Large B cell diffuse lymphoma

Common Name(s)

Large B cell diffuse lymphoma

Large B cell diffuse lymphoma is a rare form of immune system cancer characterized by abnormal development and overproduction of B cells, a type of white blood cell. B cells are essential to the immune system because they produce antibodies that are responsible for recognizing foreign material and signalling the body to attack them. Individuals with this disorder may experience symptoms such as enlarged lymph nodes, fatigue, night sweats, and higher frequency of illness. Doctors often diagnose this form of cancer early, since symptoms are apparent. Treatment depends on the stage of the cancer. If the cancer has progressed, doctors may suggest patients undergo chemotherapy or radiotherapy to destroy cancerous B cells.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Large B cell diffuse lymphoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Large B cell diffuse lymphoma" returned 1194 free, full-text research articles on human participants. First 3 results:

Anti-CD19 CAR T Cells in CNS Diffuse Large-B-Cell Lymphoma.
 

Author(s): Jeremy S Abramson, Brianne McGree, Sarah Noyes, Sean Plummer, Curtis Wong, Yi-Bin Chen, Edwin Palmer, Tina Albertson, Judith A Ferry, Isabel C Arrillaga-Romany

Journal: N. Engl. J. Med.. 2017 08;377(8):783-784.

 

Last Updated: 23 Aug 2017

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Treatment outcome of diffuse large B-cell lymphoma involving the head and neck: Two-institutional study for the significance of radiotherapy after R-CHOP chemotherapy.
 

Author(s): Yoo-Kang Kwak, Byung-Ock Choi, Sung Hwan Kim, Joo Hwan Lee, Dae Gyu Kang, Jong Hoon Lee

Journal: Medicine (Baltimore). 2017 Jun;96(25):e7268.

 

This study was performed to analyze the treatment outcome for diffuse large B-cell lymphoma (DLBCL) involving the head and neck and to evaluate the role of radiotherapy in the rituximab era. Fifty-six patients diagnosed with DLBCL involving the head and neck were assessed. All patients ...

Last Updated: 22 Jun 2017

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High KIF2A expression predicts unfavorable prognosis in diffuse large B cell lymphoma.
 

Author(s): Yaping Zhang, Xuefen You, Hong Liu, Mengqi Xu, Qingxiu Dang, Li Yang, Jianfei Huang, Wenyu Shi

Journal: Ann. Hematol.. 2017 Sep;96(9):1485-1491.

 

Kinesin family member 2A (KIF2A), a conserved motor protein, plays a critical role in the pathogenesis and prognosis of several malignant tumors. The aim of the present study was to investigate KIF2A expression in diffuse large B cell lymphoma (DLBCL), evaluate the association between ...

Last Updated: 15 Jun 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Large B cell diffuse lymphoma" returned 100 free, full-text review articles on human participants. First 3 results:

Primary cutaneous diffuse large B cell lymphoma-other successfully treated by the combination of R-CHOP chemotherapy and surgery: A case report and review of literature.
 

Author(s): Jinjing Jia, Wensheng Li, Yan Zheng

Journal: Medicine (Baltimore). 2017 Feb;96(8):e6161.

 

The occurrence of primary cutaneous diffuse large B cell lymphoma-other (PCDLBCL-O) has been rarely reported in the literature. Its diagnosis is based on histopathological and immunohistochemical examinations. To improve the clinical diagnosis and treatment for PCDLBCL-O, we report ...

Last Updated: 22 Feb 2017

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Diffuse Large B-Cell Lymphoma in the Era of Precision Oncology: How Imaging Is Helpful.
 

Author(s): Hina J Shah, Abhishek R Keraliya, Jyothi P Jagannathan, Sree Harsha Tirumani, Vikram R Lele, Pamela J DiPiro

Journal: Korean J Radiol. ;18(1):54-70.

 

Diffuse large B cell lymphoma (DLBCL) is the most common histological subtype of Non-Hodgkin's lymphoma. As treatments continues to evolve, so do imaging strategies, and positron emission tomography (PET) has emerged as the most important imaging tool to guide oncologists in the diagnosis, ...

Last Updated: 18 Jan 2017

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Treatment of Diffuse Large B-Cell Lymphoma.
 

Author(s): Kana Miyazaki

Journal: J Clin Exp Hematop. 2016 ;56(2):79-88.

 

Diffuse large B-cell lymphoma (DLBCL) comprises a heterogeneous group with pathophysiological, genetic and clinical features. Many patients can be cured with R-CHOP therapy, which is the current standard regimen. Despite recent progress in improving patient survival, the 40% survival ...

Last Updated: 16 Dec 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Idelalisib Post Allogeneic BMT in B Cell Derived Malignancies: A Phase 1 Toxicity Trial
 

Status: Recruiting

Condition Summary: B Cells--Tumors; B Cell Chronic Lymphocytic Leukemia; Follicular Lymphoma; Mantle Cell Lymphoma; Large B-cell Diffuse Lymphoma

 

Last Updated: 10 May 2017

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Occupational Exposure to Pesticides in the Prognosis of Lymphomas
 

Status: Recruiting

Condition Summary: Lymphoma Diffuse Large B-cell

 

Last Updated: 8 Sep 2016

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