Lactic Acidosis

Common Name(s)

Lactic Acidosis

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lactic Acidosis" for support, advocacy or research.

United Mitochondrial Disease Foundation

The United Mitochondrial Disease Foundation strives to promote research and education for the diagnosis, treatment and cures of mitochondrial disorders and to provide support to affected individuals and families.

Last Updated: 28 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lactic Acidosis" for support, advocacy or research.

United Mitochondrial Disease Foundation

The United Mitochondrial Disease Foundation strives to promote research and education for the diagnosis, treatment and cures of mitochondrial disorders and to provide support to affected individuals and families.

http://www.umdf.org

Last Updated: 28 Feb 2013

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lactic Acidosis" returned 262 free, full-text research articles on human participants. First 3 results:

Phenotypic variability and identification of novel YARS2 mutations in YARS2 mitochondrial myopathy, lactic acidosis and sideroblastic anaemia.
 

Author(s): Lisa G Riley, Minal J Menezes, Joƫlle Rudinger-Thirion, Rachael Duff, Pascale de Lonlay, Agnes Rotig, Michel C Tchan, Mark Davis, Sandra T Cooper, John Christodoulou

Journal:

 

Mutations in the mitochondrial tyrosyl-tRNA synthetase (YARS2) gene have previously been identified as a cause of the tissue specific mitochondrial respiratory chain (RC) disorder, Myopathy, Lactic Acidosis, Sideroblastic Anaemia (MLASA). In this study, a cohort of patients with a ...

Last Updated: 20 Dec 2013

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Severe lactic acidosis and acute pancreatitis associated with cimetidine in a patient with type 2 diabetes mellitus taking metformin.
 

Author(s): Ji Ho Seo, Da Young Lee, Chang Woo Hong, In Hee Lee, Ki Sung Ahn, Gun Woo Kang

Journal: Intern. Med.. 2013 ;52(19):2245-8.

 

An 82-year-old woman with type 2 diabetes mellitus, hypertension, and unstable angina presented with severe lactic acidosis and acute kidney injury (AKI) accompanied by acute pancreatitis. Her medical history revealed that she had taken cimetidine for two weeks while taking other ...

Last Updated: 3 Oct 2013

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A homozygous mutation in LYRM7/MZM1L associated with early onset encephalopathy, lactic acidosis, and severe reduction of mitochondrial complex III activity.
 

Author(s): Federica Invernizzi, Marco Tigano, Cristina Dallabona, Claudia Donnini, Ileana Ferrero, Maurizio Cremonte, Daniele Ghezzi, Costanza Lamperti, Massimo Zeviani

Journal: Hum. Mutat.. 2013 Dec;34(12):1619-22.

 

Mutations in nuclear genes associated with defective complex III (cIII) of the mitochondrial respiratory chain are rare, having been found in only two cIII assembly factors and, as private changes in single families, three cIII structural subunits. Recently, human LYRM7/MZM1L, the ...

Last Updated: 14 Nov 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lactic Acidosis" returned 20 free, full-text review articles on human participants. First 3 results:

Lactic acidosis during telbivudine treatment for HBV: a case report and literature review.
 

Author(s): Jia-Lin Jin, Piao Hu, Jia-Hong Lu, Su-Shan Luo, Xiao-Yun Huang, Xin-Hua Weng, Ji-Ming Zhang

Journal: World J. Gastroenterol.. 2013 Sep;19(33):5575-80.

 

All oral nucleoside analogues against hepatitis B virus, with an exception of telbivudine, have been reported causing lactic acidosis (LA). Here we report the first case of chronic hepatitis B developing severe refractory LA during telbivudine monotherapy. A 36-year-old man of Chinese ...

Last Updated: 11 Sep 2013

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Metformin-associated lactic acidosis requiring hospitalization. A national 10 year survey and a systematic literature review.
 

Author(s): F Renda, P Mura, G Finco, F Ferrazin, L Pani, G Landoni

Journal: Eur Rev Med Pharmacol Sci. 2013 Feb;17 Suppl 1():45-9.

 

Metformin is known to be rarely associated with lactic acidosis, a serious condition with a poor prognosis.

Last Updated: 25 Feb 2013

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Metformin-associated lactic acidosis (MALA): case files of the Einstein Medical Center medical toxicology fellowship.
 

Author(s): Kathryn T Kopec, Michael J Kowalski

Journal: J Med Toxicol. 2013 Mar;9(1):61-6.

 

Last Updated: 20 Feb 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Nitroglycerin Infusion During Cardiac Surgery
 

Status: Recruiting

Condition Summary: Lactic Acidosis; Bleeding

 

Last Updated: 13 Jul 2013

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RBC Transfusion in Severe Anemia With Lactic Acidosis
 

Status: Recruiting

Condition Summary: Anemia

 

Last Updated: 17 Jun 2014

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The Various Effects of Gaseous Albuterol on Serum Lactate
 

Status: Not yet recruiting

Condition Summary: Asthma

 

Last Updated: 29 May 2014

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