Insulinoma

Common Name(s)

Insulinoma

An insulinoma is a tumor (growth) on the pancreas. It is usually benign, although it can occasionally be malignant (cancerous). The pancreas is responsible for the production of insulin, a messenger that tells the body to break down sugars to make energy needed for daily life. When there is a tumor on the pancreas, the pancreas may begin to produce too much insulin. When a person has too much insulin, their blood-sugar level can become very low, potentially causing seizures or confusion. Symptoms of insulinomas include anxiety, confusion, dizziness, headaches, and sweating. Treatment for insulinomas is usually surgery to remove the tumor as well as certain medications. With appropriate management, people with insulinomas can live full healthy lives.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Insulinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Insulinoma" returned 262 free, full-text research articles on human participants. First 3 results:

Insulinoma in a patient with type 2 diabetes mellitus.
 

Author(s): Shahnaz Ghafoori, Mahnaz Lankarani

Journal: Acta Med Iran. 2015 ;53(5):317-9.

 

Insulinoma in a patient with pre-existing diabetes is extremely rare. Only a small number of cases have been reported all over the world. We report a case of insulinoma in a patient with type 2 diabetes. A 63-year-old female was diagnosed to have diabetes mellitus six years ago, she ...

Last Updated: 30 May 2015

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Laparoscope resection of retroperitoneal ectopic insulinoma: a rare case.
 

Author(s): Jie Liu, Cheng-Wu Zhang, De-Fei Hong, Jia Wu, Hong-Guo Yang, Yuan Chen, Da-Jian Zhao, Yu-Hua Zhang

Journal: World J. Gastroenterol.. 2015 Apr;21(14):4413-8.

 

Ectopic insulinoma is a very rare and dormant tumor. Here we report the case of a 79-year-old female who presented with repeated episodes of hypoglycemia and was diagnosed with insulinoma based on laboratory and imaging examinations. Computed tomography and positron emission tomography ...

Last Updated: 20 Apr 2015

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Nutritional energy stimulates NAD+ production to promote tankyrase-mediated PARsylation in insulinoma cells.
 

Author(s): Linlin Zhong, Tsung-Yin J Yeh, Jun Hao, Nasim Pourtabatabaei, Sushil K Mahata, Jianhua Shao, Steven D Chessler, Nai-Wen Chi

Journal:

 

The poly-ADP-ribosylation (PARsylation) activity of tankyrase (TNKS) regulates diverse physiological processes including energy metabolism and wnt/β-catenin signaling. This TNKS activity uses NAD+ as a co-substrate to post-translationally modify various acceptor proteins including ...

Last Updated: 16 Apr 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Insulinoma" returned 13 free, full-text review articles on human participants. First 3 results:

Insulinoma Masquerading as Rapid Eye Movement Sleep Behavior Disorder: Case Series and Literature Review.
 

Author(s): Keisuke Suzuki, Akiko Kawasaki, Masayuki Miyamoto, Tomoyuki Miyamoto, Takashi Kanbayashi, Masatoshi Sato, Tetsuo Shimizu, Koichi Hirata

Journal: Medicine (Baltimore). 2015 Jun;94(25):e1065.

 

Insulinoma is a rare endocrine tumor that can cause a wide variety of symptoms, including abnormal nocturnal behavior. We report on 3 patients with insulinoma who presented with abnormal nocturnal behavior and injury during sleep, which simulated rapid eye movement (REM) sleep behavior ...

Last Updated: 25 Jun 2015

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Sporadic insulinoma in a 10-year-old boy: a case report and literature review.
 

Author(s): Ahmed Abu-Zaid, Lama Abdulhamid Alghuneim, Mona Tarek Metawee, Ragaa Osama Elkabbani, Hadeel Almana, Tarek Amin, Ayman Azzam

Journal:

 

Insulinoma is an exceedingly uncommon pancreatic islet cell neuroendocrine tumor. Its estimated incidence is approximately four cases per million individuals per year.

Last Updated: 13 Jan 2014

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Refractory idiopathic non-insulinoma pancreatogenous hypoglycemia in an adult: case report and review of the literature.
 

Author(s): Cornelia Then, Yun-Chung Nam-Apostolopoulos, Jochen Seissler, Andreas Lechner

Journal:

 

Non-insulinoma pancreatogenous hypoglycemia is a rare cause of spontaneous hypoglycemia in adults. The ideal diagnostic and therapeutic approach is still controversial, not least because most reported cases lack long-term follow-up.

Last Updated: 14 May 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

68Ga-NOTA-exendin-4 PET/CT for the Localization of Insulinoma and Diagnosis of Nesidioblastosis
 

Status: Recruiting

Condition Summary: Insulinoma; Nesidioblastosis

 

Last Updated: 24 Sep 2015

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Diagnosing and Treating Low Blood Sugar Levels
 

Status: Recruiting

Condition Summary: Hypoglycemia; Insulinoma

 

Last Updated: 28 Aug 2015

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New Imaging Procedure for the Localisation of Insulinoma and Transplanted Islet Cells
 

Status: Recruiting

Condition Summary: Endogenous Hyperinsulinaemic Hypoglycaemia; Transplanted Islet Cells

 

Last Updated: 28 Oct 2015

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