Laryngomalacia

Common Name(s)

Laryngomalacia

Laryngomalacia is an abnormality of the cartilage of the voice box (larynx) that is present at birth. The condition is characterized by "floppy" cartilage collapsing over the larynx when air is drawn into the lungs (inspiration), leading to airway obstruction. This obstruction causes a noise which may sound like nasal congestion or may be a more high-pitched sound (stridor). Airway sounds typically begin at 4-6 weeks of age. Affected infants have a higher risk of gastroesophageal reflux, and in severe cases may have feeding problems. In rare cases, hypoxemia or hypoventilation may interfere with normal growth and development. The cause of this condition is unknown, but it is thought to be due to delayed maturation of the supporting structures of the larynx. In more than 90% of cases it gradually improves on its own, and noises disappear by age 2 in virtually all infants.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Laryngomalacia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Laryngomalacia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Laryngomalacia" returned 13 free, full-text research articles on human participants. First 3 results:

Laryngomalacia: patient outcomes following aryepiglottoplasty at a tertiary care center.
 

Author(s): A Erim Pamuk, Nilda Süslü, R Onder Günaydın, Gamze Atay, Umut Akyol

Journal: Turk. J. Pediatr.. ;55(5):524-8.

 

Laryngomalacia is the most common cause of stridor in neonates and infants. Most cases are mild and resolve spontaneously without treatment. Only severe cases with intolerable symptoms require surgical intervention; in such cases, supraglottoplasty is considered the treatment of choice. ...

Last Updated: 2 Jan 2014

Go To URL
Surgical treatment of severe laryngomalacia: a retrospective study of 11 case.
 

Author(s): José Antonio Pinto, Henrique Wambier, Elcio Izumi Mizoguchi, Leonardo Marques Gomes, Rodrigo Kohler, Renata Coutinho Ribeiro

Journal: Braz J Otorhinolaryngol. ;79(5):564-8.

 

Laryngomalacia is the most frequent congenital abnormality of the larynx, accounting for approximately 60-75% of congenital stridor cases. Despite its benign and self-limited aspects, 10% of cases require intervention. Currently, supraglottoplasty is considered the standard treatment ...

Last Updated: 21 Oct 2013

Go To URL
Acquired idiopathic laryngomalacia treated by laser supraglottic laryngoplasty.
 

Author(s): Ai Kawamoto, Yukio Katori, Yohei Honkura, Masaki Ogura, Yoshitaka Takanashi, Toshimitsu Kobayashi

Journal: Tohoku J. Exp. Med.. 2013 ;230(1):43-7.

 

Laryngomalacia is the most common cause of stridor in neonates and infants, where the soft cartilages and tissues surrounding the upper larynx collapse inward during respiration. On the other hand, acquired idiopathic laryngomalacia in adults is quite rare, but should be borne in ...

Last Updated: 3 Jun 2013

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Laryngomalacia" returned 1 free, full-text review articles on human participants. First 3 results:

Management of laryngomalacia.
 

Author(s): S Ayari, G Aubertin, H Girschig, T Van Den Abbeele, F Denoyelle, V Couloignier, M Mondain

Journal: Eur Ann Otorhinolaryngol Head Neck Dis. 2013 Feb;130(1):15-21.

 

Laryngomalacia is the most common laryngeal disease of infancy. It is poorly tolerated in 10% of cases, requiring assessment and management, generally surgical. Surgery often consists of supraglottoplasty, for which a large number of technical variants have been described. This surgery, ...

Last Updated: 18 Feb 2013

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

The Yield of Laryngeal Ultrasound in the Diagnosis of Laryngomalacia
 

Status: Not yet recruiting

Condition Summary: Stridor; Laryngomalacia

 

Last Updated: 21 Nov 2013

Go to URL
Treatment of Exercise-induced Laryngomalacia in Elite Athletes
 

Status: Not yet recruiting

Condition Summary: Exercise-induced Laryngomalacia

 

Last Updated: 5 Nov 2013

Go to URL
Treatment of Children With Obstructive Sleep Apnea and Laryngomalacia: the Role of Laser Supraglottoplasty
 

Status: Recruiting

Condition Summary: Sleep Apnea, Obstructive; Respiration Disorders

 

Last Updated: 11 Jan 2015

Go to URL