Legg-Calve-Perthes disease

Common Name(s)

Legg-Calve-Perthes disease, Coxa plana

Legg-Calve-Perthes disease occurs when the ball of the thighbone in the hip doesnÕt get enough blood, causing the bone to die. Early symptoms may include mildly painful limp, pain down the inner thigh to the knee, some restriction of hip movement, pain at extremes of movement, and tenderness over the hip joint. Treatment may include a brief period of bed rest (1 to 3 days) followed by bracing. Rarely bracing may be required for 2 to 3 years. Chance of recovery (prognosis) varies, but tends to be better for younger patients (e.g., less than 6 years of age). Some people with this syndrome go on to develop degenerative arthritis. The cause of the condition is unknown.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Legg-Calve-Perthes disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Legg-Calve-Perthes disease" returned 47 free, full-text research articles on human participants. First 3 results:

Legg-Calvé-Perthes disease in children with Down syndrome.
 

Author(s): Mehmet Ali Talmac, Muayad Kadhim, Kenneth J Rogers, Laurens Holmes, Freeman Miller

Journal: Acta Orthop Traumatol Turc. 2013 ;47(5):334-8.

 

The aim of this study was to describe the features of Perthes disease in patients with Down syndrome.

Last Updated: 29 Oct 2013

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Legg-Calve-Perthes disease in two generations of male family members: a case report.
 

Author(s): Ammar K Al-Omran, Mir Sadat-Ali

Journal: J Orthop Surg (Hong Kong). 2013 Aug;21(2):258-61.

 

Legg-Calve-Perthes disease (LCPD) is a type of avascular necrosis of the femoral head occurring mainly in male children and causing early osteoarthritis. We report 2 generations of 4 male family members with LCPD-like features and mutation of the COL2A1 gene of the 12q13 chromosome. ...

Last Updated: 9 Sep 2013

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Classifications in brief: the Herring lateral pillar classification for Legg-Calvé-Perthes disease.
 

Author(s): Kathleen M Kollitz, Albert O Gee

Journal: Clin. Orthop. Relat. Res.. 2013 Jul;471(7):2068-72.

 

Last Updated: 10 Jun 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Legg-Calve-Perthes disease" returned 5 free, full-text review articles on human participants. First 3 results:

Do femoral or salter innominate osteotomies improve femoral head sphericity in Legg-Calvé-Perthes disease? A meta-analysis.
 

Author(s): Neil Saran, Renjit Varghese, Kishore Mulpuri

Journal: Clin. Orthop. Relat. Res.. 2012 Sep;470(9):2383-93.

 

Recently, the authors of two prospective multicenter observational studies recommended surgery to improve head sphericity in older children, whereas large retrospective observational studies suggest that surgery does not improve head sphericity in older children. Thus, the treatment ...

Last Updated: 9 Aug 2012

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Evidence for using bisphosphonate to treat Legg-Calvé-Perthes disease.
 

Author(s): Megan L Young, David G Little, Harry K W Kim

Journal: Clin. Orthop. Relat. Res.. 2012 Sep;470(9):2462-75.

 

The rationale for using bisphosphonate (BP) therapy for Legg-Calvé-Perthes disease (LCPD) is the potential to prevent substantial femoral head deformity during the fragmentation phase by inhibiting osteoclastic bone resorption. However, it is unclear whether BP therapy decreases ...

Last Updated: 9 Aug 2012

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Racial and geographic factors in the incidence of Legg-Calvé-Perthes' disease: a systematic review.
 

Author(s): Daniel C Perry, David M G Machin, Daniel Pope, Colin E Bruce, Peter Dangerfield, Mary Jane Platt, Andrew J Hall

Journal: Am. J. Epidemiol.. 2012 Feb;175(3):159-66.

 

Legg-Calvé-Perthes' disease (Perthes' disease) is a childhood osteonecrosis of the hip for which the disease determinants are poorly understood. In this review, the authors identify studies of Perthes' disease incidence published up to December 2010 and make denominator populations ...

Last Updated: 20 Jan 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease
 

Status: Recruiting

Condition Summary: Legg Calve Perthes Disease

 

Last Updated: 1 Apr 2014

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Taperloc Complete Microplasty vs Taperloc Complete Standard: Randomized Controlled Study on Bone Mineral Density
 

Status: Recruiting

Condition Summary: Osteoarthritis; Avascular Necrosis; Traumatic Arthritis; Rheumatoid Arthritis; Legg-Perthes Disease

 

Last Updated: 2 Jul 2014

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Evaluate E1 Wear, Clinical Performance of E1 Liner in THA in Korean Patient Population
 

Status: Recruiting

Condition Summary: Osteoarthritis; Avascular Necrosis; Traumatic Arthritis; Rheumatoid Arthritis; Legg-perthes Disease

 

Last Updated: 2 Jul 2014

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