Leiomyosarcoma

Common Name(s)

Leiomyosarcoma

Leiomyosarcoma is a rare cancerous tumor that consists of smooth (involuntary) muscle cells. Leiomyosarcoma is a type of sarcoma. It spreads through the blood stream and can affect the lungs, liver, blood vessels, or any other soft tissue in the body.  It is most often found in the uterus or abdomen.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leiomyosarcoma" for support, advocacy or research.

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leiomyosarcoma" for support, advocacy or research.

Logo
Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leiomyosarcoma" returned 542 free, full-text research articles on human participants. First 3 results:

Uterine epithelioid leiomyosarcoma with c-kit expression and YWHAE gene rearrangement: a case report of a diagnostic pitfall of uterine sarcoma.
 

Author(s): Terufumi Kubo, Shintaro Sugita, Ryuichi Wada, Noriaki Kikuchi, Masahiro Iwasaki, Yumika Ito, Taro Sugawara, Hiromi Fujita, Makoto Emori, Ryoichi Tanaka, Hiroshi Hirano, Tsuyoshi Saito, Tadashi Hasegawa

Journal:

 

Uterine sarcoma is a rare tumor that is often difficult to classify based on morphological and immunohistochemical analysis alone. Limited access to molecular biological analysis in routine practice would hinder making a definitive diagnosis.

Last Updated: 14 Mar 2017

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Inferior vena cava leiomyosarcoma: vascular reconstruction is not always mandatory.
 

Author(s): Maher Slimane, Nada Belhaj Yahia, Hanene Bouaziz, Hatem Bouzaine, Jamel Benhassouna, Tarek Ben Dhieb, Monia Hechiche, Amor Gammoudi, Khaled Rahal

Journal:

 

Leiomyosarcoma (LMS) of inferior vena cava is a rare and aggressive tumor, arising from the smooth muscle cells in the vessel wall. A large complete surgical resection is the essential treatment. The need of vascular reconstruction is not always mandatory. It's above all to understand ...

Last Updated: 3 Feb 2017

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A Rare Case of Colonic Leiomyosarcoma in Association with Ulcerative Colitis.
 

Author(s): Daisuke Akutsu, Yuji Mizokami, Hideo Suzuki, Masahiko Terasaki, Toshiaki Narasaka, Tsuyoshi Kaneko, Hirofumi Matsui, Tsuyoshi Enomoto, Taiki Sato, Ichinosuke Hyodo

Journal: Intern. Med.. ;55(19):2799-2803.

 

Ulcerative colitis (UC) is known to be associated with an increased risk of colorectal cancer. However, the occurrence of non-epithelial malignancies is uncommon. An elevated lesion in the descending colon was found in a 51-year-old woman with a 30-year history of UC. Despite tumor ...

Last Updated: 11 Oct 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leiomyosarcoma" returned 75 free, full-text review articles on human participants. First 3 results:

Primary leiomyosarcoma of the spine: A case report and literature review.
 

Author(s): Yi Yang, Litai Ma, Lingli Li, Hao Liu

Journal: Medicine (Baltimore). 2017 Mar;96(9):e6227.

 

Primary leiomyosarcoma of the bone was firstly reported by Evans and Sanerkin in 1965, whereas primary leiomyosarcoma of the vertebra is extremely rare. Because of the rarity of primary vertebral leiomyosarcoma, the diagnosis, treatment, and clinical outcome still remain controversial. ...

Last Updated: 1 Mar 2017

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Primary Leiomyosarcoma of the Pancreas-a Case Report and a Comprehensive Review.
 

Author(s): Jon Arne Søreide, Erling Sandøy Undersrud, Mohammed S S Al-Saiddi, Tore Tholfsen, Kjetil Søreide

Journal: J Gastrointest Cancer. 2016 Dec;47(4):358-365.

 

Primary mesenchymal tumors of the pancreas are rare, with leiomyosarcomas the most encountered entities among the pancreatic sarcomas. With few exceptions, single case reports published over the last six decades constitute the entire scientific literature on this topic. Thus, evidence ...

Last Updated: 17 Sep 2016

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Portal vein leiomyosarcoma: a case report and review of the literature.
 

Author(s): Antje E Gohrbandt, Torsten Hansen, Christian Ell, Stefan S Heinrich, Hauke Lang

Journal:

 

Leiomyosarcoma of vascular smooth muscle is a very rare entity. A fair number of cases of vascular leiomyosarcomas have been reported, and the vast majority of these tumors arose from the inferior vena cava.

Last Updated: 1 Sep 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 17 Mar 2017

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Study Comparing Efficacy of Doxorubicin With Trabectedin Followed by Trabectedin Versus Doxorubicine in Patients With Leiomyosarcoma
 

Status: Not yet recruiting

Condition Summary: Uterine or Soft Tissue Leiomyosarcoma

 

Last Updated: 6 Jan 2017

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