Leishmaniasis

Common Name(s)

Leishmaniasis

Leishmaniasis is a parasitic disease spread by the bite of infected sand flies. There are several different forms of leishmaniasis. The most common are cutaneous and visceral. The cutaneous type causes skin sores. The visceral type affects internal organs such as the spleen, liver and bone marrow. People with this form usually have fever, weight loss, and an enlarged spleen and liver. Visceral disease can be deadly without proper treatment. Leishmaniasis is found in parts of the Middle East, Central America, South American, Asia, Africa, and southern Europe. Most of these countries are in the tropics and subtropics. It is possible but very unlikely to get this disease in the United States.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leishmaniasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leishmaniasis" returned 2178 free, full-text research articles on human participants. First 3 results:

Disease severity in patients with visceral leishmaniasis is not altered by co-infection with intestinal parasites.
 

Author(s): Fitsumbrhan Tajebe, Mulusew Getahun, Emebet Adem, Asrat Hailu, Mulualem Lemma, Helina Fikre, John Raynes, Aschalew Tamiru, Zemenay Mulugeta, Ermias Diro, Frederic Toulza, Ziv Shkedy, Tadesse Ayele, Manuel Modolell, Markus Munder, Ingrid Müller, Yegnasew Takele, Pascale Kropf

Journal:

 

Visceral leishmaniasis (VL) is a neglected tropical disease that affects the poorest communities and can cause substantial morbidity and mortality. Visceral leishmaniasis is characterized by the presence of Leishmania parasites in the spleen, liver and bone marrow, hepatosplenomegaly, ...

Last Updated: 21 Jul 2017

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A novel non-invasive diagnostic sampling technique for cutaneous leishmaniasis.
 

Author(s): Yasaman Taslimi, Pardis Sadeghipour, Sima Habibzadeh, Vahid Mashayekhi, Hossien Mortazavi, Ingrid Müller, Majella E Lane, Pascale Kropf, Sima Rafati

Journal:

 

Accurate diagnosis of cutaneous leishmaniasis (CL) is important for chemotherapy and epidemiological studies. Common approaches for Leishmania detection involve the invasive collection of specimens for direct identification of amastigotes by microscopy and the culturing of promastigotes ...

Last Updated: 13 Jul 2017

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Clinical and parasitological factors in parasite persistence after treatment and clinical cure of cutaneous leishmaniasis.
 

Author(s): Alvaro J Martínez-Valencia, Carlos Frisherald Daza-Rivera, Mariana Rosales-Chilama, Alexandra Cossio, Elkin J Casadiego Rincón, Mayur M Desai, Nancy Gore Saravia, María Adelaida Gómez

Journal:

 

The determinants of parasite persistence or elimination after treatment and clinical resolution of cutaneous leishmaniasis (CL) are unknown. We investigated clinical and parasitological parameters associated with the presence and viability of Leishmania after treatment and resolution ...

Last Updated: 13 Jul 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leishmaniasis" returned 228 free, full-text review articles on human participants. First 3 results:

Visceral leishmaniasis in Somalia: A review of epidemiology and access to care.
 

Author(s): Temmy Sunyoto, Julien Potet, Marleen Boelaert

Journal:

 

Somalia, ravaged by conflict since 1991, has areas endemic for visceral leishmaniasis (VL), a deadly parasitic disease affecting the rural poor, internally displaced, and pastoralists. Very little is known about VL burden in Somalia, where the protracted crisis hampers access to health ...

Last Updated: 9 Mar 2017

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The history of leishmaniasis.
 

Author(s): Dietmar Steverding

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In this review article the history of leishmaniasis is discussed regarding the origin of the genus Leishmania in the Mesozoic era and its subsequent geographical distribution, initial evidence of the disease in ancient times, first accounts of the infection in the Middle Ages, and ...

Last Updated: 16 Feb 2017

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Lip leishmaniasis: a case series with molecular identification and literature review.
 

Author(s): Iraj Mohammadpour, Mohammad Hossein Motazedian, Farhad Handjani, Gholam Reza Hatam

Journal:

 

Mucocutaneous leishmaniasis (MCL), a protozoan infectious disease, is very rare in Iran despite the endemicity of both cutaneous and visceral forms. It is transmitted by the Phlebotomus sand fly. The lip is considered one of the extraordinary sites. Lesions usually initiate with erythematous ...

Last Updated: 26 Jan 2017

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Predicting Visceral Leishmaniasis in HIV Infected Patients
 

Status: Not yet recruiting

Condition Summary: Leishmaniasis, Visceral

 

Last Updated: 17 May 2017

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Last Updated: 22 May 2016

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Dedicated QT Study in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous Leishmaniasis
 

Status: Recruiting

Condition Summary: Mucocutaneous Leishmaniasis

 

Last Updated: 28 Feb 2017

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