Larsen syndrome

Common Name(s)

Larsen syndrome

Larsen syndrome is a condition that causes abnormal development of the bones. Signs and symptoms may include clubfoot and numerous joint dislocations at birth (affecting the hips, knees and elbows); flexible joints; and a distinctive appearance of the face, hands and feet. Larsen syndrome is inherited in an autosomal dominant manner and is caused by mutations in the FLNB gene. Management may include surgeries (especially for hip dislocation), and physiotherapy.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Larsen syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Larsen syndrome" returned 16 free, full-text research articles on human participants. First 3 results:

The management of knee dislocation in a child with Larsen syndrome.
 

Author(s): Ali Al Kaissi, Rudolf Ganger, Klaus Klaushofer, Franz Grill

Journal: Clinics (Sao Paulo). 2011 ;66(7):1295-9.

 

Last Updated: 30 Aug 2011

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Prenatal diagnosis of Larsen syndrome caused by a mutation in the filamin B gene.
 

Author(s): N Winer, F Kyndt, A Paumier, A David, B Isidor, M Quentin, B Jouitteau, P Sanyas, H J Philippe, A Hernandez, D Krakow, C Le Caignec

Journal: Prenat. Diagn.. 2009 Feb;29(2):172-4.

 

Last Updated: 5 Feb 2009

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Prenatally diagnosed lethal type Larsen-like syndrome associated with bifid tongue.
 

Author(s): Diclehan Orhan, Sevim Balci, Ozgür Deren, Eda Gülen Utine, Ahmet Başaran, Gülsev Kale

Journal: Turk. J. Pediatr.. ;50(4):395-9.

 

Larsen syndrome is characterized by multiple joint dislocations, associated with a typical facial appearance and frequently other abnormalities. Both dominant and recessive patterns of inheritance have been reported. A lethal form of Larsen syndrome (Larsen-like syndrome) has been ...

Last Updated: 18 Nov 2008

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Larsen syndrome" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Comparison of Three Treatments for Lower Extremity Apophysitis
 

Status: Recruiting

Condition Summary: Osgood-Schlatter Syndrome; Sinding-Larsen and Johansson Syndrome; Sever's Disease; Apophysitis

 

Last Updated: 5 Apr 2013

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