Iron Overload

Common Name(s)

Iron Overload

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Iron Overload" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Iron Overload" returned 418 free, full-text research articles on human participants. First 3 results:

Wild Edible Fruit of Prunus nepalensis Ser. (Steud), a Potential Source of Antioxidants, Ameliorates Iron Overload-Induced Hepatotoxicity and Liver Fibrosis in Mice.
 

Author(s): Dipankar Chaudhuri, Nikhil Baban Ghate, Sourav Panja, Abhishek Das, Nripendranath Mandal

Journal:

 

The antioxidant and restoration potentials of hepatic injury by Prunus nepalensis Ser. (Steud), a wild fruit plant from the Northeastern region of India, were investigated. The fruit extract (PNME) exhibited excellent antioxidant and reducing properties and also scavenged the 2,2-diphenyl-1-picrylhydrazyl ...

Last Updated: 4 Dec 2015

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Carriers of the Complex Allele HFE c.[187C>G;340+4T>C] Have Increased Risk of Iron Overload in São Miguel Island Population (Azores, Portugal).
 

Author(s): Claudia C Branco, Cidália T Gomes, Laura De Fez, Sara Bulhões, Maria José Brilhante, Tânia Pereirinha, Rita Cabral, Ana Catarina Rego, Cristina Fraga, António G Miguel, Gracinda Brasil, Paula Macedo, Luisa Mota-Vieira

Journal:

 

Iron overload is associated with acquired and genetic conditions, the most common being hereditary hemochromatosis (HH) type-I, caused by HFE mutations. Here, we conducted a hospital-based case-control study of 41 patients from the São Miguel Island (Azores, Portugal), six belonging ...

Last Updated: 27 Oct 2015

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Effects of Iron Overload on the Activity of Na,K-ATPase and Lipid Profile of the Human Erythrocyte Membrane.
 

Author(s): Leilismara Sousa, Israel J P Garcia, Tamara G F Costa, Lilian N D Silva, Cristiane O Renó, Eneida S Oliveira, Cristiane Q Tilelli, Luciana L Santos, Vanessa F Cortes, Herica L Santos, Leandro A Barbosa

Journal:

 

Iron is an essential chemical element for human life. However, in some pathological conditions, such as hereditary hemochromatosis type 1 (HH1), iron overload induces the production of reactive oxygen species that may lead to lipid peroxidation and a change in the plasma-membrane ...

Last Updated: 22 Jul 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Iron Overload" returned 73 free, full-text review articles on human participants. First 3 results:

Use of magnetic resonance imaging to monitor iron overload.
 

Author(s): John C Wood

Journal: Hematol. Oncol. Clin. North Am.. 2014 Aug;28(4):747-64, vii.

 

Treatment of iron overload requires robust estimates of total-body iron burden and its response to iron chelation therapy. Compliance with chelation therapy varies considerably among patients, and individual reporting is notoriously unreliable. Even with perfect compliance, intersubject ...

Last Updated: 28 Jul 2014

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Impact of iron overload and potential benefit from iron chelation in low-risk myelodysplastic syndrome.
 

Author(s): Niraj Shenoy, Nishanth Vallumsetla, Eliezer Rachmilewitz, Amit Verma, Yelena Ginzburg

Journal: Blood. 2014 Aug;124(6):873-81.

 

Myelodysplastic syndromes (MDSs) are a group of heterogeneous clonal bone marrow disorders characterized by ineffective hematopoiesis, peripheral blood cytopenias, and potential for malignant transformation. Lower/intermediate-risk MDSs are associated with longer survival and high ...

Last Updated: 8 Aug 2014

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Role of iron overload-induced macrophage apoptosis in the pathogenesis of peritoneal endometriosis.
 

Author(s): Leila Pirdel, Manijeh Pirdel

Journal: Reproduction. 2014 Jun;147(6):R199-207.

 

This article presents an overview of the involvement of iron overload-induced nitric oxide (NO) overproduction in apoptosis of peritoneal macrophages of women with endometriosis. We have postulated that the peritoneal iron overload originated from retrograde menstruation or bleeding ...

Last Updated: 23 May 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

High-Tc Susceptometer to Monitor Transfusional Iron Overload
 

Status: Recruiting

Condition Summary: Transfusional Iron Overload; Thalassemia Major; Sickle Cell Disease; Myelodysplastic Syndromes; Aplastic Anemia

 

Last Updated: 27 Feb 2016

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Estimation of Myocardial Iron Overload by 3 Tesla MRI in HFE Hereditary Haemochromatosis
 

Status: Recruiting

Condition Summary: Myocardial Iron Overload; HFE-Associated Hereditary Hemochromatosis

 

Last Updated: 21 Mar 2016

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MEPHISTO (Macrophage Phenotype In Metabolic Syndrome With Iron Overload)
 

Status: Recruiting

Condition Summary: Dysmetabolic Iron Overload Syndrome; Metabolic Syndrome X

 

Last Updated: 17 Feb 2014

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