Juvenile myoclonic epilepsy

Common Name(s)

Juvenile myoclonic epilepsy

Juvenile myoclonic epilepsy is an epilepsy syndrome characterized by myoclonic jerks (quick jerks of the arms or legs), generalized tonic-clonic seizures (GTCSs), and sometimes, absence seizures.  The seizures of juvenile myoclonic epilepsy often occur when people first awaken in the morning, especially if they are sleep-deprived. Drinking alcohol and psychological stress may also make these seizures more likely.  Onset typically occurs around adolesence in otherwise healthy children.  The exact cause of juvenile myoclonic epilepsy remains unknown.  Although patients usually require lifelong treatment with anticonvulsants, their overall prognosis is generally good.


 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Juvenile myoclonic epilepsy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Juvenile myoclonic epilepsy" returned 83 free, full-text research articles on human participants. First 3 results:

Circadian rhythm and profile in patients with juvenile myoclonic epilepsy and temporal lobe epilepsy.
 

Author(s): Aya Fukuda, Mateus P Funari, Paula T Fernandes, Carlos Mantovani Guerreiro, Li Min Li

Journal: Arq Neuropsiquiatr. 2015 Jan;73(1):3-6.

 

This study intended to compare the circadian rhythm and circadian profile between patients with juvenile myoclonic epilepsy (JME) and patients with temporal lobe epilepsy (TLE).

Last Updated: 22 Jan 2015

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Motor co-activation in siblings of patients with juvenile myoclonic epilepsy: an imaging endophenotype?
 

Author(s): Britta Wandschneider, Maria Centeno, Christian Vollmar, Mark Symms, Pamela J Thompson, John S Duncan, Matthias J Koepp

Journal: Brain. 2014 Sep;137(Pt 9):2469-79.

 

Juvenile myoclonic epilepsy is a heritable idiopathic generalized epilepsy syndrome, characterized by myoclonic jerks and frequently triggered by cognitive effort. Impairment of frontal lobe cognitive functions has been reported in patients with juvenile myoclonic epilepsy and their ...

Last Updated: 15 Aug 2014

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PER2 rs2304672, CLOCK rs1801260, and PER3 rs57875989 polymorphisms are not associated with juvenile myoclonic epilepsy.
 

Author(s): Bruna Santos, Thalita Marques, Maísa Malta, Fernando Gameleira, Rodrigo Secolin, Tiago Andrade, Lívia Gitaí, Daniel Gitaí

Journal: Epilepsy Behav. 2014 Jul;36():82-5.

 

Sleep disturbance is common in several epilepsy types, such as juvenile myoclonic epilepsy (JME). Genetic background could increase susceptibility to seizure and sleep abnormalities. From this perspective, a susceptibility gene for sleep disturbance or chronotype could contribute ...

Last Updated: 14 Jul 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Juvenile myoclonic epilepsy" returned 4 free, full-text review articles on human participants. First 3 results:

[Juvenile myoclonic epilepsy].
 

Author(s): Marte Roa Syvertsen, Rune Markhus, Kaja Kristine Selmer, Karl O Nakken

Journal: Tidsskr. Nor. Laegeforen.. 2012 Aug;132(14):1610-3.

 

Juvenile myoclonic epilepsy (JME) is a generalised epilepsy with seizure onset in youth. The aim of this review is to present updated knowledge about the etiology, diagnosis and treatment of JME.

Last Updated: 9 Aug 2012

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Juvenile myoclonic epilepsy.
 

Author(s): Isabel Alfradique, Marcio Moacyr Vasconcelos

Journal: Arq Neuropsiquiatr. 2007 Dec;65(4B):1266-71.

 

Juvenile myoclonus epilepsy (JME) is a common epileptic syndrome, the etiology of which is genetically determined. Its onset occurs from 6 through 22 years of age, and affected patients present with myoclonic jerks, often associated with generalized tonic-clonic seizures - the most ...

Last Updated: 17 Mar 2008

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Juvenile myoclonic epilepsy: under-appreciated and under-diagnosed.
 

Author(s): R Renganathan, N Delanty

Journal: Postgrad Med J. 2003 Feb;79(928):78-80.

 

Juvenile myoclonic epilepsy (JME) is a hereditary, idiopathic, generalised epilepsy and is found in 5%-11% of patients with epilepsy. It is characterised by myoclonic jerks, occasional generalised tonic-clonic seizures, and sometimes absence seizures. JME continues to be under-appreciated ...

Last Updated: 3 Mar 2003

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Physical Exercise in Subjects With Juvenile Myoclonic Epilepsy
 

Status: Recruiting

Condition Summary: Epilepsy; Epilepsia; Epileptic Seizures; Seizure Disorder

 

Last Updated: 9 Oct 2011

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