Interstitial Lung Disease

Common Name(s)

Interstitial Lung Disease

Interstitial lung disease describes a group of disorders caused by damage to the lungs, which are the organs through which we breathe. This damage can cause difficulty breathing and low oxygen levels in the blood. Although the exact cause of interstitial lung disease is unknown, it can be triggered by various injuries resulting in scarring within the lungs. Normally, the body fixes the damaged lung tissue, but in patients with interstitial lung disease the repair process does not function properly, causing thick and scarred air sacs. Other risk factors include long-term exposure to hazardous materials, certain autoimmune diseases, such as rheumatoid arthritis, age, and smoking. Once the lung tissue starts scarring, medication can only slow down the damage but it cannot reverse the damage. Treatment may include radiation, chemotherapy drugs, heart medications or antibiotics.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial Lung Disease" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Interstitial Lung Disease" returned 502 free, full-text research articles on human participants. First 3 results:

Computer-Aided Tomographic Analysis of Interstitial Lung Disease (ILD) in Patients with Systemic Sclerosis (SSc). Correlation with Pulmonary Physiologic Tests and Patient-Centred Measures of Perceived Dyspnea and Functional Disability.
 

Author(s): Fausto Salaffi, Marina Carotti, Eleonora Di Donato, Marco Di Carlo, Luca Ceccarelli, Gianmarco Giuseppetti

Journal:

 

This study was designed (a) to evaluate an improved quantitative lung fibrosis score based on a computer-aided diagnosis (CaM) system in patients with systemic sclerosis (SSc),-related interstitial lung disease (SSc-ILD), (b) to investigate the relationship between physiologic parameters ...

Last Updated: 2 Mar 2016

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Interstitial lung disease associated with gemcitabine: A Japanese retrospective cohort study.
 

Author(s): Tsuyoshi Hamada, Hideo Yasunaga, Yousuke Nakai, Hiroyuki Isayama, Hiroki Matsui, Kiyohide Fushimi, Kazuhiko Koike

Journal: Respirology. 2016 Feb;21(2):338-43.

 

Interstitial lung disease (ILD) is a widely recognized adverse consequence of gemcitabine administration, but data on gemcitabine-associated ILD are limited. This study aimed to elucidate the incidence and risk factors for this adverse event.

Last Updated: 18 Jan 2016

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Increased Risks of Spontaneous Bacterial Peritonitis and Interstitial Lung Disease in Primary Biliary Cirrhosis Patients With Concomitant Sjögren Syndrome.
 

Author(s): Chun-Ting Chen, Yu-Chen Tseng, Chih-Wei Yang, Hsuan-Hwai Lin, Peng-Jen Chen, Tien-Yu Huang, Yu-Lueng Shih, Wei-Kuo Chang, Tsai-Yuan Hsieh, Heng-Cheng Chu

Journal: Medicine (Baltimore). 2016 Jan;95(2):e2537.

 

The incidence of Sjögren syndrome (SS) in primary biliary cirrhosis (PBC) patients is high. The influence of SS on the clinical outcomes of PBC patients, however, remains unclear. Our study retrospectively collected data on PBC-only patients and PBC patients with concomitant SS (PBC-SS) ...

Last Updated: 15 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Interstitial Lung Disease" returned 80 free, full-text review articles on human participants. First 3 results:

Management of interstitial lung disease associated with connective tissue disease.
 

Author(s): Stephen C Mathai, Sonye K Danoff

Journal:

 

The lung is a common site of complications of systemic connective tissue disease (CTD), and lung involvement can present in several ways. Interstitial lung disease (ILD) and pulmonary hypertension are the most common lung manifestations in CTD. Although it is generally thought that ...

Last Updated: 25 Feb 2016

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Nonspecific interstitial pneumonia overlaps organizing pneumonia in lung-dominant connective tissue disease.
 

Author(s): Xue-Ren Li, Shou-Chun Peng, Lu-Qing Wei

Journal:

 

Here, we reported two cases of nonspecific interstitial pneumonia overlap organizing pneumonia (NSIP/OP) with lung-dominant connective tissue disease (LD-ILD). The first case is a patient with hands of chapped skin, right-sided pleuritic chest discomfort, weakness, positive ANA and ...

Last Updated: 30 Nov 2015

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Interstitial lung disease in systemic sclerosis: where do we stand?
 

Author(s): Susanna Cappelli, Silvia Bellando Randone, Gianna Camiciottoli, Amato De Paulis, Serena Guiducci, Marco Matucci-Cerinic

Journal: Eur Respir Rev. 2015 Sep;24(137):411-9.

 

Interstitial lung disease (ILD) is common in systemic sclerosis (SSc) patients and despite recent advances in the treatment is, at present, the major cause of death. Today, an early diagnosis of ILD is possible, and is mandatory to improve the prognosis of the disease. Pulmonary function ...

Last Updated: 1 Sep 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Role of Rheumatological Evaluation in the Management of Patients With Interstitial Lung Disease
 

Status: Recruiting

Condition Summary: Interstitial Lung Disease; Idiopathic Pulmonary Fibrosis; Connective Tissue Disease

 

Last Updated: 8 Apr 2015

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A Study of the Natural Progression of Interstitial Lung Disease (ILD)
 

Status: Recruiting

Condition Summary: Interstitial Lung Diseases; Idiopathic Pulmonary Fibrosis; Sarcoidosis

 

Last Updated: 13 Sep 2012

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Cyclophosphamide Systemic Sclerosis Associated Interstitial Lung Disease
 

Status: Recruiting

Condition Summary: Systemic Sclerosis; Scleroderma; Interstitial Lung Disease; Lung Fibrosis

 

Last Updated: 14 Sep 2016

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