Lactic Acidosis

Common Name(s)

Lactic Acidosis

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lactic Acidosis" for support, advocacy or research.

United Mitochondrial Disease Foundation

The United Mitochondrial Disease Foundation strives to promote research and education for the diagnosis, treatment and cures of mitochondrial disorders and to provide support to affected individuals and families.

Last Updated: 28 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lactic Acidosis" for support, advocacy or research.

United Mitochondrial Disease Foundation

The United Mitochondrial Disease Foundation strives to promote research and education for the diagnosis, treatment and cures of mitochondrial disorders and to provide support to affected individuals and families.

http://www.umdf.org

Last Updated: 28 Jul 2015

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lactic Acidosis" returned 309 free, full-text research articles on human participants. First 3 results:

Metformin and lactic acidosis during shock: just the tip of the iceberg?
 

Author(s): Rene A Posma, Anthony R Absalom, Daan J Touw, Iwan C C van der Horst, Maarten W N Nijsten

Journal:

 

Last Updated: 1 Jun 2016

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A Fatal Case of Metformin-associated Lactic Acidosis.
 

Author(s): Toshikazu Ozeki, Rui Kawato, Mitsuru Watanabe, Shun Minatoguchi, Yukari Murai, Akihiro Ryuge, Koji Takasugi, Takuya Hamada, Yukako Oyama, Atsushi Nomura, Tatsuhito Tomino, Hideaki Shimizu, Yoshiro Fujita

Journal: Intern. Med.. 2016 ;55(7):775-8.

 

A 72-year-old woman with a history of type 2 diabetes mellitus was brought to the ER with metformin-associated lactic acidosis. She received continuous hemofiltration and hemodialysis, but the laboratory analyses showed no improvement. She died 11 hours after admission. Metformin ...

Last Updated: 4 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lactic Acidosis" returned 31 free, full-text review articles on human participants. First 3 results:

Metformin-associated lactic acidosis: Current perspectives on causes and risk.
 

Author(s): Ralph DeFronzo, G Alexander Fleming, Kim Chen, Thomas A Bicsak

Journal: Metab. Clin. Exp.. 2016 Feb;65(2):20-9.

 

Although metformin has become a drug of choice for the treatment of type 2 diabetes mellitus, some patients may not receive it owing to the risk of lactic acidosis. Metformin, along with other drugs in the biguanide class, increases plasma lactate levels in a plasma concentration-dependent ...

Last Updated: 17 Jan 2016

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When should MELAS (Mitochondrial myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like episodes) be the diagnosis?
 

Author(s): Paulo José Lorenzoni, Lineu Cesar Werneck, Cláudia Suemi Kamoi Kay, Carlos Eduardo Soares Silvado, Rosana Herminia Scola

Journal: Arq Neuropsiquiatr. 2015 Nov;73(11):959-67.

 

Mitochondrial myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like episodes (MELAS) is a rare mitochondrial disorder. Diagnostic criteria for MELAS include typical manifestations of the disease: stroke-like episodes, encephalopathy, evidence of mitochondrial dysfunction (laboratorial ...

Last Updated: 31 Oct 2015

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Lactic acidosis: Clinical implications and management strategies.
 

Author(s): Anita J Reddy, Simon W Lam, Seth R Bauer, Jorge A Guzman

Journal: Cleve Clin J Med. 2015 Sep;82(9):615-24.

 

In hospitalized patients, elevated serum lactate levels are both a marker of risk and a target of therapy. The authors describe the mechanisms underlying lactate elevations, note the risks associated with lactic acidosis, and outline a strategy for its treatment.

Last Updated: 15 Sep 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Lactate Acidosis in Postoperative Hearts
 

Status: Not yet recruiting

Condition Summary: Post-cardiac Surgery; Hyperlactatemia

 

Last Updated: 17 Jan 2017

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Thiamine vs. Placebo to Increase Oxygen Consumption After Cardiac Arrest
 

Status: Not yet recruiting

Condition Summary: Cardiac Arrest; Shock; Lactic Acidosis; Thiamin Deficiency

 

Last Updated: 28 Nov 2016

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Metformin Use in Chronic Kidney Disease: The CKD-Met Study
 

Status: Recruiting

Condition Summary: Type 2 Diabetes; Chronic Kidney Disease

 

Last Updated: 25 Jul 2016

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