Insulinoma

Common Name(s)

Insulinoma

An insulinoma is a tumor (growth) on the pancreas. It is usually benign, although it can occasionally be malignant (cancerous). The pancreas is responsible for the production of insulin, a messenger that tells the body to break down sugars to make energy needed for daily life. When there is a tumor on the pancreas, the pancreas may begin to produce too much insulin. When a person has too much insulin, their blood-sugar level can become very low, potentially causing seizures or confusion. Symptoms of insulinomas include anxiety, confusion, dizziness, headaches, and sweating. Treatment for insulinomas is usually surgery to remove the tumor as well as certain medications. With appropriate management, people with insulinomas can live full healthy lives.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Insulinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Insulinoma" returned 238 free, full-text research articles on human participants. First 3 results:

Insulinoma diagnosed as drug-refractory epilepsy in an adolescent boy: a case report.
 

Author(s): Emőke Horváth, H Gozar, Liliana Chira, Iulia Dunca, Eva Kiss, Z Pávai

Journal: Rom J Morphol Embryol. 2013 ;54(4):1147-51.

 

Solitary insulinoma is a rare pancreatic tumor in all age groups with an estimated incidence of 1 in 250 000 persons a year. It is even rarely in childhood and mostly shows benign behavior. Cases with uncertain or malignant biology are extremely rare with less than 30 cases described ...

Last Updated: 8 Jan 2014

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[A case of elderly-onset type 1 diabetes mellitus: negative for antiglutamic acid dehydrogenase antibody and positive insulinoma-associated tyrosine phosphatase-like protein-2 antibody].
 

Author(s): Yuko Chiba, Jeong Ynie, Yoshiyuki Kimbara, Yoshiaki Tamura, Seijiro Mori, Hideki Ito, Atsushi Araki

Journal: Nihon Ronen Igakkai Zasshi. 2013 ;50(3):404-8.

 

An 83-year-old Japanese woman given a diagnosis of type 2 diabetes mellitus 3 years previously was hospitalized for markedly elevated plasma glucose (386 mg/dl) and glycated hemoglobin (9.3%) levels. Laboratory study results showed urinary connecting peptide immunoreactivity (CPR) ...

Last Updated: 27 Aug 2013

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Insulinoma-associated 1a (Insm1a) is required for photoreceptor differentiation in the zebrafish retina.
 

Author(s): Marie A Forbes-Osborne, Stephen G Wilson, Ann C Morris

Journal: Dev. Biol.. 2013 Aug;380(2):157-71.

 

The zinc-finger transcription factor insulinoma-associated 1 (Insm1, previously IA-1) is expressed in the developing nervous and neuroendocrine systems, and is required for cell type specific differentiation. Expression of Insm1 is largely absent in the adult, although it is present ...

Last Updated: 5 Jul 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Insulinoma" returned 11 free, full-text review articles on human participants. First 3 results:

Refractory idiopathic non-insulinoma pancreatogenous hypoglycemia in an adult: case report and review of the literature.
 

Author(s): Cornelia Then, Yun-Chung Nam-Apostolopoulos, Jochen Seissler, Andreas Lechner

Journal:

 

Non-insulinoma pancreatogenous hypoglycemia is a rare cause of spontaneous hypoglycemia in adults. The ideal diagnostic and therapeutic approach is still controversial, not least because most reported cases lack long-term follow-up.

Last Updated: 14 May 2013

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Diagnosis and management of insulinoma.
 

Author(s): Takehiro Okabayashi, Yasuo Shima, Tatsuaki Sumiyoshi, Akihito Kozuki, Satoshi Ito, Yasuhiro Ogawa, Michiya Kobayashi, Kazuhiro Hanazaki

Journal: World J. Gastroenterol.. 2013 Feb;19(6):829-37.

 

Insulinomas, the most common cause of hypoglycemia related to endogenous hyperinsulinism, occur in 1-4 people per million of the general population. Common autonomic symptoms of insulinoma include diaphroresis, tremor, and palpitations, whereas neuroglycopenenic symptoms include confusion, ...

Last Updated: 22 Feb 2013

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Concurrent insulinoma and pancreatic adenocarcinoma: report of a rare case and review of the literature.
 

Author(s): Panagiotis G Athanasopoulos, George Polymeneas, Dionysios Dellaportas, George Mastorakos, Evi Kairi, Dionysios Voros

Journal:

 

Pancreatic adenocarcinoma is the 5th leading cause of cancer-related death in Western countries and insulinomas are rare endocrine neoplasms of the pancreas. The concurrent appearance of pancreatic adenocarcinoma and insulinoma is very rare and to the best of our knowledge has never ...

Last Updated: 10 Feb 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Whole Body 111In-exendin-4 Imaging Study in Insulinoma Patients
 

Status: Recruiting

Condition Summary: Hyperinsulinism; Hypoglycemia; Insulinoma

 

Last Updated: 29 Jun 2010

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Diagnosing and Treating Low Blood Sugar Levels
 

Status: Recruiting

Condition Summary: Hypoglycemia; Insulinoma

 

Last Updated: 14 Mar 2014

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Ziv-Aflibercept in Treating and Computed Tomography Perfusion Imaging in Predicting Response in Patients With Pancreatic Neuroendocrine Tumors That Are Metastatic or Cannot Be Removed By Surgery
 

Status: Recruiting

Condition Summary: Gastrinoma; Glucagonoma; Insulinoma; Pancreatic Polypeptide Tumor; Recurrent Islet Cell Carcinoma; Somatostatinoma

 

Last Updated: 15 Jul 2014

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