Leiomyosarcoma

Common Name(s)

Leiomyosarcoma

Leiomyosarcoma is a rare cancerous tumor that consists of smooth (involuntary) muscle cells. Leiomyosarcoma is a type of sarcoma. It spreads through the blood stream and can affect the lungs, liver, blood vessels, or any other soft tissue in the body.  It is most often found in the uterus or abdomen.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leiomyosarcoma" for support, advocacy or research.

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leiomyosarcoma" for support, advocacy or research.

Logo
Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leiomyosarcoma" returned 518 free, full-text research articles on human participants. First 3 results:

Long-lasting activity of trabectedin in refractory uterine leiomyosarcoma: a case report.
 

Author(s): Alberto Bongiovanni, Nada Riva, Marianna Ricci, Laura Mercatali, Chiara Liverani, Federico La Manna, Alessandro De Vita, Davide Cavaliere, Federica Pieri, Devil Oboldi, Giorgio Maria Verdecchia, Dino Amadori, Toni Ibrahim

Journal:

 

Leiomyosarcoma (LMS) is an aggressive soft tissue sarcoma derived from smooth muscle cells typically of uterine, gastrointestinal or soft tissue origin. The prognosis for this tumor is poor, with survival rates among the lowest of all soft tissue sarcomas. Surgery is the best approach ...

Last Updated: 23 Dec 2015

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Commentary on "A Case of Paratesticular Leiomyosarcoma Successfully Treated with Orchiectomy and Chemotherapy".
 

Author(s): Edoardo Virgilio, Stefania Uccini, Paolo Marchetti, Paolo Mercantini

Journal: Cancer Res Treat. 2016 Jan;48(1):422-4.

 

Last Updated: 26 Jan 2016

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Clinical Observations and Molecular Variables of Primary Vascular Leiomyosarcoma.
 

Author(s): Christina L Roland, Genevieve M Boland, Elizabeth G Demicco, Kristelle Lusby, Davis Ingram, Caitlin D May, Christine M Kivlin, Kelsey Watson, Ghadah A Al Sannaa, Wei-Lien Wang, Vinod Ravi, Raphael E Pollock, Dina Lev, Janice N Cormier, Kelly K Hunt, Barry W Feig, Alexander J Lazar, Keila E Torres

Journal: JAMA Surg. 2016 Apr;151(4):347-54.

 

Vascular leiomyosarcomas are a rare subtype of leiomyosarcomas that most commonly affect the inferior vena cava and account for 5% of all leiomyosarcomas. These tumors are aggressive malignant tumors for which adjuvant modalities have not shown increased efficacy compared with surgery.

Last Updated: 21 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leiomyosarcoma" returned 58 free, full-text review articles on human participants. First 3 results:

[Leiomyosarcoma of the tongue: about a case].
 

Author(s): Lahcen El Jahd, Ismail Barhmi, Nabil Tazi, Sami Rouadi, Reda Abada, Mohammed Roubal, Abdelaziz Janah, Mohammed Mahtar

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Last Updated: 25 Nov 2015

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Clinical characteristics and prognosis of primary leiomyosarcoma of the pancreas: a systematic review.
 

Author(s): Jianwei Xu, Taiping Zhang, Tianxiao Wang, Lei You, Yupei Zhao

Journal:

 

Primary pancreatic leiomyosarcoma (PLMS) is rare. The clinical characteristics and prognosis is still not completely understood. The aim of the present study is to identify the clinical characteristics and long-term outcomes of PLMS from the existing reported cases in different scientific ...

Last Updated: 16 Jan 2014

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Primary low grade intratesticular leiomyosarcoma: case report and review of the literature.
 

Author(s): Samir Abdullazade, Onder Kara, Bülent Akdoğan, Dilek Ertoy Baydar

Journal: Turk Patoloji Derg. 2013 ;29(3):227-30.

 

A 49-year-old male presented with a painful mass in the left scrotum. An inguinal orchiectomy was performed. Pathological examination revealed a well-differentiated leiomyosarcoma completely located inside the testicular parenchyma. We report this unusual case because primary leiomyosarcoma ...

Last Updated: 11 Sep 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 2 Mar 2016

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Trial of Nilotinib and Adriamycin as Treatment in Liposarcomas and Leiomyosarcomas of Retroperitoneum
 

Status: Recruiting

Condition Summary: Retroperitoneal Liposarcoma; Retroperitoneal Leiomyosarcoma; Chondrosarcoma

 

Last Updated: 23 Oct 2015

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