Iron Overload

Common Name(s)

Iron Overload

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Iron Overload" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Iron Overload" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Iron Overload" returned 448 free, full-text research articles on human participants. First 3 results:

Role of T1 mapping as a complementary tool to T2* for non-invasive cardiac iron overload assessment.
 

Author(s): Camilla Torlasco, Elena Cassinerio, Alberto Roghi, Andrea Faini, Marco Capecchi, Amna Abdel-Gadir, Cristina Giannattasio, Gianfranco Parati, James C Moon, Maria D Cappellini, Patrizia Pedrotti

Journal:

 

Iron overload-related heart failure is the principal cause of death in transfusion dependent patients, including those with Thalassemia Major. Linking cardiac siderosis measured by T2* to therapy improves outcomes. T1 mapping can also measure iron; preliminary data suggests it may ...

Last Updated: 31 Dec 1969

Go To URL
Improvement of chronic hepatitis B by iron chelation therapy in a patient with iron overload: A case report.
 

Author(s): Dong-Mei Zou, Dong-Dong Rong, Hong Zhao, Li Su, Wan-Ling Sun

Journal: Medicine (Baltimore). 2017 Dec;96(52):e9566.

 

This report describes seroconversion of hepatitis B surface antigen (HBsAg) in a patient with marked iron overload caused by chronic hepatitis B (CHB) after receiving iron chelation therapy and discusses the role of iron chelation therapy in CHB.

Last Updated: 31 Dec 1969

Go To URL
CCL2 is Upregulated by Decreased miR-122 Expression in Iron-Overload-Induced Hepatic Inflammation.
 

Author(s): Yuxiao Tang, Wentao Jia, Xiaowen Niu, Lusha Wu, Hui Shen, Lina Wang, Ruirui Qi, Changquan Ling, Min Li

Journal: Cell. Physiol. Biochem.. 2017 ;44(3):870-883.

 

Iron overload (IO) is accompanied by hepatic inflammation. The chemokine (C-C motif) ligand 2 (CCL2) mediates inflammation, and its overexpression is associated with IO. However, whether IO results in CCL2 overexpression in the liver and the underlying mechanisms are unclear.

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Iron Overload" returned 83 free, full-text review articles on human participants. First 3 results:

Deferasirox for managing iron overload in people with thalassaemia.
 

Author(s): Claudia Bollig, Lisa K Schell, Gerta Rücker, Roman Allert, Edith Motschall, Charlotte M Niemeyer, Dirk Bassler, Joerg J Meerpohl

Journal:

 

Thalassaemia is a hereditary anaemia due to ineffective erythropoiesis. In particular, people with thalassaemia major develop secondary iron overload resulting from regular red blood cell transfusions. Iron chelation therapy is needed to prevent long-term complications.Both deferoxamine ...

Last Updated: 31 Dec 1969

Go To URL
Relationship between Hepatitis C Virus Infection and Iron Overload.
 

Author(s): Dong-Mei Zou, Wan-Ling Sun

Journal: Chin. Med. J.. 2017 Apr;130(7):866-871.

 

The aim of this study was to summarize the interactions between hepatitis C virus (HCV) infection and iron overload, and to understand the mechanisms of iron overload in chronic hepatitis C (CHC) and the role iron plays in HCV life cycle.

Last Updated: 31 Dec 1969

Go To URL
Current Review of Iron Overload and Related Complications in Hematopoietic Stem Cell Transplantation.
 

Author(s): Erden Atilla, Selami K Toprak, Taner Demirer

Journal: Turk J Haematol. 2017 Mar;34(1):1-9.

 

Iron overload is an adverse prognostic factor for patients undergoing hematopoietic stem cell transplantation (HSCT). In the HSCT setting, pretransplant and early posttransplant ferritin and transferrin saturation were found to be highly elevated due to high transfusion requirements. ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Amlodipine as Adjuvant Treatment to Iron Chelation for Prevention of Cardiac Iron Overload in Thalassemia Patients
 

Status: Recruiting

Condition Summary: Beta-Thalassemia; Iron Overload

 

Last Updated: 24 Oct 2016

Go to URL
Effect of Deferiprone on Oxidative-Stress and Iron-Overload in Low Risk Transfusion-Dependent MDS Patients
 

Status: Recruiting

Condition Summary: Myelodysplastic Syndrome With Low-grade Lesions; Iron Overload Due to Repeated Red Blood Cell Transfusions

 

Last Updated: 24 Apr 2017

Go to URL
Study of MRI Monitoring in Patients With Aplastic Anemia and Low or Int-1 Risk of MDS Complicated With Iron Overload
 

Status: Not yet recruiting

Condition Summary: Aplastic Anemia; Dysmyelopoietic Syndromes; Iron Overload

 

Last Updated: 13 Jul 2016

Go to URL