Iron Overload

Common Name(s)

Iron Overload

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Iron Overload" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Iron Overload" returned 416 free, full-text research articles on human participants. First 3 results:

Effects of Iron Overload on the Activity of Na,K-ATPase and Lipid Profile of the Human Erythrocyte Membrane.
 

Author(s): Leilismara Sousa, Israel J P Garcia, Tamara G F Costa, Lilian N D Silva, Cristiane O Renó, Eneida S Oliveira, Cristiane Q Tilelli, Luciana L Santos, Vanessa F Cortes, Herica L Santos, Leandro A Barbosa

Journal:

 

Iron is an essential chemical element for human life. However, in some pathological conditions, such as hereditary hemochromatosis type 1 (HH1), iron overload induces the production of reactive oxygen species that may lead to lipid peroxidation and a change in the plasma-membrane ...

Last Updated: 22 Jul 2015

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Reassessment of Iron Biomarkers for Prediction of Dialysis Iron Overload: An MRI Study.
 

Author(s): Guy Rostoker, Mireille Griuncelli, Christelle Loridon, Théophile Magna, Gabrielle Machado, Gilles Drahi, Hervé Dahan, Philippe Janklewicz, Yves Cohen

Journal:

 

Iron overload among hemodialysis patients was previously considered rare but is now an increasingly recognized clinical situation. We analyzed correlations between iron biomarkers and the liver iron concentration (LIC) measured by magnetic resonance imaging (MRI), and examined their ...

Last Updated: 18 Jul 2015

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Both hepatic and body iron stores are increased in dysmetabolic iron overload syndrome. A case-control study.
 

Author(s): Caroline Jézéquel, Fabrice Lainé, Bruno Laviolle, Anita Kiani, Edouard Bardou-Jacquet, Yves Deugnier

Journal:

 

Hepatic iron is increased in dysmetabolic iron overload syndrome (DIOS). Whether this reflects elevated body iron stores is still debated. The study was aimed at assessing body iron stores in DIOS patients by calculating the amount of mobilized iron (AMI).

Last Updated: 2 Jun 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Iron Overload" returned 73 free, full-text review articles on human participants. First 3 results:

Use of magnetic resonance imaging to monitor iron overload.
 

Author(s): John C Wood

Journal: Hematol. Oncol. Clin. North Am.. 2014 Aug;28(4):747-64, vii.

 

Treatment of iron overload requires robust estimates of total-body iron burden and its response to iron chelation therapy. Compliance with chelation therapy varies considerably among patients, and individual reporting is notoriously unreliable. Even with perfect compliance, intersubject ...

Last Updated: 28 Jul 2014

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Impact of iron overload and potential benefit from iron chelation in low-risk myelodysplastic syndrome.
 

Author(s): Niraj Shenoy, Nishanth Vallumsetla, Eliezer Rachmilewitz, Amit Verma, Yelena Ginzburg

Journal: Blood. 2014 Aug;124(6):873-81.

 

Myelodysplastic syndromes (MDSs) are a group of heterogeneous clonal bone marrow disorders characterized by ineffective hematopoiesis, peripheral blood cytopenias, and potential for malignant transformation. Lower/intermediate-risk MDSs are associated with longer survival and high ...

Last Updated: 8 Aug 2014

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Role of iron overload-induced macrophage apoptosis in the pathogenesis of peritoneal endometriosis.
 

Author(s): Leila Pirdel, Manijeh Pirdel

Journal: Reproduction. 2014 Jun;147(6):R199-207.

 

This article presents an overview of the involvement of iron overload-induced nitric oxide (NO) overproduction in apoptosis of peritoneal macrophages of women with endometriosis. We have postulated that the peritoneal iron overload originated from retrograde menstruation or bleeding ...

Last Updated: 23 May 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Effects of Phlebotomy on Insulin Sensitivity in Insulin Resistance-associated Hepatic Iron Overload Patients
 

Status: Recruiting

Condition Summary: Insulin Resistance; Iron Overload

 

Last Updated: 11 Apr 2016

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High-Tc Susceptometer to Monitor Transfusional Iron Overload
 

Status: Recruiting

Condition Summary: Transfusional Iron Overload; Thalassemia Major; Sickle Cell Disease; Myelodysplastic Syndromes; Aplastic Anemia

 

Last Updated: 27 Feb 2016

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Estimation of Myocardial Iron Overload by 3 Tesla MRI in HFE Hereditary Haemochromatosis
 

Status: Recruiting

Condition Summary: Myocardial Iron Overload; HFE-Associated Hereditary Hemochromatosis

 

Last Updated: 21 Mar 2016

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