Laryngeal cancer

Common Name(s)

Laryngeal cancer

Laryngeal cancer is a rare form of cancer characterized by abnormal cell growth in the voice box. Cancerous cells in the voice box can lead to impairment in speaking. Additionally, abnormal cell growth in the voice box can easily spread to other parts of the body. Individuals with this disorder may experience symptoms such as breathing problems, fatigue, and higher frequency of illness. This condition can be diagnosed with a physical exam, imaging tests, and a biopsy, which is where a part of the tissue is removed to be looked at under a microscope. Treatment depends on the stage of the cancer. If the cancer has progressed, doctors may suggest patients undergo chemotherapy or radiotherapy to destroy cancerous larynx cells.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Laryngeal cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Laryngeal cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Laryngeal cancer" returned 186 free, full-text research articles on human participants. First 3 results:

Gene and protein expression of glucose transporter 1 and glucose transporter 3 in human laryngeal cancer-the relationship with regulatory hypoxia-inducible factor-1α expression, tumor invasiveness, and patient prognosis.
 

Author(s): Katarzyna Starska, Ewa Forma, Paweł Jóźwiak, Magdalena Bryś, Iwona Lewy-Trenda, Ewa Brzezińska-Błaszczyk, Anna Krześlak

Journal: Tumour Biol.. 2015 Apr;36(4):2309-21.

 

Increased glucose uptake mediated by glucose transporters and reliance on glycolysis are common features of malignant cells. Hypoxia-inducible factor-1α supports the adaptation of hypoxic cells by inducing genes related to glucose metabolism. The contribution of glucose transporter ...

Last Updated: 16 Apr 2015

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Overexpression of microRNA-30b improves adenovirus-mediated p53 cancer gene therapy for laryngeal carcinoma.
 

Author(s): Liang Li, Binquan Wang

Journal:

 

MicroRNAs play important roles in laryngeal carcinoma and other cancers. However, the expression of microRNAs in paracancerous tissue has been studied less. Here, using laser capture microdissection (LCM), we detected the expression of microRNAs in paracancerous tissues. Among all ...

Last Updated: 31 Oct 2014

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Effects of SNPs (CYP1B1*2 G355T, CYP1B1*3 C4326G, and CYP2E1*5 G-1293C), smoking, and drinking on susceptibility to laryngeal cancer among Han Chinese.
 

Author(s): Jianhua Jin, Faming Lin, Shiyu Liao, Qiyu Bao, Liyan Ni

Journal:

 

This study was conducted to explore the effects of genetic polymorphisms (CYP1B1*2 G355T, CYP1B1*3 C4326G, and CYP2E1*5 G-1293C) and environmental factors (smoking and drinking) on susceptibility to laryngeal cancer in a Han Chinese study group.

Last Updated: 10 Oct 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Laryngeal cancer" returned 17 free, full-text review articles on human participants. First 3 results:

Is there a role for intraoperative recurrent laryngeal nerve monitoring during high mediastinal lymph node dissection in three-stage oesophagectomy for oesophageal cancer?
 

Author(s): George Garas, Babar Kayani, Neil Tolley, Fausto Palazzo, Thanos Athanasiou, Emmanouil Zacharakis

Journal: Int J Surg. 2013 ;11(5):370-3.

 

A best evidence topic was written according to a structured protocol. The question addressed was whether there is a role for intraoperative recurrent laryngeal nerve monitoring during high mediastinal lymph node dissection in three-stage oesophagectomy for oesophageal cancer. A total ...

Last Updated: 13 May 2013

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Human papillomavirus infection and laryngeal cancer risk: a systematic review and meta-analysis.
 

Author(s): Xiangwei Li, Lei Gao, Huijun Li, Jing Gao, Yu Yang, Feng Zhou, Cong Gao, Mufei Li, Qi Jin

Journal: J. Infect. Dis.. 2013 Feb;207(3):479-88.

 

A number of molecular epidemiological studies have been conducted to explore the association of human papillomavirus (HPV) infection with laryngeal cancer. However, the findings are heterogeneous.

Last Updated: 7 Jan 2013

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Feasibility of intensity-modulated and image-guided radiotherapy for functional organ preservation in locally advanced laryngeal cancer.
 

Author(s): Nam P Nguyen, Alexander Chi, Michael Betz, Fabio Almeida, Paul Vos, Rick Davis, Benjamin Slane, Misty Ceizyk, Dave Abraham, Lexie Smith-Raymond, Michelle Stevie, Siyoung Jang, Steven Gelumbauskas, Vincent Vinh-Hung

Journal: PLoS ONE. 2012 ;7(8):e42729.

 

The study aims to assess the feasibility of intensity-modulated and image-guided radiotherapy (IMRT, and IGRT, respectively) for functional preservation in locally advanced laryngeal cancer. A retrospective review of 27 patients undergoing concurrent chemoradiation for locally advanced ...

Last Updated: 23 Aug 2012

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Observational Study of Swallowing Function After Treatment of Advanced Laryngeal Cancer
 

Status: Recruiting

Condition Summary: Squamous Cell Carcinoma; Laryngeal Cancer

 

Last Updated: 21 Aug 2014

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Last Updated: 10 Dec 2014

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Value of Narrow Band Imaging (NBI) Endoscopy in the Early Diagnosis of Laryngeal Cancer and Precancerous Lesions
 

Status: Recruiting

Condition Summary: Chronic Inflammation of Hypopharynx; Hoarseness; Macroscopic Laryngeal Lesions; Histological Confirmation of Dysplasia; Carcinoma in Situ; Invasive Carcinoma of Larynx; Invasive Carcinoma of Hypo Pharynx; Recurrent Respiratory Papillomatosis

 

Last Updated: 3 Mar 2015

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