Iron Overload

Common Name(s)

Iron Overload

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Iron Overload" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Iron Overload" returned 416 free, full-text research articles on human participants. First 3 results:

Impact of Oxidative Stress in Premature Aging and Iron Overload in Hemodialysis Patients.
 

Author(s): Blanca Murillo-Ortiz, Joel Ramírez Emiliano, Wendy Ivett Hernández Vázquez, Sandra Martínez-Garza, Sergio Solorio-Meza, Froylán Albarrán-Tamayo, Edna Ramos-Rodríguez, Luis Benítez-Bribiesca

Journal: Oxid Med Cell Longev. 2016 ;2016():1578235.

 

Background. Increased oxidative stress is a well described feature of patients in hemodialysis. Their need for multiple blood transfusions and supplemental iron causes a significant iron overload that has recently been associated with increased oxidation of polyunsaturated lipids ...

Last Updated: 1 Nov 2016

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Evaluation of QT parameters in patients of thalassaemia major with iron overload.
 

Author(s): Amna Faruqi, Syed Imran Ahmad, Syed Tousif Ahmed

Journal: J Pak Med Assoc. 2016 Jul;66(7):799-802.

 

To study QT parameters in Thalassaemia Major patients and their association with serum ferritin levels.

Last Updated: 18 Jul 2016

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Effect of Hereditary Hemochromatosis Gene H63D and C282Y Mutations on Iron Overload in Sickle Cell Disease Patients.
 

Author(s): Yunus Kasım Terzi, Tuğçe Bulakbaşı Balcı, Can Boğa, Zafer Koç, Zerrin Yılmaz Çelik, Hakan Özdoğu, Sema Karakuş, Feride İffet Şahin

Journal: Turk J Haematol. 2016 Dec;33(4):320-325.

 

Hemochromatosis is an autosomal recessive disease that is one of the most important reasons for iron overload. Sickle cell disease is a hemoglobinopathy that occurs as a result of a homozygous mutation in the hemoglobin gene. Erythrocyte transfusion is frequently used in the treatment ...

Last Updated: 20 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Iron Overload" returned 78 free, full-text review articles on human participants. First 3 results:

The Role of Iron and Iron Overload in Chronic Liver Disease.
 

Author(s): Sandra Milic, Ivana Mikolasevic, Lidija Orlic, Edita Devcic, Nada Starcevic-Cizmarevic, Davor Stimac, Miljenko Kapovic, Smiljana Ristic

Journal:

 

The liver plays a major role in iron homeostasis; thus, in patients with chronic liver disease, iron regulation may be disturbed. Higher iron levels are present not only in patients with hereditary hemochromatosis, but also in those with alcoholic liver disease, nonalcoholic fatty ...

Last Updated: 23 Jun 2016

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Iatrogenic Iron Overload in Dialysis Patients at the Beginning of the 21st Century.
 

Author(s): Guy Rostoker, Nosratola D Vaziri, Steven Fishbane

Journal: Drugs. 2016 May;76(7):741-57.

 

Iron overload used to be considered rare in hemodialysis patients but its clinical frequency is now increasingly realized. The liver is the main site of iron storage and the liver iron concentration (LIC) is closely correlated with total iron stores in patients with secondary hemosideroses ...

Last Updated: 27 Apr 2016

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Phytochelators Intended for Clinical Use in Iron Overload, Other Diseases of Iron Imbalance and Free Radical Pathology.
 

Author(s): Christina N Kontoghiorghe, Annita Kolnagou, George J Kontoghiorghes

Journal:

 

Iron chelating drugs are primarily and widely used in the treatment of transfusional iron overload in thalassaemia and similar conditions. Recent in vivo and clinical studies have also shown that chelators, and in particular deferiprone, can be used effectively in many conditions ...

Last Updated: 27 Nov 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Estimation of Myocardial Iron Overload by 3 Tesla MRI in HFE Hereditary Haemochromatosis
 

Status: Recruiting

Condition Summary: Myocardial Iron Overload; HFE-Associated Hereditary Hemochromatosis

 

Last Updated: 11 Jul 2016

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Amlodipine as Adjuvant Treatment to Iron Chelation for Prevention of Cardiac Iron Overload in Thalassemia Patients
 

Status: Recruiting

Condition Summary: Beta-Thalassemia; Iron Overload

 

Last Updated: 24 Oct 2016

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Effect of Deferiprone on Oxidative-Stress and Iron-Overload in Low Risk Transfusion-Dependent MDS Patients
 

Status: Recruiting

Condition Summary: Myelodysplastic Syndrome With Low-grade Lesions; Iron Overload Due to Repeated Red Blood Cell Transfusions

 

Last Updated: 13 Apr 2016

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