Insulinoma

Common Name(s)

Insulinoma

An insulinoma is a tumor (growth) on the pancreas. It is usually benign, although it can occasionally be malignant (cancerous). The pancreas is responsible for the production of insulin, a messenger that tells the body to break down sugars to make energy needed for daily life. When there is a tumor on the pancreas, the pancreas may begin to produce too much insulin. When a person has too much insulin, their blood-sugar level can become very low, potentially causing seizures or confusion. Symptoms of insulinomas include anxiety, confusion, dizziness, headaches, and sweating. Treatment for insulinomas is usually surgery to remove the tumor as well as certain medications. With appropriate management, people with insulinomas can live full healthy lives.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Insulinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Insulinoma" returned 272 free, full-text research articles on human participants. First 3 results:

Paroxysmal Hypertension Induced by an Insulinoma.
 

Author(s): Ko Harada, Yoshihisa Hanayama, Kou Hasegawa, Masaya Iwamuro, Hideharu Hagiya, Ryuichi Yoshida, Fumio Otsuka

Journal: Intern. Med.. 2017 ;56(4):413-417.

 

Insulinoma is a rare, usually benign, pancreatic neuroendocrine tumor. The clinical features of an insulinoma are fasting hypoglycemia with neuroglycopenic symptoms including confusion and unusual behavior, while hypertension is usually not associated with the disease. We herein report ...

Last Updated: 16 Feb 2017

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Diagnosis of insulinoma using the ratios of serum concentrations of insulin and C-peptide to glucose during a 5-hour oral glucose tolerance test.
 

Author(s): Xu Li, Feng Zhang, Haibing Chen, Haoyong Yu, Jian Zhou, Ming Li, Qing Li, Lianxi Li, Jun Yin, Fang Liu, Yuqian Bao, Junfeng Han, Weiping Jia

Journal: Endocr. J.. 2017 Jan;64(1):49-57.

 

The 72-hour fast test is the current standard for the diagnosis of insulinoma. However, to conduct this test patients require hospitalization due to the chance of severe hypoglycemic episodes. Thus, it is costly and stressful for the patient. An out-patient test would serve the patient ...

Last Updated: 11 Oct 2016

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Multiple Endocrine Neoplasia Type 1 Presenting as Hypoglycemia due to Insulinoma.
 

Author(s): Eun Byul Kwon, Hwal Rim Jeong, Young Seok Shim, Hae Sang Lee, Jin Soon Hwang

Journal: J. Korean Med. Sci.. 2016 Jun;31(6):1003-6.

 

Multiple endocrine neoplasia (MEN) mutation is an autosomal dominant disorder characterized by the occurrence of parathyroid, pancreatic islet, and anterior pituitary tumors. The incidence of insulinoma in MEN is relatively uncommon, and there have been a few cases of MEN manifested ...

Last Updated: 1 Jun 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Insulinoma" returned 15 free, full-text review articles on human participants. First 3 results:

Insulinoma After Bariatric Surgery: Diagnostic Dilemma and Therapeutic Approaches.
 

Author(s): Christopher M Mulla, Alessandra Storino, Eric U Yee, David Lautz, Mandeep S Sawnhey, A James Moser, Mary-Elizabeth Patti

Journal: Obes Surg. 2016 Apr;26(4):874-81.

 

Hypoglycemia is increasingly recognized as a complication of bariatric surgery. Typically, hypoglycemia does not appear immediately postoperatively, but rather more than 1 year later, and usually occurs 1-3 h after meals. While rare, insulinoma has been reported after bariatric ...

Last Updated: 30 Mar 2016

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Long-standing insulinoma: two case reports and review of the literature.
 

Author(s): Mohamed Tarchouli, Abdelmounaim Ait Ali, Moulay Brahim Ratbi, Mohamed said Belhamidi, Mohamed Essarghini, El Mehdi Aboulfeth, Mohamed Bouzroud, Yassir Sbitti, Mohamed Oukabli, Mohammed Elfahssi, Khalid Sair

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Insulinomas are rare pancreatic endocrine tumors. Most are benign and solitary. However, the nonspecific symptoms and small size of these tumors led to difficulties of diagnosis and localization.

Last Updated: 16 Sep 2015

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Insulinoma Masquerading as Rapid Eye Movement Sleep Behavior Disorder: Case Series and Literature Review.
 

Author(s): Keisuke Suzuki, Akiko Kawasaki, Masayuki Miyamoto, Tomoyuki Miyamoto, Takashi Kanbayashi, Masatoshi Sato, Tetsuo Shimizu, Koichi Hirata

Journal: Medicine (Baltimore). 2015 Jun;94(25):e1065.

 

Insulinoma is a rare endocrine tumor that can cause a wide variety of symptoms, including abnormal nocturnal behavior. We report on 3 patients with insulinoma who presented with abnormal nocturnal behavior and injury during sleep, which simulated rapid eye movement (REM) sleep behavior ...

Last Updated: 25 Jun 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

68Ga-NOTA-exendin-4 PET/CT for the Localization of Insulinoma and Diagnosis of Nesidioblastosis
 

Status: Recruiting

Condition Summary: Insulinoma; Nesidioblastosis

 

Last Updated: 24 Sep 2015

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Diagnosing and Treating Low Blood Sugar Levels
 

Status: Recruiting

Condition Summary: Hypoglycemia; Insulinoma

 

Last Updated: 20 Apr 2017

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New Imaging Procedure for the Localisation of Insulinoma and Transplanted Islet Cells
 

Status: Recruiting

Condition Summary: Endogenous Hyperinsulinaemic Hypoglycaemia; Transplanted Islet Cells

 

Last Updated: 2 Nov 2016

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