Interstitial Lung Disease

Common Name(s)

Interstitial Lung Disease

Interstitial lung disease describes a group of disorders caused by damage to the lungs, which are the organs through which we breathe. This damage can cause difficulty breathing and low oxygen levels in the blood. Although the exact cause of interstitial lung disease is unknown, it can be triggered by various injuries resulting in scarring within the lungs. Normally, the body fixes the damaged lung tissue, but in patients with interstitial lung disease the repair process does not function properly, causing thick and scarred air sacs. Other risk factors include long-term exposure to hazardous materials, certain autoimmune diseases, such as rheumatoid arthritis, age, and smoking. Once the lung tissue starts scarring, medication can only slow down the damage but it cannot reverse the damage. Treatment may include radiation, chemotherapy drugs, heart medications or antibiotics.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial Lung Disease" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Interstitial Lung Disease" returned 478 free, full-text research articles on human participants. First 3 results:

An Atypical Clinical Course of Anti-MDA5 Antibody-positive Interstitial Lung Disease in a Patient with Three Deteriorations in 9 years.
 

Author(s): Yuki Sato, Kojiro Otsuka, Koji Tamai, Yuichiro Ono, Yasuhito Hamaguchi, Keisuke Tomii

Journal: Intern. Med.. 2017 ;56(3):341-346.

 

Anti-MDA5 antibody-positive patients with clinically amyopathic dermatomyositis (CADM) are at high risk of developing rapidly progressive interstitial lung disease (ILD), which is associated with a high mortality rate. Approximately half of the patients with ILD recover; however, ...

Last Updated: 3 Feb 2017

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Interstitial Lung Disease Induced by Pazopanib Treatment.
 

Author(s): Shotaro Ide, Noriho Sakamoto, Shintaro Hara, Atsuko Hara, Tomoyuki Kakugawa, Yoichi Nakamura, Yoji Futsuki, Koichi Izumikawa, Yuji Ishimatsu, Katsunori Yanagihara, Hiroshi Mukae

Journal: Intern. Med.. ;56(1):79-83.

 

Although pneumothorax has been reported to be a major pulmonary adverse event in patients treated with pazopanib, a multikinase inhibitor, drug-induced interstitial lung disease (DILD) has not been reported. A 74-year-old Japanese man who received pazopanib for the treatment of femoral ...

Last Updated: 4 Jan 2017

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Lung cancer development in patients with connective tissue disease-related interstitial lung disease: A retrospective observational study.
 

Author(s): Yasunori Enomoto, Naoki Inui, Katsuhiro Yoshimura, Koji Nishimoto, Kazutaka Mori, Masato Kono, Tomoyuki Fujisawa, Noriyuki Enomoto, Yutaro Nakamura, Toshihide Iwashita, Takafumi Suda

Journal: Medicine (Baltimore). 2016 Dec;95(50):e5716.

 

Previous studies have reported that patients with idiopathic pulmonary fibrosis occasionally develop lung cancer (LC). However, in connective tissue disease (CTD)-related interstitial lung disease (ILD), there are few data regarding the LC development. The aim of the present study ...

Last Updated: 15 Dec 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Interstitial Lung Disease" returned 81 free, full-text review articles on human participants. First 3 results:

[Fatal acute interstitial lung disease associated with docetaxel administration: about a case and review of the literature].
 

Author(s): Sami Aziz Brahmi, Seddik Youssef, Fatima Zahra Ziani, Said Afqir

Journal:

 

Docetaxel is a chemotherapeutic agent belonging to the taxane family. This drug is widely used to treat cancers. Interstitial lung disease is a rare but serious toxicity due to the high mortality risk. We report a case of a patient with breast cancer who had fatal acute interstitial ...

Last Updated: 19 Sep 2016

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Telomeropathies: an emerging spectrum of disorders with important implications for patients with interstitial lung disease.
 

Author(s): Giulia M Stella, Elisabetta Balestro, Donato Lacedonia, Simonetta Baraldo

Journal: Minerva Med.. 2016 Feb;107(1 Suppl 1):9-14.

 

Growing evidence demonstrates that a number of clinical disorders may be related to genetic defects in telomere replication and extension. Overall, these syndromes are referred to as "telomeropathies" or "telomere disorders/syndromes"; they are increasingly being identified. In adulthood, ...

Last Updated: 18 Jul 2016

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Management of interstitial lung disease associated with connective tissue disease.
 

Author(s): Stephen C Mathai, Sonye K Danoff

Journal:

 

The lung is a common site of complications of systemic connective tissue disease (CTD), and lung involvement can present in several ways. Interstitial lung disease (ILD) and pulmonary hypertension are the most common lung manifestations in CTD. Although it is generally thought that ...

Last Updated: 25 Feb 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Specific Autoantibody Testing in Patients With Interstitial Lung Disease
 

Status: Recruiting

Condition Summary: Interstitial Lung Disease

 

Last Updated: 27 Oct 2016

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Last Updated: 25 Oct 2016

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Neuromuscular Electrical Stimulation in Patients With Interstitial Lung Disease
 

Status: Recruiting

Condition Summary: Interstitial Lung Disease

 

Last Updated: 10 Jul 2015

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