Leishmaniasis

Common Name(s)

Leishmaniasis

Leishmaniasis is a parasitic disease spread by the bite of infected sand flies. There are several different forms of leishmaniasis. The most common are cutaneous and visceral. The cutaneous type causes skin sores. The visceral type affects internal organs such as the spleen, liver and bone marrow. People with this form usually have fever, weight loss, and an enlarged spleen and liver. Visceral disease can be deadly without proper treatment. Leishmaniasis is found in parts of the Middle East, Central America, South American, Asia, Africa, and southern Europe. Most of these countries are in the tropics and subtropics. It is possible but very unlikely to get this disease in the United States.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leishmaniasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leishmaniasis" returned 1795 free, full-text research articles on human participants. First 3 results:

Resolution of cutaneous leishmaniasis after acute eczema due to intralesional meglumine antimoniate.
 

Author(s): Erica de Camargo Ferreira e Vasconcellos, Maria Inês Fernandes Pimentel, Cláudia Maria Valete-Rosalino, Maria de Fátima Madeira, Armando de Oliveira Schubach

Journal: Rev. Inst. Med. Trop. Sao Paulo. ;56(4):361-2.

 

We report a case of a 42 year-old female, who came to a leishmaniasis reference center in Rio de Janeiro, Brazil, presenting a cutaneous leishmaniasis lesion in the right forearm. Treatment with low-dose intramuscular meglumine antimoniate (MA) (5 mg Sb5+/kg/day) was initiated, with ...

Last Updated: 31 Jul 2014

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Factors associated to adherence to different treatment schemes with meglumine antimoniate in a clinical trial for cutaneous leishmaniasis.
 

Author(s): Madelon Novato Ribeiro, Maria Inês Fernandes Pimentel, Armando de Oliveira Schubach, Raquel de Vasconcellos Carvalhães de Oliveira, José Liporage Teixeira, Madson Pedro da Silva Leite, Monique Fonseca, Ginelza Peres Lima dos Santos, Mariza Matos Salgueiro, Erica de Camargo Ferreira e Vasconcellos, Marcelo Rosandiski Lyra, Mauricio Naoto Saheki, Claudia Maria Valete-Rosalino

Journal: Rev. Inst. Med. Trop. Sao Paulo. ;56(4):291-6.

 

The favorable outcome of the treatment of a disease is influenced by the adherence to therapy. Our objective was to assess factors associated with adherence to treatment of patients included in a clinical trial of equivalence between the standard and alternative treatment schemes ...

Last Updated: 31 Jul 2014

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Temporal, spatial and spatiotemporal analysis of the occurrence of visceral leishmaniasis in humans in the City of Birigui, State of São Paulo, from 1999 to 2012.
 

Author(s): Carolina Portugal Vieira, Agda Maria Oliveira, Lilian Aparecida Colebrusco Rodas, Margareth Regina Dibo, Marluci Monteiro Guirado, Francisco Chiaravalloti Neto

Journal: Rev. Soc. Bras. Med. Trop.. ;47(3):350-8.

 

In 1999, Birigui and Araçatuba were the first municipalities in the State of São Paulo to present autochthonous cases of visceral leishmaniasis in humans (VLH). The aim of this study was to describe the temporal, spatial and spatiotemporal behaviors of VLH in Birigui.

Last Updated: 31 Jul 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leishmaniasis" returned 151 free, full-text review articles on human participants. First 3 results:

Treatment of American tegumentary leishmaniasis in special populations: a summary of evidence.
 

Author(s): Juliana Saboia Fontenele e Silva, Tais Freire Galvao, Maurício Gomes Pereira, Marcus Tolentino Silva

Journal: Rev. Soc. Bras. Med. Trop.. ;46(6):669-77.

 

We aimed to assess and synthesize the information available in the literature regarding the treatment of American tegumentary leishmaniasis in special populations. We searched MEDLINE (via PubMed), EMBASE, LILACS, SciELO, Scopus, Cochrane Library and mRCT databases to identify clinical ...

Last Updated: 11 Mar 2014

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Post kala-azar dermal leishmaniasis: an unresolved mystery.
 

Author(s): Debanjan Mukhopadhyay, Jane E Dalton, Paul M Kaye, Mitali Chatterjee

Journal: Trends Parasitol.. 2014 Feb;30(2):65-74.

 

Post kala-azar dermal leishmaniasis (PKDL), a cutaneous sequela of visceral leishmaniasis (VL), develops in some patients alongside but more commonly after apparent cure from VL. In view of the pivotal role of PKDL patients in the transmission of VL, here we review clinical, epidemiological, ...

Last Updated: 31 Jan 2014

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Therapeutic options for visceral leishmaniasis.
 

Author(s): Begoña Monge-Maillo, Rogelio López-Vélez

Journal: Drugs. 2013 Nov;73(17):1863-88.

 

Visceral leishmaniasis (VL), also known as Kala-Azar, is a disseminated protozoal infection caused principally by Leishmania donovani and Leishmania infantum (known as Leishmania chagasi in South America). The therapeutic options for VL are diverse and depend on different factors, ...

Last Updated: 22 Nov 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Clinical Trial of Miltefosine to Treat Mucosal Leishmaniasis
 

Status: Recruiting

Condition Summary: Leishmaniasis; Leishmaniasis, Mucocutaneous

 

Last Updated: 20 Jun 2011

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Low Antimonial Dosage in American Mucosal Leishmaniasis
 

Status: Recruiting

Condition Summary: Mucosal Leishmaniasis; Mucocutaneous Leishmaniasis

 

Last Updated: 26 Mar 2012

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Miltefosine to Treat Mucocutaneous Leishmaniasis
 

Status: Recruiting

Condition Summary: Leishmaniasis, Mucocutaneous; Cutaneous Leishmaniasis

 

Last Updated: 18 Jan 2011

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