Leiomyosarcoma

Common Name(s)

Leiomyosarcoma

Leiomyosarcoma is a rare cancerous tumor that consists of smooth (involuntary) muscle cells. Leiomyosarcoma is a type of sarcoma. It spreads through the blood stream and can affect the lungs, liver, blood vessels, or any other soft tissue in the body.  It is most often found in the uterus or abdomen.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leiomyosarcoma" for support, advocacy or research.

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leiomyosarcoma" for support, advocacy or research.

Logo
Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leiomyosarcoma" returned 502 free, full-text research articles on human participants. First 3 results:

Long-term response to first-line trabectedin in an elderly female patient with a metastatic leiomyosarcoma unfit for anthracycline.
 

Author(s): Marco Maruzzo, Antonella Brunello, Alberto Diminutto, Marco Rastrelli, Umberto Basso

Journal: Anticancer Drugs. 2016 Mar;27(3):264-7.

 

Systemic chemotherapy comprising anthracycline monotherapy is the standard regimen for metastatic soft tissue sarcomas, particularly leiomyosarcomas, which have limited sensitivity to ifosfamide. However, the optimal chemotherapy regimen for elderly patients, especially those considered ...

Last Updated: 30 Jan 2016

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Expression of Forkhead box M1 in soft tissue leiomyosarcoma: Clinicopathologic and in vitro study using a newly established cell line.
 

Author(s): Akira Maekawa, Kenichi Kohashi, Nokitaka Setsu, Masaaki Kuda, Kunio Iura, Takeaki Ishii, Tomoya Matsunobu, Tetsuya Nakatsura, Yukihide Iwamoto, Yoshinao Oda

Journal: Cancer Sci.. 2016 Jan;107(1):95-102.

 

Leiomyosarcoma (LMS) of soft tissue is a sarcoma with smooth-muscle differentiation, and conventional chemotherapy does not improve its outcome. The application of novel antitumor agents and precise prognostication has been demanded. The expression of the protein Forkhead box M1 (FOXM1), ...

Last Updated: 25 Jan 2016

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[Gastric leiomyosarcoma simulating splenic hilum tumor: report of a case].
 

Author(s): Mohamed Tarchouli, Ahmed Bounaim, Moulay Brahim Ratbi, Mohamed Said Belhamidi, Abdelhak Bensal, Badr Aitidir, Adil Boudhas, Abdelmounaim Ait Ali, Khalid Sair

Journal:

 

Last Updated: 3 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leiomyosarcoma" returned 55 free, full-text review articles on human participants. First 3 results:

[Leiomyosarcoma of the tongue: about a case].
 

Author(s): Lahcen El Jahd, Ismail Barhmi, Nabil Tazi, Sami Rouadi, Reda Abada, Mohammed Roubal, Abdelaziz Janah, Mohammed Mahtar

Journal:

 

Last Updated: 25 Nov 2015

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Clinical characteristics and prognosis of primary leiomyosarcoma of the pancreas: a systematic review.
 

Author(s): Jianwei Xu, Taiping Zhang, Tianxiao Wang, Lei You, Yupei Zhao

Journal:

 

Primary pancreatic leiomyosarcoma (PLMS) is rare. The clinical characteristics and prognosis is still not completely understood. The aim of the present study is to identify the clinical characteristics and long-term outcomes of PLMS from the existing reported cases in different scientific ...

Last Updated: 16 Jan 2014

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Primary low grade intratesticular leiomyosarcoma: case report and review of the literature.
 

Author(s): Samir Abdullazade, Onder Kara, Bülent Akdoğan, Dilek Ertoy Baydar

Journal: Turk Patoloji Derg. 2013 ;29(3):227-30.

 

A 49-year-old male presented with a painful mass in the left scrotum. An inguinal orchiectomy was performed. Pathological examination revealed a well-differentiated leiomyosarcoma completely located inside the testicular parenchyma. We report this unusual case because primary leiomyosarcoma ...

Last Updated: 11 Sep 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 2 Mar 2016

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Trial of Nilotinib and Adriamycin as Treatment in Liposarcomas and Leiomyosarcomas of Retroperitoneum
 

Status: Recruiting

Condition Summary: Retroperitoneal Liposarcoma; Retroperitoneal Leiomyosarcoma; Chondrosarcoma

 

Last Updated: 23 Oct 2015

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