Large B cell diffuse lymphoma

Common Name(s)

Large B cell diffuse lymphoma

Large B cell diffuse lymphoma is a rare form of immune system cancer characterized by abnormal development and overproduction of B cells, a type of white blood cell. B cells are essential to the immune system because they produce antibodies that are responsible for recognizing foreign material and signalling the body to attack them. Individuals with this disorder may experience symptoms such as enlarged lymph nodes, fatigue, night sweats, and higher frequency of illness. Doctors often diagnose this form of cancer early, since symptoms are apparent. Treatment depends on the stage of the cancer. If the cancer has progressed, doctors may suggest patients undergo chemotherapy or radiotherapy to destroy cancerous B cells.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Large B cell diffuse lymphoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Large B cell diffuse lymphoma" returned 1142 free, full-text research articles on human participants. First 3 results:

A20 Mutation Is Not a Prognostic Marker for Activated B-Cell-Like Diffuse Large B-Cell Lymphoma.
 

Author(s): Hong Cen, Xiaohong Tan, Baoping Guo

Journal:

 

Constitutive activation of nuclear factor κB (NF-κB) is a hallmark of activated B-cell-like diffuse large B-cell lymphoma (ABC-DLBCL). Mutations in the A20 gene activate NF-κB, but the prognostic value of A20 mutations in ABC-DLBLC is unclear.

Last Updated: 31 Dec 2015

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The Prognostic Role and Relationship between E2F1 and SV40 in Diffuse Large B-Cell Lymphoma of Egyptian Patients.
 

Author(s): Rehab M Samaka, Hayam A Aiad, Mona A Kandil, Nancy Y Asaad, Nanes S Holah

Journal: Anal Cell Pathol (Amst). 2015 ;2015():919834.

 

Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphomas worldwide. The pathogenesis of lymphomas is not yet well understood. SV40 induces malignant transformation by the large T-antigen (L-TAG) and promotes transformation by binding and inactivating p53 and pRb. ...

Last Updated: 25 Nov 2015

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Imaging by ¹⁸F-FDG PET/CT of diffuse large B-cell lymphoma with cellulitis.
 

Author(s): Yiqiu Zhang, Beilei Li, Liang Cai, Hongcheng Shi, Jun Hou

Journal: Hell J Nucl Med. ;18(3):271-2.

 

Non-Hodgkin's lymphomas (NHL) quite often present in the neck but are seldom accompanied with cellulitis at the first diagnosis of the disease. We report a 56 year old woman with gradually neck swelling, which was initially treated as cellulitis. After examined by ultrasonography, ...

Last Updated: 5 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Large B cell diffuse lymphoma" returned 96 free, full-text review articles on human participants. First 3 results:

Primary renal diffuse large B-cell lymphoma with central nervous system involvement: a rare case report and literature review.
 

Author(s): Ying Wang, Shuangshuang Guo

Journal:

 

Primary renal lymphoma is a rare entity. Of these, diffuse large B-cell lymphoma is the most common pathological type and, R-CHOP regimen was the preferred chemotherapy for it. Here we present an adult case of primary renal diffuse large B-cell lymphoma.

Last Updated: 11 Aug 2015

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Immune-mediated Neuropathy with Anti-disialosyl IgM Antibodies in Diffuse Large B-cell Lymphoma: A Case Report and Literature Review.
 

Author(s): Gen Shihashi, Takuya Yagi, Shigeaki Suzuki, Morinobu Seki, Sumiko Kohashi, Tomoki Ueda, Kaori Kameyama, Susumu Kusunoki, Hideaki Nakajima, Shinichiro Okamoto, Norihiro Suzuki

Journal: Intern. Med.. 2015 ;54(13):1647-51.

 

A 36-year-old man with diffuse large B-cell lymphoma presented with polyneuropathy, and the diagnostic work-up revealed the presence of IgM antibodies against gangliosides with disialosyl residues (GD1b, GD3). He was treated with rituximab, cyclophosphamide, doxorubicin, vincristine, ...

Last Updated: 3 Jul 2015

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Spontaneous Regression of Refractory Diffuse Large B-Cell Lymphoma with Improvement in Immune Status with ART in a Patient with HIV: A Case Report and Literature Review.
 

Author(s): K C Birendra, Muhammad Zubair Afzal, Katherine A Wentland, Hamza Hashmi, Sudhir Singh, Elena Ivan, Nehal Lakhani

Journal:

 

Diffuse large B-cell lymphoma accounts for the large majority of AIDS-related non-Hodgkin lymphoma. Traditionally, this lymphoma has been treated with CHOP-like regimens with the recent addition of rituximab. We report a unique case where an HIV-infected patient with diffuse large ...

Last Updated: 6 Jun 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study in Patients With Primary Breast Diffuse Large B-cell Lymphoma
 

Status: Recruiting

Condition Summary: Large B Cell Diffuse Lymphoma

 

Last Updated: 5 Feb 2016

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FLT-PET/CT vs FDG-PET/CT for Therapy Monitoring of Diffuse Large B-cell Lymphoma
 

Status: Recruiting

Condition Summary: Lymphoma; Lymphoma, Non-Hodgkin; Large B Cell Diffuse Lymphoma

 

Last Updated: 14 Feb 2014

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Last Updated: 10 Mar 2016

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