Keratoconus

Common Name(s)

Keratoconus

Keratoconus is the degeneration of the structure of the cornea, which is the clear tissue covering the front of the eye. In this condition, the shape of the cornea slowly changes from the normal round shape to a cone shape. Most people who develop keratoconus start out nearsighted, which tends to become worse over time. The cause is unknown, but the tendency to develop keratoconus is probably present from birth. Keratoconus is thought to involve a defect in collagen, the tissue that makes up most of the cornea. Some researchers believe that allergy and eye rubbing may play a role.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Keratoconus" for support, advocacy or research.

National Keratoconus Foundation

The National Keratoconus Foundation (NKCF) is an outreach program of the Discovery Eye Foundation. The NKCF dedicated to the dissemination of information about keratoconus to patients, their families, and eye care professionals.

Last Updated: 15 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Keratoconus" for support, advocacy or research.

National Keratoconus Foundation

The National Keratoconus Foundation (NKCF) is an outreach program of the Discovery Eye Foundation. The NKCF dedicated to the dissemination of information about keratoconus to patients, their families, and eye care professionals.

http://www.nkcf.org/

Last Updated: 15 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

General Resources

KC-Link and NKCF Forum

Email and Web based Support groups

Updated 15 Feb 2013

Go To URL
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Keratoconus" returned 236 free, full-text research articles on human participants. First 3 results:

Comparison of visual, refractive and topographic keratometry outcomes of Intacs and Intacs SK in mild to moderate keratoconus eyes.
 

Author(s): Abdulrahman Al Muammar

Journal: Middle East Afr J Ophthalmol. ;22(1):74-9.

 

The purpose was to evaluate and compare the visual and refractive outcomes, topographic keratometry (K) and complications of Intacs and Intacs SK for mild to moderate keratoconus.

Last Updated: 27 Jan 2015

Go To URL
Changes in corneal sensitivity following cross-linking for progressive early-stage keratoconus.
 

Author(s): Anelise de Medeiros Lago, Belquiz R do Amaral Nassaralla, Larissa Rossana Souza Stival, João Jorge Nassaralla Junior

Journal: Arq Bras Oftalmol. 2014 Apr;77(2):84-7.

 

To evaluate changes in corneal sensitivity following corneal cross-linking (CXL) in patients with progressive earlier stage keratoconus.

Last Updated: 31 Jul 2014

Go To URL
Outcome of corneal collagen crosslinking for progressive keratoconus in paediatric patients.
 

Author(s): Deepa Viswanathan, Nikhil L Kumar, John J Males

Journal: Biomed Res Int. 2014 ;2014():140461.

 

To evaluate the efficacy of corneal collagen crosslinking for progressive keratoconus in paediatric patients.

Last Updated: 11 Jul 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Keratoconus" returned 22 free, full-text review articles on human participants. First 3 results:

Intrastromal corneal ring segments: how successful is the surgical treatment of keratoconus?
 

Author(s): Jorge L Alio, Alfredo Vega-Estrada, Santiago Esperanza, Rafael I Barraquer, Miguel A Teus, Joaquim Murta

Journal: Middle East Afr J Ophthalmol. ;21(1):3-9.

 

This review evaluates the outcomes of intrastromal corneal ring segment (ICRS) implantation for the treatment of keratoconus considering a new grading system based on the preoperative visual impairment of the patient. Additionally, a five-year follow-up analysis of patients with stable ...

Last Updated: 26 Mar 2014

Go To URL
The pathogenesis of keratoconus.
 

Author(s): A E Davidson, S Hayes, A J Hardcastle, S J Tuft

Journal: Eye (Lond). 2014 Feb;28(2):189-95.

 

Keratoconus (KC) is a common degenerative condition that frequently results in visual loss with an onset typically in early adulthood. It is the single most common reason for keratoplasty in the developed world. The cause and underlying pathological mechanism are unknown, but both ...

Last Updated: 13 Feb 2014

Go To URL
Corneal sensitivity in keratoconus: a review of the literature.
 

Author(s): Leopoldo Spadea, Serena Salvatore, Enzo Maria Vingolo

Journal:

 

Corneal sensitivity has recently received much attention given the crucial role the corneal nerves play in maintaining normal corneal structure and function. An increased understanding of the corneal sensitivity and dry eye disease in keratoconus, including alterations of the conjunctival ...

Last Updated: 3 Dec 2013

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Intacs for Keratoconus
 

Status: Recruiting

Condition Summary: Keratoconus

 

Last Updated: 3 Jul 2006

Go to URL
Orthokeratology for Keratoconus
 

Status: Not yet recruiting

Condition Summary: Orthokeratology; Keratoconus

 

Last Updated: 31 Dec 2008

Go to URL
Keratoconus and Ectasia Treatment Plan
 

Status: Available

Condition Summary: Keratoconus; Ectasia

 

Last Updated: 19 Feb 2014

Go to URL