Insulinoma

Common Name(s)

Insulinoma

An insulinoma is a tumor (growth) on the pancreas. It is usually benign, although it can occasionally be malignant (cancerous). The pancreas is responsible for the production of insulin, a messenger that tells the body to break down sugars to make energy needed for daily life. When there is a tumor on the pancreas, the pancreas may begin to produce too much insulin. When a person has too much insulin, their blood-sugar level can become very low, potentially causing seizures or confusion. Symptoms of insulinomas include anxiety, confusion, dizziness, headaches, and sweating. Treatment for insulinomas is usually surgery to remove the tumor as well as certain medications. With appropriate management, people with insulinomas can live full healthy lives.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Insulinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Insulinoma" returned 235 free, full-text research articles on human participants. First 3 results:

A rare case of insulinoma presenting with postprandial hypoglycemia.
 

Author(s): Aditya V Shreenivas, Vivien Leung

Journal:

 

Although fasting hypoglycemia has historically been considered the hallmark of insulinoma, postprandial hypoglycemia has also been occasionally reported as the predominant feature. We report a rare case of an insulinoma diagnosed in an individual presenting exclusively with postprandial ...

Last Updated: 10 Nov 2014

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Prompt resolution of hypoglycemia by hepatic transarterial embolization for malignant insulinoma with multiple liver metastases.
 

Author(s): Shinichiro Muro, Junichiro Nasu, Ryo Harada, Minoru Matsubara, Asuka Nakarai, Hiromitsu Kanzaki, Kouichiro Tsutsumi, Hironari Kato, Takehiro Tanaka, Hiroyasu Fujiwara, Masatoshi Uno, Hiroyuki Okada, Kazuhide Yamamoto

Journal: Acta Med. Okayama. 2014 ;68(5):303-6.

 

A 45-year-old female who presented with loss of consciousness and a cold sweat was found to have a pancreatic tumor and multiple liver metastases. Laboratory studies showed marked hypoglycemia and inappropriately elevated serum insulin, C-peptide, and serum tumor markers. Fine needle ...

Last Updated: 23 Oct 2014

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Relevant infrastructural alterations in a pancreatic neuroendocrine tumor: an insulinoma case.
 

Author(s): Gabriel-Valeriu Mirancea, Ana-Maria Moroşanu, Simona Carniciu, Simona Dima, Nicolae Bacalbaşa, Irinel Popescu, Constantin Ionescu-Tîrgovişte, Nicolae Mirancea

Journal: Rom J Morphol Embryol. 2014 ;55(2 Suppl):659-68.

 

In this study, we focus our interest on some peculiar infrastructural abnormalities detected in an insulinoma case. Tumor pancreatic endocrine cells proliferated detrimental to exocrine counterpart, so that extensive areas of prevalent β-tumor cells can be seen. Two phenotypes of ...

Last Updated: 2 Sep 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Insulinoma" returned 11 free, full-text review articles on human participants. First 3 results:

Sporadic insulinoma in a 10-year-old boy: a case report and literature review.
 

Author(s): Ahmed Abu-Zaid, Lama Abdulhamid Alghuneim, Mona Tarek Metawee, Ragaa Osama Elkabbani, Hadeel Almana, Tarek Amin, Ayman Azzam

Journal:

 

Insulinoma is an exceedingly uncommon pancreatic islet cell neuroendocrine tumor. Its estimated incidence is approximately four cases per million individuals per year.

Last Updated: 13 Jan 2014

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Refractory idiopathic non-insulinoma pancreatogenous hypoglycemia in an adult: case report and review of the literature.
 

Author(s): Cornelia Then, Yun-Chung Nam-Apostolopoulos, Jochen Seissler, Andreas Lechner

Journal:

 

Non-insulinoma pancreatogenous hypoglycemia is a rare cause of spontaneous hypoglycemia in adults. The ideal diagnostic and therapeutic approach is still controversial, not least because most reported cases lack long-term follow-up.

Last Updated: 14 May 2013

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Diagnosis and management of insulinoma.
 

Author(s): Takehiro Okabayashi, Yasuo Shima, Tatsuaki Sumiyoshi, Akihito Kozuki, Satoshi Ito, Yasuhiro Ogawa, Michiya Kobayashi, Kazuhiro Hanazaki

Journal: World J. Gastroenterol.. 2013 Feb;19(6):829-37.

 

Insulinomas, the most common cause of hypoglycemia related to endogenous hyperinsulinism, occur in 1-4 people per million of the general population. Common autonomic symptoms of insulinoma include diaphroresis, tremor, and palpitations, whereas neuroglycopenenic symptoms include confusion, ...

Last Updated: 22 Feb 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Diagnosing and Treating Low Blood Sugar Levels
 

Status: Recruiting

Condition Summary: Hypoglycemia; Insulinoma

 

Last Updated: 28 Aug 2015

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New Imaging Procedure for the Localisation of Insulinoma and Transplanted Islet Cells
 

Status: Recruiting

Condition Summary: Endogenous Hyperinsulinaemic Hypoglycaemia; Transplanted Islet Cells

 

Last Updated: 28 Apr 2015

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[18 F]-6-L-fluorodihydroxyphenylalanine (18F-FDOPA) Positron Emission Tomography (PET) in Neuroendocrine Tumours
 

Status: Available

Condition Summary: Thyroid Cancer, Medullary; Carcinoid Tumor; Pheochromocytoma; Paraganglioma; Insulinoma; Neuroblastoma

 

Last Updated: 27 Apr 2015

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