Iron Overload

Common Name(s)

Iron Overload

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Iron Overload" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Iron Overload" returned 417 free, full-text research articles on human participants. First 3 results:

Impact of Oxidative Stress in Premature Aging and Iron Overload in Hemodialysis Patients.
 

Author(s): Blanca Murillo-Ortiz, Joel Ramírez Emiliano, Wendy Ivett Hernández Vázquez, Sandra Martínez-Garza, Sergio Solorio-Meza, Froylán Albarrán-Tamayo, Edna Ramos-Rodríguez, Luis Benítez-Bribiesca

Journal: Oxid Med Cell Longev. 2016 ;2016():1578235.

 

Background. Increased oxidative stress is a well described feature of patients in hemodialysis. Their need for multiple blood transfusions and supplemental iron causes a significant iron overload that has recently been associated with increased oxidation of polyunsaturated lipids ...

Last Updated: 1 Nov 2016

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Evaluation of QT parameters in patients of thalassaemia major with iron overload.
 

Author(s): Amna Faruqi, Syed Imran Ahmad, Syed Tousif Ahmed

Journal: J Pak Med Assoc. 2016 Jul;66(7):799-802.

 

To study QT parameters in Thalassaemia Major patients and their association with serum ferritin levels.

Last Updated: 18 Jul 2016

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Transfusional Iron Overload in a Cohort of Children with Sickle Cell Disease: Impact of Magnetic Resonance Imaging, Transfusion Method, and Chelation.
 

Author(s): Helen M Stanley, David F Friedman, Jennifer Webb, Janet L Kwiatkowski

Journal: Pediatr Blood Cancer. 2016 08;63(8):1414-8.

 

Transfusions prevent a number of complications of sickle cell disease (SCD), but cause inevitable iron loading. With magnetic resonance imaging (MRI), liver iron can be monitored noninvasively. Erythrocytapheresis can limit iron loading and oral chelation provides a more tolerable ...

Last Updated: 22 Jun 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Iron Overload" returned 79 free, full-text review articles on human participants. First 3 results:

Current Review of Iron Overload and Related Complications in Hematopoietic Stem Cell Transplantation.
 

Author(s): Erden Atilla, Selami K Toprak, Taner Demirer

Journal: Turk J Haematol. 2017 Mar;34(1):1-9.

 

Iron overload is an adverse prognostic factor for patients undergoing hematopoietic stem cell transplantation (HSCT). In the HSCT setting, pretransplant and early posttransplant ferritin and transferrin saturation were found to be highly elevated due to high transfusion requirements. ...

Last Updated: 13 Dec 2016

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Molecular pathogenesis and clinical consequences of iron overload in liver cirrhosis.
 

Author(s): Katarzyna Sikorska, Agnieszka Bernat, Anna Wroblewska

Journal: HBPD INT. 2016 Oct;15(5):461-479.

 

The liver, as the main iron storage compartment and the place of hepcidin synthesis, is the central organ involved in maintaining iron homeostasis in the body. Excessive accumulation of iron is an important risk factor in liver disease progression to cirrhosis and hepatocellular carcinoma. ...

Last Updated: 13 Oct 2016

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The Role of Iron and Iron Overload in Chronic Liver Disease.
 

Author(s): Sandra Milic, Ivana Mikolasevic, Lidija Orlic, Edita Devcic, Nada Starcevic-Cizmarevic, Davor Stimac, Miljenko Kapovic, Smiljana Ristic

Journal:

 

The liver plays a major role in iron homeostasis; thus, in patients with chronic liver disease, iron regulation may be disturbed. Higher iron levels are present not only in patients with hereditary hemochromatosis, but also in those with alcoholic liver disease, nonalcoholic fatty ...

Last Updated: 23 Jun 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Estimation of Myocardial Iron Overload by 3 Tesla MRI in HFE Hereditary Haemochromatosis
 

Status: Recruiting

Condition Summary: Myocardial Iron Overload; HFE-Associated Hereditary Hemochromatosis

 

Last Updated: 11 Jul 2016

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Amlodipine as Adjuvant Treatment to Iron Chelation for Prevention of Cardiac Iron Overload in Thalassemia Patients
 

Status: Recruiting

Condition Summary: Beta-Thalassemia; Iron Overload

 

Last Updated: 24 Oct 2016

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Effect of Deferiprone on Oxidative-Stress and Iron-Overload in Low Risk Transfusion-Dependent MDS Patients
 

Status: Recruiting

Condition Summary: Myelodysplastic Syndrome With Low-grade Lesions; Iron Overload Due to Repeated Red Blood Cell Transfusions

 

Last Updated: 24 Apr 2017

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