "Leptospirosis" for support, advocacy or research.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leptospirosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leptospirosis" returned 629 free, full-text research articles on human participants. First 3 results:

Evaluation of different serological assays for early diagnosis of leptospirosis in Martinique (French West Indies).
 

Author(s): Christophe Courdurie, Yohann Le Govic, Pascale Bourhy, Dorothee Alexer, Karine Pailla, Rafaelle Theodose, Raymond Cesaire, Jacques Rosine, Patrick Hochedez, Claude Olive

Journal:

 

Leptospirosis is a potentially life-threatening but curable zoonosis whose prognosis depends on accurate and timely diagnosis. Because of its non-specific clinical presentation, laboratory testing is essential to confirm the diagnosis. Here, we aimed to assess the performance of two ...

Last Updated: 23 Jun 2017

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Rat infestation associated with environmental deficiencies in an urban slum community with high risk of leptospirosis transmission.
 

Author(s): Norlan de Jesus Santos, Erica Sousa, Mitermayer G Reis, Albert I Ko, Federico Costa

Journal:

 

We analyzed environmental factors that provide food, water and harborage to rodents and the risk of household rodent infestation in a slum community with a high risk of leptospirosis transmission. Detailed environmental surveys were performed in 221 households. Multivariate regression ...

Last Updated: 16 Mar 2017

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Seeking the environmental source of Leptospirosis reveals durable bacterial viability in river soils.
 

Author(s): Roman Thibeaux, Sophie Geroult, Claire Benezech, Stéphane Chabaud, Marie-Estelle Soupé-Gilbert, Dominique Girault, Emilie Bierque, Cyrille Goarant

Journal:

 

Leptospirosis is an important re-emerging infectious disease that affects humans worldwide. Infection occurs from indirect environment-mediated exposure to pathogenic leptospires through contaminated watered environments. The ability of pathogenic leptospires to persist in the aqueous ...

Last Updated: 27 Feb 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leptospirosis" returned 61 free, full-text review articles on human participants. First 3 results:

Micronutrients and Leptospirosis: A Review of the Current Evidence.
 

Author(s): Heather S Herman, Saurabh Mehta, Washington B Cárdenas, Anna M Stewart-Ibarra, Julia L Finkelstein

Journal:

 

Leptospirosis is one of the most widespread zoonoses and represents a major threat to human health. Due to the high burden of disease, limitations in diagnostics, and limited coverage and availability of effective human and veterinary vaccines, leptospirosis remains an important neglected ...

Last Updated: 8 Jul 2016

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Global Morbidity and Mortality of Leptospirosis: A Systematic Review.
 

Author(s): Federico Costa, José E Hagan, Juan Calcagno, Michael Kane, Paul Torgerson, Martha S Martinez-Silveira, Claudia Stein, Bernadette Abela-Ridder, Albert I Ko

Journal:

 

Leptospirosis, a spirochaetal zoonosis, occurs in diverse epidemiological settings and affects vulnerable populations, such as rural subsistence farmers and urban slum dwellers. Although leptospirosis is a life-threatening disease and recognized as an important cause of pulmonary ...

Last Updated: 18 Sep 2015

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Environmental and Behavioural Determinants of Leptospirosis Transmission: A Systematic Review.
 

Author(s): Mwanajaa Abdalla Mwachui, Lisa Crump, Rudy Hartskeerl, Jakob Zinsstag, Jan Hattendorf

Journal:

 

Leptospirosis is one of the most widespread zoonotic diseases, which is of global medical and veterinary importance, and also a re-emerging infectious disease. The main tracks of transmission are known; however, the relative importance of each of the components and the respective ...

Last Updated: 18 Sep 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

French West Indies Leptospirosis Study
 

Status: Recruiting

Condition Summary: Leptospirosis

 

Last Updated: 29 Feb 2016

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Immune Response After Leptospirosis Infection
 

Status: Not yet recruiting

Condition Summary: Leptospirosis

 

Last Updated: 8 Sep 2016

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Last Updated: 29 Feb 2016

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