Large B cell diffuse lymphoma

Common Name(s)

Large B cell diffuse lymphoma

Large B cell diffuse lymphoma is a rare form of immune system cancer characterized by abnormal development and overproduction of B cells, a type of white blood cell. B cells are essential to the immune system because they produce antibodies that are responsible for recognizing foreign material and signalling the body to attack them. Individuals with this disorder may experience symptoms such as enlarged lymph nodes, fatigue, night sweats, and higher frequency of illness. Doctors often diagnose this form of cancer early, since symptoms are apparent. Treatment depends on the stage of the cancer. If the cancer has progressed, doctors may suggest patients undergo chemotherapy or radiotherapy to destroy cancerous B cells.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Large B cell diffuse lymphoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Large B cell diffuse lymphoma" returned 1132 free, full-text research articles on human participants. First 3 results:

Imaging by ¹⁸F-FDG PET/CT of diffuse large B-cell lymphoma with cellulitis.
 

Author(s): Yiqiu Zhang, Beilei Li, Liang Cai, Hongcheng Shi, Jun Hou

Journal: Hell J Nucl Med. ;18(3):271-2.

 

Non-Hodgkin's lymphomas (NHL) quite often present in the neck but are seldom accompanied with cellulitis at the first diagnosis of the disease. We report a 56 year old woman with gradually neck swelling, which was initially treated as cellulitis. After examined by ultrasonography, ...

Last Updated: 5 Dec 2015

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Prediction of Central Nervous System Relapse of Diffuse Large B-Cell Lymphoma Using Pretherapeutic [18F]2-Fluoro-2-Deoxyglucose (FDG) Positron Emission Tomography/Computed Tomography.
 

Author(s): Yoo Sung Song, Won Woo Lee, Jong Seok Lee, Sang Eun Kim

Journal: Medicine (Baltimore). 2015 Nov;94(44):e1978.

 

Central nervous system (CNS) relapse of diffuse large B-cell lymphoma (DLBCL) is a rare complication, but has a poor prognosis with unknown pathophysiology. Recent trials of CNS prophylaxis have shown to be ineffective, despite patient's selection using several known clinical risk ...

Last Updated: 11 Nov 2015

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Evaluation of immunohistochemical subtypes in diffuse large B-cell lymphoma and its impact on survival.
 

Author(s): Anamika Dwivedi, Anurag Mehta, Poonam Solanki

Journal: Indian J Pathol Microbiol. ;58(4):453-8.

 

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma in Indian population. The disease could be divided into the prognostically important subtypes, germinal center B-cell (GCB)-like and activated B-cell-like, using gene expression profiling (GEP). ...

Last Updated: 9 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Large B cell diffuse lymphoma" returned 94 free, full-text review articles on human participants. First 3 results:

Immune-mediated Neuropathy with Anti-disialosyl IgM Antibodies in Diffuse Large B-cell Lymphoma: A Case Report and Literature Review.
 

Author(s): Gen Shihashi, Takuya Yagi, Shigeaki Suzuki, Morinobu Seki, Sumiko Kohashi, Tomoki Ueda, Kaori Kameyama, Susumu Kusunoki, Hideaki Nakajima, Shinichiro Okamoto, Norihiro Suzuki

Journal: Intern. Med.. 2015 ;54(13):1647-51.

 

A 36-year-old man with diffuse large B-cell lymphoma presented with polyneuropathy, and the diagnostic work-up revealed the presence of IgM antibodies against gangliosides with disialosyl residues (GD1b, GD3). He was treated with rituximab, cyclophosphamide, doxorubicin, vincristine, ...

Last Updated: 3 Jul 2015

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Spontaneous Regression of Refractory Diffuse Large B-Cell Lymphoma with Improvement in Immune Status with ART in a Patient with HIV: A Case Report and Literature Review.
 

Author(s): K C Birendra, Muhammad Zubair Afzal, Katherine A Wentland, Hamza Hashmi, Sudhir Singh, Elena Ivan, Nehal Lakhani

Journal:

 

Diffuse large B-cell lymphoma accounts for the large majority of AIDS-related non-Hodgkin lymphoma. Traditionally, this lymphoma has been treated with CHOP-like regimens with the recent addition of rituximab. We report a unique case where an HIV-infected patient with diffuse large ...

Last Updated: 6 Jun 2015

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Cell-of-Origin in Diffuse Large B-Cell Lymphoma: Are the Assays Ready for the Clinic?
 

Author(s): David W Scott

Journal: Am Soc Clin Oncol Educ Book. 2015 ;():e458-66.

 

Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma worldwide and consists of a heterogeneous group of cancers classified together on the basis of shared morphology, immunophenotype, and aggressive clinical behavior. It is now recognized that this malignancy comprises ...

Last Updated: 21 May 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study in Patients With Primary Breast Diffuse Large B-cell Lymphoma
 

Status: Recruiting

Condition Summary: Large B Cell Diffuse Lymphoma

 

Last Updated: 5 Feb 2016

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FLT-PET/CT vs FDG-PET/CT for Therapy Monitoring of Diffuse Large B-cell Lymphoma
 

Status: Recruiting

Condition Summary: Lymphoma; Lymphoma, Non-Hodgkin; Large B Cell Diffuse Lymphoma

 

Last Updated: 14 Feb 2014

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Last Updated: 10 Mar 2016

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