Laryngomalacia

Common Name(s)

Laryngomalacia

Laryngomalacia is an abnormality of the cartilage of the voice box (larynx) that is present at birth. The condition is characterized by "floppy" cartilage collapsing over the larynx when air is drawn into the lungs (inspiration), leading to airway obstruction. This obstruction causes a noise which may sound like nasal congestion or may be a more high-pitched sound (stridor). Airway sounds typically begin at 4-6 weeks of age. Affected infants have a higher risk of gastroesophageal reflux, and in severe cases may have feeding problems. In rare cases, hypoxemia or hypoventilation may interfere with normal growth and development. The cause of this condition is unknown, but it is thought to be due to delayed maturation of the supporting structures of the larynx. In more than 90% of cases it gradually improves on its own, and noises disappear by age 2 in virtually all infants.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Laryngomalacia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Laryngomalacia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Laryngomalacia" returned 18 free, full-text research articles on human participants. First 3 results:

Congenital laryngomalacia is related to exercise-induced laryngeal obstruction in adolescence.
 

Author(s): Magnus Hilland, Ola Drange Røksund, Lorentz Sandvik, Øystein Haaland, Hans Jørgen Aarstad, Thomas Halvorsen, John-Helge Heimdal

Journal: Arch. Dis. Child.. 2016 May;101(5):443-8.

 

Congenital laryngomalacia (CLM) is the major cause of stridor in infants. Most cases are expected to resolve before 2 years of age, but long-term respiratory prospects are poorly described. We aimed to investigate if CLM was associated with altered laryngeal structure or function in later life.

Last Updated: 20 Apr 2016

Go To URL
Surgical treatment of a case of adult epiglottic laryngomalacia.
 

Author(s): M Bartolomeo, A Bigi, P Pelliccia, M Makeieff

Journal: Eur Ann Otorhinolaryngol Head Neck Dis. 2015 Feb;132(1):45-7.

 

Adult laryngomalacia is rare. It may be idiopathic or secondary to trauma or degenerative disease.

Last Updated: 20 Feb 2015

Go To URL
Laryngomalacia: patient outcomes following aryepiglottoplasty at a tertiary care center.
 

Author(s): A Erim Pamuk, Nilda Süslü, R Onder Günaydın, Gamze Atay, Umut Akyol

Journal: Turk. J. Pediatr.. ;55(5):524-8.

 

Laryngomalacia is the most common cause of stridor in neonates and infants. Most cases are mild and resolve spontaneously without treatment. Only severe cases with intolerable symptoms require surgical intervention; in such cases, supraglottoplasty is considered the treatment of choice. ...

Last Updated: 2 Jan 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Laryngomalacia" returned 1 free, full-text review articles on human participants. First 3 results:

Management of laryngomalacia.
 

Author(s): S Ayari, G Aubertin, H Girschig, T Van Den Abbeele, F Denoyelle, V Couloignier, M Mondain

Journal: Eur Ann Otorhinolaryngol Head Neck Dis. 2013 Feb;130(1):15-21.

 

Laryngomalacia is the most common laryngeal disease of infancy. It is poorly tolerated in 10% of cases, requiring assessment and management, generally surgical. Surgery often consists of supraglottoplasty, for which a large number of technical variants have been described. This surgery, ...

Last Updated: 18 Feb 2013

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

The Yield of Laryngeal Ultrasound in the Diagnosis of Laryngomalacia
 

Status: Not yet recruiting

Condition Summary: Stridor; Laryngomalacia

 

Last Updated: 21 Nov 2013

Go to URL
In Infants With Laryngomalacia, Does Acid-Blocking Medication Improve Respiratory Symptoms?
 

Status: Recruiting

Condition Summary: Laryngomalacia; Acid Reflux; Stridor

 

Last Updated: 4 Mar 2016

Go to URL
Treatment of Exercise-induced Laryngomalacia in Elite Athletes
 

Status: Not yet recruiting

Condition Summary: Exercise-induced Laryngomalacia

 

Last Updated: 5 Nov 2013

Go to URL