Klebsiella

Common Name(s)

Klebsiella

Klebsiella infections refer to several different types of healthcare-associated infections that are all caused by the Klebsiella bacteria, including pneumonia; bloodstream infections; wound or surgical site infections; and meningitis. Healthy people usually do not get Klebsiella infections. However, people who are hospitalized and receiving treatment for other conditions may be susceptible to these infections. In healthcare settings, people who require long courses of antibiotics and/or devices such as ventilators (breathing machines) or intravenous (vein) catheters are at the most risk for Klebsiella infections. These infections are often treated with antibiotics, although some Klebsiella bacteria may be resistant to certain types of antibiotics.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Klebsiella" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Klebsiella" returned 1688 free, full-text research articles on human participants. First 3 results:

[Investigation of plasmid-mediated quinolone resistance genes in quinolone-resistant Escherichia coli and Klebsiella spp. isolates from bloodstream infections].
 

Author(s): Celal Kurtuluş Buruk, Hikmet Öztel Ocak, Gülçin Bayramoğlu, Faruk Aydın

Journal: Mikrobiyol Bul. 2016 Apr;50(2):186-95.

 

One of the treatment options of Escherichia coli and Klebsiella spp. infections which are the most common opportunistic pathogens of gram-negative sepsis is quinolones. Resistance to quinolones which act by disrupting DNA synthesis has been increasing. Horizontal transfer of plasmid-mediated ...

Last Updated: 14 May 2016

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[Investigation of carbapenemases in carbapenem-resistant Escherichia coli and Klebsiella pneumoniae strains isolated in 2014 in Turkey].
 

Author(s): Aslı Çakar, Yakut Akyön, Deniz Gür, Onur Karatuna, Dilara Öğünç, Betil Özhak Baysan, Nilay Çöplü, Mustafa Çağatay, Abdullah Kılıç, Mehmet Baysallar, Zahir Bakıcı, Cem Çelik, Zeynep Gülay, Şöhret Aydemir, Alper Tünger, Hüseyin Kılıç, Barış Derya Erçal, Zulal Aşçı Toraman, Yasemin Zer, Ayşe Büyüktaş, Selma Ay, Zerrin Aktaş, Çiğdem Kayacan, Gülçin Bayramoğlu, Faruk Aydın, Devrim Dündar, Ufuk Hasdemir, Ramazan Ayaş, Keramettin Yanık, Murat Günaydın, Hüseyin Güdücüoğlu, Mehmet Parlak

Journal: Mikrobiyol Bul. 2016 Jan;50(1):21-33.

 

Carbapenems are the choice of treatment in infections caused by multidrug resistant Enterobacteriaceae. In recent years carbapenem-resistant Enterobacteriaceae isolates due to carbapenemases have been increasingly reported worldwide. Multicenter studies on carbapenemases are scarce ...

Last Updated: 9 Apr 2016

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Whole genome sequence of Klebsiella pneumoniae U25, a hypermucoviscous, multidrug resistant, biofilm producing isolate from India.
 

Author(s): Zumaana Rafiq, Nithin Sam, Rama Vaidyanathan

Journal: Mem. Inst. Oswaldo Cruz. 2016 Feb;111(2):144-6.

 

Klebsiella pneumoniae U25 is a multidrug resistant strain isolated from a tertiary care hospital in Chennai, India. Here, we report the complete annotated genome sequence of strain U25 obtained using PacBio RSII. This is the first report of the whole genome of K. pneumoniaespecies ...

Last Updated: 13 Feb 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Klebsiella" returned 27 free, full-text review articles on human participants. First 3 results:

Clinical and Molecular Epidemiology of Extended-Spectrum Beta-Lactamase-Producing Klebsiella spp.: A Systematic Review and Meta-Analyses.
 

Author(s): Tirza C Hendrik, Anne F Voor In 't Holt, Margreet C Vos

Journal:

 

Healthcare-related infections caused by extended-spectrum beta-lactamase (ESBL)-producing Klebsiella spp. are of major concern. To control transmission, deep understanding of the transmission mechanisms is needed. This systematic review aimed to identify risk factors and sources, ...

Last Updated: 21 Oct 2015

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Lemierre's Syndrome Caused by Klebsiella pneumoniae in a Diabetic Patient: A Case Report and Review of the Literature.
 

Author(s): Alan Chuncharunee, Thana Khawcharoenporn

Journal: Hawaii J Med Public Health. 2015 Aug;74(8):260-6.

 

Lemierre's syndrome is characterized by an oropharyngeal infection with internal jugular vein thrombosis followed by metastatic infections in other organs. This infection is usually caused by Fusobacterium spp. In this report, we present a rare case of Klebsiella pneumoniae-associated ...

Last Updated: 17 Aug 2015

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Carbapenemase-Producing Klebsiella pneumoniae, a Key Pathogen Set for Global Nosocomial Dominance.
 

Author(s): Johann D D Pitout, Patrice Nordmann, Laurent Poirel

Journal: Antimicrob. Agents Chemother.. 2015 Oct;59(10):5873-84.

 

The management of infections due to Klebsiella pneumoniae has been complicated by the emergence of antimicrobial resistance, especially to carbapenems. Resistance to carbapenems in K. pneumoniae involves multiple mechanisms, including the production of carbapenemases (e.g., KPC, NDM, ...

Last Updated: 19 Sep 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Probiotics for Eradication of Carbapenem Resistant Klebsiella Pneumonia
 

Status: Not yet recruiting

Condition Summary: Anti-Biotic Resistance; Klebsiella Pneumoniae

 

Last Updated: 24 Jul 2008

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SDD for Eradicating CRKP Carriage
 

Status: Not yet recruiting

Condition Summary: Carriers of Carbapenem-resistant Klebsiella Pneumonia

 

Last Updated: 3 Jan 2013

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Sitafloxacin and Ertapenem Treatment for Acute Urinary Tract Infection Caused by E. Coli or K. Pneumoniae in Post-kidney Transplantation Patients
 

Status: Recruiting

Condition Summary: Anti-Infective Agents, Urinary; Escherichia Coli Infections; Klebsiella Infections; Kidney Transplantation; Urinary Tract Infections

 

Last Updated: 31 Mar 2016

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