Iron deficiency anemia

Common Name(s)

Iron deficiency anemia

Iron deficiency anemia is the most common type of anemia. Anemia occurs when there are not enough healthy red blood cells. Red blood cells carry oxygen to the body’s tissues. Iron deficiency anemia is caused by our body not having enough iron. We get iron from our food, and also reuse (recycle) the iron from old red blood cells when they are taken from out of our system by the spleen. Iron is part of hemoglobin which is the molecule inside red blood cells which carries oxygen.

Symptoms may include extreme tiredness (fatigue), pale skin, weakness, shortness of breath, chest pain, frequent infections, headache, dizziness, cold hands and feet, soreness of your tongue, brittle nails, fast heartbeat, unusual craving for non-nutritive substances, such as ice or dirt, poor appetite, and uncomfortable tingling in your legs. Causes may include blood loss, a lack of iron in your diet, pregnancy, or an inability to absorb iron. Conditions which may make it difficult to absorb iron include Celiac disease and Crohn’s disease. Gastric bypass surgery or taking too many calcium based antacids may also decrease iron absorption.

Some individuals are at higher risk of developing iron deficiency anemia including women, infants and children, and frequent blood donors. Mild iron deficiency anemia doesn’t usually have complication. Severe iron deficiency anemia may lead to health problem including heart problems, problems during pregnancy, and growth problems. To diagnose iron deficiency anemia, your doctor will run blood work to determine your red blood cell size and color, hematocrit (the percentage of your blood volume made up of red blood cells), hemoglobin, and ferritin (protein that helps store iron in your body). Your doctor may recommend iron supplement to treat iron deficiency anemia. If you or someone you know has been diagnosed with iron deficiency anemia, talk to your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Iron deficiency anemia" for support, advocacy or research.

Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

Last Updated: 26 Dec 2012

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Iron deficiency anemia" for support, advocacy or research.

Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

http://www.jewishgenetics.org

Last Updated: 26 Dec 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Iron deficiency anemia" returned 339 free, full-text research articles on human participants. First 3 results:

Changes in the choroidal thickness in reproductive-aged women with iron-deficiency anemia.
 

Author(s): Erhan Yumusak, Aydin Ciftci, Selim Yalcin, Cemile Dayangan Sayan, Nevin Hande Dikel, Kemal Ornek

Journal:

 

The aim of this study was to investigate the potential significance of the central macular thickness (foveal thickness-FT) and choroidal thickness (CT) in the eyes of patients with iron-deficiency anemia, the most common form of the anemia, via enhanced-depth imaging optical coherence ...

Last Updated: 30 Dec 2015

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Safety and efficacy of ferumoxytol for the episodic treatment of iron deficiency anemia in patients with a history of unsatisfactory oral iron therapy: Results of a phase III, open-label, 6-month extension study.
 

Author(s): Saroj Vadhan-Raj, David C Ford, Naomi V Dahl, Kristine Bernard, Zhu Li, Lee F Allen, William E Strauss

Journal: Am. J. Hematol.. 2016 Feb;91(2):E3-5.

 

Last Updated: 23 Jan 2016

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Determinants of Iron Deficiency Anemia in a Cohort of Children Aged 6-71 Months Living in the Northeast of Minas Gerais, Brazil.
 

Author(s): Francisca Helena Calheiros Zanin, Camilo Adalton Mariano da Silva, Élido Bonomo, Romero Alves Teixeira, Cíntia Aparecida de Jesus Pereira, Karina Benatti dos Santos, Maria Arlene Fausto, Deborah Aparecida Negrão-Correa, Joel Alves Lamounier, Mariângela Carneiro

Journal:

 

Iron deficiency anemia is one of the most common nutritional disorders worldwide. The aim was to identify the prevalence and incidence of anemia in children and to identify predictors of this condition, including intestinal parasites, social, nutritional and environmental factors, ...

Last Updated: 8 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Iron deficiency anemia" returned 34 free, full-text review articles on human participants. First 3 results:

The status of iron absorption in older patients with iron deficiency anemia.
 

Author(s): K Silay, S Akinci, A Yalcin, T Guney, A Ulas, O Ozer, S Ozbek, I Dilek

Journal: Eur Rev Med Pharmacol Sci. 2015 Sep;19(17):3142-5.

 

The aim of this study is to evaluate the iron absorption status by using the oral iron absorption test (OIAT) in older patients with iron deficiency anemia (IDA) in comparison with younger patients.

Last Updated: 24 Sep 2015

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Management of Iron-Deficiency Anemia in Inflammatory Bowel Disease: A Systematic Review.
 

Author(s): Ole Haagen Nielsen, Mark Ainsworth, Mehmet Coskun, Günter Weiss

Journal: Medicine (Baltimore). 2015 Jun;94(23):e963.

 

Anemia is the most frequent complication of inflammatory bowel disease (IBD), but anemia, mostly due to iron deficiency, has long been neglected in these patients. The aim was to briefly present the pathophysiology, followed by a balanced overview of the different forms of iron replacement ...

Last Updated: 11 Jun 2015

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Multiple-Micronutrient Fortified Non-Dairy Beverage Interventions Reduce the Risk of Anemia and Iron Deficiency in School-Aged Children in Low-Middle Income Countries: A Systematic Review and Meta-Analysis (i-iv).
 

Author(s): Grant J Aaron, Daphna K Dror, Zhenyu Yang

Journal:

 

Multiple-micronutrient (MMN) fortification of beverages may be an effective option to deliver micronutrients to vulnerable populations. The aim of the present systematic review and meta-analysis is to evaluate the nutritional impacts of MMN fortified beverages in the context of low-middle ...

Last Updated: 26 May 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Trial of Captafer® vs. Oral Iron Sulfate in the Treatment of Iron Deficiency Anemia in Patients With IBD
 

Status: Recruiting

Condition Summary: Iron Deficiency Anemia; Inflammatory Bowel Disease

 

Last Updated: 12 May 2016

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Non-invasive Optical Detection of Iron Deficiency in Children
 

Status: Recruiting

Condition Summary: Iron Deficiency; Iron-deficiency Anemia; Child

 

Last Updated: 10 Jun 2016

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Last Updated: 9 Mar 2016

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