Iron deficiency anemia

Common Name(s)

Iron deficiency anemia

Iron deficiency anemia is the most common type of anemia. Anemia occurs when there are not enough healthy red blood cells. Red blood cells carry oxygen to the body’s tissues. Iron deficiency anemia is caused by our body not having enough iron. We get iron from our food, and also reuse (recycle) the iron from old red blood cells when they are taken from out of our system by the spleen. Iron is part of hemoglobin which is the molecule inside red blood cells which carries oxygen.

Symptoms may include extreme tiredness (fatigue), pale skin, weakness, shortness of breath, chest pain, frequent infections, headache, dizziness, cold hands and feet, soreness of your tongue, brittle nails, fast heartbeat, unusual craving for non-nutritive substances, such as ice or dirt, poor appetite, and uncomfortable tingling in your legs. Causes may include blood loss, a lack of iron in your diet, pregnancy, or an inability to absorb iron. Conditions which may make it difficult to absorb iron include Celiac disease and Crohn’s disease. Gastric bypass surgery or taking too many calcium based antacids may also decrease iron absorption.

Some individuals are at higher risk of developing iron deficiency anemia including women, infants and children, and frequent blood donors. Mild iron deficiency anemia doesn’t usually have complication. Severe iron deficiency anemia may lead to health problem including heart problems, problems during pregnancy, and growth problems. To diagnose iron deficiency anemia, your doctor will run blood work to determine your red blood cell size and color, hematocrit (the percentage of your blood volume made up of red blood cells), hemoglobin, and ferritin (protein that helps store iron in your body). Your doctor may recommend iron supplement to treat iron deficiency anemia. If you or someone you know has been diagnosed with iron deficiency anemia, talk to your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Iron deficiency anemia" for support, advocacy or research.

Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

Last Updated: 26 Dec 2012

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Iron deficiency anemia" for support, advocacy or research.

Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

http://www.jewishgenetics.org

Last Updated: 26 Dec 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Iron deficiency anemia" returned 348 free, full-text research articles on human participants. First 3 results:

Cost-Effectiveness of Price Subsidies on Fortified Packaged Infant Cereals in Reducing Iron Deficiency Anemia in 6-23-Month-Old-Children in Urban India.
 

Author(s): Rafael Plessow, Narendra Kumar Arora, Beatrice Brunner, Simon Wieser

Journal:

 

Iron deficiency anaemia (IDA) is a major public health problem in India and especially harmful in early childhood due to its impact on cognitive development and increased all-cause mortality. We estimate the cost-effectiveness of price subsidies on fortified packaged infant cereals ...

Last Updated: 14 Apr 2016

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High prevalence of iron deficiency anemia in infants attending a well-baby clinic in NorthWestern Saudi Arabia.
 

Author(s): Mahmood D Al-Mendalawi

Journal: Saudi Med J. 2016 Apr;37(4):466-7.

 

Last Updated: 7 Apr 2016

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THE PREVALENCE OF CELIAC DISEASE IN PATIENTS WITH IRON-DEFICIENCY ANEMIA IN CENTER AND SOUTH AREA OF IRAN.
 

Author(s): Mahmud Baghbanian, Ali Farahat, Hasan Ali Vahedian, Elham Sheyda, Mohamad Reza Zare-Khormizi

Journal: Arq Gastroenterol. 2015 Dec;52(4):278-82.

 

Celiac disease is an immune-mediated enteropathy due to a permanent sensitivity to gluten in genetically susceptible people. Iron-deficiency anemia is the most widely experienced anemia in humans. Iron-deficiency anemia additionally is a common extra intestinal manifestation of celiac disease.

Last Updated: 4 Feb 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Iron deficiency anemia" returned 37 free, full-text review articles on human participants. First 3 results:

Last Updated: 30 Nov 2015

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Discriminant indices for distinguishing thalassemia and iron deficiency in patients with microcytic anemia: a meta-analysis.
 

Author(s): Johannes J M L Hoffmann, Eloísa Urrechaga, Urko Aguirre

Journal: Clin. Chem. Lab. Med.. 2015 Nov;53(12):1883-94.

 

More than 40 mathematical indices have been proposed in the hematological literature for discriminating between iron deficiency anemia and thalassemia trait in subjects with microcytic red blood cells (RBCs). None of these discriminant indices is 100% sensitive and specific and also ...

Last Updated: 5 Nov 2015

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The status of iron absorption in older patients with iron deficiency anemia.
 

Author(s): K Silay, S Akinci, A Yalcin, T Guney, A Ulas, O Ozer, S Ozbek, I Dilek

Journal: Eur Rev Med Pharmacol Sci. 2015 Sep;19(17):3142-5.

 

The aim of this study is to evaluate the iron absorption status by using the oral iron absorption test (OIAT) in older patients with iron deficiency anemia (IDA) in comparison with younger patients.

Last Updated: 24 Sep 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Trial of Captafer® vs. Oral Iron Sulfate in the Treatment of Iron Deficiency Anemia in Patients With IBD
 

Status: Recruiting

Condition Summary: Iron Deficiency Anemia; Inflammatory Bowel Disease

 

Last Updated: 12 May 2016

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Last Updated: 19 Sep 2016

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Time to Relapse of Iron Deficiency Anaemia After Standard Treatment With The Intravenous Iron (Monofer®)
 

Status: Recruiting

Condition Summary: Iron Deficiency Anaemia

 

Last Updated: 1 Mar 2016

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