Kernicterus

Common Name(s)

Kernicterus

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Kernicterus" for support, advocacy or research.

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CNS Foundation

CNS Foundation's Mission is Three-fold: - Expedite scientific research to find treatments and cures for the more than 14 million children living with some form of neurological disorder - Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology - Educate the public, and public officials, on the critical importance of funding pediatric neurological disorder research

Last Updated: 12 Oct 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Kernicterus" for support, advocacy or research.

Logo
CNS Foundation

CNS Foundation's Mission is Three-fold: - Expedite scientific research to find treatments and cures for the more than 14 million children living with some form of neurological disorder - Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology - Educate the public, and public officials, on the critical importance of funding pediatric neurological disorder research

http://www.cnsfoundation.org

Last Updated: 12 Oct 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Kernicterus" returned 20 free, full-text research articles on human participants. First 3 results:

Neonatal death suspected to be from sepsis was found to be kernicterus with G6PD deficiency.
 

Author(s): Robert D Christensen, Hassan M Yaish, Susan E Wiedmeier, N Scott Reading, Theodore J Pysher, Cheryl Ann Palmer, Josef T Prchal

Journal: Pediatrics. 2013 Dec;132(6):e1694-8.

 

We cared for a term male infant born to Burmese immigrants. At about 24 hours a total serum bilirubin (TSB) was 9.3 mg/dL, and phototherapy was begun. It was stopped 48 hours later, with a TSB of 10.9 mg/dL, and he was discharged from the hospital with an appointment for a repeat ...

Last Updated: 3 Dec 2013

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Acute kernicterus in a neonate with O/B blood group incompatibility and a mutation in SLC4A1.
 

Author(s): Robert D Christensen, Hassan M Yaish, Roberto H Nussenzveig, N Scott Reading, Archana M Agarwal, Larry D Eggert, Josef T Prchal

Journal: Pediatrics. 2013 Aug;132(2):e531-4.

 

We cared for a term female newborn, who at 108 hours of age, with a total serum bilirubin of 15.4 mg/dL, was discharged from the hospital on home phototherapy. At a return appointment 44 hours later, her total serum bilirubin was 41.7 mg/dL and signs of acute kernicterus were present. ...

Last Updated: 2 Aug 2013

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Evidence suggests there was not a "resurgence" of kernicterus in the 1990s.
 

Author(s): Jordan C Brooks, Susan A Fisher-Owens, Yvonne W Wu, David J Strauss, Thomas B Newman

Journal: Pediatrics. 2011 Apr;127(4):672-9.

 

Although some have suggested that kernicterus disappeared in the United States in the 1970s to 1980s and dramatically reappeared in the 1990s, population-based data to support such a resurgence are lacking.

Last Updated: 4 Apr 2011

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Kernicterus" returned 8 free, full-text review articles on human participants. First 3 results:

Cotrimoxazole and neonatal kernicterus: a review.
 

Author(s): Baskaran Thyagarajan, Sharad S Deshpande

Journal: Drug Chem Toxicol. 2014 Apr;37(2):121-9.

 

Sulfamethoxazole (SMX) and trimethoprim (TMP) individually and a combination known as cotrimoxazole (SMX-TMP) are widely used for the treatment of protozoan and bacterial infections. SMX-TMP is also one of the widely used antibiotics administered orally in neonates, along with gentamicin ...

Last Updated: 24 Feb 2014

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Prevention of kernicterus: new guidelines and the critical role of family physicians.
 

Author(s): Elizabeth Shaw, Danielle Grenier

Journal: Can Fam Physician. 2008 Apr;54(4):575-6.

 

Last Updated: 15 Apr 2008

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Genetic factors in neonatal hyperbilirubinemia and kernicterus.
 

Author(s): S Umit Sarici, Mehmet Saldir

Journal: Turk. J. Pediatr.. ;49(3):245-9.

 

Although the relationship between hyperbilirubinemia and genetic factors has long been questioned, the role of genetic factors in the development of severe hyperbilirubinemia and kernicterus has been investigated in detail in the last decade with the rapid progression in molecular ...

Last Updated: 9 Nov 2007

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Determining Prevalence of Acute Bilirubin Encephalopathy in Developing Countries
 

Status: Recruiting

Condition Summary: Demonstrate BIND II Score of >=5, is Valid for Detecting Moderate to Severe ABE in Neonates <14 Days Old.; Demonstrate Community-BIND Instrument, a Modified BIND II, is a Valid and Reliable Tool for Detecting ABE.; Demonstrate That Community-BIND Can be Used for Acquiring Population-based Prevalence of ABE in the Community.

 

Last Updated: 3 Dec 2014

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