Japanese encephalitis

Common Name(s)

Japanese encephalitis

Japanese Encephalitis (JE) is a viral disease that infects humans and animals. JE causes inflammation of the membranes around the brain. It is transmitted to humans through bites from infected mosquitoes. This disease is mainly in rural and partially urban settings, with transmission often increasing during the rainy seasons, when large epidemics can occur. Signs and symptoms of JE are typically mild and include fever and headache. More severe symptoms of JE include rapid onset of high fever, headache, neck stiffness, disorientation, coma, seizures, spastic paralysis, and death. Those who survive may suffer permanent intellectual, behavioral, or neurological problems, such as paralysis, recurrent seizures, or the inability to speak. There is currently no cure for JE, but safe and effective vaccines are available to prevent JE.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Japanese encephalitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Japanese encephalitis" returned 320 free, full-text research articles on human participants. First 3 results:

Molecular characterization of full-length genome of Japanese encephalitis virus genotype V isolated from Tibet, China.
 

Author(s): Ming Hua Li, Shi Hong Fu, Wei Xin Chen, Huan Yu Wang, Yu Xi Cao, Guo Dong Liang

Journal: Biomed. Environ. Sci.. 2014 Apr;27(4):231-9.

 

To determine the molecular characterization of full-length genome of Japanese encephalitis virus (JEV) genotype V.

Last Updated: 24 Apr 2014

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Investigation of dengue and Japanese encephalitis virus transmission in Hanam, Viet Nam.
 

Author(s): Annette Fox, Stephen Whitehead, Katherine L Anders, Le Nguyen Minh Hoa, Le Quynh Mai, Pham Quang Thai, Nguyen Thu Yen, Tran Nhu Duong, Dang Dinh Thoang, Jeremy Farrar, Heiman Wertheim, Cameron Simmons, Nguyen Tran Hien, Peter Horby

Journal: Am. J. Trop. Med. Hyg.. 2014 May;90(5):892-6.

 

This study investigated whether a large dengue epidemic that struck Hanoi in 2009 also affected a nearby semirural area. Seroconversion (dengue virus-reactive immunoglobulin G enzyme-linked immunosorbent assay) was high during 2009 compared with 2008, but neutralization assays showed ...

Last Updated: 8 May 2014

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Clinical profile and outcome of Japanese encephalitis in children admitted with acute encephalitis syndrome.
 

Author(s): Gitali Kakoti, Prafulla Dutta, Bishnu Ram Das, Jani Borah, Jagadish Mahanta

Journal: Biomed Res Int. 2013 ;2013():152656.

 

Japanese encephalitis (JE) is an arthropod borne viral disease. Children are most commonly affected in Southeast Asian region showing symptoms of central nervous system with several complications and death. The clinical characteristics and outcomes in pediatric JE patients hospitalized ...

Last Updated: 3 Feb 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Japanese encephalitis" returned 17 free, full-text review articles on human participants. First 3 results:

Estimating the burden of Japanese encephalitis virus and other encephalitides in countries of the mekong region.
 

Author(s): Arnaud Tarantola, Flavie Goutard, Paul Newton, Xavier de Lamballerie, Olivier Lortholary, Julien Cappelle, Philippe Buchy

Journal:

 

Diverse aetiologies of viral and bacterial encephalitis are widely recognized as significant yet neglected public health issues in the Mekong region. A robust analysis of the corresponding health burden is lacking. We retrieved 75 articles on encephalitis in the region published in ...

Last Updated: 5 Feb 2014

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Biomarkers in Japanese encephalitis: a review.
 

Author(s): Ravi Kant Upadhyay

Journal: Biomed Res Int. 2013 ;2013():591290.

 

JE is a flavivirus generated dreadful CNS disease which causes high mortality in various pediatric groups. JE disease is currently diagnosed by measuring the level of viral antigens and virus neutralization IgM antibodies in blood serum and CSF by ELISA. However, it is not possible ...

Last Updated: 23 Jan 2014

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Review of climate, landscape, and viral genetics as drivers of the Japanese encephalitis virus ecology.
 

Author(s): Guillaume Le Flohic, Vincent Porphyre, Philippe Barbazan, Jean-Paul Gonzalez

Journal:

 

The Japanese encephalitis virus (JEV), an arthropod-born Flavivirus, is the major cause of viral encephalitis, responsible for 10,000-15,000 deaths each year, yet is a neglected tropical disease. Since the JEV distribution area has been large and continuously extending toward new ...

Last Updated: 26 Sep 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Treatment of Japanese Encephalitis
 

Status: Recruiting

Condition Summary: Japanese Encephalitis

 

Last Updated: 8 Feb 2006

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Antibody Response of a Boosted Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in Children
 

Status: Not yet recruiting

Condition Summary: Japanese Encephalitis

 

Last Updated: 6 Oct 2013

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Post-licensure Safety Study of IMOJEVĀ® in Thailand
 

Status: Recruiting

Condition Summary: Japanese Encephalitis

 

Last Updated: 6 May 2014

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