Kikuchi disease

Common Name(s)

Kikuchi disease

Kikuchi disease is a benign (non-cancerous) condition of the lymph nodes. It is usually characterized by cervical lymphadenopathy (tender, swollen lymph nodes), mild fever, and night sweats. Less common symptoms include weight loss, nausea, vomiting, and sore throat. While the exact cause of this condition has not been proven, infectious and autoimmune causes have been suggested, such as an immune response to a viral infection. Treatment is symptomatic and supportive and may include pain relievers or non-steroidal anti-inflammatory drugs (NSAIDS), and corticosteroids in rare cases. Most cases go away on their own within 1 to 6 months.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Kikuchi disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Kikuchi disease" returned 44 free, full-text research articles on human participants. First 3 results:

Diagnosis of Kikuchi-Fujimoto disease: a comparison between open biopsy and minimally invasive ultrasound-guided core biopsy.
 

Author(s): Shan-Chi Yu, Chun-Nan Chen, Hsin-I Huang, Tseng-Cheng Chen, Cheng-Ping Wang, Pei-Jen Lou, Jenq-Yuh Ko, Tzu-Yu Hsiao, Tsung-Lin Yang

Journal:

 

Kikuchi-Fujimoto disease (KFD) is a self-limited disease without any need of surgical treatments. Sampling of tissue is the only invasive procedure during the clinical course. However, the standard sampling procedure with accuracy, minimal invasiveness, and esthetic maintenance has ...

Last Updated: 5 May 2014

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Kikuchi-Fujimoto's disease: a case series from Sri Lanka.
 

Author(s): R A Abeysekara, S A M Kularatne, R Waduge, A G W Sandeepana, J M R P Bandara, I V B Imbulpitiya

Journal: Ceylon Med J. 2013 Mar;58(1):31-3.

 

Kikuchi's disease is a rare, benign, self-limiting disease, mainly involving the lymph nodes of young people. The etiology is unknown. Clinical symptoms and basic investigations may mimic lymphomas and chronic granulomatous conditions like tuberculosis. Lymph node biopsy shows characteristic ...

Last Updated: 3 Apr 2013

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Kikuchi--Fujimoto disease: a rare presentation of a groin lump.
 

Author(s): Shayan Shah, Ananth Vijendren, Marion Obichere

Journal:

 

Lumps in the groin frequently present to the accident and emergency department and can relate to a number of diseases that require different management. Kikuchi's disease, first described in Japan in 1972 is a form of histiocytic necrotising lymphadenitis. It was discovered as a result ...

Last Updated: 19 Feb 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Kikuchi disease" returned 13 free, full-text review articles on human participants. First 3 results:

Pathogenesis, diagnosis, and management of Kikuchi-Fujimoto disease.
 

Author(s): Darcie Deaver, Pedro Horna, Hernani Cualing, Lubomir Sokol

Journal: Cancer Control. 2014 Oct;21(4):313-21.

 

Kikuchi-Fujimoto disease (KFD) is a rare lymphohistiocytic disorder with an unknown etiopathogenesis. This disease is misdiagnosed as malignant lymphoma in up to one-third of cases and is associated with the development of systemic lupus erythematosus (SLE).

Last Updated: 14 Oct 2014

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Kikuchi-Fujimoto disease as a rare cause of lymphadenopathy--two cases report and review of current literature.
 

Author(s): Katarzyna Mrówka-Kata, Dariusz Kata, Sławomira Kyrcz-Krzemień, Paweł Sowa

Journal: Otolaryngol Pol. ;67(1):1-5.

 

Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a benign and self-limited disease, characterized typically by enlargement of regional lymph nodes accompanied by fever. KFD affects predominantly young adult females of Asian origin and is rarely ...

Last Updated: 4 Feb 2013

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Recurrent aseptic meningitis in association with Kikuchi-Fujimoto disease: case report and literature review.
 

Author(s): Tomoko Komagamine, Takahide Nagashima, Masaru Kojima, Norito Kokubun, Toshiki Nakamura, Kenich Hashimoto, Kazuhito Kimoto, Koichi Hirata

Journal:

 

Kikuchi Fujimoto disease (KFD), or histiocytic necrotising lymphadenitis, is a benign and self-limiting condition characterised by primarily affecting the cervical lymph nodes. Recurrent aseptic meningitis in association with KFD is extremely rare and remains a diagnostic challenge.

Last Updated: 13 Feb 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 31 Jan 2012

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