Anal cancer

Common Name(s)

Anal cancer

Anal Cancer is a type of cancer that affects the anal canal. Cancer is uncontrolled cell growth due to genetic changes. Cancer cells can invade surrounding tissues. The anus is a passage that connects the rectum, the end of the large intestines, to the outside part of the body. Symptoms include anal/rectal bleeding, lumps around the anal opening, recurring anal pain, anal itching, change in bowel habits, narrowing of the stools, anal discharge, and swollen lymph nodes (glands) in the anal or groin areas. Twenty percent (20%) of anal cancer cases show no symptoms. Although anal cancer most commonly affects individuals over the age 55, it is possible for anal cancer to occur at younger ages. People who are diagnosed with HPV (see also human papilloma virus) have an increased risk of developing this cancer. Other risk factors include unprotected sex, anal sex, smoking, weakened immune systems, open anal wounds, and pelvic radiation. Treatment of anal cancers includes surgery, radiation therapy, and chemotherapy, all which are very effective in curing the cancer. Diagnosis is usually done through an anal canal examination, stool tests, or colonoscopies, and can usually be found during a yearly physical check-up. If you or a family member has been diagnosed with anal cancer, talk with your doctor to learn about the most up to date treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anal cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

Last Updated: 6 Nov 2012

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anal cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

View Details
Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

http://stupidcancer.org

Last Updated: 6 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anal cancer" returned 156 free, full-text research articles on human participants. First 3 results:

Reasons for delays in diagnosis of anal cancer and the effect on patient satisfaction.
 

Author(s): Sharon Chiu, Kurian Joseph, Sunita Ghosh, Rose-Marie Cornand, Dan Schiller

Journal: Can Fam Physician. 2015 Nov;61(11):e509-16.

 

To quantify the time to diagnosis of anal cancer after onset of symptoms, to identify reasons for delays in diagnosis, and to identify the effect of delays on patient satisfaction.

Last Updated: 17 Feb 2016

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Intensified intensity-modulated radiotherapy in anal cancer with prevalent HPV p16 positivity.
 

Author(s): Liliana Belgioia, Stefano Vagge, Dario Agnese, Stefania Garelli, Roberto Murialdo, Giuseppe Fornarini, Silvana Chiara, Fabio Gallo, Almalina Bacigalupo, Renzo Corvò

Journal: World J. Gastroenterol.. 2015 Oct;21(37):10688-96.

 

To investigate the toxicity and response of intensity-modulated radiotherapy schedule intensified with a simultaneous integrated boost in anal canal cancer.

Last Updated: 12 Oct 2015

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Modeling early haematologic adverse events in conformal and intensity-modulated pelvic radiotherapy in anal cancer.
 

Author(s): Maxwell Robinson, Ahmed Sabbagh, Rebecca Muirhead, Lisa Durrant, Frank Van den Heuvel, Maria Hawkins

Journal: Radiother Oncol. 2015 Nov;117(2):246-51.

 

To determine if there are differences between dose to pelvic bone marrow (PBM) using intensity modulated radiotherapy (IMRT) under UK guidance versus conformal radiotherapy (CRT) per ACT II protocol and if differences translate to rates of early haematological adverse events grade ...

Last Updated: 15 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anal cancer" returned 36 free, full-text review articles on human participants. First 3 results:

Screening to prevent anal cancer: Current thinking and future directions.
 

Author(s): Joel M Palefsky

Journal: Cancer Cytopathol. 2015 Sep;123(9):509-10.

 

Last Updated: 17 Sep 2015

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Screening for Anal Cancer in Women.
 

Author(s): Anna-Barbara Moscicki, Teresa M Darragh, J Michael Berry-Lawhorn, Jennifer M Roberts, Michelle J Khan, Lori A Boardman, Elizabeth Chiao, Mark H Einstein, Stephen E Goldstone, Naomi Jay, Wendy M Likes, Elizabeth A Stier, Mark L Welton, Dorothy J Wiley, Joel M Palefsky

Journal: J Low Genit Tract Dis. 2015 Jul;19(3 Suppl 1):S27-42.

 

The incidence of anal cancer is higher in women than men in the general population and has been increasing for several decades. Similar to cervical cancer, most anal cancers are associated with human papillomavirus (HPV), and it is believed that anal cancers are preceded by anal high-grade ...

Last Updated: 24 Jun 2015

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Anal cancer treatment: current status and future perspectives.
 

Author(s): Marwan Ghosn, Hampig Raphael Kourie, Pamela Abdayem, Joelle Antoun, Dolly Nasr

Journal: World J. Gastroenterol.. 2015 Feb;21(8):2294-302.

 

Anal cancers (AC) are relatively rare tumors. Their incidence is increasing, particularly among men who have sex with other men due to widespread infection by human papilloma virus. The majority of anal cancers are squamous cell carcinomas, and they are treated according to stage. ...

Last Updated: 5 Mar 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Shared Decision Making With Anal Cancer Patients on Radiation Dose
 

Status: Recruiting

Condition Summary: Anal Cancer

 

Last Updated: 27 May 2016

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Functional Outcomes Following Anal Cancer Treatment
 

Status: Not yet recruiting

Condition Summary: Anal Cancer

 

Last Updated: 13 May 2013

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Anal Cancer Radiotherapy Study
 

Status: Recruiting

Condition Summary: Anal Cancer

 

Last Updated: 4 Sep 2013

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