Large B cell diffuse lymphoma

Common Name(s)

Large B cell diffuse lymphoma

Large B cell diffuse lymphoma is a rare form of immune system cancer characterized by abnormal development and overproduction of B cells, a type of white blood cell. B cells are essential to the immune system because they produce antibodies that are responsible for recognizing foreign material and signalling the body to attack them. Individuals with this disorder may experience symptoms such as enlarged lymph nodes, fatigue, night sweats, and higher frequency of illness. Doctors often diagnose this form of cancer early, since symptoms are apparent. Treatment depends on the stage of the cancer. If the cancer has progressed, doctors may suggest patients undergo chemotherapy or radiotherapy to destroy cancerous B cells.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Large B cell diffuse lymphoma" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Large B cell diffuse lymphoma" returned 1141 free, full-text research articles on human participants. First 3 results:

Primary diffuse large B cell lymphoma of the uterine cervix successfully treated by combined chemotherapy alone: A case report.
 

Author(s): Ana María Cubo, Zandra Mileny Soto, Miguel Ángel Cruz, María José Doyague, Verónica Sancho, Aurymar Fraino, Óscar Blanco, Noemi Puig, Miguel Alcoceba, Marcos González, José María Sayagués

Journal: Medicine (Baltimore). 2017 May;96(19):e6846.

 

Primary lymphomas of the uterine cervix are a rare disease. They are often misdiagnosed because of their rarity and because they can be easily confused with a squamous cell carcinoma of the cervix, as they are usually presented as exophytic mass with vaginal bleeding as their most ...

Last Updated: 10 May 2017

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The expression and clinical relevance of PD-1, PD-L1, and TP63 in patients with diffuse large B-cell lymphoma.
 

Author(s): Xia Fang, Bing Xiu, Zhizhang Yang, Weizhe Qiu, Long Zhang, Suxia Zhang, Yunjin Wu, Xuyou Zhu, Xue Chen, Suhong Xie, Xianghua Yi, Aibin Liang, Yu Zeng

Journal: Medicine (Baltimore). 2017 Apr;96(15):e6398.

 

Latest study showed that a novel translocation between programmed cell death ligand 1 (PD-L1) (cluster of differentiation 274) and TP63 (tumor protein 63) can be found in diffuse large B-cell lymphoma (DLBCL), resulting in their conjunct overexpression in tumor cells at RNA level. ...

Last Updated: 13 Apr 2017

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Orbital MALT Lymphoma after Autologous Stem Cell Transplantation for Follicular Lymphoma as Relapse of Diffuse Large B-Cell Lymphoma.
 

Author(s): Toshihiko Matsuo, Takehiro Tanaka, Nobuharu Fujii

Journal: J Clin Exp Hematop. 2017 ;56(3):170-175.

 

We report a patient who developed orbital MALT lymphoma after autologous peripheral blood stem cell transplantation for follicular lymphoma as relapse of diffuse large B-cell lymphoma. A 54-year-old woman with systemic lymphadenopathy was diagnosed with diffuse large B-cell lymphoma ...

Last Updated: 23 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Large B cell diffuse lymphoma" returned 98 free, full-text review articles on human participants. First 3 results:

Primary cutaneous diffuse large B cell lymphoma-other successfully treated by the combination of R-CHOP chemotherapy and surgery: A case report and review of literature.
 

Author(s): Jinjing Jia, Wensheng Li, Yan Zheng

Journal: Medicine (Baltimore). 2017 Feb;96(8):e6161.

 

The occurrence of primary cutaneous diffuse large B cell lymphoma-other (PCDLBCL-O) has been rarely reported in the literature. Its diagnosis is based on histopathological and immunohistochemical examinations. To improve the clinical diagnosis and treatment for PCDLBCL-O, we report ...

Last Updated: 22 Feb 2017

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Treatment of Diffuse Large B-Cell Lymphoma.
 

Author(s): Kana Miyazaki

Journal: J Clin Exp Hematop. 2016 ;56(2):79-88.

 

Diffuse large B-cell lymphoma (DLBCL) comprises a heterogeneous group with pathophysiological, genetic and clinical features. Many patients can be cured with R-CHOP therapy, which is the current standard regimen. Despite recent progress in improving patient survival, the 40% survival ...

Last Updated: 16 Dec 2016

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Molecular Pathogenesis of Diffuse Large B-Cell Lymphoma.
 

Author(s): Akito Dobashi

Journal: J Clin Exp Hematop. 2016 ;56(2):71-78.

 

Diffuse large B-cell lymphoma (DLBCL) is divided into germinal center B-like (GCB) DLBCL and activated B-like (ABC) DLBCL. In recent years, whole genome sequencing (WGS), whole exome sequencing (WES), and transcriptome sequencing (RNA-seq) have been performed for samples from many ...

Last Updated: 16 Dec 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study in Patients With Primary Breast Diffuse Large B-cell Lymphoma
 

Status: Recruiting

Condition Summary: Large B Cell Diffuse Lymphoma

 

Last Updated: 6 Jan 2017

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Idelalisib Post Allogeneic BMT in B Cell Derived Malignancies: A Phase 1 Toxicity Trial
 

Status: Recruiting

Condition Summary: B Cells--Tumors; B Cell Chronic Lymphocytic Leukemia; Follicular Lymphoma; Mantle Cell Lymphoma; Large B-cell Diffuse Lymphoma

 

Last Updated: 10 May 2017

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