Large B cell diffuse lymphoma

Common Name(s)

Large B cell diffuse lymphoma

Large B cell diffuse lymphoma is a rare form of immune system cancer characterized by abnormal development and overproduction of B cells, a type of white blood cell. B cells are essential to the immune system because they produce antibodies that are responsible for recognizing foreign material and signalling the body to attack them. Individuals with this disorder may experience symptoms such as enlarged lymph nodes, fatigue, night sweats, and higher frequency of illness. Doctors often diagnose this form of cancer early, since symptoms are apparent. Treatment depends on the stage of the cancer. If the cancer has progressed, doctors may suggest patients undergo chemotherapy or radiotherapy to destroy cancerous B cells.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Large B cell diffuse lymphoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Large B cell diffuse lymphoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Large B cell diffuse lymphoma" returned 937 free, full-text research articles on human participants. First 3 results:

Prognosis of patients with diffuse large B cell lymphoma not reaching complete response or relapsing after frontline chemotherapy or immunochemotherapy.
 

Author(s): Jordina Rovira, Alexandra Valera, Lluis Colomo, Xavier Setoain, Sonia Rodríguez, Alejandra Martínez-Trillos, Eva Giné, Ivan Dlouhy, Laura Magnano, Anna Gaya, Daniel Martínez, Antonio Martínez, Elías Campo, Armando López-Guillermo

Journal: Ann. Hematol.. 2015 May;94(5):803-12.

 

A retrospective study was performed to assess the outcome of patients with diffuse large B cell lymphoma (DLBCL) who did not achieve complete response or who relapsed before and after the use of rituximab. Clinical features and outcome of 816 (425 M/391 F; median age 63 years) patients ...

Last Updated: 26 Mar 2015

Go To URL
Fatal visceral varicella-zoster developing early after autologous hematopoietic stem cell transplantation for refractory diffuse large B-cell lymphoma.
 

Author(s): Satoshi Ichikawa, Mihyun Kim, Shin Hasegawa, Keiichi Ohashi, Aiko Kondo, Hiroki Kato, Mayumi Kamata, Yoko Okitsu, Noriko Fukuhara, Yasushi Onishi, Kenichi Ishizawa, Hideo Harigae

Journal: J Clin Exp Hematop. 2014 ;54(3):237-41.

 

A middle-aged woman who had undergone autologous hematopoietic stem cell transplantation (HSCT) 1 month previously suffered severe epigastralgia and relapse of lymphoma. The epigastralgia was not relieved by chemotherapy. Thereafter, her pancreatic and hepatic enzyme levels were markedly ...

Last Updated: 16 Dec 2014

Go To URL
Comment on: "clinical features, management, and prognosis of an international series of 161 patients with limited-stage diffuse large B-cell lymphoma of the bone (the IELSG-14 Study)".
 

Author(s): Richard Hoppe, Tim Illidge, Lena Specht, Ivan Vogelius, Joachim Yahalom

Journal: Oncologist. 2014 Dec;19(12):1289.

 

Last Updated: 6 Dec 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Large B cell diffuse lymphoma" returned 84 free, full-text review articles on human participants. First 3 results:

Rituximab treatment strategy for patients with diffuse large B-cell lymphoma after first-line therapy: a systematic review and meta-analysis.
 

Author(s): Yuan-Rong Ren, Yong-Dong Jin, Zhi-Hui Zhang, Li Li, Ping Wu

Journal: Chin. Med. J.. 2015 Feb;128(3):378-83.

 

Rituximab in combination with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) significantly prolonged event-free survival in first-line chemotherapy for patients with diffuse large B-cell lymphoma (DLBCL). But relapse and refractory DLBCL occur frequently. Although ...

Last Updated: 31 Jan 2015

Go To URL
Synchronous bilateral non-Hodgkin's diffuse large B-cell lymphoma of the breast and left breast invasive ductal carcinoma: a case report and review of literature.
 

Author(s): Weihua Liu, Hong Zhu, Xiaoge Zhou

Journal:

 

Lymphoma of the breast is unusual, and synchronous bilateral lymphoma and carcinoma of the breast is extremely rare. We present the case of a 51-year-old woman who found a mass in her left breast. Ultrasound scan findings revealed nodules at the 2 o'clock position in her left breast ...

Last Updated: 17 Nov 2014

Go To URL
[Primary bone marrow diffuse large B cell lymphoma: three case reports and literature review].
 

Author(s): Huimin Liu, Shuhua Yi, Enbin Liu, Zengjun Li, Hongju Zhang, Kun Ru, Dehui Zou, Lugui Qiu

Journal: Zhonghua Xue Ye Xue Za Zhi. 2014 Oct;35(10):914-7.

 

To report the diagnosis, differential diagnosis and treatment of three rare cases of primary bone marrow diffuse large B cell lymphoma (DLBCL), and to improve the recognition of this disease.

Last Updated: 23 Oct 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Study in Patients With Primary Breast Diffuse Large B-cell Lymphoma
 

Status: Recruiting

Condition Summary: Large B Cell Diffuse Lymphoma

 

Last Updated: 22 Jul 2015

Go to URL
FLT-PET/CT vs FDG-PET/CT for Therapy Monitoring of Diffuse Large B-cell Lymphoma
 

Status: Recruiting

Condition Summary: Lymphoma; Lymphoma, Non-Hodgkin; Large B Cell Diffuse Lymphoma

 

Last Updated: 14 Feb 2014

Go to URL
ACP-196, a Btk Inhibitor, for Treatment of de Novo Activated B-cell (ABC) Subtype of Diffuse Large B-Cell Lymphoma
 

Status: Recruiting

Condition Summary: Activated B-cell Diffuse Large B-Cell Lymphoma (ABC DLBCL)

 

Last Updated: 11 Feb 2015

Go to URL