Large B cell diffuse lymphoma

Common Name(s)

Large B cell diffuse lymphoma

Large B cell diffuse lymphoma is a rare form of immune system cancer characterized by abnormal development and overproduction of B cells, a type of white blood cell. B cells are essential to the immune system because they produce antibodies that are responsible for recognizing foreign material and signalling the body to attack them. Individuals with this disorder may experience symptoms such as enlarged lymph nodes, fatigue, night sweats, and higher frequency of illness. Doctors often diagnose this form of cancer early, since symptoms are apparent. Treatment depends on the stage of the cancer. If the cancer has progressed, doctors may suggest patients undergo chemotherapy or radiotherapy to destroy cancerous B cells.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Large B cell diffuse lymphoma" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Large B cell diffuse lymphoma" returned 1309 free, full-text research articles on human participants. First 3 results:

Sequential occurrence of diffuse large B-cell lymphoma and carcinoma in the nasopharynx: A case report.
 

Author(s): Yong Tae Hong, Ki Hwan Hong

Journal: Medicine (Baltimore). 2018 Jan;97(2):e9595.

 

The sequential occurrence of the 2 malignancies development of nasopharyngeal carcinoma (NPC) and lymphoma is extremely rare and their coexistence raises the question of a common etiologic factor.

Last Updated: 31 Dec 1969

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Prognostic significance of retention index of bone marrow on dual-phase 18F-fluorodeoxyglucose positron emission tomography/computed tomography in patients with diffuse large B-cell lymphoma.
 

Author(s): Chin-Chuan Chang, Shih-Feng Cho, Ya-Wen Chuang, Chia-Yang Lin, Ying-Fong Huang, Yu-Chang Tyan

Journal: Medicine (Baltimore). 2018 Jan;97(2):e9513.

 

The purpose of this study was to determine the prognostic significance of F-18 fluorodeoxyglucose (FDG) uptake on a dual-phase positron emission tomography/computed tomography (PET/CT), focusing on the increment in maximal standardized uptake value (SUVinc) of tumor and bone marrow ...

Last Updated: 31 Dec 1969

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Ratio of Immune Response to Tumor Burden Predicts Survival Via Regulating Functions of Lymphocytes and Monocytes in Diffuse Large B-Cell Lymphoma.
 

Author(s): Hongfei Ji, Xingjian Niu, Lei Yin, Yiran Wang, Lan Huang, Qijia Xuan, Liru Li, Han Zhang, Jingtong Li, Yue Yang, Weiwei An, Qingyuan Zhang

Journal: Cell. Physiol. Biochem.. 2018 ;45(3):951-961.

 

Diffuse large B-cell lymphoma (DLBCL) is an aggressive disease, and is the most common type of lymphoma in adults. Although significant progress in treatment has been made using chemotherapy combinations, there exist a large amount of relapse or refractory cases. Thus, effective clinical ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Large B cell diffuse lymphoma" returned 104 free, full-text review articles on human participants. First 3 results:

Isolated skeletal muscle recurrence of an originally nodal diffuse large B cell lymphoma: A case report and review of the literature.
 

Author(s): Nikolaos Spetsieris, Nefeli Giannakopoulou, Eleni Variami, Konstantinos Zervakis, Niki Rougala, Georgios Garefalakis, Vasiliki Skarlatou, Nora-Athina Viniou, Panagiotis Diamantopoulos

Journal: Medicine (Baltimore). 2018 Jan;97(3):e9608.

 

Diffuse large B cell lymphoma (DLBCL) is a malignancy of the B cells with extranodal primary involvement being estimated at 30% to 40% of cases. Primary skeletal muscle presentation of DLBCL is extremely rare, with an estimated incidence of about 0.5% of extranodal lymphomas, presenting ...

Last Updated: 31 Dec 1969

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CT and PET/CT findings of primary pulmonary diffuse large B-cell lymphoma: One case report and literature review.
 

Author(s): Yanjun Bai, Wenjie Liang

Journal: Medicine (Baltimore). 2017 Nov;96(47):e8876.

 

Primary pulmonary diffuse large B-cell lymphoma (PPL-DLBCL) is rare and its clinical manifestations lack specificity. In this report, we present one case of PPL-DLBCL with complete clinical and imaging data, including uncontrast-enhanced CT, contrast-enhanced CT, and positron emission ...

Last Updated: 31 Dec 1969

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Diffuse large B-cell lymphoma: can genomics improve treatment options for a curable cancer?
 

Author(s): Amit Dipak Amin, Tara L Peters, Lingxiao Li, Soumya Sundara Rajan, Ramesh Choudhari, Soham D Puvvada, Jonathan H Schatz

Journal: Cold Spring Harb Mol Case Stud. 2017 May;3(3):a001719.

 

Gene-expression profiling and next-generation sequencing have defined diffuse large B-cell lymphoma (DLBCL), the most common lymphoma diagnosis, as a heterogeneous group of subentities. Despite ongoing explosions of data illuminating disparate pathogenic mechanisms, however, the five-drug ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Oral Azacitidine Plus Salvage Chemotherapy in Relapsed/Refractory Diffuse Large B Cell Lymphoma
 

Status: Not yet recruiting

Condition Summary: Large B-Cell Diffuse Lymphoma

 

Last Updated: 27 Feb 2018

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Idelalisib Post Allogeneic Hematopoietic Stem Cell Transplant (HSCT) in B Cell Derived Malignancies: A Phase 1 Double Blinded Randomized Placebo Toxicity Trial"
 

Status: Not yet recruiting

Condition Summary: B Cells-Tumors; B Cell Chronic Lymphocytic Leukemia; Follicular Lymphoma; Mantle Cell Lymphoma; Large B-Cell Diffuse Lymphoma of Bone (Diagnosis)

 

Last Updated: 16 Apr 2018

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