Leptospirosis

Common Name(s)

Leptospirosis

Leptospirosis is an infectious bacterial disease that affects both humans and animals. Humans become infected through direct contact with the urine of infected animals or through urine-contaminated environments, where the bacteria enter into the system through cuts and abrasions of the skin or through the eyes, nose, and mouth. Leptospirosis occurs worldwide, but is most prevalent in tropical and subtropical regions, with outbreaks common following excessive rainfall or flooding. Signs and symptoms of leptospirosis can range from a mild flu-like illness to a more serious and sometimes fatal disease. In the early stages, symptoms include high fever, severe headache, muscle pain, chills, redness of the eyes, hives, abdominal pain, jaundice, hemorrhages in the skin, vomiting, diarrhea, and rash.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leptospirosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leptospirosis" returned 638 free, full-text research articles on human participants. First 3 results:

Early Indicators of Fatal Leptospirosis during the 2010 Epidemic in Puerto Rico.
 

Author(s): Tyler M Sharp, Brenda Rivera García, Janice Pérez-Padilla, Renee L Galloway, Marta Guerra, Kyle R Ryff, Dana Haberling, Sharada Ramakrishnan, Sean Shadomy, Dianna Blau, Kay M Tomashek, William A Bower

Journal:

 

Leptospirosis is a potentially fatal bacterial zoonosis that is endemic throughout the tropics and may be misdiagnosed as dengue. Delayed hospital admission of leptospirosis patients is associated with increased mortality.

Last Updated: 26 Feb 2016

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Expression Profile of Cytokines and Enzymes mRNA in Blood Leukocytes of Dogs with Leptospirosis and Its Associated Pulmonary Hemorrhage Syndrome.
 

Author(s): Carla A Maissen-Villiger, Ariane Schweighauser, H Anette van Dorland, Claudine Morel, Rupert M Bruckmaier, Andreas Zurbriggen, Thierry Francey

Journal:

 

Dogs with leptospirosis show similar organ manifestations and disease course as human patients, including acute kidney injury and pulmonary hemorrhage, making this naturally-occurring infection a good animal model for human leptospirosis. Expression patterns of cytokines and enzymes ...

Last Updated: 30 Jan 2016

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Human Leptospirosis Infection in Fiji: An Eco-epidemiological Approach to Identifying Risk Factors and Environmental Drivers for Transmission.
 

Author(s): Colleen L Lau, Conall H Watson, John H Lowry, Michael C David, Scott B Craig, Sarah J Wynwood, Mike Kama, Eric J Nilles

Journal:

 

Leptospirosis is an important zoonotic disease in the Pacific Islands. In Fiji, two successive cyclones and severe flooding in 2012 resulted in outbreaks with 576 reported cases and 7% case-fatality. We conducted a cross-sectional seroprevalence study and used an eco-epidemiological ...

Last Updated: 29 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leptospirosis" returned 66 free, full-text review articles on human participants. First 3 results:

Global Morbidity and Mortality of Leptospirosis: A Systematic Review.
 

Author(s): Federico Costa, José E Hagan, Juan Calcagno, Michael Kane, Paul Torgerson, Martha S Martinez-Silveira, Claudia Stein, Bernadette Abela-Ridder, Albert I Ko

Journal:

 

Leptospirosis, a spirochaetal zoonosis, occurs in diverse epidemiological settings and affects vulnerable populations, such as rural subsistence farmers and urban slum dwellers. Although leptospirosis is a life-threatening disease and recognized as an important cause of pulmonary ...

Last Updated: 18 Sep 2015

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Environmental and Behavioural Determinants of Leptospirosis Transmission: A Systematic Review.
 

Author(s): Mwanajaa Abdalla Mwachui, Lisa Crump, Rudy Hartskeerl, Jakob Zinsstag, Jan Hattendorf

Journal:

 

Leptospirosis is one of the most widespread zoonotic diseases, which is of global medical and veterinary importance, and also a re-emerging infectious disease. The main tracks of transmission are known; however, the relative importance of each of the components and the respective ...

Last Updated: 18 Sep 2015

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Epidemiology of Leptospirosis in Africa: A Systematic Review of a Neglected Zoonosis and a Paradigm for 'One Health' in Africa.
 

Author(s): Kathryn J Allan, Holly M Biggs, Jo E B Halliday, Rudovick R Kazwala, Venance P Maro, Sarah Cleaveland, John A Crump

Journal:

 

Leptospirosis is an important but neglected bacterial zoonosis that has been largely overlooked in Africa. In this systematic review, we aimed to summarise and compare current knowledge of: (1) the geographic distribution, prevalence, incidence and diversity of acute human leptospirosis ...

Last Updated: 15 Sep 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

French West Indies Leptospirosis Study
 

Status: Recruiting

Condition Summary: Leptospirosis

 

Last Updated: 29 Feb 2016

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Last Updated: 29 Feb 2016

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