Japanese encephalitis

Common Name(s)

Japanese encephalitis

Japanese Encephalitis (JE) is a viral disease that infects humans and animals. JE causes inflammation of the membranes around the brain. It is transmitted to humans through bites from infected mosquitoes. This disease is mainly in rural and partially urban settings, with transmission often increasing during the rainy seasons, when large epidemics can occur. Signs and symptoms of JE are typically mild and include fever and headache. More severe symptoms of JE include rapid onset of high fever, headache, neck stiffness, disorientation, coma, seizures, spastic paralysis, and death. Those who survive may suffer permanent intellectual, behavioral, or neurological problems, such as paralysis, recurrent seizures, or the inability to speak. There is currently no cure for JE, but safe and effective vaccines are available to prevent JE.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Japanese encephalitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Japanese encephalitis" returned 335 free, full-text research articles on human participants. First 3 results:

Use of Japanese encephalitis vaccine in US travel medicine practices in Global TravEpiNet.
 

Author(s): Bhushan R Deshpande, Sowmya R Rao, Emily S Jentes, Susan L Hills, Marc Fischer, Mark D Gershman, Gary W Brunette, Edward T Ryan, Regina C LaRocque,

Journal: Am. J. Trop. Med. Hyg.. 2014 Oct;91(4):694-8.

 

Few data regarding the use of Japanese encephalitis (JE) vaccine in clinical practice are available. We identified 711 travelers at higher risk and 7,578 travelers at lower risk for JE who were seen at US Global TravEpiNet sites from September of 2009 to August of 2012. Higher-risk ...

Last Updated: 2 Oct 2014

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Finding of B cell epitope within polyprotein of Japanese encephalitis virus: a clue for development of new Japanese encephalitis vaccine.
 

Author(s): Sora Yasri, Viroj Wiwanitkit

Journal: Arq Neuropsiquiatr. 2014 Jun;72(6):478.

 

Last Updated: 26 Jun 2014

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Safety and immunogenicity of live-attenuated Japanese encephalitis SA 14-14-2 vaccine co-administered with measles vaccine in 9-month-old infants in Sri Lanka.
 

Author(s): Pushpa Ranjan Wijesinghe, M R Nihal Abeysinghe, Sutee Yoksan, Yafu Yao, Benli Zhou, Lei Zhang, Mansour Yaich, Kathleen M Neuzil, John C Victor

Journal: Vaccine. 2014 Aug;32(37):4751-7.

 

To facilitate introduction of live attenuated SA 14-14-2 Japanese encephalitis vaccine (LJEV) into the National Immunization Programme of Sri Lanka, we evaluated the safety and immunogenicity of co-administration of LJEV and measles vaccine at 9 months of age. Serum immune responses ...

Last Updated: 4 Aug 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Japanese encephalitis" returned 19 free, full-text review articles on human participants. First 3 results:

Antioxidants: potential antiviral agents for Japanese encephalitis virus infection.
 

Author(s): Yu Zhang, Zehua Wang, Huan Chen, Zongtao Chen, Yanping Tian

Journal: Int. J. Infect. Dis.. 2014 Jul;24():30-6.

 

Japanese encephalitis (JE) is prevalent throughout eastern and southern Asia and the Pacific Rim. It is caused by the JE virus (JEV), which belongs to the family Flaviviridae. Despite the importance of JE, little is known about its pathogenesis. The role of oxidative stress in the ...

Last Updated: 14 Jun 2014

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Estimating the burden of Japanese encephalitis virus and other encephalitides in countries of the mekong region.
 

Author(s): Arnaud Tarantola, Flavie Goutard, Paul Newton, Xavier de Lamballerie, Olivier Lortholary, Julien Cappelle, Philippe Buchy

Journal:

 

Diverse aetiologies of viral and bacterial encephalitis are widely recognized as significant yet neglected public health issues in the Mekong region. A robust analysis of the corresponding health burden is lacking. We retrieved 75 articles on encephalitis in the region published in ...

Last Updated: 5 Feb 2014

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Biomarkers in Japanese encephalitis: a review.
 

Author(s): Ravi Kant Upadhyay

Journal: Biomed Res Int. 2013 ;2013():591290.

 

JE is a flavivirus generated dreadful CNS disease which causes high mortality in various pediatric groups. JE disease is currently diagnosed by measuring the level of viral antigens and virus neutralization IgM antibodies in blood serum and CSF by ELISA. However, it is not possible ...

Last Updated: 23 Jan 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Treatment of Japanese Encephalitis
 

Status: Recruiting

Condition Summary: Japanese Encephalitis

 

Last Updated: 8 Feb 2006

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Antibody Response of a Boosted Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in Children
 

Status: Not yet recruiting

Condition Summary: Japanese Encephalitis

 

Last Updated: 6 Oct 2013

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Post-licensure Safety Study of IMOJEVĀ® in Thailand
 

Status: Recruiting

Condition Summary: Japanese Encephalitis

 

Last Updated: 11 Nov 2014

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