Interstitial Lung Disease

Common Name(s)

Interstitial Lung Disease

Interstitial lung disease describes a group of disorders caused by damage to the lungs, which are the organs through which we breathe. This damage can cause difficulty breathing and low oxygen levels in the blood. Although the exact cause of interstitial lung disease is unknown, it can be triggered by various injuries resulting in scarring within the lungs. Normally, the body fixes the damaged lung tissue, but in patients with interstitial lung disease the repair process does not function properly, causing thick and scarred air sacs. Other risk factors include long-term exposure to hazardous materials, certain autoimmune diseases, such as rheumatoid arthritis, age, and smoking. Once the lung tissue starts scarring, medication can only slow down the damage but it cannot reverse the damage. Treatment may include radiation, chemotherapy drugs, heart medications or antibiotics.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial Lung Disease" for support, advocacy or research.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial Lung Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Interstitial Lung Disease" returned 376 free, full-text research articles on human participants. First 3 results:

Pemetrexed for advanced non-small cell lung cancer patients with interstitial lung disease.
 

Author(s): Motoyasu Kato, Takehito Shukuya, Fumiyuki Takahashi, Keita Mori, Kentaro Suina, Tetsuhiko Asao, Ryota Kanemaru, Yuichiro Honma, Keiko Muraki, Koji Sugano, Rina Shibayama, Ryo Koyama, Naoko Shimada, Kazuhisa Takahashi

Journal:

 

Non-small cell lung cancer (NSCLC) patients with interstitial lung disease (ILD) need to be approached carefully given the high incidence of pulmonary toxicity. Pemetrexed (PEM) is the key drug for the treatment of NSCLC. However, its safety, especially with respect to the exacerbation ...

Last Updated: 22 Jul 2014

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Prognostic factors for myositis-associated interstitial lung disease.
 

Author(s): Tomoyuki Fujisawa, Hironao Hozumi, Masato Kono, Noriyuki Enomoto, Dai Hashimoto, Yutaro Nakamura, Naoki Inui, Koshi Yokomura, Naoki Koshimizu, Mikio Toyoshima, Toshihiro Shirai, Kazumasa Yasuda, Hiroshi Hayakawa, Takafumi Suda

Journal:

 

Interstitial lung disease (ILD) is a common manifestation of polymyositis (PM), dermatomyositis (DM), and clinically amyopathic dermatomyositis (CADM); however, little is known about the factors influencing the prognosis for PM/DM/CADM-associated ILD. (PM/DM/CADM-ILD). The aim of ...

Last Updated: 9 Jun 2014

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Successful crizotinib rechallenge after crizotinib-induced interstitial lung disease.
 

Author(s): Motoko Tachihara, Kazuyuki Kobayashi, Yumiko Ishikawa, Suya Hori, Daisuke Tamura, Hiroshi Otera, Yasuhiro Funada, Yoshihiro Nishimura

Journal: Jpn. J. Clin. Oncol.. 2014 Aug;44(8):762-4.

 

We report the case of a 70-year-old Japanese male diagnosed with advanced lung adenocarcinoma harboring the echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase fusion gene. As soon as crizotinib was administered, tumor shrank immediately. On Day 25, he developed ...

Last Updated: 1 Aug 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Interstitial Lung Disease" returned 58 free, full-text review articles on human participants. First 3 results:

Review: interstitial lung disease associated with systemic sclerosis and idiopathic pulmonary fibrosis: how similar and distinct?
 

Author(s): Erica L Herzog, Aditi Mathur, Andrew M Tager, Carol Feghali-Bostwick, Frank Schneider, John Varga

Journal: Arthritis Rheumatol. 2014 Aug;66(8):1967-78.

 

Last Updated: 29 Jul 2014

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Diffuse interstitial lung disease as a first manifestation of Waldenström's macroglobulinemia: case report and review of the literature.
 

Author(s): Angélica Consuegra, Pedro J Marcos, Rubén Vázquez, Jorge Pombo, Guillermo Debén, Héctor Verea-Hernando

Journal: Arch. Bronconeumol.. 2014 Apr;50(4):151-3.

 

Waldenström's macroglobulinemia (WM) is a lymphoid malignancy characterized by infiltration, mainly of the bone marrow and lymph nodes, by small mature lymphocytes showing plasmacytoid differentiation, associated with an IgM monoclonal band, and, in general, a low degree of aggressiveness. ...

Last Updated: 2 Apr 2014

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Interstitial lung disease.
 

Author(s): Katerina M Antoniou, George A Margaritopoulos, Sara Tomassetti, Francesco Bonella, Ulrich Costabel, Venerino Poletti

Journal: Eur Respir Rev. 2014 Mar;23(131):40-54.

 

Interstitial lung diseases are a group of diffuse parenchymal lung disorders associated with substantial morbidity and mortality. Knowledge achieved in recent years has resulted in the publication of the new classification of idiopathic interstitial pneumonias, according to which ...

Last Updated: 4 Mar 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Role of Rheumatological Evaluation in the Management of Patients With Interstitial Lung Disease
 

Status: Recruiting

Condition Summary: Interstitial Lung Disease; Idiopathic Pulmonary Fibrosis; Connective Tissue Disease

 

Last Updated: 6 Oct 2013

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A Study of the Natural Progression of Interstitial Lung Disease (ILD)
 

Status: Recruiting

Condition Summary: Interstitial Lung Diseases; Idiopathic Pulmonary Fibrosis; Sarcoidosis

 

Last Updated: 13 Sep 2012

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Cyclophosphamide Systemic Sclerosis Associated Interstitial Lung Disease
 

Status: Recruiting

Condition Summary: Systemic Sclerosis; Scleroderma; Interstitial Lung Disease; Lung Fibrosis

 

Last Updated: 2 Jan 2014

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