Large B cell diffuse lymphoma

Common Name(s)

Large B cell diffuse lymphoma

Large B cell diffuse lymphoma is a rare form of immune system cancer characterized by abnormal development and overproduction of B cells, a type of white blood cell. B cells are essential to the immune system because they produce antibodies that are responsible for recognizing foreign material and signalling the body to attack them. Individuals with this disorder may experience symptoms such as enlarged lymph nodes, fatigue, night sweats, and higher frequency of illness. Doctors often diagnose this form of cancer early, since symptoms are apparent. Treatment depends on the stage of the cancer. If the cancer has progressed, doctors may suggest patients undergo chemotherapy or radiotherapy to destroy cancerous B cells.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Large B cell diffuse lymphoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Large B cell diffuse lymphoma" returned 1246 free, full-text research articles on human participants. First 3 results:

More on Anti-CD19 CAR T Cells in CNS Diffuse Large-B-Cell Lymphoma.
 

Author(s): Jeremy S Abramson, Yi-Bin Chen

Journal: N. Engl. J. Med.. 2017 11;377(21):2102.

 

Last Updated: 31 Dec 1969

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Tumor and bone marrow uptakes on [18F]fluorodeoxyglucose positron emission tomography/computed tomography predict prognosis in patients with diffuse large B-cell lymphoma receiving rituximab-containing chemotherapy.
 

Author(s): Chin-Chuan Chang, Shih-Feng Cho, Hung-Pin Tu, Chia-Yang Lin, Ya-Wen Chuang, Shu-Min Chang, Wen-Ling Hsu, Ying-Fong Huang

Journal: Medicine (Baltimore). 2017 Nov;96(45):e8655.

 

The purpose of this study was to determine the relevance of standardized uptake value (SUV) on [F]fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT), focusing on tumor and bone marrow, to disease outcomes based on progression-free survival (PFS) and ...

Last Updated: 31 Dec 1969

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Efficacy of rituximab combined with CHOP for treating patients with diffuse large B-cell lymphoma.
 

Author(s): Xin Hu, Min Zeng, Shun-E Yang, Xiao Liang, Shan-Shan Ding, Li Guo, Shan Li, Shu-Juan Wen

Journal: Medicine (Baltimore). 2017 Nov;96(45):e8494.

 

This study aimed to evaluate the efficacy and safety of rituximab combined with cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) for treating patients with diffuse large B-cell lymphoma (DLBCL).

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Large B cell diffuse lymphoma" returned 101 free, full-text review articles on human participants. First 3 results:

Diffuse large B-cell lymphoma: can genomics improve treatment options for a curable cancer?
 

Author(s): Amit Dipak Amin, Tara L Peters, Lingxiao Li, Soumya Sundara Rajan, Ramesh Choudhari, Soham D Puvvada, Jonathan H Schatz

Journal: Cold Spring Harb Mol Case Stud. 2017 May;3(3):a001719.

 

Gene-expression profiling and next-generation sequencing have defined diffuse large B-cell lymphoma (DLBCL), the most common lymphoma diagnosis, as a heterogeneous group of subentities. Despite ongoing explosions of data illuminating disparate pathogenic mechanisms, however, the five-drug ...

Last Updated: 31 Dec 1969

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Primary Pulmonary Diffuse Large B Cell Non-Hodgkin's Lymphoma: A Case Report and Literature Review.
 

Author(s): Ziqiang Zhu, Wei Liu, Omar Mamlouk, James E O'Donnell, Debabrata Sen, Boris Avezbakiyev

Journal:

 

BACKGROUND Primary pulmonary diffuse large B cell lymphoma (DLBCL) is extremely rare neoplasm representing only 0.5-1% of primary pulmonary malignancies. These patients usually have non-specific clinical presentation and radiological findings. Therefore, it is important to increase ...

Last Updated: 31 Dec 1969

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Primary cutaneous diffuse large B cell lymphoma-other successfully treated by the combination of R-CHOP chemotherapy and surgery: A case report and review of literature.
 

Author(s): Jinjing Jia, Wensheng Li, Yan Zheng

Journal: Medicine (Baltimore). 2017 Feb;96(8):e6161.

 

The occurrence of primary cutaneous diffuse large B cell lymphoma-other (PCDLBCL-O) has been rarely reported in the literature. Its diagnosis is based on histopathological and immunohistochemical examinations. To improve the clinical diagnosis and treatment for PCDLBCL-O, we report ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Trial of R-GemOx Versus R-miniCHOP Regimen in First-line Treatment of Elderly Diffuse Large B Cell Lymphoma
 

Status: Recruiting

Condition Summary: Diffuse Large B Cell Lymphoma

 

Last Updated: 7 May 2016

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Chidamide Combined With VDDT Regimen in the Relapse and Refractory Diffuse Large B Cell Lymphoma
 

Status: Recruiting

Condition Summary: Diffuse Large B-cell Lymphoma

 

Last Updated: 1 May 2016

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