Irritable Bowel Syndrome

Common Name(s)

Irritable Bowel Syndrome

Irritable Bowel Syndrome (IBS) is a common disease or condition that affects or aggravates a person’s colon or large intestine. Several symptoms accompany this syndrome, most notably diarrhea or constipation or alteration between the two. Other symptoms include abdominal pain, gas, and cramping. Though capable of causing great discomfort, IBS does not lead to more serious conditions such as colon cancer or ulcerative colitis. The exact cause of IBS is unknown.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Irritable Bowel Syndrome" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2013

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Digestive Disease National Coalition

The Digestive Disease National Coalition (DDNC) has provided national leadership on behalf of patient organizations, professional societies, and industry interested in the full spectrum of digestive disorders.

Last Updated: 29 Apr 2014

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 3 Oct 2013

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Irritable Bowel Syndrome Self Help and Support Group

The Irritable Bowel Syndrome Self Help and Support Group is a patient led and patient governed organization dedicated to helping everyone who suffers from IBS and other digestive health disorders, through patient communication, support, symptoms, causes, treatment, accurate information and education.

Last Updated: 12 Oct 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Irritable Bowel Syndrome" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2013

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Digestive Disease National Coalition

The Digestive Disease National Coalition (DDNC) has provided national leadership on behalf of patient organizations, professional societies, and industry interested in the full spectrum of digestive disorders.

http://ddnc.org/

Last Updated: 29 Apr 2014

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 3 Oct 2013

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Irritable Bowel Syndrome Self Help and Support Group

The Irritable Bowel Syndrome Self Help and Support Group is a patient led and patient governed organization dedicated to helping everyone who suffers from IBS and other digestive health disorders, through patient communication, support, symptoms, causes, treatment, accurate information and education.

http://www.ibsgroup.org

Last Updated: 12 Oct 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Irritable Bowel Syndrome" returned 749 free, full-text research articles on human participants. First 3 results:

Safety and tolerability of rifaximin for the treatment of irritable bowel syndrome without constipation: a pooled analysis of randomised, double-blind, placebo-controlled trials.
 

Author(s): P Schoenfeld, M Pimentel, L Chang, A Lembo, W D Chey, J Yu, C Paterson, E Bortey, W P Forbes

Journal: Aliment. Pharmacol. Ther.. 2014 May;39(10):1161-8.

 

The efficacy of rifaximin, a nonsystemic, gut-targeted antibiotic for reducing non-constipation-predominant irritable bowel syndrome (non-C IBS) symptoms, has been demonstrated in one phase 2b and two phase 3 randomised, double-blind, placebo-controlled trials, but detailed data about ...

Last Updated: 16 Apr 2014

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Economic burden of irritable bowel syndrome with constipation: a retrospective analysis of health care costs in a commercially insured population.
 

Author(s): Jalpa A Doshi, Qian Cai, Jessica L Buono, William M Spalding, Phil Sarocco, Hiangkiat Tan, Judith J Stephenson, Robyn T Carson

Journal: J Manag Care Pharm. 2014 Apr;20(4):382-90.

 

The prevalence of irritable bowel syndrome with constipation (IBS-C) is estimated to be between 4.3% and 5.2% among adults in the United States. Little is known about the health care resource utilization and costs associated with IBS-C.

Last Updated: 1 Apr 2014

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Chemotactic chemokines are important in the pathogenesis of irritable bowel syndrome.
 

Author(s): Charles Darkoh, Latoya Comer, Getie Zewdie, Stephen Harold, Ned Snyder, Herbert L Dupont

Journal:

 

Irritable bowel syndrome (IBS) is one of the most frequently diagnosed disorders, affecting about 20% of the general population in Western countries. This syndrome poses an enormous socio-economic burden, impairs the quality of life substantially, and increases healthcare costs. IBS ...

Last Updated: 26 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Irritable Bowel Syndrome" returned 168 free, full-text review articles on human participants. First 3 results:

[Correlation of the microbiota and intestinal mucosa in the pathophysiology and treatment of irritable bowel, irritable eye, and irritable mind syndrome].
 

Author(s): János Fehér, Illés Kovács, Elena Pacella, Zsolt Radák

Journal: Orv Hetil. 2014 Sep;155(37):1454-60.

 

Accumulating clinical evidence supports co-morbidity of irritable bowel, irritable eye and irritable mind symptoms. Furthermore, perturbation of the microbiota-host symbiosis (dysbiosis) is considered a common pathogenic mechanism connecting gastrointestinal, ocular and neuropsychiatric ...

Last Updated: 8 Sep 2014

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Is irritable bowel syndrome an organic disorder?
 

Author(s): Magdy El-Salhy, Doris Gundersen, Odd Helge Gilja, Jan Gunnar Hatlebakk, Trygve Hausken

Journal: World J. Gastroenterol.. 2014 Jan;20(2):384-400.

 

Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that is generally considered to be functional because there appears to be no associated anatomical defect. Stress and psychological factors are thought to play an important role in IBS. The gut neuroendocrine system ...

Last Updated: 27 Feb 2014

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Molecular basis of the irritable bowel syndrome.
 

Author(s): Anna Vaiopoulou, Georgios Karamanolis, Theodora Psaltopoulou, George Karatzias, Maria Gazouli

Journal: World J. Gastroenterol.. 2014 Jan;20(2):376-83.

 

Irritable bowel syndrome (IBS) is a functional disorder characterized by abdominal pain, discomfort and bloating. The pathophysiology of IBS is poorly understood, but the presence of psychosocial basis is now known. There is an increasing number of publications supporting the role ...

Last Updated: 27 Feb 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Irritable Bowel Syndrome and Food Sensitivity
 

Status: Recruiting

Condition Summary: Irritable Bowel Syndrome

 

Last Updated: 10 Jul 2014

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Irritable Bowel Syndrome and Lactibiane Tolerance
 

Status: Recruiting

Condition Summary: Irritable Bowel Syndrome

 

Last Updated: 6 Feb 2012

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Saccharomyces Boulardii in Diarrhea Dominant Irritable Bowel Syndrome
 

Status: Recruiting

Condition Summary: Irritable Bowel Syndrome

 

Last Updated: 12 Oct 2007

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