Interstitial Lung Disease

Common Name(s)

Interstitial Lung Disease

Interstitial lung disease describes a group of disorders caused by damage to the lungs, which are the organs through which we breathe. This damage can cause difficulty breathing and low oxygen levels in the blood. Although the exact cause of interstitial lung disease is unknown, it can be triggered by various injuries resulting in scarring within the lungs. Normally, the body fixes the damaged lung tissue, but in patients with interstitial lung disease the repair process does not function properly, causing thick and scarred air sacs. Other risk factors include long-term exposure to hazardous materials, certain autoimmune diseases, such as rheumatoid arthritis, age, and smoking. Once the lung tissue starts scarring, medication can only slow down the damage but it cannot reverse the damage. Treatment may include radiation, chemotherapy drugs, heart medications or antibiotics.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial Lung Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Interstitial Lung Disease" returned 351 free, full-text research articles on human participants. First 3 results:

Adalimumab-induced acute interstitial lung disease in a patient with rheumatoid arthritis.
 

Author(s): Olívia Meira Dias, Daniel Antunes Silva Pereira, Bruno Guedes Baldi, André Nathan Costa, Rodrigo Abensur Athanazio, Ronaldo Adib Kairalla, Carlos Roberto Ribeiro Carvalho

Journal: J Bras Pneumol. ;40(1):77-81.

 

The use of immunobiological agents for the treatment of autoimmune diseases is increasing in medical practice. Anti-TNF therapies have been increasingly used in refractory autoimmune diseases, especially rheumatoid arthritis, with promising results. However, the use of such therapies ...

Last Updated: 14 Mar 2014

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Thoracic gas compression during forced expiration in patients with emphysema, interstitial lung disease and obesity.
 

Author(s): Päivi L Piirilä, Ulla Hodgson, Tomi Wuorimaa, Hans-Jürgen Smith, Anssi R A Sovijärvi

Journal:

 

Dynamic gas compression during forced expiration has an influence on conventional flow-volume spirometry results. The extent of gas compression in different pulmonary disorders remains obscure. Utilizing a flow plethysmograph we determined the difference between thoracic and mouth ...

Last Updated: 14 Mar 2014

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[Tegafur gimeracil oteracil potassium capsule induced acute interstitial lung disease: a case report].
 

Author(s): Fangfang Li, Yanfang Ju, Yin Guan, Hong Zhao

Journal: Zhongguo Fei Ai Za Zhi. 2014 Jan;17(1):53-6.

 

Last Updated: 8 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Interstitial Lung Disease" returned 52 free, full-text review articles on human participants. First 3 results:

Connective tissue disease related interstitial lung diseases and idiopathic pulmonary fibrosis: provisional core sets of domains and instruments for use in clinical trials.
 

Author(s): Lesley Ann Saketkoo, Shikha Mittoo, Dörte Huscher, Dinesh Khanna, Paul F Dellaripa, Oliver Distler, Kevin R Flaherty, Sid Frankel, Chester V Oddis, Christopher P Denton, Aryeh Fischer, Otylia M Kowal-Bielecka, Daphne LeSage, Peter A Merkel, Kristine Phillips, David Pittrow, Jeffrey Swigris, Katerina Antoniou, Robert P Baughman, Flavia V Castelino, Romy B Christmann, Lisa Christopher-Stine, Harold R Collard, Vincent Cottin, Sonye Danoff, Kristin B Highland, Laura Hummers, Ami A Shah, Dong Soon Kim, David A Lynch, Frederick W Miller, Susanna M Proudman, Luca Richeldi, Jay H Ryu, Nora Sandorfi, Catherine Sarver, Athol U Wells, Vibeke Strand, Eric L Matteson, Kevin K Brown, James R Seibold,

Journal: Thorax. 2014 May;69(5):428-36.

 

Clinical trial design in interstitial lung diseases (ILDs) has been hampered by lack of consensus on appropriate outcome measures for reliably assessing treatment response. In the setting of connective tissue diseases (CTDs), some measures of ILD disease activity and severity may ...

Last Updated: 14 Apr 2014

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The multifaceted aspects of interstitial lung disease in rheumatoid arthritis.
 

Author(s): Lorenzo Cavagna, Sara Monti, Vittorio Grosso, Nicola Boffini, Eva Scorletti, Gloria Crepaldi, Roberto Caporali

Journal: Biomed Res Int. 2013 ;2013():759760.

 

Interstitial lung disease (ILD) is a relevant extra-articular manifestation of rheumatoid arthritis (RA) that may occur either in early stages or as a complication of long-standing disease. RA related ILD (RA-ILD) significantly influences the quoad vitam prognosis of these patients. ...

Last Updated: 8 Nov 2013

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Immunosuppression for interstitial lung disease in systemic sclerosis.
 

Author(s): Susanna Cappelli, Serena Guiducci, Silvia Bellando Randone, Marco Matucci Cerinic

Journal: Eur Respir Rev. 2013 Sep;22(129):236-43.

 

The efficacy of immunosuppressors in the treatment of systemic sclerosis-interstitial lung disease is still matter of controversy. In this review we will analyse the evidence that immunosuppressors, despite not being able to reverse fibrotic changes, may help in slowing disease progression. ...

Last Updated: 2 Sep 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study of the Natural Progression of Interstitial Lung Disease (ILD)
 

Status: Recruiting

Condition Summary: Interstitial Lung Diseases; Idiopathic Pulmonary Fibrosis; Sarcoidosis

 

Last Updated: 13 Sep 2012

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The Role of Rheumatological Evaluation in the Management of Patients With Interstitial Lung Disease
 

Status: Recruiting

Condition Summary: Interstitial Lung Disease; Idiopathic Pulmonary Fibrosis; Connective Tissue Disease

 

Last Updated: 6 Oct 2013

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Cyclophosphamide Systemic Sclerosis Associated Interstitial Lung Disease
 

Status: Recruiting

Condition Summary: Systemic Sclerosis; Scleroderma; Interstitial Lung Disease; Lung Fibrosis

 

Last Updated: 2 Jan 2014

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