Iron Overload

Common Name(s)

Iron Overload

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Iron Overload" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Iron Overload" returned 432 free, full-text research articles on human participants. First 3 results:

Hepatic iron overload is associated with hepatocyte apoptosis during Clonorchis sinensis infection.
 

Author(s): Su Han, Qiaoran Tang, Rui Chen, Yihong Li, Jing Shu, Xiaoli Zhang

Journal:

 

Hepatic iron overload has been implicated in many liver diseases; however, whether it is involved in clonorchiasis remains unknown. The purpose of this study is to investigate whether Clonorchis sinensis (C. sinensis) infection causes hepatic iron overload, analyze the relationship ...

Last Updated: 2 Aug 2017

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Prevalence of Fatty Liver Disease and Hepatic Iron Overload in a Northeastern German Population by Using Quantitative MR Imaging.
 

Author(s): Jens-Peter Kühn, Peter Meffert, Christian Heske, Marie-Luise Kromrey, Carsten O Schmidt, Birger Mensel, Henry Völzke, Markus M Lerch, Diego Hernando, Julia Mayerle, Scott B Reeder

Journal: Radiology. 2017 Sep;284(3):706-716.

 

Purpose To quantify liver fat and liver iron content by measurement of confounder-corrected proton density fat fraction (PDFF) and R2* and to identify clinical associations for fatty liver disease and liver iron overload and their prevalence in a large-scale population-based study. ...

Last Updated: 8 May 2017

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Cardiac iron overload in chronically transfused patients with thalassemia, sickle cell anemia, or myelodysplastic syndrome.
 

Author(s): Mariane de Montalembert, Jean-Antoine Ribeil, Valentine Brousse, Agnes Guerci-Bresler, Aspasia Stamatoullas, Jean-Pierre Vannier, Cécile Dumesnil, Agnès Lahary, Mohamed Touati, Krimo Bouabdallah, Marina Cavazzana, Emmanuelle Chauzit, Amandine Baptiste, Thibaud Lefebvre, Hervé Puy, Caroline Elie, Zoubida Karim, Olivier Ernst, Christian Rose

Journal:

 

The risk and clinical significance of cardiac iron overload due to chronic transfusion varies with the underlying disease. Cardiac iron overload shortens the life expectancy of patients with thalassemia, whereas its effect is unclear in those with myelodysplastic syndromes (MDS). ...

Last Updated: 3 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Iron Overload" returned 82 free, full-text review articles on human participants. First 3 results:

Relationship between Hepatitis C Virus Infection and Iron Overload.
 

Author(s): Dong-Mei Zou, Wan-Ling Sun

Journal: Chin. Med. J.. 2017 Apr;130(7):866-871.

 

The aim of this study was to summarize the interactions between hepatitis C virus (HCV) infection and iron overload, and to understand the mechanisms of iron overload in chronic hepatitis C (CHC) and the role iron plays in HCV life cycle.

Last Updated: 27 Mar 2017

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Current Review of Iron Overload and Related Complications in Hematopoietic Stem Cell Transplantation.
 

Author(s): Erden Atilla, Selami K Toprak, Taner Demirer

Journal: Turk J Haematol. 2017 Mar;34(1):1-9.

 

Iron overload is an adverse prognostic factor for patients undergoing hematopoietic stem cell transplantation (HSCT). In the HSCT setting, pretransplant and early posttransplant ferritin and transferrin saturation were found to be highly elevated due to high transfusion requirements. ...

Last Updated: 13 Dec 2016

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Iron overload and non-alcoholic fatty liver disease.
 

Author(s): Christian Datz, Elena Müller, Elmar Aigner

Journal: Minerva Endocrinol.. 2017 Jun;42(2):173-183.

 

Approximately one third of patients with non-alcoholic fatty liver disease (NAFLD) show signs of disturbed iron homeostasis as indicated by elevated serum ferritin with normal or mildly elevated transferrin saturation. Mild hepatic iron deposition is the typical histological finding ...

Last Updated: 11 Nov 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Amlodipine as Adjuvant Treatment to Iron Chelation for Prevention of Cardiac Iron Overload in Thalassemia Patients
 

Status: Recruiting

Condition Summary: Beta-Thalassemia; Iron Overload

 

Last Updated: 24 Oct 2016

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Effect of Deferiprone on Oxidative-Stress and Iron-Overload in Low Risk Transfusion-Dependent MDS Patients
 

Status: Recruiting

Condition Summary: Myelodysplastic Syndrome With Low-grade Lesions; Iron Overload Due to Repeated Red Blood Cell Transfusions

 

Last Updated: 24 Apr 2017

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Study of MRI Monitoring in Patients With Aplastic Anemia and Low or Int-1 Risk of MDS Complicated With Iron Overload
 

Status: Not yet recruiting

Condition Summary: Aplastic Anemia; Dysmyelopoietic Syndromes; Iron Overload

 

Last Updated: 13 Jul 2016

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