Kikuchi disease

Common Name(s)

Kikuchi disease

Kikuchi disease is a benign (non-cancerous) condition of the lymph nodes. It is usually characterized by cervical lymphadenopathy (tender, swollen lymph nodes), mild fever, and night sweats. Less common symptoms include weight loss, nausea, vomiting, and sore throat. While the exact cause of this condition has not been proven, infectious and autoimmune causes have been suggested, such as an immune response to a viral infection. Treatment is symptomatic and supportive and may include pain relievers or non-steroidal anti-inflammatory drugs (NSAIDS), and corticosteroids in rare cases. Most cases go away on their own within 1 to 6 months.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Kikuchi disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Kikuchi disease" returned 57 free, full-text research articles on human participants. First 3 results:

Kikuchi Disease-Like Inflammatory Pattern in Cutaneous Inflammatory Infiltrates Without Lymph Node Involvement: A New Clue for the Diagnosis of Lupus?
 

Author(s): Lan-Huong Thai, Saskia Ingen-Housz-Oro, Bertrand Godeau, Luc Rethers, Pierre Wolkenstein, Nicolas Limal, Virginie Papillon, Jean Kapfer, Olivier Chosidow, Nicolas Ortonne

Journal: Medicine (Baltimore). 2015 Nov;94(46):e2065.

 

Kikuchi-Fujimoto disease (KFD) is a rare and benign disorder that usually occurs in young adults with enlarged lymph nodes containing infiltrate of cytotoxic T cells and nuclear debris. It can be a manifestation of systemic lupus erythematosus (SLE) although the strength of this association ...

Last Updated: 20 Nov 2015

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Comparison of Ultrasonographic Findings of Biopsy-Proven Tuberculous Lymphadenitis and Kikuchi Disease.
 

Author(s): Inseon Ryoo, Sangil Suh, Young Hen Lee, Hyung Suk Seo, Hae Young Seol

Journal: Korean J Radiol. ;16(4):767-75.

 

Although tuberculous lymphadenitis and Kikuchi disease are common causes of cervical lymphadenopathy in Asians and exhibit similar clinical manifestations, their treatment strategies are totally different. The purpose of this study was to identify ultrasonographic features that distinguish ...

Last Updated: 16 Jul 2015

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Real-time elastography of cervical lymph nodes in Kikuchi disease.
 

Author(s): Kwang Hwi Lee, JiHwa Ryu

Journal: J Ultrasound Med. 2014 Dec;33(12):2201-5.

 

We report, to our knowledge, the first cases of sonographic and real-time elastographic findings of cervical lymph nodes in patients with Kikuchi disease. Cervical lymph nodes had probably benign findings on grayscale sonography and real-time elastography.

Last Updated: 26 Nov 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Kikuchi disease" returned 14 free, full-text review articles on human participants. First 3 results:

Kikuchi-Fujimoto disease: retrospective study of 91 cases and review of the literature.
 

Author(s): Guillaume Dumas, Virginie Prendki, Julien Haroche, Zahir Amoura, Patrice Cacoub, Lionel Galicier, Olivier Meyer, Christophe Rapp, Christophe Deligny, Bertrand Godeau, Elisabeth Aslangul, Olivier Lambotte, Thomas Papo, Jacques Pouchot, Mohamed Hamidou, Claude Bachmeyer, Eric Hachulla, Thierry Carmoi, Robin Dhote, Magdalena Gerin, Arsene Mekinian, Jérôme Stirnemann, Fréderic Charlotte, Dominique Farge, Thierry Molina, Olivier Fain

Journal: Medicine (Baltimore). 2014 Nov;93(24):372-82.

 

Kikuchi-Fujimoto disease (KFD) is a rare cause of lymphadenopathy, most often cervical. It has been mainly described in Asia. There are few data available on this disease in Europe. We conducted this retrospective, observational, multicenter study to describe KFD in France and to ...

Last Updated: 16 Dec 2014

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Pathogenesis, diagnosis, and management of Kikuchi-Fujimoto disease.
 

Author(s): Darcie Deaver, Pedro Horna, Hernani Cualing, Lubomir Sokol

Journal: Cancer Control. 2014 Oct;21(4):313-21.

 

Kikuchi-Fujimoto disease (KFD) is a rare lymphohistiocytic disorder with an unknown etiopathogenesis. This disease is misdiagnosed as malignant lymphoma in up to one-third of cases and is associated with the development of systemic lupus erythematosus (SLE).

Last Updated: 14 Oct 2014

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Kikuchi-Fujimoto disease: report of 4 cases and review of the literature.
 

Author(s): L Lamzaf, H Harmouche, M Maamar, M Adnaoui, M Aouni, Z Tazi Mezalek

Journal: Eur Ann Otorhinolaryngol Head Neck Dis. 2014 Dec;131(6):329-32.

 

Kikuchi-Fujimoto disease or histiocytic necrotizing lymphadenitis is a benign disease of unknown origin predominantly affecting young women and presenting in the form of cervical lymphadenopathy and/or prolonged fever.

Last Updated: 1 Dec 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 31 Jan 2012

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