Intraocular melanoma

Common Name(s)

Intraocular melanoma

Intraocular melanoma is a cancer of the pigment-producing cells (melanocytes) in the middle layer of the eye, called the uveal tract.   The uveal tract has 3 main parts: (1) the choroid (the tissue layer filled with blood vessels); (2) the ciliary body (the ring of muscle tissue that changes the size of the pupil and the shape of the lens); and (3) the iris (the colored part of the eye). Most cases (90%) of intraocular melanoma develop in the choroid, called choroidal melanoma; the ciliary body is less commonly a site of origin, and the iris is the least common.  Each manifests with different clinical features and symptoms.  Treatment depends on the site of origin (choroid, ciliary body, or iris), size and location of the tumor, the age of the individual, and other factors.  
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Intraocular melanoma" for support, advocacy or research.

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Melanoma International Foundation

The mission of the Melanoma International Foundation is to develop personalized strategies with patients so they may live longer, better lives.

Last Updated: 29 Jun 2015

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Intraocular melanoma" for support, advocacy or research.

Logo
Melanoma International Foundation

The mission of the Melanoma International Foundation is to develop personalized strategies with patients so they may live longer, better lives.

http://www.melanomainternational.org

Last Updated: 29 Jun 2015

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Intraocular melanoma" returned 20 free, full-text research articles on human participants. First 3 results:

Photoacoustic imaging features of intraocular tumors: Retinoblastoma and uveal melanoma.
 

Author(s): Guan Xu, Yafang Xue, Zeynep Gürsel Özkurt, Naziha Slimani, Zizhong Hu, Xueding Wang, Kewen Xia, Teng Ma, Qifa Zhou, Hakan Demirci

Journal:

 

The purpose of this study is to examine the capability of photoacoustic (PA) imaging (PAI) in assessing the unique molecular and architectural features in ocular tumors. A real-time PA and ultrasonography (US) parallel imaging system based on a research US platform was developed to ...

Last Updated: 23 Feb 2017

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IgG4-related intraocular inflammation masquerading as ciliary body melanoma in a young girl.
 

Author(s): Dipankar Das, Panna Deka, Geeta Verma, Ganesh Chandra Kuri, Harsha Bhattacharjee, Gayatri Bharali, Divya Pandey, Akanksha Koul, Bidisha Das, Apurba Deka

Journal: Indian J Ophthalmol. 2016 Aug;64(8):601-3.

 

Immunoglobulin G4 (IgG4-related diseases) affects various tissues and organs of the human body. Orbital, adnexal, and scleral inflammations were already reported in the medical literature. To the best of our knowledge, we report the first case of intraocular IgG4-associated inflammatory ...

Last Updated: 30 Sep 2016

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Cost-effectiveness of proton beam therapy for intraocular melanoma.
 

Author(s): James P Moriarty, Bijan J Borah, Robert L Foote, Jose S Pulido, Nilay D Shah

Journal:

 

Proton beam therapy is a commonly accepted treatment for intraocular melanomas, but the literature is lacking in descriptions of patient preferences of clinical outcomes and economic impact. In addition, no economic evaluations have been published regarding the incremental cost-effectiveness ...

Last Updated: 21 May 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Intraocular melanoma" returned 2 free, full-text review articles on human participants. First 3 results:

Risk factors for intraocular melanoma and occupational exposure.
 

Author(s): J M Lutz, I A Cree, A J Foss

Journal: Br J Ophthalmol. 1999 Oct;83(10):1190-3.

 

Last Updated: 11 Jan 2000

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Management of intraocular melanoma.
 

Author(s): W S Foulds

Journal: Br J Ophthalmol. 1990 Sep;74(9):559-60.

 

Last Updated: 11 Oct 1990

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Vorinostat in Patients With Class 2 High Risk Uveal Melanoma
 

Status: Not yet recruiting

Condition Summary: Uveal Melanoma

 

Last Updated: 31 Aug 2017

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Last Updated: 27 Sep 2011

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Dendritic Cells Plus Autologous Tumor RNA in Uveal Melanoma
 

Status: Recruiting

Condition Summary: Uveal Melanoma

 

Last Updated: 4 May 2017

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