Chronic kidney disease

Common Name(s)

Chronic kidney disease

Chronic kidney disease (CKD), otherwise known as chronic renal failure, occurs when the kidneys become damaged and lose the ability to properly filter out waste from the blood stream. Conditions such as diabetes, high blood pressure, glomerulonephritis, and polycystic kidney disease have all been linked to the development of CKD.

Symptoms of CKD may include fatigue, poor appetite, anemia (low blood count), nausea, swollen feet, irritated skin, increased need to urinate, shortness of breath, high blood pressure, trouble concentrating, and weakening bones. Early stages often do not show symptoms; therefore, regular checkups are critical for elderly and high risk individuals. A diagnosis can be determined through a blood test, urine test, imaging test, or the removal of sample tissue (biopsy).

While CKD can develop in anyone of any age, adults 65 years or older, and those who are African American, Hispanic, Pacific Islander, and American Indian are most at risk. Other risk factors include smoking, obesity, heart disease, high cholesterol, and having a family history of kidney failure.

There are five stages of CKD, each stage representing a gradual loss of function. End stage kidney failure, the fifth stage, is irreversible and fatal, so prevention and immediate intervention is critical. Depending on the cause, CKD can be treated if the source of the complication can be fixed. If this is not the case, treatment options focus on lessening the symptoms and slowing the progression of the disease. If the condition progresses to the point where the kidneys cannot function on their own, treatments may resort to artificial filtering (dialysis) or a kidney transplant. If you or a loved one has been diagnosed with CKD, talk with your doctor about treatment options. Support groups are also good sources of support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic kidney disease" for support, advocacy or research.

Alport Syndrome Foundation

Our MISSION is to educate and support patients and their families that have been affected by this genetic kidney disease with the goal of funding research to find more effective treatment protocols and a cure for Alport Syndrome.

Last Updated: 15 Apr 2014

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American Association of Kidney Patients

Dedicated to improving the quality of life for kidney patients through education, advocacy and fostering patient communities.

Last Updated: 5 May 2014

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Bardet Biedl Syndrome Family Association

Our Mission: Improve the lives of families affected by BBS through information, support and by advancing research and therapy Our Vision: Effective support, therapy, and treatment for all people affected by Bardet Biedl Syndrome

Last Updated: 14 Mar 2013

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National Kidney Foundation

The National Kidney Foundation, a major voluntary nonprofit health organization, is dedicated to preventing kidney and urinary tract diseases, improving the health and well-being of individuals and families affected by kidney disease and increasing the availability of all organs for transplantation.

Last Updated: 23 Jun 2015

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The Cain Foundation for Branchio-oto-renal Syndrome (BOR)

The CAIN FOUNDATION, a voluntary based Charity. Our mission is to represent the interests of many people affected by Branchio-oto-renal Syndrome and to improve their quality of life by providing support and information related to this Syndrome. We seek to educate both Medical Practitioners and the public by promoting Branchio-oto-renal (BOR) Syndrome awareness. Vision to Educate. Mission to Care.

Last Updated: 12 Oct 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic kidney disease" for support, advocacy or research.

Alport Syndrome Foundation

Our MISSION is to educate and support patients and their families that have been affected by this genetic kidney disease with the goal of funding research to find more effective treatment protocols and a cure for Alport Syndrome.

http://www.alportsyndrome.org

Last Updated: 15 Apr 2014

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American Association of Kidney Patients

Dedicated to improving the quality of life for kidney patients through education, advocacy and fostering patient communities.

http://www.aakp.org

Last Updated: 5 May 2014

View Details
Bardet Biedl Syndrome Family Association

Our Mission: Improve the lives of families affected by BBS through information, support and by advancing research and therapy Our Vision: Effective support, therapy, and treatment for all people affected by Bardet Biedl Syndrome

http://www.bardetbiedl.org/

Last Updated: 14 Mar 2013

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National Kidney Foundation

The National Kidney Foundation, a major voluntary nonprofit health organization, is dedicated to preventing kidney and urinary tract diseases, improving the health and well-being of individuals and families affected by kidney disease and increasing the availability of all organs for transplantation.

http://www.kidney.org

Last Updated: 23 Jun 2015

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The Cain Foundation for Branchio-oto-renal Syndrome (BOR)

The CAIN FOUNDATION, a voluntary based Charity. Our mission is to represent the interests of many people affected by Branchio-oto-renal Syndrome and to improve their quality of life by providing support and information related to this Syndrome. We seek to educate both Medical Practitioners and the public by promoting Branchio-oto-renal (BOR) Syndrome awareness. Vision to Educate. Mission to Care.

http://www.thecainfoundation.com

Last Updated: 12 Oct 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic kidney disease" returned 3201 free, full-text research articles on human participants. First 3 results:

Nutritional Risk Screening in patients with chronic kidney disease.
 

