Interstitial Lung Disease

Common Name(s)

Interstitial Lung Disease

Interstitial lung disease describes a group of disorders caused by damage to the lungs, which are the organs through which we breathe. This damage can cause difficulty breathing and low oxygen levels in the blood. Although the exact cause of interstitial lung disease is unknown, it can be triggered by various injuries resulting in scarring within the lungs. Normally, the body fixes the damaged lung tissue, but in patients with interstitial lung disease the repair process does not function properly, causing thick and scarred air sacs. Other risk factors include long-term exposure to hazardous materials, certain autoimmune diseases, such as rheumatoid arthritis, age, and smoking. Once the lung tissue starts scarring, medication can only slow down the damage but it cannot reverse the damage. Treatment may include radiation, chemotherapy drugs, heart medications or antibiotics.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial Lung Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Interstitial Lung Disease" returned 512 free, full-text research articles on human participants. First 3 results:

[Effect of prone position ventilation on respiratory mechanics and prognosis in patients with acute respiratory distress syndrome concurrent with interstitial lung disease].
 

Author(s): Qingwen Sun, Mangui Zhu, Yin Xi, Yuheng Yu, Xuesong Liu, Ling Sang, Yonghao Xu, Sibei Chen, Lingbo Nong, Weiqun He, Yuanda Xu, Yimin Li, Xiaoqing Liu

Journal: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2015 Oct;27(10):785-90.

 

To explore the effect of prone position ventilation (PPV) on respiratory mechanics and prognosis in patients with acute respiratory distress syndrome (ARDS) concurrent with interstitial lung disease (ILD).

Last Updated: 2 May 2016

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Computer-Aided Tomographic Analysis of Interstitial Lung Disease (ILD) in Patients with Systemic Sclerosis (SSc). Correlation with Pulmonary Physiologic Tests and Patient-Centred Measures of Perceived Dyspnea and Functional Disability.
 

Author(s): Fausto Salaffi, Marina Carotti, Eleonora Di Donato, Marco Di Carlo, Luca Ceccarelli, Gianmarco Giuseppetti

Journal:

 

This study was designed (a) to evaluate an improved quantitative lung fibrosis score based on a computer-aided diagnosis (CaM) system in patients with systemic sclerosis (SSc),-related interstitial lung disease (SSc-ILD), (b) to investigate the relationship between physiologic parameters ...

Last Updated: 2 Mar 2016

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Surfactant Protein C-associated interstitial lung disease; three different phenotypes of the same SFTPC mutation.
 

Author(s): Teresa Salerno, Donatella Peca, Laura Menchini, Alessandra Schiavino, Renata Boldrini, Fulvio Esposito, Olivier Danhaive, Renato Cutrera

Journal:

 

Monoallelic mutations of the Surfactant Protein C gene (SFTPC) are associated with Interstitial Lung Disease in children. I73T is the most common mutation, accounting for 30 % of all cases reported.

Last Updated: 1 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Interstitial Lung Disease" returned 81 free, full-text review articles on human participants. First 3 results:

Management of interstitial lung disease associated with connective tissue disease.
 

Author(s): Stephen C Mathai, Sonye K Danoff

Journal:

 

The lung is a common site of complications of systemic connective tissue disease (CTD), and lung involvement can present in several ways. Interstitial lung disease (ILD) and pulmonary hypertension are the most common lung manifestations in CTD. Although it is generally thought that ...

Last Updated: 25 Feb 2016

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Nonspecific interstitial pneumonia overlaps organizing pneumonia in lung-dominant connective tissue disease.
 

Author(s): Xue-Ren Li, Shou-Chun Peng, Lu-Qing Wei

Journal:

 

Here, we reported two cases of nonspecific interstitial pneumonia overlap organizing pneumonia (NSIP/OP) with lung-dominant connective tissue disease (LD-ILD). The first case is a patient with hands of chapped skin, right-sided pleuritic chest discomfort, weakness, positive ANA and ...

Last Updated: 30 Nov 2015

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Interstitial lung disease in systemic sclerosis: where do we stand?
 

Author(s): Susanna Cappelli, Silvia Bellando Randone, Gianna Camiciottoli, Amato De Paulis, Serena Guiducci, Marco Matucci-Cerinic

Journal: Eur Respir Rev. 2015 Sep;24(137):411-9.

 

Interstitial lung disease (ILD) is common in systemic sclerosis (SSc) patients and despite recent advances in the treatment is, at present, the major cause of death. Today, an early diagnosis of ILD is possible, and is mandatory to improve the prognosis of the disease. Pulmonary function ...

Last Updated: 1 Sep 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Specific Autoantibody Testing in Patients With Interstitial Lung Disease
 

Status: Recruiting

Condition Summary: Interstitial Lung Disease

 

Last Updated: 27 Oct 2016

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Last Updated: 25 Oct 2016

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Neuromuscular Electrical Stimulation in Patients With Interstitial Lung Disease
 

Status: Recruiting

Condition Summary: Interstitial Lung Disease

 

Last Updated: 10 Jul 2015

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