Lactic Acidosis

Common Name(s)

Lactic Acidosis

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lactic Acidosis" for support, advocacy or research.

United Mitochondrial Disease Foundation

The United Mitochondrial Disease Foundation strives to promote research and education for the diagnosis, treatment and cures of mitochondrial disorders and to provide support to affected individuals and families.

Last Updated: 28 Jul 2015

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lactic Acidosis" for support, advocacy or research.

United Mitochondrial Disease Foundation

The United Mitochondrial Disease Foundation strives to promote research and education for the diagnosis, treatment and cures of mitochondrial disorders and to provide support to affected individuals and families.

http://www.umdf.org

Last Updated: 28 Jul 2015

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lactic Acidosis" returned 309 free, full-text research articles on human participants. First 3 results:

A Fatal Case of Metformin-associated Lactic Acidosis.
 

Author(s): Toshikazu Ozeki, Rui Kawato, Mitsuru Watanabe, Shun Minatoguchi, Yukari Murai, Akihiro Ryuge, Koji Takasugi, Takuya Hamada, Yukako Oyama, Atsushi Nomura, Tatsuhito Tomino, Hideaki Shimizu, Yoshiro Fujita

Journal: Intern. Med.. 2016 ;55(7):775-8.

 

A 72-year-old woman with a history of type 2 diabetes mellitus was brought to the ER with metformin-associated lactic acidosis. She received continuous hemofiltration and hemodialysis, but the laboratory analyses showed no improvement. She died 11 hours after admission. Metformin ...

Last Updated: 4 Apr 2016

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Lactate Clearance and Vasopressor Seem to Be Predictors for Mortality in Severe Sepsis Patients with Lactic Acidosis Supplementing Sodium Bicarbonate: A Retrospective Analysis.
 

Author(s): Su Mi Lee, Seong Eun Kim, Eun Bin Kim, Hyo Jin Jeong, Young Ki Son, Won Suk An

Journal:

 

Initial lactate level, lactate clearance, C-reactive protein, and procalcitonin in critically ill patients with sepsis are associated with hospital mortality. However, no study has yet discovered which factor is most important for mortality in severe sepsis patients with lactic acidosis. ...

Last Updated: 22 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lactic Acidosis" returned 29 free, full-text review articles on human participants. First 3 results:

Metformin-associated lactic acidosis: Current perspectives on causes and risk.
 

Author(s): Ralph DeFronzo, G Alexander Fleming, Kim Chen, Thomas A Bicsak

Journal: Metab. Clin. Exp.. 2016 Feb;65(2):20-9.

 

Although metformin has become a drug of choice for the treatment of type 2 diabetes mellitus, some patients may not receive it owing to the risk of lactic acidosis. Metformin, along with other drugs in the biguanide class, increases plasma lactate levels in a plasma concentration-dependent ...

Last Updated: 17 Jan 2016

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When should MELAS (Mitochondrial myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like episodes) be the diagnosis?
 

Author(s): Paulo José Lorenzoni, Lineu Cesar Werneck, Cláudia Suemi Kamoi Kay, Carlos Eduardo Soares Silvado, Rosana Herminia Scola

Journal: Arq Neuropsiquiatr. 2015 Nov;73(11):959-67.

 

Mitochondrial myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like episodes (MELAS) is a rare mitochondrial disorder. Diagnostic criteria for MELAS include typical manifestations of the disease: stroke-like episodes, encephalopathy, evidence of mitochondrial dysfunction (laboratorial ...

Last Updated: 31 Oct 2015

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Progress in Diagnosing Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like Episodes.
 

Author(s): Ying-Xin Wang, Wei-Dong Le

Journal: Chin. Med. J.. 2015 Jul;128(13):1820-5.

 

Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) is a progressive, multisystem affected mitochondrial disease associated with a number of disease-related defective genes. MELAS has unpredictable presentations and clinical course, and it can ...

Last Updated: 26 Jun 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Nitroglycerin Infusion During Cardiac Surgery
 

Status: Recruiting

Condition Summary: Lactic Acidosis; Bleeding

 

Last Updated: 13 Jul 2013

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Metformin in Moderate and Severe Renal Failure (CKD 3-4): A Follow-up Study
 

Status: Not yet recruiting

Condition Summary: Renal Insufficiency, Chronic

 

Last Updated: 27 Jul 2016

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Metformin Use in Chronic Kidney Disease: The CKD-Met Study
 

Status: Recruiting

Condition Summary: Type 2 Diabetes; Chronic Kidney Disease

 

Last Updated: 25 Jul 2016

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