Leishmaniasis

Common Name(s)

Leishmaniasis

Leishmaniasis is a parasitic disease spread by the bite of infected sand flies. There are several different forms of leishmaniasis. The most common are cutaneous and visceral. The cutaneous type causes skin sores. The visceral type affects internal organs such as the spleen, liver and bone marrow. People with this form usually have fever, weight loss, and an enlarged spleen and liver. Visceral disease can be deadly without proper treatment. Leishmaniasis is found in parts of the Middle East, Central America, South American, Asia, Africa, and southern Europe. Most of these countries are in the tropics and subtropics. It is possible but very unlikely to get this disease in the United States.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leishmaniasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leishmaniasis" returned 2278 free, full-text research articles on human participants. First 3 results:

[Leg ulcer revealing cutaneous leishmaniasis].
 

Author(s): Elalouani Elmehdi, Bachar Zerkly

Journal:

 

Leishmaniases are parasitic diseases occurring in endemic tropical and subtropical areas and caused by protozoa of the genus leishmania, transmitted by a diptera (sand fly). We here report a case of topical cutaneous leishmaniasis discovered in a 15-year old boy with painless ulcer ...

Last Updated: 31 Dec 1969

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[Assessment of a supervision grid being used in the laboratories of cutaneous leishmaniasis in Morocco].
 

Author(s): Bouchra El Mansouri, Fatima Amarir, Yamina Hajli, Hajiba Fellah, Faiza Sebti, Bouchra Delouane, Abderrahim Sadak, El Bachir Adlaoui, Mohammed Rhajaoui

Journal:

 

The aim of our study was to assess a standardized supervisory grid as a new supervision tool being used in the laboratories of leishmaniasis.

Last Updated: 31 Dec 1969

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Pre-clinical antigenicity studies of an innovative multivalent vaccine for human visceral leishmaniasis.
 

Author(s): Pedro Cecílio, Begoña Pérez-Cabezas, Laura Fernández, Javier Moreno, Eugenia Carrillo, José M Requena, Epifanio Fichera, Steven G Reed, Rhea N Coler, Shaden Kamhawi, Fabiano Oliveira, Jesus G Valenzuela, Luigi Gradoni, Reinhard Glueck, Gaurav Gupta, Anabela Cordeiro-da-Silva

Journal:

 

The notion that previous infection by Leishmania spp. in endemic areas leads to robust anti-Leishmania immunity, supports vaccination as a potentially effective approach to prevent disease development. Nevertheless, to date there is no vaccine available for human leishmaniasis. We ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leishmaniasis" returned 249 free, full-text review articles on human participants. First 3 results:

Post-kala-azar dermal leishmaniasis in the Indian subcontinent: A threat to the South-East Asia Region Kala-azar Elimination Programme.
 

Author(s): Eduard E Zijlstra, Fabiana Alves, Suman Rijal, Byron Arana, Jorge Alvar

Journal:

 

The South-East Asia Region Kala-azar Elimination Programme (KAEP) is expected to enter the consolidation phase in 2017, which focuses on case detection, vector control, and identifying potential sources of infection. Post-kala-azar dermal leishmaniasis (PKDL) is thought to play a ...

Last Updated: 31 Dec 1969

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Cytotoxic activity in cutaneous leishmaniasis.
 

Author(s): Taís M Campos, Rúbia Costa, Sara Passos, Lucas P Carvalho

Journal: Mem. Inst. Oswaldo Cruz. 2017 Nov;112(11):733-740.

 

Cutaneous leishmaniasis (CL) is a chronic disease caused by species of the protozoan Leishmania and characterised by the presence of ulcerated skin lesions. Both parasite and host factors affect the clinical presentation of the disease. The development of skin ulcers in CL is associated ...

Last Updated: 31 Dec 1969

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Combining epidemiology with basic biology of sand flies, parasites, and hosts to inform leishmaniasis transmission dynamics and control.
 

Author(s): Orin Courtenay, Nathan C Peters, Matthew E Rogers, Caryn Bern

Journal:

 

Quantitation of the nonlinear heterogeneities in Leishmania parasites, sand fly vectors, and mammalian host relationships provides insights to better understand leishmanial transmission epidemiology towards improving its control. The parasite manipulates the sand fly via production ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Predicting Visceral Leishmaniasis in HIV Infected Patients
 

Status: Recruiting

Condition Summary: Leishmaniasis, Visceral

 

Last Updated: 24 Oct 2017

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Last Updated: 11 Nov 2017

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Dedicated QT Study in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous Leishmaniasis
 

Status: Recruiting

Condition Summary: Mucocutaneous Leishmaniasis

 

Last Updated: 28 Feb 2017

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