Irritable Bowel Syndrome

Common Name(s)

Irritable Bowel Syndrome

Irritable Bowel Syndrome (IBS) is a common disease or condition that affects or aggravates a person’s colon or large intestine. Several symptoms accompany this syndrome, most notably diarrhea or constipation or alteration between the two. Other symptoms include abdominal pain, gas, and cramping. Though capable of causing great discomfort, IBS does not lead to more serious conditions such as colon cancer or ulcerative colitis. The exact cause of IBS is unknown.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Irritable Bowel Syndrome" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2013

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Digestive Disease National Coalition

The Digestive Disease National Coalition (DDNC) has provided national leadership on behalf of patient organizations, professional societies, and industry interested in the full spectrum of digestive disorders.

Last Updated: 29 Apr 2014

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 3 Oct 2013

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Irritable Bowel Syndrome Self Help and Support Group

The Irritable Bowel Syndrome Self Help and Support Group is a patient led and patient governed organization dedicated to helping everyone who suffers from IBS and other digestive health disorders, through patient communication, support, symptoms, causes, treatment, accurate information and education.

Last Updated: 12 Oct 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Irritable Bowel Syndrome" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2013

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Digestive Disease National Coalition

The Digestive Disease National Coalition (DDNC) has provided national leadership on behalf of patient organizations, professional societies, and industry interested in the full spectrum of digestive disorders.

http://ddnc.org/

Last Updated: 29 Apr 2014

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 3 Oct 2013

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Irritable Bowel Syndrome Self Help and Support Group

The Irritable Bowel Syndrome Self Help and Support Group is a patient led and patient governed organization dedicated to helping everyone who suffers from IBS and other digestive health disorders, through patient communication, support, symptoms, causes, treatment, accurate information and education.

http://www.ibsgroup.org

Last Updated: 12 Oct 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Irritable Bowel Syndrome" returned 739 free, full-text research articles on human participants. First 3 results:

Safety and tolerability of rifaximin for the treatment of irritable bowel syndrome without constipation: a pooled analysis of randomised, double-blind, placebo-controlled trials.
 

Author(s): P Schoenfeld, M Pimentel, L Chang, A Lembo, W D Chey, J Yu, C Paterson, E Bortey, W P Forbes

Journal: Aliment. Pharmacol. Ther.. 2014 May;39(10):1161-8.

 

The efficacy of rifaximin, a nonsystemic, gut-targeted antibiotic for reducing non-constipation-predominant irritable bowel syndrome (non-C IBS) symptoms, has been demonstrated in one phase 2b and two phase 3 randomised, double-blind, placebo-controlled trials, but detailed data about ...

Last Updated: 16 Apr 2014

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Curative effect of warming kidney and fortifying spleen recipe on diarrhea-predominant irritable bowel syndrome.
 

Author(s): Xiaolan Su, Yanping Tang, Jing Zhang, Yuebin Dong, Wei Wei, Yibing Bai, Yong Liu

Journal: J Tradit Chin Med. 2013 Oct;33(5):615-9.

 

To observe the curative effect of a recipe for warming the kidney and fortifying the spleen on diarrhea-predominant irritable bowel syndrome (IBS-D).

Last Updated: 25 Mar 2014

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Treatment of constipation-predominant irritable bowel syndrome by focusing on the liver in terms of Traditional Chinese Medicine: a meta-analysis.
 

Author(s): Qianwen Li, Fengbin Liu, Zhengkun Hou, Di Luo

Journal: J Tradit Chin Med. 2013 Oct;33(5):562-71.

 

To assess the efficacy of Traditional Chinese Medicine (TCM) on constipation-predominant irritable bowel syndrome by focusing on the liver.

Last Updated: 25 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Irritable Bowel Syndrome" returned 162 free, full-text review articles on human participants. First 3 results:

The serotonin transporter gene polymorphism (5-HTTLPR) and irritable bowel syndrome: a meta-analysis of 25 studies.
 

Author(s): Zhi-Feng Zhang, Zhi-Jun Duan, Li-Xia Wang, Dong Yang, Gang Zhao, Lin Zhang

Journal:

 

The results of previous studies assessing the association between the 5-HTTLPR polymorphism of serotonin transporter gene and irritable bowel syndrome (IBS) are inconsistent. The aim of this study was to clarify the association between the 5-HTTLPR mutation and the presence of IBS ...

Last Updated: 18 Feb 2014

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Review article: Linaclotide for the management of irritable bowel syndrome with constipation.
 

Author(s): P Layer, V Stanghellini

Journal: Aliment. Pharmacol. Ther.. 2014 Feb;39(4):371-84.

 

Irritable bowel syndrome with constipation (IBS-C) represents a significant burden to patients and healthcare systems due to its prevalence and lack of successful symptomatic resolution with established treatment options. Linaclotide 290 μg has recently been approved by the European ...

Last Updated: 22 Jan 2014

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Challenges in management of irritable bowel syndrome in children.
 

Author(s): Siba Prosad Paul, Penny Barnard, Charlotte Bigwood, David C A Candy

Journal: Indian Pediatr. 2013 Dec;50(12):1137-43.

 

Irritable bowel syndrome (IBS) is a common cause of recurrent abdominal pain (RAP) in children and can be a debilitating experience for both child and family. Organic causes of RAP symptoms such as celiac and inflammatory bowel diseases should be excluded before a diagnosis of IBS ...

Last Updated: 13 Jan 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Irritable Bowel Syndrome and Food Sensitivity
 

Status: Recruiting

Condition Summary: Irritable Bowel Syndrome

 

Last Updated: 10 Jul 2014

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Irritable Bowel Syndrome and Lactibiane Tolerance
 

Status: Recruiting

Condition Summary: Irritable Bowel Syndrome

 

Last Updated: 6 Feb 2012

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Saccharomyces Boulardii in Diarrhea Dominant Irritable Bowel Syndrome
 

Status: Recruiting

Condition Summary: Irritable Bowel Syndrome

 

Last Updated: 12 Oct 2007

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