Large B cell diffuse lymphoma

Common Name(s)

Large B cell diffuse lymphoma

Large B cell diffuse lymphoma is a rare form of immune system cancer characterized by abnormal development and overproduction of B cells, a type of white blood cell. B cells are essential to the immune system because they produce antibodies that are responsible for recognizing foreign material and signalling the body to attack them. Individuals with this disorder may experience symptoms such as enlarged lymph nodes, fatigue, night sweats, and higher frequency of illness. Doctors often diagnose this form of cancer early, since symptoms are apparent. Treatment depends on the stage of the cancer. If the cancer has progressed, doctors may suggest patients undergo chemotherapy or radiotherapy to destroy cancerous B cells.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Large B cell diffuse lymphoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Large B cell diffuse lymphoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Large B cell diffuse lymphoma" returned 1064 free, full-text research articles on human participants. First 3 results:

Prognostic and Clinicopathological Value of Survivin in Diffuse Large B-cell Lymphoma: A Meta-Analysis.
 

Author(s): Ya Zhang, Jianhong Wang, Xiaohui Sui, Ying Li, Kang Lu, Xiaosheng Fang, Yujie Jiang, Xin Wang

Journal: Medicine (Baltimore). 2015 Sep;94(36):e1432.

 

Up to date, survivin, a well-known inhibitor of apoptosis, has attracted considerable attention as a potential biomarker and therapeutic target in diffuse large B-cell lymphoma (DLBCL). Nevertheless, there still remains no consensus on heterogeneous results. Herein, a meta-analysis ...

Last Updated: 11 Sep 2015

Go To URL
Primary Pulmonary Diffuse Large B-Cell Lymphoma on FDG PET/CT-MRI and DWI.
 

Author(s): Huiting Xu, Kai Xu, Ru Wang, Xiaohua Liu

Journal: Medicine (Baltimore). 2015 Jul;94(29):e1210.

 

Primary pulmonary diffuse large B-cell lymphoma (PPDLBCL) directly arising from lung tissue is extremely rare. It may usually be misdiagnosed as inflammation including pulmonary tuberculosis, even lung cancer, because its clinical symptoms and signs are often nonspecific. The final ...

Last Updated: 23 Jul 2015

Go To URL
Rituximab maintenance therapy in diffuse large B-cell lymphoma: is XY the most important variable?
 

Author(s): Matthew A Lunning, James O Armitage

Journal: Haematologica. 2015 Jul;100(7):853-5.

 

Last Updated: 1 Jul 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Large B cell diffuse lymphoma" returned 89 free, full-text review articles on human participants. First 3 results:

Immune-mediated Neuropathy with Anti-disialosyl IgM Antibodies in Diffuse Large B-cell Lymphoma: A Case Report and Literature Review.
 

Author(s): Gen Shihashi, Takuya Yagi, Shigeaki Suzuki, Morinobu Seki, Sumiko Kohashi, Tomoki Ueda, Kaori Kameyama, Susumu Kusunoki, Hideaki Nakajima, Shinichiro Okamoto, Norihiro Suzuki

Journal: Intern. Med.. 2015 ;54(13):1647-51.

 

A 36-year-old man with diffuse large B-cell lymphoma presented with polyneuropathy, and the diagnostic work-up revealed the presence of IgM antibodies against gangliosides with disialosyl residues (GD1b, GD3). He was treated with rituximab, cyclophosphamide, doxorubicin, vincristine, ...

Last Updated: 3 Jul 2015

Go To URL
The Role of Consolidative Radiotherapy after a Complete Response to Chemotherapy in the Treatment of Diffuse Large B-Cell Lymphoma in the Rituximab Era: Results from a Systematic Review with a Meta-Analysis.
 

Author(s): Chunhong Hu, Chao Deng, Wen Zou, Guangsen Zhang, Jingjing Wang

Journal: Acta Haematol.. 2015 ;134(2):111-8.

 

The current standard therapy for patients with diffuse large B-cell lymphoma (DLBCL) is rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone (RCHOP). The role of radiotherapy (RT) after complete response (CR) to RCHOP in patients with DLBCL remains unclear. This ...

Last Updated: 23 Jul 2015

Go To URL
Helicobacter pylori eradication in gastric diffuse large B cell lymphoma.
 

Author(s): Semra Paydas

Journal: World J. Gastroenterol.. 2015 Apr;21(13):3773-6.

 

Diffuse large B cell lymphoma (DLBCL) of the stomach is a heterogenous disease. There are tumors without histological evidence of mucosa-associated lymphoid tissue (MALT) lymphoma, which are classified as pure or de novo DLBCL and those with evidence of MALT, which are classified ...

Last Updated: 8 Apr 2015

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Study in Patients With Primary Breast Diffuse Large B-cell Lymphoma
 

Status: Recruiting

Condition Summary: Large B Cell Diffuse Lymphoma

 

Last Updated: 5 Feb 2016

Go to URL
FLT-PET/CT vs FDG-PET/CT for Therapy Monitoring of Diffuse Large B-cell Lymphoma
 

Status: Recruiting

Condition Summary: Lymphoma; Lymphoma, Non-Hodgkin; Large B Cell Diffuse Lymphoma

 

Last Updated: 14 Feb 2014

Go to URL
ACP-196, a Btk Inhibitor, for Treatment of de Novo Activated B-cell (ABC) Subtype of Diffuse Large B-Cell Lymphoma
 

Status: Recruiting

Condition Summary: Activated B-cell Diffuse Large B-Cell Lymphoma (ABC DLBCL)

 

Last Updated: 5 Nov 2015

Go to URL