Iron deficiency anemia

Common Name(s)

Iron deficiency anemia

Iron deficiency anemia is the most common type of anemia. Anemia occurs when there are not enough healthy red blood cells. Red blood cells carry oxygen to the body’s tissues. Iron deficiency anemia is caused by our body not having enough iron. We get iron from our food, and also reuse (recycle) the iron from old red blood cells when they are taken from out of our system by the spleen. Iron is part of hemoglobin which is the molecule inside red blood cells which carries oxygen.

Symptoms may include extreme tiredness (fatigue), pale skin, weakness, shortness of breath, chest pain, frequent infections, headache, dizziness, cold hands and feet, soreness of your tongue, brittle nails, fast heartbeat, unusual craving for non-nutritive substances, such as ice or dirt, poor appetite, and uncomfortable tingling in your legs. Causes may include blood loss, a lack of iron in your diet, pregnancy, or an inability to absorb iron. Conditions which may make it difficult to absorb iron include Celiac disease and Crohn’s disease. Gastric bypass surgery or taking too many calcium based antacids may also decrease iron absorption.

Some individuals are at higher risk of developing iron deficiency anemia including women, infants and children, and frequent blood donors. Mild iron deficiency anemia doesn’t usually have complication. Severe iron deficiency anemia may lead to health problem including heart problems, problems during pregnancy, and growth problems. To diagnose iron deficiency anemia, your doctor will run blood work to determine your red blood cell size and color, hematocrit (the percentage of your blood volume made up of red blood cells), hemoglobin, and ferritin (protein that helps store iron in your body). Your doctor may recommend iron supplement to treat iron deficiency anemia. If you or someone you know has been diagnosed with iron deficiency anemia, talk to your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Iron deficiency anemia" for support, advocacy or research.

Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

Last Updated: 26 Dec 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Iron deficiency anemia" for support, advocacy or research.

Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

http://www.jewishgenetics.org

Last Updated: 26 Dec 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Iron deficiency anemia" returned 305 free, full-text research articles on human participants. First 3 results:

Cerebral venous sinus thrombosis with increased factor VIII activity in an adult with iron deficiency anemia.
 

Author(s): Hiroshi Yokota, Yuki Ida, Shinya Sugiura, Ken Sasaki, Hiroo Itoh

Journal: Neurol India. ;62(6):674-5.

 

Last Updated: 16 Jan 2015

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Iron deficiency anemia in an Egyptian pediatric population: a cross-sectional study.
 

Author(s): Mohamed M E Al Ghwass, Eman Fawzy Halawa, Samar Mohamed Sabry, Dalia Ahmed

Journal: Ann Afr Med. ;14(1):25-31.

 

The aim of this study is to assess the frequency of iron deficiency anemia (IDA) and associated sociodemographic factors among children between 6 months and 12 years of age.

Last Updated: 8 Jan 2015

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Clinical significance of C-reactive protein levels in predicting responsiveness to iron therapy in patients with inflammatory bowel disease and iron deficiency anemia.
 

Author(s): Tariq Iqbal, Jürgen Stein, Naveen Sharma, Stefanie Kulnigg-Dabsch, Senthil Vel, Christoph Gasche

Journal: Dig. Dis. Sci.. 2015 May;60(5):1375-81.

 

Iron deficiency anemia (IDA) is a common complication of inflammatory bowel disease (IBD). In clinical practice, many patients receive initial treatment with iron tablets although intravenous (i.v.) iron supplementation is often preferable.

Last Updated: 12 May 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Iron deficiency anemia" returned 31 free, full-text review articles on human participants. First 3 results:

Role of small bowel capsule endoscopy in the diagnosis and management of iron deficiency anemia in elderly: a comprehensive review of the current literature.
 

Author(s): Adnan Muhammad, Gitanjali Vidyarthi, Patrick Brady

Journal: World J. Gastroenterol.. 2014 Jul;20(26):8416-23.

 

Iron deficiency anemia (IDA) is common and often under recognized problem in the elderly. It may be the result of multiple factors including a bleeding lesion in the gastrointestinal tract. Twenty percent of elderly patients with IDA have a negative upper and lower endoscopy and two-thirds ...

Last Updated: 15 Jul 2014

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Iron refractory iron deficiency anemia.
 

Author(s): Luigia De Falco, Mayka Sanchez, Laura Silvestri, Caroline Kannengiesser, Martina U Muckenthaler, Achille Iolascon, Laurent Gouya, Clara Camaschella, Carole Beaumont

Journal: Haematologica. 2013 Jun;98(6):845-53.

 

Iron refractory iron deficiency anemia is a hereditary recessive anemia due to a defect in the TMPRSS6 gene encoding Matriptase-2. This protein is a transmembrane serine protease that plays an essential role in down-regulating hepcidin, the key regulator of iron homeostasis. Hallmarks ...

Last Updated: 4 Jun 2013

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Iron deficiency anemia: a common and curable disease.
 

Author(s): Jeffery L Miller

Journal:

 

Iron deficiency anemia arises when the balance of iron intake, iron stores, and the body's loss of iron are insufficient to fully support production of erythrocytes. Iron deficiency anemia rarely causes death, but the impact on human health is significant. In the developed world, ...

Last Updated: 2 Jul 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 17 Jul 2013

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Gastric Capsule Examination for Iron Deficiency Anaemia
 

Status: Recruiting

Condition Summary: Iron Deficiency Anemia

 

Last Updated: 18 May 2015

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