Leiomyosarcoma

Common Name(s)

Leiomyosarcoma

Leiomyosarcoma is a rare cancerous tumor that consists of smooth (involuntary) muscle cells. Leiomyosarcoma is a type of sarcoma. It spreads through the blood stream and can affect the lungs, liver, blood vessels, or any other soft tissue in the body.  It is most often found in the uterus or abdomen.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leiomyosarcoma" for support, advocacy or research.

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leiomyosarcoma" for support, advocacy or research.

Logo
Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leiomyosarcoma" returned 521 free, full-text research articles on human participants. First 3 results:

Primary Pulmonary Valve Leiomyosarcoma in a 35-Year-Old Woman.
 

Author(s): Farveh Vakilian, Mahmoud M Shabestari, Hoorak Poorzand, Mohammad Abbasi Teshnizi, Abolghasem Allahyari, Bahram Memar

Journal:

 

Primary cardiac leiomyosarcomas are rare, with a high incidence of local recurrence. Herein, we report the case of a 35-year-old woman who was admitted with right ventricular failure and suspected pulmonary embolism. Upon echocardiography, we detected a mass in the pulmonary trunk ...

Last Updated: 6 Apr 2016

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PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcoma.
 

Author(s): Yael Babichev, Leah Kabaroff, Alessandro Datti, David Uehling, Methvin Isaac, Rima Al-Awar, Michael Prakesch, Ren X Sun, Paul C Boutros, Rosemarie Venier, Brendan C Dickson, Rebecca A Gladdy

Journal:

 

Leiomyosarcoma (LMS) is a common type of soft tissue sarcoma that responds poorly to standard chemotherapy. Thus the goal of this study was to identify novel selective therapies that may be effective in leiomyosarcoma by screening cell lines with a small molecule library comprised ...

Last Updated: 8 Mar 2016

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[Leiomyosarcoma of the bladder in a 64 year old patient].
 

Author(s): Mustapha Elkabous, Anwar Boukir, Asmaa Lakhdissi, Hamza Ettahiri, Fadila Kohen, Mohammed Afif, Youness Jabbour, Amal Drissy, Saber Boutayeb, Hassan Errihani

Journal:

 

Last Updated: 26 Feb 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leiomyosarcoma" returned 66 free, full-text review articles on human participants. First 3 results:

Portal vein leiomyosarcoma: a case report and review of the literature.
 

Author(s): Antje E Gohrbandt, Torsten Hansen, Christian Ell, Stefan S Heinrich, Hauke Lang

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Leiomyosarcoma of vascular smooth muscle is a very rare entity. A fair number of cases of vascular leiomyosarcomas have been reported, and the vast majority of these tumors arose from the inferior vena cava.

Last Updated: 1 Sep 2016

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Leiomyosarcoma of urinary bladder-potential mimicker of carcinoma: Case report and short review of literature.
 

Author(s): R Patnayak, A Jena, S Rambabu, M K Reddy

Journal: Indian J Cancer. ;52(4):573-4.

 

Last Updated: 10 Mar 2016

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A very rare case of a small bowel leiomyosarcoma leading to ileocaecal intussusception treated with a laparoscopic resection: a case report and a literature review.
 

Author(s): Tomasz Guzel, Katarzyna Mech, Michał Mazurkiewicz, Bohdan Dąbrowski, Gustaw Lech, Andrzej Chaber, Maciej Słodkowski

Journal:

 

Small bowel tumours are rare and comprise less than 2% of all primary gastrointestinal neoplasms. Among these tumours, a leiomyosarcoma belonging to soft tissue sarcomas is extremely rare and accounts for about 1 % of malignant mesenchymal lesions in the gastrointestinal tract. Due ...

Last Updated: 25 Feb 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 2 Mar 2016

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Study Comparing Efficacy of Doxorubicin With Trabectedin Followed by Trabectedin Versus Doxorubicine in Patients With Leiomyosarcoma
 

Status: Not yet recruiting

Condition Summary: Uterine or Soft Tissue Leiomyosarcoma

 

Last Updated: 6 Jan 2017

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