Klippel Trenaunay syndrome

Common Name(s)

Klippel Trenaunay syndrome, Klippel-Trenaunay Syndrome

Klippel Trenaunay syndrome is a condition that affects the development of blood vessels, soft tissues, and bones. This condition has three characteristic features: a red birthmark called a port-wine stain, abnormal overgrowth of soft tissues and bones, and vein malformations. A port-wine stain is a type of birthmark caused by swelling of the small blood vessels near the surface of the skin. The overgrowth of bones and soft tissues usually begins in infancy and is most often limited to one leg. However, overgrowth can also affect the arms or, rarely, the trunk. The abnormal growth can cause pain, a feeling of heaviness, and reduced movement in the affected area. The vein malformations include varicose veins and malformations of deep veins in the limbs. The cause of Klippel-Trenaunay syndrome is unknown. This condition is almost always sporadic, which means that it occurs in people with no history of the disorder in their family.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Klippel Trenaunay syndrome" for support, advocacy or research.

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Klippel-Trenaunay Support Group

The Group's mission is to provide support for K-T Syndrome patients and their families.

Last Updated: 9 Nov 2012

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Klippel Trenaunay syndrome" for support, advocacy or research.

Logo
Klippel-Trenaunay Support Group

The Group's mission is to provide support for K-T Syndrome patients and their families.

http://www.k-t.org

Last Updated: 9 Nov 2012

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Klippel Trenaunay syndrome" returned 106 free, full-text research articles on human participants. First 3 results:

Klippel-Trenaunay-Weber Syndrome with Kasabach-Merritt Coagulopathy and Hydronephrosis.
 

Author(s): Lata Bhat, Supriya Bisht, Kavita Khanijo

Journal: Indian Pediatr. 2015 Nov;52(11):987-8.

 

Klippel-Trenaunay-Weber Syndrome is a rare syndrome, consisting of vascular malformation of blood and lymph vessels.

Last Updated: 30 Nov 2015

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Sciatic nerve hypertrophy with Klippel-Trenaunay syndrome: a case report.
 

Author(s): Ilker Ilhanli, Ozlem Keskin, Erhan Arslan, Mehmet Ekiz

Journal: Turk Neurosurg. 2015 ;25(3):500-2.

 

A 73-year-old female patient who had severe neuropathic pain due to sciatic nerve hypertrophy with the Klippel-Trenaunay Syndrome has been presented. Localized hypertrophic neuropathy is in one region and characterized by concentric proliferation of Schwann cells around the axon. ...

Last Updated: 3 Jun 2015

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Glioblastoma multiforme in Klippel-Trenaunay-Weber syndrome: a case report.
 

Author(s): Tevfik Yilmaz, Ulas Cikla, Alice Kirst, Mustafa K Baskaya

Journal:

 

Klippel-Trenaunay-Weber syndrome (KTWS) is a rare syndrome in which patients usually present with cutaneous hemangiomas, venous varicosities, and bone and soft tissue hypertrophy of the affected limb. Intracranial lesions in patients with KTWS are extremely rare, and are generally ...

Last Updated: 1 May 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Klippel Trenaunay syndrome" returned 11 free, full-text review articles on human participants. First 3 results:

Ophthalmic Alterations in the Sturge-Weber Syndrome, Klippel-Trenaunay Syndrome, and the Phakomatosis Pigmentovascularis: An Independent Group of Conditions?
 

Author(s): Solmaz Abdolrahimzadeh, Vittorio Scavella, Lorenzo Felli, Filippo Cruciani, Maria Teresa Contestabile, Santi Maria Recupero

Journal: Biomed Res Int. 2015 ;2015():786519.

 

The phakomatoses have been traditionally defined as a group of hereditary diseases with variable expressivity characterized by multisystem tumors with possible malignant transformation. The Sturge-Weber syndrome, Klippel-Trenaunay syndrome, and the phakomatosis pigmentovascularis ...

Last Updated: 9 Oct 2015

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[Klippel-Trenaunay syndrome and pregnancy: difficult choice of delivery from a case and a review of the literature].
 

Author(s): A Koch, G Aïssi, A Gaudineau, N Sananes, R Murtada, R Favre, I Nisand

Journal: J Gynecol Obstet Biol Reprod (Paris). 2014 Sep;43(7):483-7.

 

Klippel-Trenaunay syndrome (SKT) is a rare disease characterized by cutaneous haemangiomas, capillary malformations venous (venous varicosities), bone and soft tissue hypertrophy affecting one or more limbs. It is often associated with hemorrhagic and thrombotic complications, especially ...

Last Updated: 6 Aug 2014

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Conus medullaris-cauda arteriovenous malformation and Klippel-Trenaunay syndrome: what is the treatment goal?
 

Author(s): Donatella Sgubin, Ryuichi Kanai, Francesco Di Paola, Alessandro Perin, Pierluigi Longatti

Journal: Neurol. Med. Chir. (Tokyo). 2013 ;53(2):110-4.

 

A 29-year-old man with Klippel-Trenaunay syndrome (KTS) presented with a symptomatic conus medullaris-cauda arteriovenous malformation (AVM) manifesting as back and right limb pain, which abruptly worsened with the onset of right limb weakness and urinary retention. He was treated ...

Last Updated: 26 Feb 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Innovative Approaches to Gauge Progression of Sturge-Weber Syndrome
 

Status: Recruiting

Condition Summary: Sturge-Weber Syndrome

 

Last Updated: 12 Oct 2015

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Treatment of Port-wine Mark in Sturge-Weber Syndrome Using Topical Timolol
 

Status: Recruiting

Condition Summary: Sturge Weber Syndrome; Port-wine Mark

 

Last Updated: 18 Dec 2015

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Lymphatic Anomalies Registry
 

Status: Recruiting

Condition Summary: Lymphatic Malformation; Generalized Lymphatic Anomaly (GLA); Central Conducting Lymphatic Anomaly; CLOVES Syndrome; Gorham-Stout Disease ("Disappearing Bone Disease"); Blue Rubber Bleb Nevus Syndrome; Kaposiform Lymphangiomatosis; Kaposiform Hemangioendothelioma/Tufted Angioma; Klippel-Trenaunay Syndrome; Lymphangiomatosis

 

Last Updated: 4 Nov 2015

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