Interstitial Lung Disease

Common Name(s)

Interstitial Lung Disease

Interstitial lung disease describes a group of disorders caused by damage to the lungs, which are the organs through which we breathe. This damage can cause difficulty breathing and low oxygen levels in the blood. Although the exact cause of interstitial lung disease is unknown, it can be triggered by various injuries resulting in scarring within the lungs. Normally, the body fixes the damaged lung tissue, but in patients with interstitial lung disease the repair process does not function properly, causing thick and scarred air sacs. Other risk factors include long-term exposure to hazardous materials, certain autoimmune diseases, such as rheumatoid arthritis, age, and smoking. Once the lung tissue starts scarring, medication can only slow down the damage but it cannot reverse the damage. Treatment may include radiation, chemotherapy drugs, heart medications or antibiotics.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial Lung Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Interstitial Lung Disease" returned 400 free, full-text research articles on human participants. First 3 results:

Long-term follow-up of patients with scleroderma interstitial lung disease treated with intravenous cyclophosphamide pulse therapy: a single-center experience.
 

Author(s): Alexandra Balbir-Gurman, Mordechai Yigla, Ludmila Guralnik, Emilia Hardak, Anna Solomonov, Alexander P Rozin, Kohava Toledano, Amir Dagan, Rema Bishara, Doron Markovits, Menahem A Nahir, Yolanda Braun-Moscovici

Journal: Isr. Med. Assoc. J.. 2015 Mar;17(3):150-6.

 

Scleroderma lung disease (ILD-SSc) is treated mainly with cyclophosphamide (CYC). The effectiveness of CYC was judged after 12-24 months in most reports.

Last Updated: 7 May 2015

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Early pulmonary involvement of anti-CADM-140 autoantibody-positive rapidly progressive interstitial lung disease preceding typical cutaneous symptoms.
 

Author(s): Koji Tamai, Ryo Tachikawa, Kyoko Otsuka, Hiroyuki Ueda, Yuji Hosono, Keisuke Tomii

Journal: Intern. Med.. 2014 ;53(21):2515-9.

 

We herein report a patient with clinically amyopathic dermatomyositis (CADM) who developed anti-CADM-140 autoantibody in association with rapidly progressive interstitial lung disease (RP-ILD). Chest high-resolution computed tomography (HRCT) revealed early pulmonary involvement preceding ...

Last Updated: 4 Nov 2014

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Cutaneous ulceration in dermatomyositis: association with anti-melanoma differentiation-associated gene 5 antibodies and interstitial lung disease.
 

Author(s): Neera S Narang, Livia Casciola-Rosen, Shufeng Li, Lorinda Chung, David F Fiorentino

Journal: Arthritis Care Res (Hoboken). 2015 May;67(5):667-72.

 

To identify clinical and serologic correlates of cutaneous ulcers in dermatomyositis (DM).

Last Updated: 27 Apr 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Interstitial Lung Disease" returned 64 free, full-text review articles on human participants. First 3 results:

Respiratory disease and respiratory physiology: putting lung function into perspective interstitial lung disease.
 

Author(s): Norbert Berend

Journal: Respirology. 2014 Oct;19(7):952-9.

 

The interstitial lung diseases pathologically involve the pulmonary interstitium but may also involve the airways, pleura and pulmonary circulation. They may be idiopathic, be part of other conditions, or be related to drug or environmental exposures. This review will focus on diagnostic ...

Last Updated: 11 Sep 2014

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Respiratory bronchiolitis-interstitial lung disease.
 

Author(s): Alicja Sieminska, Krzysztof Kuziemski

Journal:

 

Respiratory bronchiolitis-associated interstitial lung disease (RB-ILD) is a rare, mild inflammatory pulmonary disorder that occurs almost exclusively in current or former heavy smokers, usually between the third and sixth decades, most likely with no gender predilection. The onset ...

Last Updated: 9 Sep 2014

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Review: interstitial lung disease associated with systemic sclerosis and idiopathic pulmonary fibrosis: how similar and distinct?
 

Author(s): Erica L Herzog, Aditi Mathur, Andrew M Tager, Carol Feghali-Bostwick, Frank Schneider, John Varga

Journal: Arthritis Rheumatol. 2014 Aug;66(8):1967-78.

 

Last Updated: 29 Jul 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Interstitial Lung Diseases in the Veterans Administration
 

Status: Not yet recruiting

Condition Summary: Interstitial Lung Disease

 

Last Updated: 22 Jun 2015

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The Role of Rheumatological Evaluation in the Management of Patients With Interstitial Lung Disease
 

Status: Recruiting

Condition Summary: Interstitial Lung Disease; Idiopathic Pulmonary Fibrosis; Connective Tissue Disease

 

Last Updated: 8 Apr 2015

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A Study of the Natural Progression of Interstitial Lung Disease (ILD)
 

Status: Recruiting

Condition Summary: Interstitial Lung Diseases; Idiopathic Pulmonary Fibrosis; Sarcoidosis

 

Last Updated: 13 Sep 2012

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