Kawasaki Disease

Common Name(s)

Kawasaki Disease, Acute febrile mucocutaneous lymph node syndrome, Kawasaki syndrome

Kawasaki syndrome is a condition that involves inflammation of the blood vessels.  It is typically diagnosed in young children, but older children and adults can also develop this condition.   Kawasaki syndrome is usually accompanied by a fever that lasts at least 5 days. Other classic symptoms may include red eyes, lips, and mouth; rash; swollen and red hands and feet; and swollen lymph nodes. Kawasaki syndrome occurs most often in people of Asian and Pacific Island descent.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Kawasaki Disease" for support, advocacy or research.

Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

Last Updated: 30 Oct 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Kawasaki Disease" for support, advocacy or research.

Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

http://www.kidswithheart.org

Last Updated: 30 Oct 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Kawasaki Disease" returned 604 free, full-text research articles on human participants. First 3 results:

[Clinical significance of anti-neutrophil cytoplasmic antibodies and anti-endothelial cell antibodies in children with Kawasaki disease].
 

Author(s): Jian-Mei Zhao, Xiao-Hua Wang

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2014 Jul;16(7):740-4.

 

To study the clinical significance of anti-endothelial cell antibodies (AECA) and anti-neutrophil cytoplasmic antibodies (ANCA) in Kawasaki disease (KD) and its complication of coronary arterial lesions (CAL).

Last Updated: 10 Jul 2014

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Epidemiologic features and prognostic factors of coronary artery lesions associated with Kawasaki disease based on a 13-year cohort of consecutive cases identified by complete enumeration surveys in Wakayama, Japan.
 

Author(s): Naomi Kitano, Hiroyuki Suzuki, Takashi Takeuchi, Tomohiro Suenaga, Nobuyuki Kakimoto, Shoichi Shibuta, Norishige Yoshikawa, Tatsuya Takeshita,

Journal: J Epidemiol. 2014 ;24(5):427-34.

 

To clarify the contribution of patient age to the development of coronary artery lesions (CALs) associated with Kawasaki disease (KD), epidemiologic features and prognostic factors were investigated using hospital-based complete enumeration surveys in a specific area.

Last Updated: 8 Sep 2014

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Tropospheric winds from northeastern China carry the etiologic agent of Kawasaki disease from its source to Japan.
 

Author(s): Xavier Rodó, Roger Curcoll, Marguerite Robinson, Joan Ballester, Jane C Burns, Daniel R Cayan, W Ian Lipkin, Brent L Williams, Mara Couto-Rodriguez, Yosikazu Nakamura, Ritei Uehara, Hiroshi Tanimoto, Josep-Anton Morguí

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2014 Jun;111(22):7952-7.

 

Evidence indicates that the densely cultivated region of northeastern China acts as a source for the wind-borne agent of Kawasaki disease (KD). KD is an acute, coronary artery vasculitis of young children, and still a medical mystery after more than 40 y. We used residence times from ...

Last Updated: 14 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Kawasaki Disease" returned 42 free, full-text review articles on human participants. First 3 results:

Management of Kawasaki disease.
 

Author(s): D Eleftheriou, M Levin, D Shingadia, R Tulloh, N J Klein, P A Brogan

Journal: Arch. Dis. Child.. 2014 Jan;99(1):74-83.

 

Kawasaki disease (KD) is an acute self-limiting inflammatory disorder, associated with vasculitis, affecting predominantly medium-sized arteries, particularly the coronary arteries. In developed countries KD is the commonest cause of acquired heart disease in childhood. The aetiology ...

Last Updated: 16 Dec 2013

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Kawasaki disease--the importance of prompt recognition and early referral.
 

Author(s): Daniel Golshevsky, Michael Cheung, David Burgner

Journal: Aust Fam Physician. 2013 Jul;42(7):473-6.

 

Kawasaki disease is an acute, febrile vasculitis of childhood that affects medium sized arteries, particularly the coronary arteries. Consequently, it is the leading cause of paediatric-acquired heart disease in developed countries. It is important to have a high index of suspicion ...

Last Updated: 4 Jul 2013

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Coronary artery sequel of Kawasaki disease in adulthood, a concern for internists and cardiologists.
 

Author(s): Anggoro B Hartopo, Budi Y Setianto

Journal: Acta Med Indones. 2013 Jan;45(1):69-75.

 

Young adults suffered from acute cardiac event, such as acute coronary syndrome, ischemic-associated arrhythmia and sudden death, are frequently encountered without known etiology and significant risk factors. Coronary vasculitis due to Kawasaki disease contributes to be a risk factor ...

Last Updated: 15 Apr 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Etanercept in Kawasaki Disease
 

Status: Recruiting

Condition Summary: Mucocutaneous Lymph Node Syndrome; Kawasaki Disease

 

Last Updated: 15 Sep 2014

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Epidemiologic Features of Kawasaki Disease in Shanghai From 2008 Through 2012
 

Status: Recruiting

Condition Summary: Kawasaki Disease

 

Last Updated: 16 Dec 2014

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Last Updated: 19 Nov 2014

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