Leishmaniasis

Common Name(s)

Leishmaniasis

Leishmaniasis is a parasitic disease spread by the bite of infected sand flies. There are several different forms of leishmaniasis. The most common are cutaneous and visceral. The cutaneous type causes skin sores. The visceral type affects internal organs such as the spleen, liver and bone marrow. People with this form usually have fever, weight loss, and an enlarged spleen and liver. Visceral disease can be deadly without proper treatment. Leishmaniasis is found in parts of the Middle East, Central America, South American, Asia, Africa, and southern Europe. Most of these countries are in the tropics and subtropics. It is possible but very unlikely to get this disease in the United States.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leishmaniasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leishmaniasis" returned 1949 free, full-text research articles on human participants. First 3 results:

Skin Scraping is the Most Accessible Technique for the Parasitological Diagnosis of American Tegumentary Leishmaniasis.
 

Author(s): Cintia X de Mello, Maria de Fátima Madeira

Journal: Am. J. Trop. Med. Hyg.. 2015 May;92(5):1082.

 

Last Updated: 7 May 2015

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Spatial distribution and cluster analysis of a leishmaniasis outbreak in the south-western Madrid region, Spain, September 2009 to April 2013.
 

Author(s): D Gomez-Barroso, Z Herrador, J V San Martin, A Gherasim, M Aguado, A Romero-Mate, L Molina, P Aparicio, A Benito

Journal:

 

Last Updated: 27 Feb 2015

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Historical series of patients with visceral leishmaniasis treated with meglumine antimoniate in a hospital for tropical diseases, Maceió-AL, Brazil.
 

Author(s): Lindon Johoson Diniz Silveira, Thiago José Matos Rocha, Sandra Aparecida Ribeiro, Célia Maria Silva Pedrosa

Journal: Rev. Inst. Med. Trop. Sao Paulo. ;57(1):33-8.

 

Visceral leishmaniasis is an endemic protozoan found in Brazil. It is characterized by fever, pallor, hepatosplenomegaly, lymphadenopathy, and progressive weakness in the patient. It may lead to death if untreated. The drug of choice for treatment is meglumine antimoniate (Glucantime). ...

Last Updated: 5 Feb 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leishmaniasis" returned 175 free, full-text review articles on human participants. First 3 results:

Leishmaniasis in Uganda: historical account and a review of the literature.
 

Author(s): Joseph Olobo-Okao, Patrick Sagaki

Journal:

 

Visceral leishmaniasis (VL) or kala azar is a fatal and neglected disease caused by protozoan parasites. It occurs worldwide including north-eastern Uganda. This review gives a historical account of and reviews available literature on VL in Uganda to raise more awareness about the ...

Last Updated: 31 Oct 2014

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Low quality evidence of epidemiological observational studies on leishmaniasis in Brazil.
 

Author(s): Bruno Trentini, Mário Steindel, Mariel A Marlow

Journal:

 

Brazil has implemented systematic control methods for leishmaniasis for the past 30 years, despite an increase in cases and continued spread of the disease to new regions. A lack high quality evidence from epidemiological observational studies impedes the development of novel control ...

Last Updated: 9 Sep 2014

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Complementary exams in the diagnosis of American tegumentary leishmaniasis.
 

Author(s): Ciro Martins Gomes, Natália Aparecida de Paula, Orlando Oliveira de Morais, Killarney Ataíde Soares, Ana Maria Roselino, Raimunda Nonata Ribeiro Sampaio

Journal: An Bras Dermatol. ;89(5):701-9.

 

The diagnosis of American Tegumentary Leishmaniasis is a difficult but essential task when considering the high toxicity profile of the drugs available. Since the discovery of its etiologic agent, numerous diagnostic tests have been developed. None of the tests available today can ...

Last Updated: 4 Sep 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Low Antimonial Dosage in American Mucosal Leishmaniasis
 

Status: Recruiting

Condition Summary: Mucosal Leishmaniasis; Mucocutaneous Leishmaniasis

 

Last Updated: 17 Jun 2015

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Compassionate Use of Sodium Stibogluconate (Pentostam) for Cutaneous and Mucocutaneous New World Leishmaniasis
 

Status: Available

Condition Summary: Leishmaniasis, Cutaneous; Leishmaniasis, Mucocutaneous

 

Last Updated: 12 Dec 2014

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Dedicated QT Study in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous Leishmaniasis
 

Status: Not yet recruiting

Condition Summary: Mucocutaneous Leishmaniasis

 

Last Updated: 24 Apr 2015

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