Leishmaniasis

Common Name(s)

Leishmaniasis

Leishmaniasis is a parasitic disease spread by the bite of infected sand flies. There are several different forms of leishmaniasis. The most common are cutaneous and visceral. The cutaneous type causes skin sores. The visceral type affects internal organs such as the spleen, liver and bone marrow. People with this form usually have fever, weight loss, and an enlarged spleen and liver. Visceral disease can be deadly without proper treatment. Leishmaniasis is found in parts of the Middle East, Central America, South American, Asia, Africa, and southern Europe. Most of these countries are in the tropics and subtropics. It is possible but very unlikely to get this disease in the United States.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leishmaniasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leishmaniasis" returned 2286 free, full-text research articles on human participants. First 3 results:

Leishmaniasis in high-burden countries: an epidemiological update based on data reported in 2014.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2016 Jun;91(22):287-96.

 

Last Updated: 3 Jun 2016

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[Determination of Leishmania species by PCR-RFLP in the smear samples taken from the lesions of cutaneous leishmaniasis cases].
 

Author(s): Hatice Ertabaklar, Sema Ertuğ, Serçin Özlem Çalışkan, Bülent Bozdoğan

Journal: Mikrobiyol Bul. 2016 Apr;50(2):300-6.

 

The forms of the disease caused by Leishmania species in Turkey as well as in Aegean region are cutaneous and visceral leishmaniasis (CL and VL, respectively), and the agent of CL is commonly L.tropica. However, L.infantum was also reported as being CL agent recently. Direct microscopic ...

Last Updated: 14 May 2016

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VISCERAL LEISHMANIASIS IN PETROLINA, STATE OFPERNAMBUCO, BRAZIL, 2007-2013.
 

Author(s): Andreina de Carvalho Araujo, Nara Nagle Vieira Matos Gonçalves, Filipe Dantas-Torres, Fernando Ferreira, Mauricio Claudio Horta

Journal: Rev. Inst. Med. Trop. Sao Paulo. 2016 ;58():29.

 

Visceral leishmaniasis is a life-threatening disease of great public health relevance in Brazil. The municipality of Petrolina is an endemic area in the State of Pernambuco, Brazil. This study was designed to assess the recent expansion of VL in the municipality of Petrolina, Pernambuco. ...

Last Updated: 14 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leishmaniasis" returned 213 free, full-text review articles on human participants. First 3 results:

Treatment of Cutaneous Leishmaniasis Caused by Leishmania aethiopica: A Systematic Review.
 

Author(s): Johan van Griensven, Endalamaw Gadisa, Abraham Aseffa, Asrat Hailu, Abate Mulugeta Beshah, Ermias Diro

Journal:

 

Leishmania aethiopica is the etiological agent of cutaneous leishmaniasis (CL) in Ethiopia and can cause severe and complicated cases such as diffuse CL (DCL), mucocutaneous leishmaniasis or extensive CL, requiring systemic treatment. Despite the substantial burden, evidence-based ...

Last Updated: 4 Mar 2016

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The Cure Rate after Placebo or No Therapy in American Cutaneous Leishmaniasis: A Systematic Review and Meta-Analysis.
 

Author(s): Gláucia Fernandes Cota, Marcos Roberto de Sousa, Tatiani Oliveira Fereguetti, Priscila Said Saleme, Thais Kawagoe Alvarisa, Ana Rabello

Journal:

 

There are few drugs with proven efficacy in cutaneous leishmaniasis (CL), and pentavalent antimonial derivatives are still the main first-line therapeutic agents worldwide, despite their recognized high toxicities. Randomized controlled clinical trials assessing the efficacy and safety ...

Last Updated: 20 Feb 2016

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Post-kala-azar dermal leishmaniasis and leprosy: case report and literature review.
 

Author(s): Maria Angela Bianconcini Trindade, Lana Luiza da Cruz Silva, Lucia Maria Almeida Braz, Valdir Sabbaga Amato, Bernard Naafs, Mirian Nacagami Sotto

Journal:

 

Post-kala-azar dermal leishmaniasis (PKDL) is a dermal complication of visceral leishmaniasis (VL), which may occur after or during treatment. It has been frequently reported from India and the Sudan, but its occurrence in South America has been rarely reported. It may mimic leprosy ...

Last Updated: 23 Nov 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Low Antimonial Dosage in American Mucosal Leishmaniasis
 

Status: Recruiting

Condition Summary: Mucosal Leishmaniasis; Mucocutaneous Leishmaniasis

 

Last Updated: 30 May 2016

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Compassionate Use of Sodium Stibogluconate (Pentostam) for Cutaneous and Mucocutaneous New World Leishmaniasis
 

Status: Available

Condition Summary: Leishmaniasis, Cutaneous; Leishmaniasis, Mucocutaneous

 

Last Updated: 12 Dec 2014

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Last Updated: 22 May 2016

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