Japanese encephalitis

Common Name(s)

Japanese encephalitis

Japanese Encephalitis (JE) is a viral disease that infects humans and animals. JE causes inflammation of the membranes around the brain. It is transmitted to humans through bites from infected mosquitoes. This disease is mainly in rural and partially urban settings, with transmission often increasing during the rainy seasons, when large epidemics can occur. Signs and symptoms of JE are typically mild and include fever and headache. More severe symptoms of JE include rapid onset of high fever, headache, neck stiffness, disorientation, coma, seizures, spastic paralysis, and death. Those who survive may suffer permanent intellectual, behavioral, or neurological problems, such as paralysis, recurrent seizures, or the inability to speak. There is currently no cure for JE, but safe and effective vaccines are available to prevent JE.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Japanese encephalitis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Japanese encephalitis" returned 346 free, full-text research articles on human participants. First 3 results:

Forecasting Japanese encephalitis incidence from historical morbidity patterns: Statistical analysis with 27 years of observation in Assam, India.
 

Author(s): Bijoy K Handique, Siraj A Khan, J Mahanta, S Sudhakar

Journal: J Vector Borne Dis. 2014 Sep;51(3):172-8.

 

Japanese encephalitis (JE) is one of the dreaded mosquito-borne viral diseases mostly prevalent in south Asian countries including India. Early warning of the disease in terms of disease intensity is crucial for taking adequate and appropriate intervention measures. The present study ...

Last Updated: 25 Sep 2014

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An appraisal of clinicopathological parameters in Japanese encephalitis and changing epidemiological trends in upper Assam, India.
 

Author(s): Saurav Jyoti Patgiri, Achinta K Borthakur, Biswajyoti Borkakoty, Lahari Saikia, Ridip Dutta, Sanjib K Phukan

Journal: Indian J Pathol Microbiol. ;57(3):400-6.

 

Japanese encephalitis (JE), an acute mosquito-borne viral disease, is one of the leading causes of viral encephalitis in the South-East Asian region. JE is endemic in Assam. The morbidity and mortality due to JE is significant with outbreaks every year during the monsoons.

Last Updated: 14 Aug 2014

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A molecularly cloned, live-attenuated japanese encephalitis vaccine SA14-14-2 virus: a conserved single amino acid in the ij Hairpin of the Viral E glycoprotein determines neurovirulence in mice.
 

Author(s): Sang-Im Yun, Byung-Hak Song, Jin-Kyoung Kim, Gil-Nam Yun, Eun-Young Lee, Long Li, Richard J Kuhn, Michael G Rossmann, John D Morrey, Young-Min Lee

Journal:

 

Japanese encephalitis virus (JEV), a mosquito-borne flavivirus that causes fatal neurological disease in humans, is one of the most important emerging pathogens of public health significance. JEV represents the JE serogroup, which also includes West Nile, Murray Valley encephalitis, ...

Last Updated: 1 Aug 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Japanese encephalitis" returned 19 free, full-text review articles on human participants. First 3 results:

Antioxidants: potential antiviral agents for Japanese encephalitis virus infection.
 

Author(s): Yu Zhang, Zehua Wang, Huan Chen, Zongtao Chen, Yanping Tian

Journal: Int. J. Infect. Dis.. 2014 Jul;24():30-6.

 

Japanese encephalitis (JE) is prevalent throughout eastern and southern Asia and the Pacific Rim. It is caused by the JE virus (JEV), which belongs to the family Flaviviridae. Despite the importance of JE, little is known about its pathogenesis. The role of oxidative stress in the ...

Last Updated: 14 Jun 2014

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Estimating the burden of Japanese encephalitis virus and other encephalitides in countries of the mekong region.
 

Author(s): Arnaud Tarantola, Flavie Goutard, Paul Newton, Xavier de Lamballerie, Olivier Lortholary, Julien Cappelle, Philippe Buchy

Journal:

 

Diverse aetiologies of viral and bacterial encephalitis are widely recognized as significant yet neglected public health issues in the Mekong region. A robust analysis of the corresponding health burden is lacking. We retrieved 75 articles on encephalitis in the region published in ...

Last Updated: 5 Feb 2014

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Biomarkers in Japanese encephalitis: a review.
 

Author(s): Ravi Kant Upadhyay

Journal: Biomed Res Int. 2013 ;2013():591290.

 

JE is a flavivirus generated dreadful CNS disease which causes high mortality in various pediatric groups. JE disease is currently diagnosed by measuring the level of viral antigens and virus neutralization IgM antibodies in blood serum and CSF by ELISA. However, it is not possible ...

Last Updated: 23 Jan 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Treatment of Japanese Encephalitis
 

Status: Recruiting

Condition Summary: Japanese Encephalitis

 

Last Updated: 8 Feb 2006

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Antibody Response of a Boosted Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in Children
 

Status: Not yet recruiting

Condition Summary: Japanese Encephalitis

 

Last Updated: 6 Oct 2013

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Post-licensure Safety Study of IMOJEVĀ® in Thailand
 

Status: Recruiting

Condition Summary: Japanese Encephalitis

 

Last Updated: 11 Nov 2014

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