Leishmaniasis

Common Name(s)

Leishmaniasis

Leishmaniasis is a parasitic disease spread by the bite of infected sand flies. There are several different forms of leishmaniasis. The most common are cutaneous and visceral. The cutaneous type causes skin sores. The visceral type affects internal organs such as the spleen, liver and bone marrow. People with this form usually have fever, weight loss, and an enlarged spleen and liver. Visceral disease can be deadly without proper treatment. Leishmaniasis is found in parts of the Middle East, Central America, South American, Asia, Africa, and southern Europe. Most of these countries are in the tropics and subtropics. It is possible but very unlikely to get this disease in the United States.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leishmaniasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leishmaniasis" returned 1960 free, full-text research articles on human participants. First 3 results:

Skin Scraping is the Most Accessible Technique for the Parasitological Diagnosis of American Tegumentary Leishmaniasis.
 

Author(s): Cintia X de Mello, Maria de Fátima Madeira

Journal: Am. J. Trop. Med. Hyg.. 2015 May;92(5):1082.

 

Last Updated: 7 May 2015

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Spatial distribution and cluster analysis of a leishmaniasis outbreak in the south-western Madrid region, Spain, September 2009 to April 2013.
 

Author(s): D Gomez-Barroso, Z Herrador, J V San Martin, A Gherasim, M Aguado, A Romero-Mate, L Molina, P Aparicio, A Benito

Journal:

 

Last Updated: 27 Feb 2015

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[Comparison of direct microscopy, culture and polymerase chain reaction methods for the diagnosis of cutaneous leishmaniasis].
 

Author(s): Hatice Ertabaklar, Serçin Özlem Çalışkan, Erengül Boduç, Sema Ertuğ

Journal: Mikrobiyol Bul. 2015 Jan;49(1):77-84.

 

Cutaneous leishmaniasis (CL) is an endemic disease especially in Southeastern Anatolia of Turkey and recently shows a trend for spread to other regions of the country including the Aegean region. The diagnosis of CL is based on combined evaluation of epidemiological data with the ...

Last Updated: 24 Feb 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leishmaniasis" returned 176 free, full-text review articles on human participants. First 3 results:

Health economic evaluations of visceral leishmaniasis treatments: a systematic review.
 

Author(s): Daniel S Marinho, Carmen N P R Casas, Claudia C de A Pereira, Iuri C Leite

Journal:

 

The main objective of this study was to identify, describe, classify and analyze the scientific health economic evidence of VL-related technologies.

Last Updated: 28 Feb 2015

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Case report: visceral leishmaniasis diagnosed by biopsy of an axillary lymph node: case report and literature review.
 

Author(s): Z Z Liu, X J Lv

Journal:

 

A 56-year-old man presented with fevers up to 40°C and acute pain in the left upper quadrant. Full blood count was normal and biochemical tests revealed increased serum globulin. Abdominal ultrasound revealed hepatomegaly and splenomegaly with multiple enlarged lymph nodes in the ...

Last Updated: 16 Dec 2014

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Systematic review of biomarkers to monitor therapeutic response in leishmaniasis.
 

Author(s): Anke E Kip, Manica Balasegaram, Jos H Beijnen, Jan H M Schellens, Peter J de Vries, Thomas P C Dorlo

Journal: Antimicrob. Agents Chemother.. 2015 Jan;59(1):1-14.

 

Recently, there has been a renewed interest in the development of new drugs for the treatment of leishmaniasis. This has spurred the need for pharmacodynamic markers to monitor and compare therapies specifically for visceral leishmaniasis, in which the primary recrudescence of parasites ...

Last Updated: 24 Dec 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Low Antimonial Dosage in American Mucosal Leishmaniasis
 

Status: Recruiting

Condition Summary: Mucosal Leishmaniasis; Mucocutaneous Leishmaniasis

 

Last Updated: 17 Jun 2015

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Compassionate Use of Sodium Stibogluconate (Pentostam) for Cutaneous and Mucocutaneous New World Leishmaniasis
 

Status: Available

Condition Summary: Leishmaniasis, Cutaneous; Leishmaniasis, Mucocutaneous

 

Last Updated: 12 Dec 2014

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Last Updated: 20 Aug 2015

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