Juvenile myoclonic epilepsy

Common Name(s)

Juvenile myoclonic epilepsy

Juvenile myoclonic epilepsy is an epilepsy syndrome characterized by myoclonic jerks (quick jerks of the arms or legs), generalized tonic-clonic seizures (GTCSs), and sometimes, absence seizures.  The seizures of juvenile myoclonic epilepsy often occur when people first awaken in the morning, especially if they are sleep-deprived. Drinking alcohol and psychological stress may also make these seizures more likely.  Onset typically occurs around adolesence in otherwise healthy children.  The exact cause of juvenile myoclonic epilepsy remains unknown.  Although patients usually require lifelong treatment with anticonvulsants, their overall prognosis is generally good.


 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Juvenile myoclonic epilepsy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Juvenile myoclonic epilepsy" returned 142 free, full-text research articles on human participants. First 3 results:

Extrafrontal structural changes in juvenile myoclonic epilepsy: a topographic analysis of combined structural and microstructural brain imaging.
 

Author(s): Seong Hoon Kim, Sung-Chul Lim, Woojun Kim, Oh-Hun Kwon, Seun Jeon, Jong-Min Lee, Young-Min Shon

Journal: Seizure. 2015 Aug;30():124-31.

 

An increasing amount of evidence has demonstrated that juvenile myoclonic epilepsy (JME) is associated with structural abnormalities in not only the thalamofrontal system but its adjacent regions such as temporal or parieto-occipital areas. The goal of this study was to systematically ...

Last Updated: 28 Jul 2015

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Abnormal motor cortex plasticity in juvenile myoclonic epilepsy.
 

Author(s): Gionata Strigaro, Lina Falletta, Annalisa Cerino, Chiara Pizzamiglio, Giacomo Tondo, Claudia Varrasi, Roberto Cantello

Journal: Seizure. 2015 Aug;30():101-5.

 

Abnormal cortical plasticity has been hypothesized to play a crucial role in the pathogenesis of juvenile myoclonic epilepsy (JME). To study the motor cortical plasticity we used paired associative stimulation (PAS). When a repetitive electrical stimulus to the median nerve is paired ...

Last Updated: 28 Jul 2015

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Neuropsychological profiles of patients with juvenile myoclonic epilepsy and their siblings: An extended study.
 

Author(s): Nasur Iqbal, Helen Caswell, Robin Muir, Amy Cadden, Stuart Ferguson, Holly Mackenzie, Philip Watson, Susan Duncan

Journal: Epilepsia. 2015 Aug;56(8):1301-8.

 

To examine executive function, intelligence, visuospatial skills, language, memory, attention, reaction time, anxiety, depression, and emotional and behavioral traits most frequently associated with executive dysfunction in patients with juvenile myoclonic epilepsy (JME) compared ...

Last Updated: 3 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Juvenile myoclonic epilepsy" returned 8 free, full-text review articles on human participants. First 3 results:

Transition issues for benign epilepsy with centrotemporal spikes, nonlesional focal epilepsy in otherwise normal children, childhood absence epilepsy, and juvenile myoclonic epilepsy.
 

Author(s): Carol S Camfield, Anne Berg, Ulrich Stephani, Elaine C Wirrell

Journal: Epilepsia. 2014 Aug;55 Suppl 3():16-20.

 

This chapter covers the syndromes of benign epilepsy with centrotemporal spikes (BECTS), nonlesional focal epilepsy in otherwise normal children (NLFN), and the genetic generalized epilepsies. BECTS is an epilepsy syndrome that always enters terminal remission before the general age ...

Last Updated: 11 Sep 2014

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Frontal lobe function and structure in juvenile myoclonic epilepsy: a comprehensive review of neuropsychological and imaging data.
 

Author(s): Britta Wandschneider, Pamela J Thompson, Christian Vollmar, Matthias J Koepp

Journal: Epilepsia. 2012 Dec;53(12):2091-8.

 

Juvenile myoclonic epilepsy is the most common idiopathic epilepsy syndrome and is considered a benign seizure disorder that responds well to antiepileptic drug treatment, in particular sodium valproate. By definition, routine brain imaging shows no abnormalities, but advanced imaging ...

Last Updated: 4 Dec 2012

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[Juvenile myoclonic epilepsy].
 

Author(s): Marte Roa Syvertsen, Rune Markhus, Kaja Kristine Selmer, Karl O Nakken

Journal: Tidsskr. Nor. Laegeforen.. 2012 Aug;132(14):1610-3.

 

Juvenile myoclonic epilepsy (JME) is a generalised epilepsy with seizure onset in youth. The aim of this review is to present updated knowledge about the etiology, diagnosis and treatment of JME.

Last Updated: 9 Aug 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Physical Exercise in Subjects With Juvenile Myoclonic Epilepsy
 

Status: Recruiting

Condition Summary: Epilepsy; Epilepsia; Epileptic Seizures; Seizure Disorder

 

Last Updated: 9 Oct 2011

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