Leptospirosis

Common Name(s)

Leptospirosis

Leptospirosis is an infectious bacterial disease that affects both humans and animals. Humans become infected through direct contact with the urine of infected animals or through urine-contaminated environments, where the bacteria enter into the system through cuts and abrasions of the skin or through the eyes, nose, and mouth. Leptospirosis occurs worldwide, but is most prevalent in tropical and subtropical regions, with outbreaks common following excessive rainfall or flooding. Signs and symptoms of leptospirosis can range from a mild flu-like illness to a more serious and sometimes fatal disease. In the early stages, symptoms include high fever, severe headache, muscle pain, chills, redness of the eyes, hives, abdominal pain, jaundice, hemorrhages in the skin, vomiting, diarrhea, and rash.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leptospirosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leptospirosis" returned 493 free, full-text research articles on human participants. First 3 results:

An outbreak of leptospirosis in Lezhi County, China in 2010 may possibly be linked to rainfall.
 

Author(s): Ya Lin Wang, Jin Hong Qin, Cui Cai Zhang, Xiao Kui Guo, Xiu Gao Jiang, Ping He

Journal: Biomed. Environ. Sci.. 2014 Jan;27(1):56-9.

 

Last Updated: 20 Feb 2014

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Association of angiopoietin-2 and dimethylarginines with complicated course in patients with leptospirosis.
 

Author(s): Alexander Lukasz, Bodo Hoffmeister, Barbara Graf, Benno Wölk, Karsten Noeckler, Stefanie M Bode-Böger, Johannes Hadem, Sven Pischke, Jan T Kielstein

Journal:

 

Leptospirosis is one of the most relevant zoonosis worldwide and a potentially life-threatening infectious disease. While it is frequent in tropic regions, it is uncommon in European industrialized countries. Angiopoietin-2 (Angpt-2) and asymmetric and symmetric dimethylarginine (ADMA ...

Last Updated: 5 Feb 2014

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Two cases of laboratory-confirmed leptospirosis in travellers returning to Spain from Thailand, September 2013.
 

Author(s): A Calvo-Cano, E Aldasoro, Mf Ramirez, Mj Martinez, A Requena-Mendez, J Gascon

Journal:

 

In September 2013, leptospirosis was diagnosed in two Spanish travellers returning from Thailand. The first case walked in floodwater in the Phi Phi Islands in pouring rain: 20 days later he presented with fever and acute hepatitis. The second presented with fever and renal failure ...

Last Updated: 24 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leptospirosis" returned 43 free, full-text review articles on human participants. First 3 results:

Leptospirosis, an emerging zoonotic disease in Malaysia.
 

Author(s): S Thayaparan, I D Robertson, A Fairuz, L Suut, M T Abdullah

Journal: Malays J Pathol. 2013 Dec;35(2):123-32.

 

Leptospirosis is an endemic disease in Malaysia and recently has received increasing attention mainly due to several recent incidents that have resulted in human mortality which have alarmed health professionals in Malaysia. The increasing incidence of leptospirosis in forested regions ...

Last Updated: 23 Dec 2013

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Leptospirosis in the western Indian Ocean islands: what is known so far?
 

Author(s): Amélie Desvars, Alain Michault, Pascale Bourhy

Journal:

 

In the past decade, leptospirosis has emerged as a major zoonosis with a worldwide distribution. The disease is caused by bacteria of the genus Leptospira. The western Indian Ocean includes more than one hundred tropical or subequatorial islands where leptospirosis constitutes a major ...

Last Updated: 15 Nov 2013

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Leptospirosis--current risk factors connected with human activity and the environment.
 

Author(s): Bernard Wasiński, Jacek Dutkiewicz

Journal: Ann Agric Environ Med. 2013 ;20(2):239-44.

 

Leptospirosis is a widespread although recently neglected zoonosis recognized worldwide. The disease seems to be underestimated, especially in countries located in the temperate climatic zone. The presented article concerns the main characteristics of leptospirosis and describes formerly ...

Last Updated: 18 Jun 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

French West Indies Leptospirosis Study
 

Status: Recruiting

Condition Summary: Leptospirosis

 

Last Updated: 25 May 2012

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Last Updated: 27 Nov 2013

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Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)
 

Status: Recruiting

Condition Summary: Visceral Leishmaniasis; Human African Trypanosomiasis; Enteric Fever; Melioidosis; Brucellosis; Leptospirosis; Relapsing Fever; Rickettsial Diseases; HIV; Tuberculosis; Malaria; Amoebic Liver Abscess

 

Last Updated: 12 Sep 2014

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