Intraocular melanoma

Common Name(s)

Intraocular melanoma

Intraocular melanoma is a cancer of the pigment-producing cells (melanocytes) in the middle layer of the eye, called the uveal tract.   The uveal tract has 3 main parts: (1) the choroid (the tissue layer filled with blood vessels); (2) the ciliary body (the ring of muscle tissue that changes the size of the pupil and the shape of the lens); and (3) the iris (the colored part of the eye). Most cases (90%) of intraocular melanoma develop in the choroid, called choroidal melanoma; the ciliary body is less commonly a site of origin, and the iris is the least common.  Each manifests with different clinical features and symptoms.  Treatment depends on the site of origin (choroid, ciliary body, or iris), size and location of the tumor, the age of the individual, and other factors.  
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Intraocular melanoma" for support, advocacy or research.

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Melanoma International Foundation

The mission of the Melanoma International Foundation is to develop personalized strategies with patients so they may live longer, better lives.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Intraocular melanoma" for support, advocacy or research.

Logo
Melanoma International Foundation

The mission of the Melanoma International Foundation is to develop personalized strategies with patients so they may live longer, better lives.

http://www.melanomainternational.org

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Intraocular melanoma" returned 11 free, full-text research articles on human participants. First 3 results:

The effects of intraocular silicone oil placement prior to iodine 125 brachytherapy for uveal melanoma: a clinical case series.
 

Author(s): Y Ahuja, K G Kapoor, R M Thomson, K M Furutani, R W Shultz, S L Stafford, S Dev, N E Abu-Yaghi, D Reynolds, J S Pulido

Journal: Eye (Lond). 2012 Nov;26(11):1487-9.

 

To investigate the role of silicone oil as an adjunct to iodine 125 ((125)I) brachytherapy in attenuating radiation dose and reducing radiation retinopathy.

Last Updated: 8 Nov 2012

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Prolapsed intraocular aspergilloma masquerading as malignant melanoma.
 

Author(s): Philip A Thomas, P Geraldine

Journal: Indian J Ophthalmol. 2004 Jun;52(2):172-3.

 

Last Updated: 30 Jul 2004

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Prolonged survival after complete resection of metastases from intraocular melanoma.
 

Author(s): Michel Rivoire, Laurent Kodjikian, Sylvie NĂ©grier

Journal: Cancer. 2004 Jul;101(1):207-8; author reply 208.

 

Last Updated: 28 Jun 2004

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Intraocular melanoma" returned 2 free, full-text review articles on human participants. First 3 results:

Risk factors for intraocular melanoma and occupational exposure.
 

Author(s): J M Lutz, I A Cree, A J Foss

Journal: Br J Ophthalmol. 1999 Oct;83(10):1190-3.

 

Last Updated: 11 Jan 2000

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Management of intraocular melanoma.
 

Author(s): W S Foulds

Journal: Br J Ophthalmol. 1990 Sep;74(9):559-60.

 

Last Updated: 11 Oct 1990

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Adjuvant Sunitinib or Valproic Acid in High-Risk Patients With Uveal Melanoma
 

Status: Not yet recruiting

Condition Summary: Ciliary Body and Choroid Melanoma, Medium/Large Size; Ciliary Body and Choroid Melanoma, Small Size; Iris Melanoma; Stage I Intraocular Melanoma; Stage IIA Intraocular Melanoma; Stage IIB Intraocular Melanoma; Stage IIIA Intraocular Melanoma; Stage IIIB Intraocular Melanoma; Stage IIIC Intraocular Melanoma

 

Last Updated: 21 Aug 2014

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Trametinib With or Without GSK2141795 in Treating Patients With Metastatic Uveal Melanoma
 

Status: Recruiting

Condition Summary: Ciliary Body and Choroid Melanoma, Medium/Large Size; Ciliary Body and Choroid Melanoma, Small Size; Extraocular Extension Melanoma; Iris Melanoma; Metastatic Intraocular Melanoma; Recurrent Intraocular Melanoma; Stage IV Intraocular Melanoma

 

Last Updated: 23 Sep 2014

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New Biopsy Technique for Uveal Melanoma
 

Status: Recruiting

Condition Summary: Uveal Melanoma

 

Last Updated: 11 Aug 2014

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