Kikuchi disease

Common Name(s)

Kikuchi disease

Kikuchi disease is a benign (non-cancerous) condition of the lymph nodes. It is usually characterized by cervical lymphadenopathy (tender, swollen lymph nodes), mild fever, and night sweats. Less common symptoms include weight loss, nausea, vomiting, and sore throat. While the exact cause of this condition has not been proven, infectious and autoimmune causes have been suggested, such as an immune response to a viral infection. Treatment is symptomatic and supportive and may include pain relievers or non-steroidal anti-inflammatory drugs (NSAIDS), and corticosteroids in rare cases. Most cases go away on their own within 1 to 6 months.
 

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Condition Specific Organizations

Following organizations serve the condition "Kikuchi disease" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Kikuchi disease" returned 63 free, full-text research articles on human participants. First 3 results:

[Kikuchi-Fujimoto disease: about a case].
 

Author(s): Sanaa Elfihri, Mustapha Laine, Fouad Kettani, Jaouda Ben Amor, Jamel Eddine Bourkadi

Journal:

 

Kikuchi-Fujimoto disease or histiocytic necrotizing lymphadenitis is a rare cause of benign cervical adenopathies. It is an anatomoclinic entity of unknown cause. Diagnosis is based on histologic examination of the lymph nodes. Patient's evolution is generally favorable with spontaneous ...

Last Updated: 14 Sep 2017

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CT pattern analysis of necrotizing and nonnecrotizing lymph nodes in Kikuchi disease.
 

Author(s): Eun Jung Shim, Kyung Mi Lee, Eui Jong Kim, Hyug-Gi Kim, Ji Hye Jang

Journal:

 

The purpose of this study was to determine whether a CT interpretation with imaging pattern analysis differentiates Kikuchi disease (KD) from the two more frequently encountered differential lymph nodes diagnoses of tuberculous lymphadenopathy (TL) and reactive hyperplasia (RH).

Last Updated: 25 Jul 2017

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The incidence and clinical characteristics by gender differences in patients with Kikuchi-Fujimoto disease.
 

Author(s): In Young Jung, Hea Won Ann, Jung Ju Kim, Se Ju Lee, Jinnam Kim, Hye Seong, Dong Hyun Oh, Yong Chan Kim, Eun Jin Kim, Su Jin Jeong, Nam Su Ku, Jun Yong Choi, Young Goo Song, June Myung Kim

Journal: Medicine (Baltimore). 2017 Mar;96(11):e6332.

 

Kikuchi-Fujimoto disease (KFD) is a rare, self-limiting disorder that typically affects the cervical lymph nodes (LNs). Although initially described in young women, KFD also occurs in men. There are no reports on the clinical manifestations and characteristics of male KFD patients. ...

Last Updated: 15 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Kikuchi disease" returned 13 free, full-text review articles on human participants. First 3 results:

Histiocytic necrotising lymphadenitis in mediastinum mimicking thymoma or lymphoma - case presentation and literature review of Kikuchi Fujimoto disease.
 

Author(s): P Błasiak, M Jeleń, A Rzechonek, M Marciniak, K Pawełczyk, J Cianciara, J Kołodziej, B Muszczyńska-Bernhard

Journal: Pol J Pathol. 2016 Mar;67(1):91-5; quiz 96.

 

Kikuchi Fujimoto disease (KFD) as a rare self-limiting lymphadenopathy of short and benign course concerns most frequently the lymph nodes of the neck. The most common symptoms are painfulness of the diseased area, fever and night sweating. The etiology is not well understood, but ...

Last Updated: 15 May 2016

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An uncommon presentation of Kikuchi Fujimoto disease: a case report with literature review.
 

Author(s): Sabin Ranabhat, Mamta Tiwari, Jiwan Kshetri, Sushna Maharjan, Bidur Prasad Osti

Journal:

 

Kikuchi-Fujimoto disease is so named because Kikuchi and Fujimoto were the first scientists to describe it in Japan in 1972. Although the disease has been reported from all over the world and more so from Asia, it is rare. To date only eight cases have been reported from Nepal. Cervical ...

Last Updated: 28 Sep 2015

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Kikuchi-Fujimoto disease: retrospective study of 91 cases and review of the literature.
 

Author(s): Guillaume Dumas, Virginie Prendki, Julien Haroche, Zahir Amoura, Patrice Cacoub, Lionel Galicier, Olivier Meyer, Christophe Rapp, Christophe Deligny, Bertrand Godeau, Elisabeth Aslangul, Olivier Lambotte, Thomas Papo, Jacques Pouchot, Mohamed Hamidou, Claude Bachmeyer, Eric Hachulla, Thierry Carmoi, Robin Dhote, Magdalena Gerin, Arsene Mekinian, Jérôme Stirnemann, Fréderic Charlotte, Dominique Farge, Thierry Molina, Olivier Fain

Journal: Medicine (Baltimore). 2014 Nov;93(24):372-82.

 

Kikuchi-Fujimoto disease (KFD) is a rare cause of lymphadenopathy, most often cervical. It has been mainly described in Asia. There are few data available on this disease in Europe. We conducted this retrospective, observational, multicenter study to describe KFD in France and to ...

Last Updated: 16 Dec 2014

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.