Interstitial Lung Disease

Common Name(s)

Interstitial Lung Disease

Interstitial lung disease describes a group of disorders caused by damage to the lungs, which are the organs through which we breathe. This damage can cause difficulty breathing and low oxygen levels in the blood. Although the exact cause of interstitial lung disease is unknown, it can be triggered by various injuries resulting in scarring within the lungs. Normally, the body fixes the damaged lung tissue, but in patients with interstitial lung disease the repair process does not function properly, causing thick and scarred air sacs. Other risk factors include long-term exposure to hazardous materials, certain autoimmune diseases, such as rheumatoid arthritis, age, and smoking. Once the lung tissue starts scarring, medication can only slow down the damage but it cannot reverse the damage. Treatment may include radiation, chemotherapy drugs, heart medications or antibiotics.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial Lung Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Interstitial Lung Disease" returned 384 free, full-text research articles on human participants. First 3 results:

Pemetrexed for advanced non-small cell lung cancer patients with interstitial lung disease.
 

Author(s): Motoyasu Kato, Takehito Shukuya, Fumiyuki Takahashi, Keita Mori, Kentaro Suina, Tetsuhiko Asao, Ryota Kanemaru, Yuichiro Honma, Keiko Muraki, Koji Sugano, Rina Shibayama, Ryo Koyama, Naoko Shimada, Kazuhisa Takahashi

Journal:

 

Non-small cell lung cancer (NSCLC) patients with interstitial lung disease (ILD) need to be approached carefully given the high incidence of pulmonary toxicity. Pemetrexed (PEM) is the key drug for the treatment of NSCLC. However, its safety, especially with respect to the exacerbation ...

Last Updated: 22 Jul 2014

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Low-dose oral imatinib in the treatment of systemic sclerosis interstitial lung disease unresponsive to cyclophosphamide: a phase II pilot study.
 

Author(s): Paolo Fraticelli, Barbara Gabrielli, Giovanni Pomponio, Gabriele Valentini, Silvia Bosello, Piersandro Riboldi, Maria Gerosa, Paola Faggioli, Roberto Giacomelli, Nicoletta Del Papa, Roberto Gerli, Claudio Lunardi, Stefano Bombardieri, Walter Malorni, Angelo Corvetta, Gianluca Moroncini, Armando Gabrielli,

Journal:

 

Pulmonary involvement represents a major cause of death of systemic sclerosis (SSc) patients. Recent data suggest that tyrosine kinase inhibitors, such as imatinib, may be a therapeutic option for SSc patients. However, preliminary published clinical trials were inconclusive about ...

Last Updated: 29 Aug 2014

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Parenchymal cryobiopsies for interstitial lung diseases: a step forward in disease management.
 

Author(s): Fabien Maldonado, Teng Moua, Joseph Skalski

Journal: Respirology. 2014 Aug;19(6):773-4.

 

Last Updated: 21 Jul 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Interstitial Lung Disease" returned 62 free, full-text review articles on human participants. First 3 results:

Respiratory bronchiolitis-interstitial lung disease.
 

Author(s): Alicja Sieminska, Krzysztof Kuziemski

Journal:

 

Respiratory bronchiolitis-associated interstitial lung disease (RB-ILD) is a rare, mild inflammatory pulmonary disorder that occurs almost exclusively in current or former heavy smokers, usually between the third and sixth decades, most likely with no gender predilection. The onset ...

Last Updated: 9 Sep 2014

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Review: interstitial lung disease associated with systemic sclerosis and idiopathic pulmonary fibrosis: how similar and distinct?
 

Author(s): Erica L Herzog, Aditi Mathur, Andrew M Tager, Carol Feghali-Bostwick, Frank Schneider, John Varga

Journal: Arthritis Rheumatol. 2014 Aug;66(8):1967-78.

 

Last Updated: 29 Jul 2014

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Interstitial lung disease: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases.
 

Author(s): Ivan O Rosas, Paul F Dellaripa, David J Lederer, Dinesh Khanna, Lisa R Young, Fernando J Martinez

Journal: Ann Am Thorac Soc. 2014 Apr;11 Suppl 3():S169-77.

 

Population-based, longitudinal studies spanning decades linking risk factors in childhood, adolescence and early adulthood to incident clinical interstitial lung disease (ILD) events in late adulthood have not been performed. In addition, no observational or randomized clinical trials ...

Last Updated: 23 Apr 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Role of Rheumatological Evaluation in the Management of Patients With Interstitial Lung Disease
 

Status: Recruiting

Condition Summary: Interstitial Lung Disease; Idiopathic Pulmonary Fibrosis; Connective Tissue Disease

 

Last Updated: 8 Apr 2015

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A Study of the Natural Progression of Interstitial Lung Disease (ILD)
 

Status: Recruiting

Condition Summary: Interstitial Lung Diseases; Idiopathic Pulmonary Fibrosis; Sarcoidosis

 

Last Updated: 13 Sep 2012

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Cyclophosphamide Systemic Sclerosis Associated Interstitial Lung Disease
 

Status: Recruiting

Condition Summary: Systemic Sclerosis; Scleroderma; Interstitial Lung Disease; Lung Fibrosis

 

Last Updated: 29 Apr 2015

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