Chronic kidney disease

Common Name(s)

Chronic kidney disease

Chronic kidney disease (CKD), otherwise known as chronic renal failure, occurs when the kidneys become damaged and lose the ability to properly filter out waste from the blood stream. Conditions such as diabetes, high blood pressure, glomerulonephritis, and polycystic kidney disease have all been linked to the development of CKD.

Symptoms of CKD may include fatigue, poor appetite, anemia (low blood count), nausea, swollen feet, irritated skin, increased need to urinate, shortness of breath, high blood pressure, trouble concentrating, and weakening bones. Early stages often do not show symptoms; therefore, regular checkups are critical for elderly and high risk individuals. A diagnosis can be determined through a blood test, urine test, imaging test, or the removal of sample tissue (biopsy).

While CKD can develop in anyone of any age, adults 65 years or older, and those who are African American, Hispanic, Pacific Islander, and American Indian are most at risk. Other risk factors include smoking, obesity, heart disease, high cholesterol, and having a family history of kidney failure.

There are five stages of CKD, each stage representing a gradual loss of function. End stage kidney failure, the fifth stage, is irreversible and fatal, so prevention and immediate intervention is critical. Depending on the cause, CKD can be treated if the source of the complication can be fixed. If this is not the case, treatment options focus on lessening the symptoms and slowing the progression of the disease. If the condition progresses to the point where the kidneys cannot function on their own, treatments may resort to artificial filtering (dialysis) or a kidney transplant. If you or a loved one has been diagnosed with CKD, talk with your doctor about treatment options. Support groups are also good sources of support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic kidney disease" for support, advocacy or research.

Alport Syndrome Foundation

Our MISSION is to educate and support patients and their families that have been affected by this genetic kidney disease with the goal of funding research to find more effective treatment protocols and a cure for Alport Syndrome.

Last Updated: 15 Apr 2014

View Details
American Association of Kidney Patients

Dedicated to improving the quality of life for kidney patients through education, advocacy and fostering patient communities.

Last Updated: 5 May 2014

View Details
Bardet Biedl Syndrome Family Association

Our Mission: Improve the lives of families affected by BBS through information, support and by advancing research and therapy Our Vision: Effective support, therapy, and treatment for all people affected by Bardet Biedl Syndrome

Last Updated: 14 Mar 2013

View Details
Logo
National Kidney Foundation

The National Kidney Foundation, a major voluntary nonprofit health organization, is dedicated to preventing kidney and urinary tract diseases, improving the health and well-being of individuals and families affected by kidney disease and increasing the availability of all organs for transplantation.

Last Updated: 23 Jun 2015

View Details
Logo
The Cain Foundation for Branchio-oto-renal Syndrome (BOR)

The CAIN FOUNDATION, a voluntary based Charity. Our mission is to represent the interests of many people affected by Branchio-oto-renal Syndrome and to improve their quality of life by providing support and information related to this Syndrome. We seek to educate both Medical Practitioners and the public by promoting Branchio-oto-renal (BOR) Syndrome awareness. Vision to Educate. Mission to Care.

Last Updated: 12 Oct 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic kidney disease" for support, advocacy or research.

Alport Syndrome Foundation

Our MISSION is to educate and support patients and their families that have been affected by this genetic kidney disease with the goal of funding research to find more effective treatment protocols and a cure for Alport Syndrome.

http://www.alportsyndrome.org

Last Updated: 15 Apr 2014

View Details
American Association of Kidney Patients

Dedicated to improving the quality of life for kidney patients through education, advocacy and fostering patient communities.

http://www.aakp.org

Last Updated: 5 May 2014

View Details
Bardet Biedl Syndrome Family Association

Our Mission: Improve the lives of families affected by BBS through information, support and by advancing research and therapy Our Vision: Effective support, therapy, and treatment for all people affected by Bardet Biedl Syndrome

http://www.bardetbiedl.org/

Last Updated: 14 Mar 2013

View Details
Logo
National Kidney Foundation

The National Kidney Foundation, a major voluntary nonprofit health organization, is dedicated to preventing kidney and urinary tract diseases, improving the health and well-being of individuals and families affected by kidney disease and increasing the availability of all organs for transplantation.

http://www.kidney.org

Last Updated: 23 Jun 2015

View Details
Logo
The Cain Foundation for Branchio-oto-renal Syndrome (BOR)

The CAIN FOUNDATION, a voluntary based Charity. Our mission is to represent the interests of many people affected by Branchio-oto-renal Syndrome and to improve their quality of life by providing support and information related to this Syndrome. We seek to educate both Medical Practitioners and the public by promoting Branchio-oto-renal (BOR) Syndrome awareness. Vision to Educate. Mission to Care.

http://www.thecainfoundation.com

Last Updated: 12 Oct 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic kidney disease" returned 3031 free, full-text research articles on human participants. First 3 results:

Knowledge, attitudes and beliefs of first-degree relatives of patients with chronic kidney disease toward kidney donation in Nigeria.
 

