Intraocular melanoma

Common Name(s)

Intraocular melanoma

Intraocular melanoma is a cancer of the pigment-producing cells (melanocytes) in the middle layer of the eye, called the uveal tract.   The uveal tract has 3 main parts: (1) the choroid (the tissue layer filled with blood vessels); (2) the ciliary body (the ring of muscle tissue that changes the size of the pupil and the shape of the lens); and (3) the iris (the colored part of the eye). Most cases (90%) of intraocular melanoma develop in the choroid, called choroidal melanoma; the ciliary body is less commonly a site of origin, and the iris is the least common.  Each manifests with different clinical features and symptoms.  Treatment depends on the site of origin (choroid, ciliary body, or iris), size and location of the tumor, the age of the individual, and other factors.  
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Intraocular melanoma" for support, advocacy or research.

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Melanoma International Foundation

The mission of the Melanoma International Foundation is to develop personalized strategies with patients so they may live longer, better lives.

Last Updated: 29 Jun 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Intraocular melanoma" for support, advocacy or research.

Logo
Melanoma International Foundation

The mission of the Melanoma International Foundation is to develop personalized strategies with patients so they may live longer, better lives.

http://www.melanomainternational.org

Last Updated: 29 Jun 2015

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Intraocular melanoma" returned 19 free, full-text research articles on human participants. First 3 results:

Cost-effectiveness of proton beam therapy for intraocular melanoma.
 

Author(s): James P Moriarty, Bijan J Borah, Robert L Foote, Jose S Pulido, Nilay D Shah

Journal:

 

Proton beam therapy is a commonly accepted treatment for intraocular melanomas, but the literature is lacking in descriptions of patient preferences of clinical outcomes and economic impact. In addition, no economic evaluations have been published regarding the incremental cost-effectiveness ...

Last Updated: 21 May 2015

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The effects of intraocular silicone oil placement prior to iodine 125 brachytherapy for uveal melanoma: a clinical case series.
 

Author(s): Y Ahuja, K G Kapoor, R M Thomson, K M Furutani, R W Shultz, S L Stafford, S Dev, N E Abu-Yaghi, D Reynolds, J S Pulido

Journal: Eye (Lond). 2012 Nov;26(11):1487-9.

 

To investigate the role of silicone oil as an adjunct to iodine 125 ((125)I) brachytherapy in attenuating radiation dose and reducing radiation retinopathy.

Last Updated: 8 Nov 2012

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Prolapsed intraocular aspergilloma masquerading as malignant melanoma.
 

Author(s): Philip A Thomas, P Geraldine

Journal: Indian J Ophthalmol. 2004 Jun;52(2):172-3.

 

Last Updated: 30 Jul 2004

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Intraocular melanoma" returned 2 free, full-text review articles on human participants. First 3 results:

Risk factors for intraocular melanoma and occupational exposure.
 

Author(s): J M Lutz, I A Cree, A J Foss

Journal: Br J Ophthalmol. 1999 Oct;83(10):1190-3.

 

Last Updated: 11 Jan 2000

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Management of intraocular melanoma.
 

Author(s): W S Foulds

Journal: Br J Ophthalmol. 1990 Sep;74(9):559-60.

 

Last Updated: 11 Oct 1990

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 27 Sep 2011

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Intermittent Selumetinib for Uveal Melanoma
 

Status: Not yet recruiting

Condition Summary: Uveal Melanoma

 

Last Updated: 10 May 2016

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