Leishmaniasis

Common Name(s)

Leishmaniasis

Leishmaniasis is a parasitic disease spread by the bite of infected sand flies. There are several different forms of leishmaniasis. The most common are cutaneous and visceral. The cutaneous type causes skin sores. The visceral type affects internal organs such as the spleen, liver and bone marrow. People with this form usually have fever, weight loss, and an enlarged spleen and liver. Visceral disease can be deadly without proper treatment. Leishmaniasis is found in parts of the Middle East, Central America, South American, Asia, Africa, and southern Europe. Most of these countries are in the tropics and subtropics. It is possible but very unlikely to get this disease in the United States.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leishmaniasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leishmaniasis" returned 1780 free, full-text research articles on human participants. First 3 results:

Topical paromomycin and gentamicin for new world cutaneous leishmaniasis in Panama.
 

Author(s): Begoña Monge-Maillo, Rogelio López-Vélez

Journal: Am. J. Trop. Med. Hyg.. 2014 Jun;90(6):1191.

 

Last Updated: 6 Jun 2014

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Cytokine profiles amongst Sudanese patients with visceral leishmaniasis and malaria co-infections.
 

Author(s): Erika van den Bogaart, Al-Badawi A Talha, Masja Straetemans, Pètra F Mens, Emily R Adams, Martin P Grobusch, Bakri Y M Nour, Henk D F H Schallig

Journal:

 

The immune system plays a critical role in the development of co-infections, promoting or preventing establishment of multiple infections and shaping the outcome of pathogen-host interactions. Its ability to mediate the interplay between visceral leishmaniasis (VL) and malaria has ...

Last Updated: 4 Jun 2014

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Expansion of visceral leishmaniasis in the State of Rio de Janeiro, Brazil: report of the first autochthonous case in the municipality of Volta Redonda and the difficulty of diagnosis.
 

Author(s): Luiz Henrique Conde Sangenis, Sebastião Roberto de Almeida Lima, Cíntia Xavier de Mello, Daniela Trindade Cardoso, Jurema Nunes Mello, Maria Cristina Carvalho do Espírito Santo, Walter Tavares

Journal: Rev. Inst. Med. Trop. Sao Paulo. ;56(3):271-4.

 

Visceral Leishmaniasis has been showing remarkable epidemiological changes in recent decades, with marked expansion and an emergence of cases in urban areas of the North, Southeast and Midwest regions of Brazil. The Kala-azar cases reported here, despite being very characteristic, ...

Last Updated: 2 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leishmaniasis" returned 151 free, full-text review articles on human participants. First 3 results:

Treatment of American tegumentary leishmaniasis in special populations: a summary of evidence.
 

Author(s): Juliana Saboia Fontenele e Silva, Tais Freire Galvao, Maurício Gomes Pereira, Marcus Tolentino Silva

Journal: Rev. Soc. Bras. Med. Trop.. ;46(6):669-77.

 

We aimed to assess and synthesize the information available in the literature regarding the treatment of American tegumentary leishmaniasis in special populations. We searched MEDLINE (via PubMed), EMBASE, LILACS, SciELO, Scopus, Cochrane Library and mRCT databases to identify clinical ...

Last Updated: 11 Mar 2014

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Post kala-azar dermal leishmaniasis: an unresolved mystery.
 

Author(s): Debanjan Mukhopadhyay, Jane E Dalton, Paul M Kaye, Mitali Chatterjee

Journal: Trends Parasitol.. 2014 Feb;30(2):65-74.

 

Post kala-azar dermal leishmaniasis (PKDL), a cutaneous sequela of visceral leishmaniasis (VL), develops in some patients alongside but more commonly after apparent cure from VL. In view of the pivotal role of PKDL patients in the transmission of VL, here we review clinical, epidemiological, ...

Last Updated: 31 Jan 2014

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Therapeutic options for visceral leishmaniasis.
 

Author(s): Begoña Monge-Maillo, Rogelio López-Vélez

Journal: Drugs. 2013 Nov;73(17):1863-88.

 

Visceral leishmaniasis (VL), also known as Kala-Azar, is a disseminated protozoal infection caused principally by Leishmania donovani and Leishmania infantum (known as Leishmania chagasi in South America). The therapeutic options for VL are diverse and depend on different factors, ...

Last Updated: 22 Nov 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Clinical Trial of Miltefosine to Treat Mucosal Leishmaniasis
 

Status: Recruiting

Condition Summary: Leishmaniasis; Leishmaniasis, Mucocutaneous

 

Last Updated: 20 Jun 2011

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Low Antimonial Dosage in American Mucosal Leishmaniasis
 

Status: Recruiting

Condition Summary: Mucosal Leishmaniasis; Mucocutaneous Leishmaniasis

 

Last Updated: 26 Mar 2012

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Miltefosine to Treat Mucocutaneous Leishmaniasis
 

Status: Recruiting

Condition Summary: Leishmaniasis, Mucocutaneous; Cutaneous Leishmaniasis

 

Last Updated: 18 Jan 2011

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