Japanese encephalitis

Common Name(s)

Japanese encephalitis

Japanese Encephalitis (JE) is a viral disease that infects humans and animals. JE causes inflammation of the membranes around the brain. It is transmitted to humans through bites from infected mosquitoes. This disease is mainly in rural and partially urban settings, with transmission often increasing during the rainy seasons, when large epidemics can occur. Signs and symptoms of JE are typically mild and include fever and headache. More severe symptoms of JE include rapid onset of high fever, headache, neck stiffness, disorientation, coma, seizures, spastic paralysis, and death. Those who survive may suffer permanent intellectual, behavioral, or neurological problems, such as paralysis, recurrent seizures, or the inability to speak. There is currently no cure for JE, but safe and effective vaccines are available to prevent JE.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Japanese encephalitis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Japanese encephalitis" returned 378 free, full-text research articles on human participants. First 3 results:

A model immunization programme to control Japanese encephalitis in Viet Nam.
 

Author(s): Nguyen Thu Yen, Wei Liu, Hoang Duc Hanh, Na Yoon Chang, Tran Nhu Duong, Robert V Gibbons, Florian Marks, Nghiem Anh Thu, Nguyen Minh Hong, Jin Kyung Park, Pham Anh Tuan, Ananda Nisalak, John D Clemens, Zhi-Yi Xu

Journal: J Health Popul Nutr. 2015 Mar;33(1):207-13.

 

In Viet Nam, an inactivated, mouse brain-derived vaccine for Japanese encephalitis (JE) has been given exclusively to ≤ 5 years old children in 3 paediatric doses since 1997. However, JE incidence remained high, especially among children aged 5-9 years. We conducted a model JE immunization ...

Last Updated: 21 May 2015

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The Immunogenicity and Safety of the Live-attenuated SA 14-14-2 Japanese Encephalitis Vaccine Given with a Two-dose Primary Schedule in Children.
 

Author(s): Hyo Jin Kwon, Soo Young Lee, Ki Hwan Kim, Dong Soo Kim, Sung Ho Cha, Dae Sun Jo, Jin Han Kang

Journal: J. Korean Med. Sci.. 2015 May;30(5):612-6.

 

Effective and tolerable vaccination is an essential strategy to prevent Japanese encephalitis (JE) in endemic areas. Although the live attenuated SA 14-14-2 JE vaccine (LAJEV) has been widely used since its introduction, the systemic data of LAJEV was very rarely available in Korea. ...

Last Updated: 1 May 2015

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Can Rashtriya Bal Swasthya Karyakram give impetus and direction to Japanese encephalitis vaccination program?
 

Author(s): Tanigasalam Vasanthan, C Venkatesh

Journal: Indian Pediatr. 2015 Apr;52(4):348.

 

Last Updated: 1 May 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Japanese encephalitis" returned 25 free, full-text review articles on human participants. First 3 results:

Epidemiology of Japanese encephalitis in the Philippines: a systematic review.
 

Author(s): Anna Lena Lopez, Josephine G Aldaba, Vito G Roque, Amado O Tandoc, Ava Kristy Sy, Fe Esperanza Espino, Maricel DeQuiroz-Castro, Youngmee Jee, Maria Joyce Ducusin, Kimberley K Fox

Journal:

 

Japanese encephalitis virus (JEV) is an important cause of encephalitis in most of Asia, with high case fatality rates and often significant neurologic sequelae among survivors. The epidemiology of JE in the Philippines is not well defined. To support consideration of JE vaccine for ...

Last Updated: 21 Mar 2015

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Flaviviruses, an expanding threat in public health: focus on dengue, West Nile, and Japanese encephalitis virus.
 

Author(s): Carlo Amorin Daep, Jorge L Muñoz-Jordán, Eliseo Alberto Eugenin

Journal: J. Neurovirol.. 2014 Dec;20(6):539-60.

 

The flaviviruses dengue, West Nile, and Japanese encephalitis represent three major mosquito-borne viruses worldwide. These pathogens impact the lives of millions of individuals and potentially could affect non-endemic areas already colonized by mosquito vectors. Unintentional transport ...

Last Updated: 16 Dec 2014

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Vaccine strategies for the control and prevention of Japanese encephalitis in Mainland China, 1951-2011.
 

Author(s): Xiaoyan Gao, Xiaolong Li, Minghua Li, Shihong Fu, Huanyu Wang, Zhi Lu, Yuxi Cao, Ying He, Wuyang Zhu, Tingting Zhang, Ernest A Gould, Guodong Liang

Journal:

 

Japanese encephalitis (JE) is arguably one of the most serious viral encephalitis diseases worldwide. China has a long history of high prevalence of Japanese encephalitis, with thousands of cases reported annually and incidence rates often exceeding 15/100,000. In global terms, the ...

Last Updated: 15 Aug 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Immunogenicity of Co-administration of Measles and Japanese Encephalitis Vaccines
 

Status: Recruiting

Condition Summary: Measles; Rubella; Japanese Encephalitis

 

Last Updated: 29 Dec 2015

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Treatment of Japanese Encephalitis
 

Status: Recruiting

Condition Summary: Japanese Encephalitis

 

Last Updated: 8 Feb 2006

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Antibody Response of a Boosted Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in Children
 

Status: Not yet recruiting

Condition Summary: Japanese Encephalitis

 

Last Updated: 6 Oct 2013

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