Iron Overload

Common Name(s)

Iron Overload

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Iron Overload" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Iron Overload" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Iron Overload" returned 427 free, full-text research articles on human participants. First 3 results:

Wild Edible Fruit of Prunus nepalensis Ser. (Steud), a Potential Source of Antioxidants, Ameliorates Iron Overload-Induced Hepatotoxicity and Liver Fibrosis in Mice.
 

Author(s): Dipankar Chaudhuri, Nikhil Baban Ghate, Sourav Panja, Abhishek Das, Nripendranath Mandal

Journal:

 

The antioxidant and restoration potentials of hepatic injury by Prunus nepalensis Ser. (Steud), a wild fruit plant from the Northeastern region of India, were investigated. The fruit extract (PNME) exhibited excellent antioxidant and reducing properties and also scavenged the 2,2-diphenyl-1-picrylhydrazyl ...

Last Updated: 4 Dec 2015

Go To URL
Carriers of the Complex Allele HFE c.[187C>G;340+4T>C] Have Increased Risk of Iron Overload in São Miguel Island Population (Azores, Portugal).
 

Author(s): Claudia C Branco, Cidália T Gomes, Laura De Fez, Sara Bulhões, Maria José Brilhante, Tânia Pereirinha, Rita Cabral, Ana Catarina Rego, Cristina Fraga, António G Miguel, Gracinda Brasil, Paula Macedo, Luisa Mota-Vieira

Journal:

 

Iron overload is associated with acquired and genetic conditions, the most common being hereditary hemochromatosis (HH) type-I, caused by HFE mutations. Here, we conducted a hospital-based case-control study of 41 patients from the São Miguel Island (Azores, Portugal), six belonging ...

Last Updated: 27 Oct 2015

Go To URL
Gradually-Deteriorating Liver Function due to Iron Overload Over Four Years after Allogeneic Stem Cell Transplantation.
 

Author(s): Hiroaki Tanaka, Chika Kawajiri, Shio Sakai, Yusuke Takeda, Takeharu Kawaguchi, Naoya Mimura, Emiko Sakaida, Chikako Ohwada, Masahiro Takeuchi, Shinichiro Hashimoto, Toshiyuki Takagi, Chiaki Nakaseko

Journal: J Clin Exp Hematop. 2015 ;55(2):109-12.

 

In allogeneic hematopoietic stem cell transplantation (allo-SCT) recipients with liver dysfunction, it is often difficult to determine the cause. Several cases of liver dysfunction may be interpreted as chronic graft versus host disease without a definitive diagnosis, resulting in ...

Last Updated: 22 Oct 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Iron Overload" returned 75 free, full-text review articles on human participants. First 3 results:

Phytochelators Intended for Clinical Use in Iron Overload, Other Diseases of Iron Imbalance and Free Radical Pathology.
 

Author(s): Christina N Kontoghiorghe, Annita Kolnagou, George J Kontoghiorghes

Journal:

 

Iron chelating drugs are primarily and widely used in the treatment of transfusional iron overload in thalassaemia and similar conditions. Recent in vivo and clinical studies have also shown that chelators, and in particular deferiprone, can be used effectively in many conditions ...

Last Updated: 27 Nov 2015

Go To URL
Use of magnetic resonance imaging to monitor iron overload.
 

Author(s): John C Wood

Journal: Hematol. Oncol. Clin. North Am.. 2014 Aug;28(4):747-64, vii.

 

Treatment of iron overload requires robust estimates of total-body iron burden and its response to iron chelation therapy. Compliance with chelation therapy varies considerably among patients, and individual reporting is notoriously unreliable. Even with perfect compliance, intersubject ...

Last Updated: 28 Jul 2014

Go To URL
The impact of chelation therapy on survival in transfusional iron overload: a meta-analysis of myelodysplastic syndrome.
 

Author(s): Arch G Mainous, Rebecca J Tanner, Mary M Hulihan, Mirna Amaya, Thomas D Coates

Journal: Br. J. Haematol.. 2014 Dec;167(5):720-3.

 

Last Updated: 14 Nov 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of MRI Monitoring in Patients With Aplastic Anemia and Low or Int-1 Risk of MDS Complicated With Iron Overload
 

Status: Not yet recruiting

Condition Summary: Aplastic Anemia; Dysmyelopoietic Syndromes; Iron Overload

 

Last Updated: 13 Jul 2016

Go to URL
Estimation of Myocardial Iron Overload by 3 Tesla MRI in HFE Hereditary Haemochromatosis
 

Status: Recruiting

Condition Summary: Myocardial Iron Overload; HFE-Associated Hereditary Hemochromatosis

 

Last Updated: 11 Jul 2016

Go to URL
MEPHISTO (Macrophage Phenotype In Metabolic Syndrome With Iron Overload)
 

Status: Recruiting

Condition Summary: Dysmetabolic Iron Overload Syndrome; Metabolic Syndrome X

 

Last Updated: 17 Feb 2014

Go to URL