Klebsiella

Common Name(s)

Klebsiella

Klebsiella infections refer to several different types of healthcare-associated infections that are all caused by the Klebsiella bacteria, including pneumonia; bloodstream infections; wound or surgical site infections; and meningitis. Healthy people usually do not get Klebsiella infections. However, people who are hospitalized and receiving treatment for other conditions may be susceptible to these infections. In healthcare settings, people who require long courses of antibiotics and/or devices such as ventilators (breathing machines) or intravenous (vein) catheters are at the most risk for Klebsiella infections. These infections are often treated with antibiotics, although some Klebsiella bacteria may be resistant to certain types of antibiotics.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Klebsiella" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Klebsiella" returned 1650 free, full-text research articles on human participants. First 3 results:

Deciphering tissue-induced Klebsiella pneumoniae lipid A structure.
 

Author(s): Enrique Llobet, Verónica Martínez-Moliner, David Moranta, Käthe M Dahlström, Verónica Regueiro, Anna Tomás, Victoria Cano, Camino Pérez-Gutiérrez, Christian G Frank, Helena Fernández-Carrasco, José Luis Insua, Tiina A Salminen, Junkal Garmendia, José A Bengoechea

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2015 Nov;112(46):E6369-78.

 

The outcome of an infection depends on host recognition of the pathogen, hence leading to the activation of signaling pathways controlling defense responses. A long-held belief is that the modification of the lipid A moiety of the lipopolysaccharide could help Gram-negative pathogens ...

Last Updated: 20 Nov 2015

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Molecular epidemiology of carbapenem resistant Enterobacteriaceae in Valle d'Aosta region, Italy, shows the emergence of KPC-2 producing Klebsiella pneumoniae clonal complex 101 (ST101 and ST1789).
 

Author(s): Mariateresa Del Franco, Laura Paone, Roberto Novati, Claudio G Giacomazzi, Maria Bagattini, Chiara Galotto, Pier Giorgio Montanera, Maria Triassi, Raffaele Zarrilli

Journal:

 

The spread of carbapenem resistant Enterobacteriaceae (CRE) is an emerging clinical problem, of great relevance in Europe and worldwide. The aim of this study was the molecular epidemiology of CRE isolates in Valle d'Aosta region, Italy, and the mechanism of carbapenem resistance.

Last Updated: 10 Nov 2015

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The spread of bla OXA-48 and bla OXA-244 carbapenemase genes among Klebsiella pneumoniae, Proteus mirabilis and Enterobacter spp. isolated in Moscow, Russia.
 

Author(s): Nadezhda K Fursova, Eugeny I Astashkin, Anastasia I Knyazeva, Nikolay N Kartsev, Ekaterina S Leonova, Olga N Ershova, Irina A Alexandrova, Natalia V Kurdyumova, Svetlana Yu Sazikina, Nikolay V Volozhantsev, Edward A Svetoch, Ivan A Dyatlov

Journal:

 

The spread of carbapenemase-producing Enterobacteriaceae (CPE) is a great problem of healthcare worldwide. Study of the spread for bla OXA-48-like genes coding epidemically significant carbapenemases among hospital pathogens is important for the regional and global epidemiology of ...

Last Updated: 3 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Klebsiella" returned 25 free, full-text review articles on human participants. First 3 results:

Lemierre's Syndrome Caused by Klebsiella pneumoniae in a Diabetic Patient: A Case Report and Review of the Literature.
 

Author(s): Alan Chuncharunee, Thana Khawcharoenporn

Journal: Hawaii J Med Public Health. 2015 Aug;74(8):260-6.

 

Lemierre's syndrome is characterized by an oropharyngeal infection with internal jugular vein thrombosis followed by metastatic infections in other organs. This infection is usually caused by Fusobacterium spp. In this report, we present a rare case of Klebsiella pneumoniae-associated ...

Last Updated: 17 Aug 2015

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Klebsiella pneumoniae bloodstream infection: epidemiology and impact of inappropriate empirical therapy.
 

Author(s): Nicolò Girometti, Russell E Lewis, Maddalena Giannella, Simone Ambretti, Michele Bartoletti, Sara Tedeschi, Fabio Tumietto, Francesco Cristini, Filippo Trapani, Paolo Gaibani, Pierluigi Viale

Journal: Medicine (Baltimore). 2014 Oct;93(17):298-309.

 

Multidrug resistance associated with extended-spectrum beta-lactamase (ESBL) and Klebsiella pneumoniae carbapenemase (KPC) among K. pneumoniae is endemic in southern Europe. We retrospectively analyzed the impact of resistance on the appropriateness of empirical therapy and treatment ...

Last Updated: 15 Nov 2014

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Carbapenemase-producing Klebsiella pneumoniae: molecular and genetic decoding.
 

Author(s): Liang Chen, Barun Mathema, Kalyan D Chavda, Frank R DeLeo, Robert A Bonomo, Barry N Kreiswirth

Journal: Trends Microbiol.. 2014 Dec;22(12):686-96.

 

Klebsiella pneumoniae carbapenemases (KPCs) were first identified in 1996 in the USA. Since then, regional outbreaks of KPC-producing K. pneumoniae (KPC-Kp) have occurred in the USA, and have spread internationally. Dissemination of blaKPC involves both horizontal transfer of blaKPC ...

Last Updated: 3 Dec 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Probiotics for Eradication of Carbapenem Resistant Klebsiella Pneumonia
 

Status: Not yet recruiting

Condition Summary: Anti-Biotic Resistance; Klebsiella Pneumoniae

 

Last Updated: 24 Jul 2008

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SDD for Eradicating CRKP Carriage
 

Status: Not yet recruiting

Condition Summary: Carriers of Carbapenem-resistant Klebsiella Pneumonia

 

Last Updated: 3 Jan 2013

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Sitafloxacin and Ertapenem Treatment for Acute Urinary Tract Infection Caused by E. Coli or K. Pneumoniae in Post-kidney Transplantation Patients
 

Status: Recruiting

Condition Summary: Anti-Infective Agents, Urinary; Escherichia Coli Infections; Klebsiella Infections; Kidney Transplantation; Urinary Tract Infections

 

Last Updated: 31 Mar 2016

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