Author(s): Rongshao Tan, Jianting Long, Shi Fang, Haiyan Mai, Wei Lu, Yan Liu, Jianrui Wei, Feng Yan

Journal: Asia Pac J Clin Nutr. 2016 ;25(2):249-56.

 

Knowledge concerning nutritional status of patients with chronic kidney disease (CKD) is limited. Nutritional Risk Screening-2002 (NRS-2002) has been used to evaluate the nutritional aspects of patients according to the recommendation of European Society for Clinical Nutrition and ...

Last Updated: 25 May 2016

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Remarks about the study on evaluation of thyroid hormone levels in chronic kidney disease patients.
 

Author(s): Mahmood Dhahir Al-Mendalawi

Journal: Saudi J Kidney Dis Transpl. 2016 May;27(3):617-8.

 

Last Updated: 24 May 2016

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Multinational observational study on clinical practices and therapeutic management of mineral and bone disorders in patients with chronic kidney disease stages 4, 5, and 5D: The OCEANOS study.
 

Author(s): Faissal A M Shaheen, Ramprasad Kurpad, Abdulla A Al-Sayyari, Muhammad Ziad Souqiyyeh, Harith Aljubori, Tarek El Baz, Waqaruddin Kashif, Saltanat Tuganbekova, Kairat Kabulbayev, Faical Jarraya, Mohsen Nafar

Journal: Saudi J Kidney Dis Transpl. 2016 Mar;27(2):290-304.

 

Our aim is to assess the current clinical practices in monitoring and treatment patterns of chronic kidney disease (CKD)-mineral bone disorder and the degree to which these practices met the kidney disease improving global outcome (KDIGO) guidelines. This was an international, multi-center, ...

Last Updated: 21 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic kidney disease" returned 753 free, full-text review articles on human participants. First 3 results:

Management of diabetes mellitus in individuals with chronic kidney disease: therapeutic perspectives and glycemic control.
 

Author(s): Carolina C R Betônico, Silvia M O Titan, Maria Lúcia C Correa-Giannella, Márcia Nery, Márcia Queiroz

Journal: Clinics (Sao Paulo). 2016 Jan;71(1):47-53.

 

The purpose of this study was to evaluate the therapeutic options for diabetes treatment and their potential side effects, in addition to analyzing the risks and benefits of tight glycemic control in patients with diabetic kidney disease. For this review, a search was performed using ...

Last Updated: 13 Feb 2016

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Multiple myeloma: Diagnosis and management issues in patients with pre-existing chronic kidney disease.
 

Author(s): Srilatha Vadlamudi, Siva Nagendra Reddy Annapareddy

Journal: Saudi J Kidney Dis Transpl. 2016 Jan;27(1):9-14.

 

Multiple myeloma is one of the most common malignancies encountered in clinical practice. Renal involvement in myeloma is a well-recognized entity. Although rare, another special situation that a nephrologist can encounter is myeloma occurring in a patient with preexisting chronic ...

Last Updated: 20 Jan 2016

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Strategies for Controlling Blood Pressure and Reducing Cardiovascular Disease Risk in Patients with Chronic Kidney Disease.
 

Author(s): Keith C Norris, Susanne B Nicholas

Journal:

 

Patients with chronic kidney disease (CKD) suffer from an increased prevalence of cardiovascular disease (CVD) risk factors, and a high rate of premature CV morbidity and mortality. The confluence of CV risk factors, in the context of cardio-metabolic perturbations that vary as renal ...

Last Updated: 17 Dec 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Improving Evidence-Based Primary Care for Chronic Kidney Disease
 

Status: Recruiting

Condition Summary: Chronic Kidney Disease; Chronic Kidney Insufficiency; Chronic Renal Diseases; Chronic Renal Insufficiency; Kidney Insufficiency, Chronic

 

Last Updated: 13 Feb 2014

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Primary Cardiovascular Risk Prevention With Aspirin in Chronic Kidney Disease Patients
 

Status: Recruiting

Condition Summary: Chronic Kidney Disease Stage 4; Chronic Kidney Disease Stage 3

 

Last Updated: 17 Oct 2012

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Small-fiber Neuropathy in Chronic Kidney Disease
 

Status: Recruiting

Condition Summary: Small-Fiber Neuropathy; Chronic Kidney Disease

 

Last Updated: 1 Mar 2010

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