Iron Overload

Common Name(s)

Iron Overload

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Iron Overload" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Iron Overload" returned 423 free, full-text research articles on human participants. First 3 results:

Hemolytic anemia repressed hepcidin level without hepatocyte iron overload: lesson from Günther disease model.
 

Author(s): Sarah Millot, Constance Delaby, Boualem Moulouel, Thibaud Lefebvre, Nathalie Pilard, Nicolas Ducrot, Cécile Ged, Philippe Lettéron, Lucia de Franceschi, Jean Charles Deybach, Carole Beaumont, Laurent Gouya, Hubert De Verneuil, Saïd Lyoumi, Hervé Puy, Zoubida Karim

Journal: Haematologica. 2017 Feb;102(2):260-270.

 

Hemolysis occurring in hematologic diseases is often associated with an iron loading anemia. This iron overload is the result of a massive outflow of hemoglobin into the bloodstream, but the mechanism of hemoglobin handling has not been fully elucidated. Here, in a congenital erythropoietic ...

Last Updated: 1 Feb 2017

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Iron overload across the spectrum of non-transfusion-dependent thalassaemias: role of erythropoiesis, splenectomy and transfusions.
 

Author(s): John B Porter, Maria Domenica Cappellini, Antonis Kattamis, Vip Viprakasit, Khaled M Musallam, Zewen Zhu, Ali T Taher

Journal: Br. J. Haematol.. 2017 Jan;176(2):288-299.

 

Non-transfusion-dependent thalassaemias (NTDT) encompass a spectrum of anaemias rarely requiring blood transfusions. Increased iron absorption, driven by hepcidin suppression secondary to erythron expansion, initially causes intrahepatic iron overload. We examined iron metabolism ...

Last Updated: 5 Dec 2016

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Impact of Oxidative Stress in Premature Aging and Iron Overload in Hemodialysis Patients.
 

Author(s): Blanca Murillo-Ortiz, Joel Ramírez Emiliano, Wendy Ivett Hernández Vázquez, Sandra Martínez-Garza, Sergio Solorio-Meza, Froylán Albarrán-Tamayo, Edna Ramos-Rodríguez, Luis Benítez-Bribiesca

Journal: Oxid Med Cell Longev. 2016 ;2016():1578235.

 

Background. Increased oxidative stress is a well described feature of patients in hemodialysis. Their need for multiple blood transfusions and supplemental iron causes a significant iron overload that has recently been associated with increased oxidation of polyunsaturated lipids ...

Last Updated: 1 Nov 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Iron Overload" returned 81 free, full-text review articles on human participants. First 3 results:

Relationship between Hepatitis C Virus Infection and Iron Overload.
 

Author(s): Dong-Mei Zou, Wan-Ling Sun

Journal: Chin. Med. J.. 2017 Apr;130(7):866-871.

 

The aim of this study was to summarize the interactions between hepatitis C virus (HCV) infection and iron overload, and to understand the mechanisms of iron overload in chronic hepatitis C (CHC) and the role iron plays in HCV life cycle.

Last Updated: 27 Mar 2017

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Current Review of Iron Overload and Related Complications in Hematopoietic Stem Cell Transplantation.
 

Author(s): Erden Atilla, Selami K Toprak, Taner Demirer

Journal: Turk J Haematol. 2017 Mar;34(1):1-9.

 

Iron overload is an adverse prognostic factor for patients undergoing hematopoietic stem cell transplantation (HSCT). In the HSCT setting, pretransplant and early posttransplant ferritin and transferrin saturation were found to be highly elevated due to high transfusion requirements. ...

Last Updated: 13 Dec 2016

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The Role of Iron and Iron Overload in Chronic Liver Disease.
 

Author(s): Sandra Milic, Ivana Mikolasevic, Lidija Orlic, Edita Devcic, Nada Starcevic-Cizmarevic, Davor Stimac, Miljenko Kapovic, Smiljana Ristic

Journal:

 

The liver plays a major role in iron homeostasis; thus, in patients with chronic liver disease, iron regulation may be disturbed. Higher iron levels are present not only in patients with hereditary hemochromatosis, but also in those with alcoholic liver disease, nonalcoholic fatty ...

Last Updated: 23 Jun 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Estimation of Myocardial Iron Overload by 3 Tesla MRI in HFE Hereditary Haemochromatosis
 

Status: Recruiting

Condition Summary: Myocardial Iron Overload; HFE-Associated Hereditary Hemochromatosis

 

Last Updated: 11 Jul 2016

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Amlodipine as Adjuvant Treatment to Iron Chelation for Prevention of Cardiac Iron Overload in Thalassemia Patients
 

Status: Recruiting

Condition Summary: Beta-Thalassemia; Iron Overload

 

Last Updated: 24 Oct 2016

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Effect of Deferiprone on Oxidative-Stress and Iron-Overload in Low Risk Transfusion-Dependent MDS Patients
 

Status: Recruiting

Condition Summary: Myelodysplastic Syndrome With Low-grade Lesions; Iron Overload Due to Repeated Red Blood Cell Transfusions

 

Last Updated: 24 Apr 2017

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