Leishmaniasis

Common Name(s)

Leishmaniasis

Leishmaniasis is a parasitic disease spread by the bite of infected sand flies. There are several different forms of leishmaniasis. The most common are cutaneous and visceral. The cutaneous type causes skin sores. The visceral type affects internal organs such as the spleen, liver and bone marrow. People with this form usually have fever, weight loss, and an enlarged spleen and liver. Visceral disease can be deadly without proper treatment. Leishmaniasis is found in parts of the Middle East, Central America, South American, Asia, Africa, and southern Europe. Most of these countries are in the tropics and subtropics. It is possible but very unlikely to get this disease in the United States.
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leishmaniasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leishmaniasis" returned 1921 free, full-text research articles on human participants. First 3 results:

Spatial distribution and cluster analysis of a leishmaniasis outbreak in the south-western Madrid region, Spain, September 2009 to April 2013.
 

Author(s): D Gomez-Barroso, Z Herrador, J V San Martin, A Gherasim, M Aguado, A Romero-Mate, L Molina, P Aparicio, A Benito

Journal:

 

Last Updated: 27 Feb 2015

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Amphotericin B formulations and other drugs for visceral leishmaniasis.
 

Author(s): Jonathan Berman

Journal: Am. J. Trop. Med. Hyg.. 2015 Mar;92(3):471-3.

 

Last Updated: 5 Mar 2015

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Role of CD8(+) T cells in protection against Leishmania donovani infection in healed Visceral Leishmaniasis individuals.
 

Author(s): Himanshu Kaushal, Rachel Bras-Gonçalves, Narender Singh Negi, Jean-Loup Lemesre, Gérard Papierok, Poonam Salotra

Journal:

 

Majority of individuals with history of visceral leishmaniasis (VL) exhibit strong immunity to re-infection, however, the mechanism of resistance is poorly understood. It is unclear whether CD8(+) T cells contribute to protection against Leishmania donovani infection through cytotoxic ...

Last Updated: 8 Dec 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leishmaniasis" returned 172 free, full-text review articles on human participants. First 3 results:

Low quality evidence of epidemiological observational studies on leishmaniasis in Brazil.
 

Author(s): Bruno Trentini, Mário Steindel, Mariel A Marlow

Journal:

 

Brazil has implemented systematic control methods for leishmaniasis for the past 30 years, despite an increase in cases and continued spread of the disease to new regions. A lack high quality evidence from epidemiological observational studies impedes the development of novel control ...

Last Updated: 9 Sep 2014

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Complementary exams in the diagnosis of American tegumentary leishmaniasis.
 

Author(s): Ciro Martins Gomes, Natália Aparecida de Paula, Orlando Oliveira de Morais, Killarney Ataíde Soares, Ana Maria Roselino, Raimunda Nonata Ribeiro Sampaio

Journal: An Bras Dermatol. ;89(5):701-9.

 

The diagnosis of American Tegumentary Leishmaniasis is a difficult but essential task when considering the high toxicity profile of the drugs available. Since the discovery of its etiologic agent, numerous diagnostic tests have been developed. None of the tests available today can ...

Last Updated: 4 Sep 2014

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Diagnosis of leishmaniasis.
 

Author(s): Ehab Kotb Elmahallawy, Antonio Sampedro Martinez, Javier Rodriguez-Granger, Yannick Hoyos-Mallecot, Ahamd Agil, Jose Mari Navarro Mari, Jose Gutierrez Fernandez

Journal:

 

Leishmaniasis is a clinically heterogeneous syndrome caused by intracellular protozoan parasites of the genus Leishmania. The clinical spectrum of leishmaniasis encompasses subclinical (not apparent), localized (skin lesion), and disseminated (cutaneous, mucocutaneous, and visceral) ...

Last Updated: 13 Aug 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Clinical Trial of Miltefosine to Treat Mucosal Leishmaniasis
 

Status: Recruiting

Condition Summary: Leishmaniasis; Leishmaniasis, Mucocutaneous

 

Last Updated: 20 Jun 2011

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Low Antimonial Dosage in American Mucosal Leishmaniasis
 

Status: Recruiting

Condition Summary: Mucosal Leishmaniasis; Mucocutaneous Leishmaniasis

 

Last Updated: 26 Mar 2012

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Compassionate Use of Sodium Stibogluconate (Pentostam) for Cutaneous and Mucocutaneous New World Leishmaniasis
 

Status: Available

Condition Summary: Leishmaniasis, Cutaneous; Leishmaniasis, Mucocutaneous

 

Last Updated: 12 Dec 2014

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