Author(s): Babawale T Bello, Yemi R Raji

Journal: Saudi J Kidney Dis Transpl. 2016 Jan;27(1):118-24.

 

In most parts of Sub-Saharan Africa, kidney transplant programs are dependent on the willingness of relatives of patients with kidney failure to donate kidneys. This study assessed the attitudes of relatives of patients with chronic kidney disease (CKD) toward kidney donation. This ...

Last Updated: 20 Jan 2016

Go To URL
Epidemiology and risk factors of chronic kidney disease in the El-Sharkia Governorate, Egypt.
 

Author(s): Tarek A Ghonemy, Salama E Farag, Sameh A Soliman, Amir El-okely, Yasser El-hendy

Journal: Saudi J Kidney Dis Transpl. 2016 Jan;27(1):111-7.

 

End-stage renal disease (ESRD) is increasing worldwide. Renal replacement therapy and kidney transplantation are increasing the burden on health systems. Various risk factors can lead to this disease. In this work, we tried to study the epidemiology and risk factors of chronic kidney ...

Last Updated: 20 Jan 2016

Go To URL
Risk Factors of Parathyroid Dysfunction in Elderly Patients with Chronic Kidney Disease Undergoing Hemodialysis.
 

Author(s): Weihua Li, Shijun Zhang

Journal: Adv Clin Exp Med. ;24(6):1007-12.

 

Aberrant mineral metabolism and bone diseases, which are commonly seen in chronic kidney disease (CKD), have been considered to be the important causes of morbidity and decreased quality of life.

Last Updated: 16 Jan 2016

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic kidney disease" returned 727 free, full-text review articles on human participants. First 3 results:

Multiple myeloma: Diagnosis and management issues in patients with pre-existing chronic kidney disease.
 

Author(s): Srilatha Vadlamudi, Siva Nagendra Reddy Annapareddy

Journal: Saudi J Kidney Dis Transpl. 2016 Jan;27(1):9-14.

 

Multiple myeloma is one of the most common malignancies encountered in clinical practice. Renal involvement in myeloma is a well-recognized entity. Although rare, another special situation that a nephrologist can encounter is myeloma occurring in a patient with preexisting chronic ...

Last Updated: 20 Jan 2016

Go To URL
Effect of progressive resistive exercise training in improving mobility and functional ability of middle adulthood patients with chronic kidney disease.
 

Author(s): Sanjiv K Sah, Muhammad A Siddiqui, Haider Darain

Journal: Saudi J Kidney Dis Transpl. 2015 Sep;26(5):912-23.

 

Patients with chronic kidney disease (CKD) in their middle adulthood are more prone to reduced mobility than younger patients having the same medical condition. Progressive resistive exercise training (PRT) is deemed an effective treatment approach for the management of muscular weakness ...

Last Updated: 10 Sep 2015

Go To URL
Methodology used in studies reporting chronic kidney disease prevalence: a systematic literature review.
 

Author(s): Katharina Brück, Kitty J Jager, Evangelia Dounousi, Alexander Kainz, Dorothea Nitsch, Johan Ärnlöv, Dietrich Rothenbacher, Gemma Browne, Vincenzo Capuano, Pietro Manuel Ferraro, Jean Ferrieres, Giovanni Gambaro, Idris Guessous, Stein Hallan, Mika Kastarinen, Gerjan Navis, Alfonso Otero Gonzalez, Luigi Palmieri, Solfrid Romundstad, Belinda Spoto, Benedicte Stengel, Charles Tomson, Giovanni Tripepi, Henry Völzke, Andrzej Wiȩcek, Ron Gansevoort, Ben Schöttker, Christoph Wanner, Jose Vinhas, Carmine Zoccali, Wim Van Biesen, Vianda S Stel,

Journal: Nephrol. Dial. Transplant.. 2015 Aug;30 Suppl 4():iv6-16.

 

Many publications report the prevalence of chronic kidney disease (CKD) in the general population. Comparisons across studies are hampered as CKD prevalence estimations are influenced by study population characteristics and laboratory methods.

Last Updated: 25 Jul 2015

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Improving Evidence-Based Primary Care for Chronic Kidney Disease
 

Status: Recruiting

Condition Summary: Chronic Kidney Disease; Chronic Kidney Insufficiency; Chronic Renal Diseases; Chronic Renal Insufficiency; Kidney Insufficiency, Chronic

 

Last Updated: 13 Feb 2014

Go to URL
Primary Cardiovascular Risk Prevention With Aspirin in Chronic Kidney Disease Patients
 

Status: Recruiting

Condition Summary: Chronic Kidney Disease Stage 4; Chronic Kidney Disease Stage 3

 

Last Updated: 17 Oct 2012

Go to URL
The Cost Effectiveness and Evaluation of Disease Management of Chronic Kidney Disease and High Risk Population
 

Status: Recruiting

Condition Summary: Chronic Kidney Diseases; Chronic Kidney Insufficiency

 

Last Updated: 31 Jul 2014

Go to URL