Juvenile myoclonic epilepsy

Common Name(s)

Juvenile myoclonic epilepsy

Juvenile myoclonic epilepsy is an epilepsy syndrome characterized by myoclonic jerks (quick jerks of the arms or legs), generalized tonic-clonic seizures (GTCSs), and sometimes, absence seizures.  The seizures of juvenile myoclonic epilepsy often occur when people first awaken in the morning, especially if they are sleep-deprived. Drinking alcohol and psychological stress may also make these seizures more likely.  Onset typically occurs around adolesence in otherwise healthy children.  The exact cause of juvenile myoclonic epilepsy remains unknown.  Although patients usually require lifelong treatment with anticonvulsants, their overall prognosis is generally good.


 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Juvenile myoclonic epilepsy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Juvenile myoclonic epilepsy" returned 157 free, full-text research articles on human participants. First 3 results:

Late-onset Juvenile Myoclonic Epilepsy or Frontal Lobe Epilepsy with Myoclonus.
 

Author(s): Xin-Yue Zhang, Jin-Bei Yu, Dan Yang, Chun-Tao Han, Wei-Hong Lin

Journal: Chin. Med. J.. 2016 10;129(20):2508-2509.

 

Last Updated: 17 Oct 2016

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Cognitive performance in juvenile myoclonic epilepsy patients with specific endophenotypes.
 

Author(s): Kelly Cristina de Carvalho, Carina Gonçalves Pedroso Uchida, Mirian Salvadori Bittar Guaranha, Laura Maria F F Guilhoto, Peter Wolf, Elza Márcia Targas Yacubian

Journal: Seizure. 2016 Aug;40():33-41.

 

Juvenile myoclonic epilepsy (JME) is a heterogeneous syndrome in which seizures can be precipitated not only by non-specific factors, such as sleep deprivation and stress, but also by specific stimuli, such as photic stimuli, eye-closure, praxis, and language. The presence of these ...

Last Updated: 29 Jul 2016

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High-dose versus low-dose valproate for the treatment of juvenile myoclonic epilepsy: Going from low to high.
 

Author(s): Laura E Hernández-Vanegas, Aurelio Jara-Prado, Adriana Ochoa, Nayelli Rodríguez Y Rodríguez, Reyna M Durón, Daniel Crail-Meléndez, Ma Elisa Alonso, Antonio V Delgado-Escueta, Iris E Martínez-Juárez

Journal: Epilepsy Behav. 2016 Aug;61():34-40.

 

Juvenile myoclonic epilepsy (JME) is a genetic generalized epilepsy accounting for 3-12% of adult cases of epilepsy. Valproate has proven to be the first-choice drug in JME for controlling the most common seizure types: myoclonic, absence, and generalized tonic-clonic (GTC). In this ...

Last Updated: 1 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Juvenile myoclonic epilepsy" returned 10 free, full-text review articles on human participants. First 3 results:

Genetic susceptibility in Juvenile Myoclonic Epilepsy: Systematic review of genetic association studies.
 

Author(s): Bruna Priscila Dos Santos, Chiara Rachel Maciel Marinho, Thalita Ewellyn Batista Sales Marques, Layanne Kelly Gomes Angelo, Maísa Vieira da Silva Malta, Marcelo Duzzioni, Olagide Wagner de Castro, João Pereira Leite, Fabiano Timbó Barbosa, Daniel Leite Góes Gitaí

Journal:

 

Several genetic association investigations have been performed over the last three decades to identify variants underlying Juvenile Myoclonic Epilepsy (JME). Here, we evaluate the accumulating findings and provide an updated perspective of these studies.

Last Updated: 21 Jun 2017

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Transition issues for benign epilepsy with centrotemporal spikes, nonlesional focal epilepsy in otherwise normal children, childhood absence epilepsy, and juvenile myoclonic epilepsy.
 

Author(s): Carol S Camfield, Anne Berg, Ulrich Stephani, Elaine C Wirrell

Journal: Epilepsia. 2014 Aug;55 Suppl 3():16-20.

 

This chapter covers the syndromes of benign epilepsy with centrotemporal spikes (BECTS), nonlesional focal epilepsy in otherwise normal children (NLFN), and the genetic generalized epilepsies. BECTS is an epilepsy syndrome that always enters terminal remission before the general age ...

Last Updated: 11 Sep 2014

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Oxcarbazepine-induced myoclonic status epilepticus in juvenile myoclonic epilepsy.
 

Author(s): Martina Fanella, Gabriella Egeo, Jinane Fattouch, Sara Casciato, Leonardo Lapenta, Alessandra Morano, Anna Teresa Giallonardo, Carlo Di Bonaventura

Journal: Epileptic Disord. 2013 Jun;15(2):181-7.

 

Juvenile myoclonic epilepsy (JME) is a frequent idiopathic generalised epilepsy syndrome with typical clinical and EEG features that can usually be controlled by valproate monotherapy. JME may be underdiagnosed or misdiagnosed; in the latter case, it may be mistaken for partial epilepsy. ...

Last Updated: 3 Jul 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

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