Large B cell diffuse lymphoma

Common Name(s)

Large B cell diffuse lymphoma

Large B cell diffuse lymphoma is a rare form of immune system cancer characterized by abnormal development and overproduction of B cells, a type of white blood cell. B cells are essential to the immune system because they produce antibodies that are responsible for recognizing foreign material and signalling the body to attack them. Individuals with this disorder may experience symptoms such as enlarged lymph nodes, fatigue, night sweats, and higher frequency of illness. Doctors often diagnose this form of cancer early, since symptoms are apparent. Treatment depends on the stage of the cancer. If the cancer has progressed, doctors may suggest patients undergo chemotherapy or radiotherapy to destroy cancerous B cells.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Large B cell diffuse lymphoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Large B cell diffuse lymphoma" returned 1104 free, full-text research articles on human participants. First 3 results:

Comparison of Three Chemotherapy Regimens in Elderly Patients with Diffuse Large B Cell Lymphoma: Experience at a Single National Reference Center in Mexico.
 

Author(s): Diana Nolasco-Medina, Nancy Reynoso-Noveron, Alejandro Mohar-Betancourt, Alejandro Aviles-Salas, Osvaldo García-Perez, Myrna Candelaria

Journal: Biomed Res Int. 2016 ;2016():9817606.

 

Background. Although chemotherapy added to rituximab is a standard of care for diffuse large B cell lymphoma (DLBCL), treatment of patients ≥65 years of age remains controversial due to comorbidities. Methods. This is a retrospective, comparative, nonrandomized study of patients ...

Last Updated: 1 Aug 2016

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Combinatorial epigenetic therapy in diffuse large B cell lymphoma pre-clinical models and patients.
 

Author(s): Benet Pera, Tiffany Tang, Rossella Marullo, Shao-Ning Yang, Haelee Ahn, Jayeshkumar Patel, Rebecca Elstrom, Jia Ruan, Richard Furman, John Leonard, Leandro Cerchietti, Peter Martin

Journal:

 

Refractory and/or relapsed diffuse large B cell lymphoma (RR-DLBCL) patients are incurable with conventional chemotherapy due to the aggressiveness and the chemorefractory state of these tumors. DNA hypermethylation and histone deacetylation are two major epigenetic modifications ...

Last Updated: 25 Jul 2016

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Single-agent MOR208 salvage and maintenance therapy in a patient with refractory/relapsing diffuse large B-cell lymphoma: a case report.
 

Author(s): Wojciech Jurczak, Agata Hanna Bryk, Patrycja Mensah, Krystyna Gałązka, Małgorzata Trofimiuk-Müldner, Łukasz Wyrobek, Anna Sawiec, Aleksander B Skotnicki

Journal:

 

Diffuse large B-cell lymphoma is the most common subtype of non-Hodgkin's lymphoma. Standard first-line treatment for this aggressive subtype comprises the anti-CD20 antibody rituximab combined with cyclophosphamide, doxorubicin, vincristine, and prednisone. If patients receiving ...

Last Updated: 14 May 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Large B cell diffuse lymphoma" returned 94 free, full-text review articles on human participants. First 3 results:

Clinicopathological features of primary hepatic diffuse large B-cell lymphoma: a report of seven cases and a literature review.
 

Author(s): Jinfeng Zheng, Yiliang Hou, Ruting Zhou, Dingrong Zhong

Journal:

 

We studied the imaging and histopathological features of primary hepatic diffuse large B-cell lymphoma in order to explore the clinicopathological features, diagnosis, differential diagnoses, and treatment. Immunolabelling was performed in seven cases of primary hepatic diffuse large ...

Last Updated: 1 Jan 2016

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Novel drug targets for personalized precision medicine in relapsed/refractory diffuse large B-cell lymphoma: a comprehensive review.
 

Author(s): Rosalba Camicia, Hans C Winkler, Paul O Hassa

Journal:

 

Diffuse large B-cell lymphoma (DLBCL) is a clinically heterogeneous lymphoid malignancy and the most common subtype of non-Hodgkin's lymphoma in adults, with one of the highest mortality rates in most developed areas of the world. More than half of DLBLC patients can be cured with ...

Last Updated: 15 Dec 2015

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Composite primary breast diffuse large B-cell lymphoma and T lymphoblastic leukemia/lymphoma: report of a case and review of literature.
 

Author(s): Chaoyang Guan, Jian Li, Peipei Xu, Jian Ouyang, Bing Chen

Journal:

 

We reported a rare case of composite diffuse large B-cell lymphoma and T lymphoblastic leukemia/lymphoma (T-LBL) in a 46-year-old woman with progressive enlargement of the breast lump. The patient initially sought care at a local hospital with a single left breast lump without any ...

Last Updated: 14 Oct 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study in Patients With Primary Breast Diffuse Large B-cell Lymphoma
 

Status: Recruiting

Condition Summary: Large B Cell Diffuse Lymphoma

 

Last Updated: 6 Jan 2017

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Occupational Exposure to Pesticides in the Prognosis of Lymphomas
 

Status: Recruiting

Condition Summary: Lymphoma Diffuse Large B-cell

 

Last Updated: 8 Sep 2016

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