Leiomyosarcoma

Common Name(s)

Leiomyosarcoma

Leiomyosarcoma is a rare cancerous tumor that consists of smooth (involuntary) muscle cells. Leiomyosarcoma is a type of sarcoma. It spreads through the blood stream and can affect the lungs, liver, blood vessels, or any other soft tissue in the body.  It is most often found in the uterus or abdomen.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leiomyosarcoma" for support, advocacy or research.

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leiomyosarcoma" for support, advocacy or research.

Logo
Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leiomyosarcoma" returned 342 free, full-text research articles on human participants. First 3 results:

CA125 expression in the tissue of uterine leiomyosarcoma.
 

Author(s): Joseph Menczer, Letizia Schreiber, Esther Berger, Erez Ben-Shem, Abraham Golan, Tally Levy

Journal: Isr. Med. Assoc. J.. 2014 Nov;16(11):697-9.

 

Background: Elevated serum levels of the epithelial marker CA125 are occasionally observed in leiomyosarcoma (LMS) patients.

Last Updated: 6 Jan 2015

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Primary leiomyosarcoma of a horseshoe kidney in a woman with Turner syndrome: a case report.
 

Author(s): Toshikazu Tanaka, Takuya Koie, Ikuya Iwabuchi, Masaru Ogasawara, Toshiaki Kawaguchi, Chikara Ohyama

Journal:

 

Turner syndrome is characterized by complete or partial X-chromosome monosomy and has various clinical features, including horseshoe kidney. Leiomyosarcoma is an extremely rare tumor that accounts for only 0.1% of all invasive renal tumors.

Last Updated: 8 Aug 2014

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Gastric leiomyosarcoma as a rare cause of gastric outlet obstruction and perforation: a case report.
 

Author(s): Elroy P Weledji, George Enoworock, Marcelin Ngowe Ngowe

Journal:

 

Gastrointestinal stromal tumours are the most common mesenchymal malignancies of the gastrointestinal (GI) tract and gastric leiomyosarcoma represent 1-3% of gastric malignancies.

Last Updated: 8 Aug 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leiomyosarcoma" returned 41 free, full-text review articles on human participants. First 3 results:

Clinical characteristics and prognosis of primary leiomyosarcoma of the pancreas: a systematic review.
 

Author(s): Jianwei Xu, Taiping Zhang, Tianxiao Wang, Lei You, Yupei Zhao

Journal:

 

Primary pancreatic leiomyosarcoma (PLMS) is rare. The clinical characteristics and prognosis is still not completely understood. The aim of the present study is to identify the clinical characteristics and long-term outcomes of PLMS from the existing reported cases in different scientific ...

Last Updated: 16 Jan 2014

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Primary low grade intratesticular leiomyosarcoma: case report and review of the literature.
 

Author(s): Samir Abdullazade, Onder Kara, Bülent Akdoğan, Dilek Ertoy Baydar

Journal: Turk Patoloji Derg. 2013 ;29(3):227-30.

 

A 49-year-old male presented with a painful mass in the left scrotum. An inguinal orchiectomy was performed. Pathological examination revealed a well-differentiated leiomyosarcoma completely located inside the testicular parenchyma. We report this unusual case because primary leiomyosarcoma ...

Last Updated: 11 Sep 2013

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A case of rapidly progressing leiomyosarcoma combined with squamous cell carcinoma in the esophagus.
 

Author(s): Su Sun Jang, Woo Tae Kim, Bong Suk Ko, Eun Hae Kim, Jong Ok Kim, Kuhn Park, Seung Woo Lee

Journal: World J. Gastroenterol.. 2013 Aug;19(32):5385-8.

 

Esophageal leiomyosarcoma is a rare tumor that accounts for less than 1% of all malignant esophageal tumors. Esophageal leiomyosarcoma combined with squamous cell carcinoma is even rarer than solitary leiomyosarcoma. We experienced a case of leiomyosarcoma combined with squamous cell ...

Last Updated: 28 Aug 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Activity of Trabectedin or Gemcitabine + Docetaxel in Uterine Leiomyosarcoma
 

Status: Recruiting

Condition Summary: Leiomyosarcoma

 

Last Updated: 21 Apr 2015

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Last Updated: 19 Sep 2014

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