Leiomyosarcoma

Common Name(s)

Leiomyosarcoma

Leiomyosarcoma is a rare cancerous tumor that consists of smooth (involuntary) muscle cells. Leiomyosarcoma is a type of sarcoma. It spreads through the blood stream and can affect the lungs, liver, blood vessels, or any other soft tissue in the body.  It is most often found in the uterus or abdomen.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leiomyosarcoma" for support, advocacy or research.

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leiomyosarcoma" for support, advocacy or research.

Logo
Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leiomyosarcoma" returned 327 free, full-text research articles on human participants. First 3 results:

CA125 expression in the tissue of uterine leiomyosarcoma.
 

Author(s): Joseph Menczer, Letizia Schreiber, Esther Berger, Erez Ben-Shem, Abraham Golan, Tally Levy

Journal: Isr. Med. Assoc. J.. 2014 Nov;16(11):697-9.

 

Background: Elevated serum levels of the epithelial marker CA125 are occasionally observed in leiomyosarcoma (LMS) patients.

Last Updated: 6 Jan 2015

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Favorable control of rapidly progressive retroperitoneal pleomorphic leiomyosarcoma with multimodality therapy: a case report.
 

Author(s): Kosuke Sagara, Kotoe Takayoshi, Eiji Kusumoto, Keita Uchino, Taisei Matsumura, Hitoshi Kusaba, Seiya Momosaki, Koji Ikejiri, Eishi Baba

Journal:

 

Retroperitoneal sarcomas (RPS), such as pleomorphic leiomyosarcoma, often invade or displace vital organs in the abdominal cavity and exhibit an aggressive clinical course. Complete surgical resection of the tumor and preoperative radiotherapy and chemotherapies can be used for non-metastatic ...

Last Updated: 3 Jul 2014

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Adult primary paratesticular mesenchymal tumors with emphasis on a case presentation and discussion of spermatic cord leiomyosarcoma.
 

Author(s): Andrea B Galosi, Marina Scarpelli, Roberta Mazzucchelli, Antonio Lopez-Beltran, Lucio Giustini, Liang Cheng, Rodolfo Montironi

Journal:

 

The aim of this report is related to adult primary paratesticular mesenchymal tumors with emphasis on a case presentation and discussion of the spermatic cord leiomyosarcoma. Primary paratesticular tumors are rare, only accounting for 7% to 10% of all intrascrotal tumors. In adults, ...

Last Updated: 4 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leiomyosarcoma" returned 41 free, full-text review articles on human participants. First 3 results:

Clinical characteristics and prognosis of primary leiomyosarcoma of the pancreas: a systematic review.
 

Author(s): Jianwei Xu, Taiping Zhang, Tianxiao Wang, Lei You, Yupei Zhao

Journal:

 

Primary pancreatic leiomyosarcoma (PLMS) is rare. The clinical characteristics and prognosis is still not completely understood. The aim of the present study is to identify the clinical characteristics and long-term outcomes of PLMS from the existing reported cases in different scientific ...

Last Updated: 16 Jan 2014

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Primary low grade intratesticular leiomyosarcoma: case report and review of the literature.
 

Author(s): Samir Abdullazade, Onder Kara, Bülent Akdoğan, Dilek Ertoy Baydar

Journal: Turk Patoloji Derg. 2013 ;29(3):227-30.

 

A 49-year-old male presented with a painful mass in the left scrotum. An inguinal orchiectomy was performed. Pathological examination revealed a well-differentiated leiomyosarcoma completely located inside the testicular parenchyma. We report this unusual case because primary leiomyosarcoma ...

Last Updated: 11 Sep 2013

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A case of rapidly progressing leiomyosarcoma combined with squamous cell carcinoma in the esophagus.
 

Author(s): Su Sun Jang, Woo Tae Kim, Bong Suk Ko, Eun Hae Kim, Jong Ok Kim, Kuhn Park, Seung Woo Lee

Journal: World J. Gastroenterol.. 2013 Aug;19(32):5385-8.

 

Esophageal leiomyosarcoma is a rare tumor that accounts for less than 1% of all malignant esophageal tumors. Esophageal leiomyosarcoma combined with squamous cell carcinoma is even rarer than solitary leiomyosarcoma. We experienced a case of leiomyosarcoma combined with squamous cell ...

Last Updated: 28 Aug 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Activity of Trabectedin or Gemcitabine + Docetaxel in Uterine Leiomyosarcoma
 

Status: Recruiting

Condition Summary: Leiomyosarcoma

 

Last Updated: 23 Sep 2014

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Last Updated: 19 Sep 2014

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