Leiomyosarcoma

Common Name(s)

Leiomyosarcoma

Leiomyosarcoma is a rare cancerous tumor that consists of smooth (involuntary) muscle cells. Leiomyosarcoma is a type of sarcoma. It spreads through the blood stream and can affect the lungs, liver, blood vessels, or any other soft tissue in the body.  It is most often found in the uterus or abdomen.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leiomyosarcoma" for support, advocacy or research.

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Leiomyosarcoma" for support, advocacy or research.

Logo
Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Leiomyosarcoma" returned 498 free, full-text research articles on human participants. First 3 results:

[Gastric leiomyosarcoma simulating splenic hilum tumor: report of a case].
 

Author(s): Mohamed Tarchouli, Ahmed Bounaim, Moulay Brahim Ratbi, Mohamed Said Belhamidi, Abdelhak Bensal, Badr Aitidir, Adil Boudhas, Abdelmounaim Ait Ali, Khalid Sair

Journal:

 

Last Updated: 3 Nov 2015

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Pyrosequencing-Based Assays for Rapid Detection of HER2 and HER3 Mutations in Clinical Samples Uncover an E332E Mutation Affecting HER3 in Retroperitoneal Leiomyosarcoma.
 

Author(s): Paula González-Alonso, Cristina Chamizo, Víctor Moreno, Juan Madoz-Gúrpide, Nerea Carvajal, Lina Daoud, Sandra Zazo, Ester Martín-Aparicio, Ion Cristóbal, Raúl Rincón, Jesús García-Foncillas, Federico Rojo

Journal:

 

Mutations in Human Epidermal Growth Factor Receptors (HER) are associated with poor prognosis of several types of solid tumors. Although HER-mutation detection methods are currently available, such as Next-Generation Sequencing (NGS), alternative pyrosequencing allow the rapid characterization ...

Last Updated: 20 Aug 2015

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Primary pulmonary leiomyosarcoma of lung: An unusual entity with brief review.
 

Author(s): Devajit Nath, Sudheer Arava, Prashant Joshi, Karan Madan, Sandeep Mathur

Journal: Indian J Pathol Microbiol. ;58(3):338-40.

 

Primary pulmonary leiomyosarcomas are rare and diagnostically challenging group of neoplasms approximately constituting 0.2-0.5% of all primary lung malignancies. They originate from the smooth muscle cells of the bronchial wall, blood vessels or from the pulmonary interstitium. Here ...

Last Updated: 15 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Leiomyosarcoma" returned 53 free, full-text review articles on human participants. First 3 results:

Clinical characteristics and prognosis of primary leiomyosarcoma of the pancreas: a systematic review.
 

Author(s): Jianwei Xu, Taiping Zhang, Tianxiao Wang, Lei You, Yupei Zhao

Journal:

 

Primary pancreatic leiomyosarcoma (PLMS) is rare. The clinical characteristics and prognosis is still not completely understood. The aim of the present study is to identify the clinical characteristics and long-term outcomes of PLMS from the existing reported cases in different scientific ...

Last Updated: 16 Jan 2014

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Primary low grade intratesticular leiomyosarcoma: case report and review of the literature.
 

Author(s): Samir Abdullazade, Onder Kara, Bülent Akdoğan, Dilek Ertoy Baydar

Journal: Turk Patoloji Derg. 2013 ;29(3):227-30.

 

A 49-year-old male presented with a painful mass in the left scrotum. An inguinal orchiectomy was performed. Pathological examination revealed a well-differentiated leiomyosarcoma completely located inside the testicular parenchyma. We report this unusual case because primary leiomyosarcoma ...

Last Updated: 11 Sep 2013

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A case of rapidly progressing leiomyosarcoma combined with squamous cell carcinoma in the esophagus.
 

Author(s): Su Sun Jang, Woo Tae Kim, Bong Suk Ko, Eun Hae Kim, Jong Ok Kim, Kuhn Park, Seung Woo Lee

Journal: World J. Gastroenterol.. 2013 Aug;19(32):5385-8.

 

Esophageal leiomyosarcoma is a rare tumor that accounts for less than 1% of all malignant esophageal tumors. Esophageal leiomyosarcoma combined with squamous cell carcinoma is even rarer than solitary leiomyosarcoma. We experienced a case of leiomyosarcoma combined with squamous cell ...

Last Updated: 28 Aug 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Activity of Trabectedin or Gemcitabine + Docetaxel in Uterine Leiomyosarcoma
 

Status: Recruiting

Condition Summary: Leiomyosarcoma

 

Last Updated: 21 Apr 2015

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Last Updated: 2 Mar 2016

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