Juvenile dermatomyositis

Common Name(s)

Juvenile dermatomyositis

Juvenile dermatomyositis has some similarities to adult dermatomyositis and polymyositis. It typically affects children ages 2 to 15 years, with symptoms that include weakness of the muscles close to the trunk of the body, inflammation, edema, muscle pain, fatigue, skin rashes, abdominal pain, fever, and contractures. Children with juvenile dermatomyositis may have difficulty swallowing and breathing, and the heart may also be affected.  About 20 to 30 percent of children with juvenile dermatomyositis develop calcium deposits in the soft tissue. Affected children may not show higher than normal levels of the muscle enzyme creatine kinase in their blood but have higher than normal levels of other muscle enzymes.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Juvenile dermatomyositis" for support, advocacy or research.

Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

Last Updated: 2 Aug 2013

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The Myositis Association

The mission of the Myositis Association is to: - Provide support to myositis patients and their families - Provide connections between the Medical Advisory Board and the general medical and patient communities - Increase funding to support myositis research

Last Updated: 14 Jan 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Juvenile dermatomyositis" for support, advocacy or research.

Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

http://www.isabellasaviary.com

Last Updated: 2 Aug 2013

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The Myositis Association

The mission of the Myositis Association is to: - Provide support to myositis patients and their families - Provide connections between the Medical Advisory Board and the general medical and patient communities - Increase funding to support myositis research

http://www.myositis.org

Last Updated: 14 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Juvenile dermatomyositis" returned 145 free, full-text research articles on human participants. First 3 results:

Clinical characteristics of children with juvenile dermatomyositis: the Childhood Arthritis and Rheumatology Research Alliance Registry.
 

Author(s): Angela Byun Robinson, Mark F Hoeltzel, Dawn M Wahezi, Mara L Becker, Elizabeth A Kessler, Heinrike Schmeling, Ruy Carrasco, Adam M Huber, Brian M Feldman, Ann M Reed,

Journal: Arthritis Care Res (Hoboken). 2014 Mar;66(3):404-10.

 

To investigate aspects of juvenile dermatomyositis (DM), including disease characteristics and treatment, through a national multicenter registry.

Last Updated: 4 Mar 2014

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Disease patterns of juvenile dermatomyositis from Western India.
 

Author(s): Pranav R Chickermane, Deepali Mankad, Raju P Khubchandani

Journal: Indian Pediatr. 2013 Oct;50(10):961-3.

 

A retrospective assessment of clinical characteristics, complications/ associations, laboratory investigations, treatment modalities and outcome in an inceptional cohort of 22 (male-13) children with juvenile dermatomyositis (JDM) receiving treatment at Jaslok Hospital, Mumbai during ...

Last Updated: 13 Nov 2013

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Chronic nonbacterial osteomyelitis in a child with previous juvenile dermatomyositis.
 

Author(s): Daniela S Ardelean, Peter B Dent, Polly J Ferguson, Ronald M Laxer

Journal: J. Rheumatol.. 2013 Mar;40(3):339-40.

 

Last Updated: 4 Mar 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Juvenile dermatomyositis" returned 10 free, full-text review articles on human participants. First 3 results:

Type I interferon pathway in adult and juvenile dermatomyositis.
 

Author(s): Emily C Baechler, Hatice Bilgic, Ann M Reed

Journal: Arthritis Res. Ther.. 2011 ;13(6):249.

 

Gene expression profiling and protein studies of the type I interferon pathway have revealed important insights into the disease process in adult and juvenile dermatomyositis. The most prominent and consistent feature has been a characteristic whole blood gene signature indicating ...

Last Updated: 28 Mar 2012

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Consensus treatments for moderate juvenile dermatomyositis: beyond the first two months. Results of the second Childhood Arthritis and Rheumatology Research Alliance consensus conference.
 

Author(s): Adam M Huber, Angela B Robinson, Ann M Reed, Leslie Abramson, Sharon Bout-Tabaku, Ruy Carrasco, Megan Curran, Brian M Feldman, Harry Gewanter, Thomas Griffin, Kathleen Haines, Mark F Hoeltzel, Josephine Isgro, Philip Kahn, Bianca Lang, Patti Lawler, Bracha Shaham, Heinrike Schmeling, Rosie Scuccimarri, Michael Shishov, Elizabeth Stringer, Julie Wohrley, Norman T Ilowite, Carol Wallace,

Journal: Arthritis Care Res (Hoboken). 2012 Apr;64(4):546-53.

 

To use consensus methods and the considerable expertise contained within the Childhood Arthritis and Rheumatology Research Alliance (CARRA) organization to extend the 3 previously developed treatment plans for moderate juvenile dermatomyositis (DM) to span the full course of treatment.

Last Updated: 29 Mar 2012

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Five-year Actively Controlled Clinical Trial in New Onset Juvenile Dermatomyositis
 

Status: Recruiting

Condition Summary: Juvenile Dermatomyositis

 

Last Updated: 16 Feb 2011

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Creatine Supplementation in Pediatric Rheumatology
 

Status: Recruiting

Condition Summary: Juvenile Systemic Lupus Erythematosus; Juvenile Dermatomyositis

 

Last Updated: 12 Jan 2012

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Compassionate Use Protocol for the Treatment of Autoinflammatory Syndromes
 

Status: Available

Condition Summary: Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE); Juvenile Dermatomyositis (JDM)

 

Last Updated: 24 Jan 2014

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