Leishmaniasis

Common Name(s)

Leishmaniasis

Leishmaniasis is a parasitic disease spread by the bite of infected sand flies. There are several different forms of leishmaniasis. The most common are cutaneous and visceral. The cutaneous type causes skin sores. The visceral type affects internal organs such as the spleen, liver and bone marrow. People with this form usually have fever, weight loss, and an enlarged spleen and liver. Visceral disease can be deadly without proper treatment. Leishmaniasis is found in parts of the Middle East, Central America, South American, Asia, Africa, and southern Europe. Most of these countries are in the tropics and subtropics. It is possible but very unlikely to get this disease in the United States.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leishmaniasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leishmaniasis" returned 2122 free, full-text research articles on human participants. First 3 results:

Development and comparative evaluation of two antigen detection tests for Visceral Leishmaniasis.
 

Author(s): Aarthy C Vallur, Yeung L Tutterrow, Raodoh Mohamath, Sowmya Pattabhi, Asrat Hailu, Asim O Abdoun, Abdalla E Ahmed, Maowia Mukhtar, Md Abdus Salam, Meirielly Lima Almeida, Roque P Almeida, Dinesh Mondal, Audrey Albertini, Hashim Ghalib, Malcolm S Duthie, Steven G Reed

Journal:

 

Visceral leishmaniasis (VL) can be fatal without timely diagnosis and treatment. Treatment efficacies vary due to drug resistance, drug toxicity and co-morbidities. It is important to monitor treatment responsiveness to confirm cure and curtail relapse. Currently, microscopy of spleen, ...

Last Updated: 23 Sep 2015

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Post-kala-azar dermal Leishmaniasis in two different clinical contexts.
 

Author(s): Daniel Holanda Barroso, Claúdia Elise Ferraz Silva, Ana Carolina Depes Perdigao e Vasconcelos, Silvana Maria de Morais Cavalcanti, Maria Edileuza Felinto de Brito, Angela Cristina Rapela Medeiros

Journal: An Bras Dermatol. ;90(3 Suppl 1):108-10.

 

In Brazil, visceral Leishmaniasis is caused by Leishmania chagasi. The development of cutaneous lesions in visceral leishmaniasis patients has been described in two different clinical contexts. Patients with compromised immunity can develop skin lesions as a direct consequence of ...

Last Updated: 28 Aug 2015

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GENOTYPE CHARACTERIZATION OF Leishmania (Viannia) braziliensis ISOLATED FROM HUMAN AND CANINE BIOPSIES WITH AMERICAN CUTANEOUS LEISHMANIASIS.
 

Author(s): Lasaro Teixeira Ferreira, Aparecida Helena de Souza Gomes, Vera Lucia Pereira-Chioccola

Journal: Rev. Inst. Med. Trop. Sao Paulo. ;57(3):257-62.

 

American tegumentary leishmaniasis (ATL) can be caused by Leishmania (Viannia) braziliensis complex. The evolution of ATL initially results in lesions and can develop into disseminated or diffuse forms. The genetic diversity of L. (V.) braziliensis in some endemic areas of Brazil ...

Last Updated: 23 Jul 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leishmaniasis" returned 189 free, full-text review articles on human participants. First 3 results:

Theranostic applications of phage display to control leishmaniasis: selection of biomarkers for serodiagnostics, vaccination, and immunotherapy.
 

Author(s): Eduardo Antonio Ferraz Coelho, Miguel Angel Chávez-Fumagalli, Lourena Emanuele Costa, Carlos Alberto Pereira Tavares, Manuel Soto, Luiz Ricardo Goulart

Journal: Rev. Soc. Bras. Med. Trop.. ;48(4):370-9.

 

Phage display is a high-throughput subtractive proteomic technology used for the generation and screening of large peptide and antibody libraries. It is based on the selection of phage-fused surface-exposed peptides that recognize specific ligands and demonstrate desired functionality ...

Last Updated: 28 Aug 2015

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New delivery systems for amphotericin B applied to the improvement of leishmaniasis treatment.
 

Author(s): Miguel Angel Chávez-Fumagalli, Tatiana Gomes Ribeiro, Rachel Oliveira Castilho, Simone Odília Antunes Fernandes, Valbert Nascimento Cardoso, Cecília Steinberg Perilo Coelho, Débora Vasconcelos Costa Mendonça, Manuel Soto, Carlos Alberto Pereira Tavares, André Augusto Gomes Faraco, Eduardo Antonio Ferraz Coelho

Journal: Rev. Soc. Bras. Med. Trop.. ;48(3):235-42.

 

Leishmaniasis is one of the six major tropical diseases targeted by the World Health Organization. It is a life-threatening disease of medical, social and economic importance in endemic areas. No vaccine is yet available for human use, and chemotherapy presents several problems. Pentavalent ...

Last Updated: 25 Jun 2015

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Tegumentary leishmaniasis in the State of Amazonas: what have we learned and what do we need?
 

Author(s): Jorge Augusto de Oliveira Guerra, Marcel Gonçalves Maciel, Marcus Vinítius de Farias Guerra, Anette Chursciack Talhari, Suzane Ribeiro Prestes, Marcos Antonio Fernandes, Alda Maria Da-Cruz, Alessandra Martins, Leíla Ines de Aguiar Raposo Camara Coelho, Gustavo Adolfo Sierra Romero, Maria das Graças Vale Barbosa

Journal: Rev. Soc. Bras. Med. Trop.. 2015 ;48 Suppl 1():12-9.

 

This study evaluated the occurrence of American tegumentary leishmaniasis (ATL) in the State of Amazonas, Brazil, in the last 30 years with emphasis on the last 10 years (2001 to 2010). The disease was predominantly observed in males (76.2%), in the 21- to 30-year-old age group (26.6%) ...

Last Updated: 11 Jun 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Low Antimonial Dosage in American Mucosal Leishmaniasis
 

Status: Recruiting

Condition Summary: Mucosal Leishmaniasis; Mucocutaneous Leishmaniasis

 

Last Updated: 17 Jun 2015

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Compassionate Use of Sodium Stibogluconate (Pentostam) for Cutaneous and Mucocutaneous New World Leishmaniasis
 

Status: Available

Condition Summary: Leishmaniasis, Cutaneous; Leishmaniasis, Mucocutaneous

 

Last Updated: 12 Dec 2014

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Last Updated: 20 Aug 2015

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