Interstitial Lung Disease

Common Name(s)

Interstitial Lung Disease

Interstitial lung disease describes a group of disorders caused by damage to the lungs, which are the organs through which we breathe. This damage can cause difficulty breathing and low oxygen levels in the blood. Although the exact cause of interstitial lung disease is unknown, it can be triggered by various injuries resulting in scarring within the lungs. Normally, the body fixes the damaged lung tissue, but in patients with interstitial lung disease the repair process does not function properly, causing thick and scarred air sacs. Other risk factors include long-term exposure to hazardous materials, certain autoimmune diseases, such as rheumatoid arthritis, age, and smoking. Once the lung tissue starts scarring, medication can only slow down the damage but it cannot reverse the damage. Treatment may include radiation, chemotherapy drugs, heart medications or antibiotics.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial Lung Disease" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Interstitial Lung Disease" returned 520 free, full-text research articles on human participants. First 3 results:

Effects of rituximab in connective tissue disorders related interstitial lung disease.
 

Author(s): Gemma Lepri, Jerome Avouac, Paolo Airò, Francisco Anguita Santos, Silvia Bellando-Randone, Jelena Blagojevic, Francisco Garcia Hernàndez, Jose Antonio Gonzalez Nieto, Serena Guiducci, Suzana Jordan, Vidya Limaye, Britta Maurer, Albert Selva-O'Callaghan, Valeria Riccieri, Oliver Distler, Marco Matucci-Cerinic, Yannick Allanore

Journal: Clin. Exp. Rheumatol.. ;34 Suppl 100(5):181-185.

 

Interstitial lung disease (ILD) is a key prognostic factor in connective tissue disorders (CTDs). The aim of our study was to assess the changes in pulmonary functional tests (PFTs) in various CTDs, including anti-synthetase syndrome (SYN), systemic sclerosis (SSc) and mixed connective ...

Last Updated: 17 Oct 2016

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The First Successful Heart-Lung Transplant in a Korean Child with Humidifier Disinfectant-Associated Interstitial Lung Disease.
 

Author(s): Won Kyoung Jhang, Seong Jong Park, Eun Lee, Song I Yang, Soo Jong Hong, Ju-Hee Seo, Hyung-Young Kim, Jeong-Jun Park, Tae-Jin Yun, Hyeong Ryul Kim, Yong-Hee Kim, Dong Kwan Kim, Seung-Il Park, Sang-Oh Lee, Sang-Bum Hong, Tae-Sun Shim, In-Cheol Choi, Jinho Yu

Journal: J. Korean Med. Sci.. 2016 May;31(5):817-21.

 

From 2006 to 2011, an outbreak of a particular type of childhood interstitial lung disease occurred in Korea. The condition was intractable and progressed to severe respiratory failure, with a high mortality rate. Moreover, in several familial cases, the disease affected young women ...

Last Updated: 2 May 2016

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[Effect of prone position ventilation on respiratory mechanics and prognosis in patients with acute respiratory distress syndrome concurrent with interstitial lung disease].
 

Author(s): Qingwen Sun, Mangui Zhu, Yin Xi, Yuheng Yu, Xuesong Liu, Ling Sang, Yonghao Xu, Sibei Chen, Lingbo Nong, Weiqun He, Yuanda Xu, Yimin Li, Xiaoqing Liu

Journal: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2015 Oct;27(10):785-90.

 

To explore the effect of prone position ventilation (PPV) on respiratory mechanics and prognosis in patients with acute respiratory distress syndrome (ARDS) concurrent with interstitial lung disease (ILD).

Last Updated: 2 May 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Interstitial Lung Disease" returned 81 free, full-text review articles on human participants. First 3 results:

Management of interstitial lung disease associated with connective tissue disease.
 

Author(s): Stephen C Mathai, Sonye K Danoff

Journal:

 

The lung is a common site of complications of systemic connective tissue disease (CTD), and lung involvement can present in several ways. Interstitial lung disease (ILD) and pulmonary hypertension are the most common lung manifestations in CTD. Although it is generally thought that ...

Last Updated: 25 Feb 2016

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Managing interstitial lung disease detected on CT during lung cancer screening.
 

Author(s): Brian D Southern, Rachel G Scheraga, Ruchi Yadav

Journal: Cleve Clin J Med. 2016 Jan;83(1):55-65.

 

As long-term smokers undergo computed tomography (CT) to screen for lung cancer, cases of interstitial lung disease are being discovered incidentally. This article explains how to distinguish among the most common forms of interstitial lung disease in this situation and the role of ...

Last Updated: 14 Jan 2016

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Nonspecific interstitial pneumonia overlaps organizing pneumonia in lung-dominant connective tissue disease.
 

Author(s): Xue-Ren Li, Shou-Chun Peng, Lu-Qing Wei

Journal:

 

Here, we reported two cases of nonspecific interstitial pneumonia overlap organizing pneumonia (NSIP/OP) with lung-dominant connective tissue disease (LD-ILD). The first case is a patient with hands of chapped skin, right-sided pleuritic chest discomfort, weakness, positive ANA and ...

Last Updated: 30 Nov 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Specific Autoantibody Testing in Patients With Interstitial Lung Disease
 

Status: Recruiting

Condition Summary: Interstitial Lung Disease

 

Last Updated: 27 Oct 2016

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Last Updated: 25 Oct 2016

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Neuromuscular Electrical Stimulation in Patients With Interstitial Lung Disease
 

Status: Recruiting

Condition Summary: Interstitial Lung Disease

 

Last Updated: 10 Jul 2015

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